Memetic Mutation: "Just give me five minutes with the genius who _____!" based on the panel of Inspector Gill exclaiming, "Just give me five minutes with the genius who decided fish should use stairs!" in the first comic.
Values Dissonance: In issue ten, a desert-dweller Gill meets while in self-imposed exile asks him, albeit indirectly, if he's a homosexual, to which he takes loud, disgusted exception. Just an issue later one of Gill's new pal's hulking fellow desert-dwellers voices his own assumption the detective is one of those "big-city queer-boys".
Narm: Just try to say the title of this show out loud and then remind yourself that it's supposed to be for adults.
Then there's the never-ending conveyor belt of fish-themed jokes, idioms, and puns. From the names of characters, to casual dialogue, there's always something that replaces otherwise normal conversation with a fish term, and it often sounds just plain odd. In particular is Angel's Shout-Out to Jessica Rabbit (who Angel is an Expy of), where she defends herself saying "I'm not bad, I just smell that way." Sure, fish being smelly is Truth in Television, but with the line coming from a smoking hot bombshell who's known for being lusted after (and possibly sleeping with) every guy in town, it comes off more as a gag about how women's privates can smell bad like fish at times.
Uncertain Audience: A common criticism of the show was that it didn't know if it wanted to appeal to kids or adults, since it was too inappropriate for children, but too much like a typical kids' show for adults.
What Do You Mean, It's Not for Kids?: It was meant to compete with The Simpsons as the next big prime-time animated show, but it still looked and felt like a typical Hanna-Barbera children's show. If it was aimed towards kids, it could've been a bit more successful.
. Just an issue later one of Gill's new pal's hulking fellow desert-dwellers voices his own assumption the detective is one of those "big-city queer-boys".