Trivia / The Brain That Wouldn't Die

• Follow the Leader: Frankenhooker and The Man with Two Brains.
• Life Imitates Art: Who'd have thought that fifty years after Bill was playing around with the idea of a serum that could allow for complete organ and limb transplants with Jan and his monster, anti-rejection medications have been developed that could allow for things like full facial and double leg transplants? Not to mention nearly every internal organ... so at least in real life, The Extremist Was Right.^note It should be noted that Bill's father had no problem with Bill's goals, simply his methods of experimenting on people.
• Referenced by...:
  • Dominick and Eugene: At Nicky's "birthday party," Larry has Nicky watch The Brain That Wouldn't Die in the kitchen while he has sex with Mrs. Vinson upstairs.
  • No One Lives Forever: In the second game a conversation between two mooks who have been compressed into crate-like abominations by the evil H.A.R.M. organization directly reference this movie by name along with its most famous quote.
    Mook 1: Are you feeling any better today, Chuck?
    Mook 2: No, my deformed friend. Like all quantities, horror has its ultimate, and I am that.
    Mook 1: Hey, that's from The Brain that Wouldn't Die, right? I love that movie! I never thought I'd be able to relate to Jan in the Pan.