Pre-Season 1 Speculation
The spin-off will take place at Grady Memorial Hospital.
The characters whom Kirkman named might end up at that setting introduced in season 5.- Jossed. It will take place in Los Angeles, California
The Morales family will appear in the spin-off.
They said in season 1 that they would be searching for their family, so maybe this will reveal their fates. Sean Cabrera and his son Cody are related to the Morales family.
Sean is described as a Latino, so it is a possibility.- Jossed. Their finalized incarnations, Travis and Chris Manawa, are Maori.
Part of the spin-off will take place in Alabama.
This is going off of the previous two WMG since the Morales family said that they were heading for Birmingham.- Jossed. It's in Los Angeles.
The show will begin in Dodge City, Kansas.
It has been said that Ashley Thompkins believes that "it's time to get out of Dodge." Maybe the Thompkins family is from Dodge City, Kansas.- Jossed. It will be in Los Angeles.
Nick will take a dark path similar to Carl from the comics.
He is described as a "screwed-up teenage son" in the original casting call. Andrea Chapman will be similar to Andrea from the comics.
Meaning that she will be a Lady of War who does not make stupid decisions as the Andrea on the parent show did.- Jossed. Not only was Andrea Chapman renamed Liza Ortiz and given none of comic book Andrea's character traits, but she ended up being killed off in the first season finale.
Chase and Kelly will appear.
They were introduced in the Cold Storage webisodes. Maybe their fates will be revealed.- Unlikely for the spin-off as it takes place in Los Angeles, but possible for the main series.
Paul will appear.
He was last seen in The Oath webisodes. Maybe his fate will be revealed.- Unlikely for the spin-off as it takes place in Los Angeles, though possible for the main series.
Jesse Pinkman will appear.
There have been several hints that the two shows exist in the same universe (Merle's drug stash containing "Sky Blue" meth and Daryl's description of Merle's dealer matching Jesse).Since the spin-off will take place in Los Angeles, it's more likely for him to show up there.
The song "Hollywood Swinging" by Kool And The Gang will appear on the show
While someone is swinging a bat or a sword Season 1 Speculation
At some point some characters will be chased by zombies to a forest...
...And will humorously refuse to enter it, lampshading the original series' standard setting. This will still keep in line with the spinoff's creators' promise of no forests. The military intervention is a Hope Spot
The military erroneously believes that blood or physical contact spreads the virus. This leads to innocent people being quarantined, or at worst exterminated. This leads to another prediction: Patrick Tran will be found dead.
- Confirmed, except for the part about Patrick.
The Turn was caused by Cobalt, or at least had something to do with it.
The name of the 5th episode of the 1st season is going to be called Cobalt. It was also the working title for "Fear The Walking Dead". In a reference to NightOfTheLivingDead1968, the dead will start rising from their graves due to (cobalt) radiation. It's also possible that the walkers were reanimated by nanobots/nanites/some other kind of small machine powered by cobalt, or were somehow created by an organization/government project with the name/acronym Cobalt.- Jossed, as Cobalt is a command for all military to clear LA before the city is firebombed.
Patrick and Susan Tran are related to Kevin Tran.
Meanwhile, in Georgia... Rick Grimes goes into his coma during the first episode of Fear The Walking Dead.
Just guessing. Shame we haven't even heard a radio broadcast in the background about the King County police officer who was shot.- Why would we hear about that? Fear The Walking Dead is set in Los Angeles, so they wouldn't hear the news about a small town cop getting hospitalized thousands of miles away.
- Actually, by the time the spin-off series starts, Rick is already in the coma and has been for at least a week or two prior to first reports of attacks and the eventual full-on outbreak.
The military is good and Madison is misinterpreting their shadiness.
Madison judged the corpses who were killed by the National Guard as healthy people, but in fact, she meant that they were simply not bitten. We know that any person who dies will become a walker, so the National Guard may have been killing people who died of natural causes or who were killed by way of accident or subtle murder. If not, maybe they were trying to attack the National Guard for their weapons and supplies.
Regardless, Madison will get everyone to turn on the National Guard based on her assumption, realizing all too late that they were really here to help. The lieutenant was just being a jerk because the stress of the job was getting to him.
- Jossed. The military was intending to abandon LA and "humanely" execute their prisoners.
Pre-Season 2 Speculation
Strand knows the origins of the infection(or whatever created the walkers).
