Harsher in Hindsight: Peter makes a very personal and cruel Prank Call to Joe that includes the line "Wheelie wheelie stupid head, bet you wish that you were dead!" This hits much harder in later seasons when it's revealed that Joe has become borderline suicidal as a result of his disability, and as shown as early as the following season's "The Blind Side", the thought of dying makes Joe happy.
Nightmare Fuel: From Evil Stewie mercilessly killing people (and in horrifying ways, such as cutting a woman in half) to Meg attempting to cripple herself for love.
Squick: Meg breastfeeding Susie causes Joe to freak out.
