For the 2022 film:
- Descended Creator: Screenwriter Joel Kim Booster as Noah.
- Queer Character, Queer Actor: Most of the cast is queer including Joel Kim Booster (Noah), Bowen Yang (Howie), Conrad Ricamora (Will), James Scully (Charlie), Margaret Cho (Erin), Tomás Matos (Keegan), Nick Adams (Cooper), and Zane Phillips (Dex).