General
- Queer Character, Queer Actor: Diggy, a lesbian, was played by Kiersey Clemons, who's queer.
- Write What You Know: Malcolm has a Nigerian father and grows up in Inglewood. Writer/director Rick Famuyiwa is the son of Nigerian immigrants and grew up in Inglewood.
Specific
- Dope is the first American film to accept bitcoins as payment for tickets, likely due to their use being a major plot point in the movie.