Fry's Anchovie Pizza

Fry buys the last can of anchovies in existence to serve to his friends on a pizza. He enjoys them, but his friends (excluding Zoidberg, of course) do not (which he puts down to them being an "acquired taste"). Zoidberg's species are actually ADDICTED to anchovies and are the reason the species is extinct in the future. The last shot of the episode is an enraged Zoidberg advancing on Fry, angrily demanding more anchovies, despite the species being extinct.

Example of:
Anchovies Are Abhorrent