Regarding "The End?"
A popular theory ahead of the reveal on September 21st (2018) is that Daredevil will die, and that's very possible, but going even further than that...- Apparently confirmed by the announcement of Soule's "Death of Daredevil" arc, which will conclude his run.
Blindspot will assume the Daredevil mantle
He's been a part of Charles Soule's run since the beginning as Matt's apprentice, and has since become (functionally) blind, so it wouldn't come out of nowhere. Plus he's got some added mojo coming off his (civilian) appearance in Iron Fist season two. Alternatively, Mike Murdock will become the new Daredevil
Matt's (formerly) fictional twin brother, recently brought to life by Reader, will assume the mantle, perhaps becoming a sort of "Superior" Daredevil.