YMMV / Family Guy S 1 E 4 Mind Over Murder

• Designated Villain: Peter, after he punches a pregnant woman who looks like a man. We're supposed to be angry at Peter, but he did not know that the person he punched was a woman, let alone pregnant. Plus, she was being unapologetically rude to him and his thirteen year old son. Also, he is called out for trying to set the other housewives onto Lois, despite the fact they confronted him over it. Lois also insists the whole singing act was innocent fun, despite the fact she was flirting and having nothing against having the audience ogle her and make Peter jealous for neglecting her.
• Harsher in Hindsight: The climax of the episode has Quagmire flick a cigar butt in the bar trashcan, setting it alight and torching the basement. Peter and Lois are trapped, saved only by Stewie's time travel device. Four years after this episode aired, a bar in Rhode Island caught fire (albeit due to misplaced pyrotechnics), killing a hundred people.
• Shallow Parody: A parody show Peter claims is a composite of two shows is Homicide: Life On Sesame Street. While it mentions Homicide by name, given the gratuitous nudity and characters in bed, it's more reminiscent of rival show NYPD Blue.