This explains why he's so mysterious, and why he seems to have power. It also explains how the origins of the zombie apocalypse are going to be explained to the characters. The series will take place outside of Los Angeles
Now that Travis' group has access to a boat, they'll either travel west to Hawaii or north to Alaska to try and avoid walkers.- Confirmed. However, the group is actually headed for San Diego. And later Mexico.
The concept of Ouroboros will somehow connect to the walkers' origins.
Ouroboros is the name of the 3rd episode of Season 2. An Ouroboros is a snake(sometimes a dragon) biting it's own tail in a circle, and it's used as a symbol of infinite recursion, eternity, infinity, and/or rebirth. This will tie into the walkers' origins: They were created by a group or project called Ouroboros as an experiment to reanimate the dead and/or make humans immortal Gone Horribly Right.- Jossed.
Season 2 Speculation
The series, or at least most of Season 2 if not more, will take place entirely aboard the Abigail.
The week-to-week plots will have the Abigail encountering various groups of survivors both on sea and on land. No landside location will provide a suitable home for the denizens of the Abigail, however, and they will always have to leave by the end of the episode—sometimes adding a new cast member to the Abigail's passenger contingent. The voyage of the Abigail will start to evoke Star Trek: Voyager by the end of Season 2.- Jossed. By the sixth episode it seems the group has left behind the Abigail for good.
Alex is a part of Connor's crew.
She was likely picked up after being left stranded and she would certainly have a motive to give them all the information that she could. It would explain how they knew Daniel and Nick's names, since she met them personally. And it would explain how they didn't seem to know Strand's name and why they kept referring him to the captain, since she never got his name.- confirmed in S2E5 "Captive".
The main characters eventually become The Whisperers.
More specifically, Madison will become Alpha. Travis could either become Beta, or die somewhere along the line and be replaced by someone else for Madison, but given his recent dark turn with certain events toward the end of season 2, it's becoming more likely that Travis will become Beta (perhaps Chris' words will linger in his mind). Madison has a daughter who could fit a sort Lydia from the comics role. Madison shows a lot of care and doting protectiveness for Nick,, but Alicia often complains that she exists and Madison won't show that care for her. This sort of behavior could lead to Madison making Alicia fend for herself to "toughen her up" like Lydia from the comics. The fact that they're so comfortable with killing now, and the way that they were forced to evacuate the hotel, could lead to Madison/Alpha's belief that they shouldn't live in shelters and belong in this savage environment.The timing with The Walking Dead is perfect, as they have plenty of time to tell their story and end it before The Whisperers show up in The Walking Dead's story. It would be the ultimate Easter Egg for fans of both shows.
- Since Travis is dead, I'm guessing Nick or Strand will be Beta, or Strand will be Beta and Nick will declare himself to be the Omega.
- Jossed. Nothing like that ever happens.
Season 4 Speculation
- It will turn out that John Dorie is not an ex-cop. His story about shooting an armed robber in the leg will be revealed to be a fabrication. Persons trained in the use of deadly force, including police officers, are trained to stop a threat by shooting at center-of-mass, i.e. the torso. "Winging" someone in the manner that Dorie relates, while plausible given his Improbable Aiming Skills, would run counter to training as a police officer. The idea that one can stop an attack by "shooting to wound", e.g. in the leg, is a common Hollywood error, but TWD franchise mostly shows their work when it comes to guns, so it's unlikely that this is an error by the writers/showrunners.
Pre-Season 8 Speculation
This season will tie into Tales of the Walking Dead.
Specifically to the episode "Amy; Dr. Everett". That episode is set in the Wiregrass region
of the Gulf Coast, while we know that PADRE is operating across the Gulf Coast. Amy implies that the authority that she and her friends are trying to get away from is iron-fisted, which fits with PADRE's ruthless nature. And the trailer for Season 8 shows someone carrying a severed walker head, which calls back to Amy and Everett both mentioning "headhunters" who steal heads from walkers and take them back to the populated region outside the Dead Sector. All this together would suggest that PADRE was the group that Amy was trying to abandon, which makes it possible that Morgan's group might meet Everett while fighting PADRE. Misc
Titus Welliver, Paula Malcolmson, Robin Weigert, and/or Keone Young will be cast at some point.
Like Kim Dickens, Dayton Callie, and Ray McKinnon, they've all been in both Deadwood and Sons of Anarchy.