Unrequited Love Switcheroos in Webcomics.
- Big Ethel Energy: Just like in the comics, Betty had a Single-Target Sexuality towards Archie, even settling for going to Homecoming alone when he instead asked Veronica, whom he often preferred to Betty. Ten years later, Betty and Archie have not only broken up, Betty barely talks to him anymore, and even actively rebuffs his attempts to reach out, while he seems to really miss her company.
- Lucy of Bittersweet Candy Bowl is the queen of this; not only does Mike pursue her for years only for her to keep pushing him away until she accidentally helps get him back with his other love interest Sandy, she also manages to convince him that she doesn't actually like him.
- Dave/Margaret/Blue from College Roomies from Hell!!!. For the first few years of the comic's run, Dave pines intensely for Margaret, who is almost completely uninterested in reciprocating, while he sees Blue as an Abhorrent Admirer when she falls in lust at first sight with him. Eventually his attitude toward Blue shifts, and they become a couple... just as Margaret begins acknowledging to herself that she is pushing Dave away primarily as a defense mechanism and that she does feel something for him.
- Eerie Cuties: Initially, Layla had no interest in Dio
, whom her parents had arranged for her to marry, and chose to remain with her boyfriend, Kade. But seeing Dio get beat up, by Ash, made her realize she had feelings for him after all. Except Dio had been zapped by Mel's wand, causing him and Ash to fall in love with each other! Which has left her in the humiliating position of having to compete with another guy for Dio's affections. - Girl Genius: Initially Moloch has a crush on Sanaa but she seems to think he's rather useless. However, after he Takes a Level in Badass and becomes Agatha's chief minion Sanaa seems to be attracted to him and he seems to be over his crush. And unfortunately for her, there could end up being some competition.
- In El Goonish Shive, this is briefly shown as one of the effects of a "swish" of a magic wand. No one in-universe is aware of any of the effects of the wand because that is how it works. While that example is not canon, there is one canon example. Justin is in love with Elliot, who is straight. However, when Elliot develops magical powers that mostly revolve around him turning into a girl, one of his female alter-egos is clearly attracted to Justin, making this a case of Incompatible Orientation twice between the same two people.
- At first, Annie seemed indifferent to Jack's attempt to flirt with her in chapter 31 of Gunnerkrigg Court. Then, by the end of chapter 34, this happens.
- In Homestuck, Kanaya has a crush on Vriska, who's in love with Tavros. Long after Kanaya "Discard[s] The Preposterous Infatuation" Vriska is punched across the room by Kanaya and promptly swoons over her.
- Briefly in The Order of the Stick: after Roy's spent time as a woman, he apologizes to Miko for having treated her as a sex object; she expresses interest in him now that he's learned his lesson, but he shuts her down, having realized that she's an arrogant, destructive fanatic and he was only interested in her because he was thinking with the Trouser Titan.
- Jeri Keene in PreTeena is disdainful of Johnson Pinecone's devoted pursuit of her. Until he stops. Then she begins to pursue him.
- Leslie and Robin of Shortpacked! keep switching who wants to have a relationship between them. At first, Robin only has her around in a convoluted plot to get her Straight Gay friend and Leslie actually liked her. Eventually, Robin reciprocated her feelings but Robin cheats on her when on a massive sugar high. Robin wants to get back together, but Leslie doesn't want to despite still having feelings for her. Then Robin mellows into someone Leslie could have a relationship with, only to get together with her old friend Joe just before Leslie could broach the subject. Leslie ends up visiting a parallel universe to rescue Joe's old flame, pretty much resolving the issue.
