- Adaptation Overdosed: Due to just how iconic Batman's debut story is, "The Case of the Chemical Syndicate" has been retold no less than five different times throughout the decades.
- In 1969, the thirtieth anniversary of the story, a contemporary update written by Mike Friedrich was published in Detective Comics #387 with art by Bob Brown and Joe Giella. Titled "The Cry of Night is — Sudden Death!"
- Another remake was included in Secret Origins #6 (1986) by Roy Thomas and Marshall Rogers, more closely mirroring the original’s plot, with updated art.
- Detective Comics #627 was a special issue that included four different versions of the story: the 1939 original, the 1969 update (retitled "The Cry of Night is — Kill!"), and two new takes on the story, one by Marv Wolfman and Jim Aparo, and another by Alan Grant and Norm Breyfogle.
- Brad Meltzer wrote an updated version of this story with art by Bryan Hitch for the New 52's Detective Comics volume 2 #27 which was released in January 2014 as part of Batman's 75th anniversary. The plot and characters are largely the same as the original, with a twist ending implying Stryker's dip in the acid transforms him into The Joker.
- First Appearance: Of both Batman and Commisionner Gordon.
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