- Early Draft Tie-In: Cindy Vortex has her hairstyle reused from the shorts and Jimmy Neutron: Boy Genius.
- Preview Piggybacking: The game comes with previews to Tak 2: The Staff of Dreams, The Sponge Bob Movie Game, The Fairly OddParents: Shadow Showdown and Avatar: The Last Airbender.
- The Original Darrin: Andrea Martin and Crystal Scales reprise Miss Fowl and Libby after having been replaced by Hope Levy in Jimmy Neutron vs. Jimmy Negatron
- What Could Have Been: There was going to be a version for the Xbox but was cancelled.
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