- Channel Hop: David O' Selzneck at MGM originally owned the rights to the play and planned to produce with Greta Garbo and Fredric March starring, but she wasn't interested and did Anna Karenina instead. He also considered Katharine Hepburn.
- Creator's Favorite: Bette Davis said that Judith Traherne was her favourite role to play.
- Method Acting: Bette Davis suffered a nervous breakdown during filming as a result of her crumbling marriage to Harmon Nelson. Reportedly, Hal B. Wallis convinced her that she could actually benefit by using these real-life emotions to enhance her performance.
- Referenced by...: In There's More Than One Way Home, Val rents Dark Victory in an attempt to distract Anna from her worries.
- Romance on the Set: Bette Davis and George Brent had an affair during filming.
- What Could Have Been:
- Barbara Stanwyck lobbied for the role of Judith.
- Bette Davis wanted Spencer Tracy to play Dr. Frederic Steele, but he wasn't available.
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