In the sequel, Mikey's parents try to get him interested in potty training by singing a song about the potty. Mikey snarks that it's not appropriate subject matter for a musical. Flash forward to 2001, we get the Broadway musical Urinetown, a musical about urination that also lampshades how inappropriate the subject matter is for a musical.
During the delivery, Julie's umbilical cord gets tangled around her neck and she struggles to breathe, resulting in a more distressing and bloody delivery scene than the original.
Mikey has a nightmare where a miniature Satan shows up in his toy collection and turns his teddy bear into a fanged and clawed monster.
Mr. Toilet Man, a furry fanged toilet that harasses Mikey to pee in him and spits disgusting blue goo as he talks, so much that one woman made the news because she feared going to the bathroom after watching the film as a kid.
Sequelitis: The first movie was a commercial smash and moderately well-received critically (including two thumbs up from Siskel & Ebert); the more outlandish sequels, very much less so to diminishing returns on both fronts.
Values Dissonance: In the first film, Mollie blowing up at James for lighting a cigarette in her apartment is meant to be part of her neuroticism as a new mother. James even mocks her for it. Today, that would be seen as not only a perfectly reasonable thing to be upset about, but Mollie would be criticized as a neglectful mother for allowing it, given the past few decades worth of research on the effects of secondhand smoke.
What Do You Mean, It's Not for Kids?: The films are about talking babies (and talking dogs in the third case). They're commonly shown on family-friendly networks, but they're full of adult humor and weren't intended for children.
because she feared going to the bathroom after watching the film as a kid.