Tear Jerker / Sword of the Berserk: Guts' Rage

• Nico's story. A simple-minded implied to be mentally retarded boy who was misunderstood by everybody, but still remained his cheerful demeanor regardless of his misfortunes. He died out in the snow from starvation after no one gave him any food, with only his faithful dog to mourn him. His death caused Eriza's own Despair Event Horizon.
• Eriza's suicide by running into a fiery building with Niko's dead body after Balzac's men destroyed her village and the Mandragoran natives she cared for. Her last words before the suicide are especially poignant in showing her desire for peace shattered by her hatred of the men who killed everyone she cared for.
  Eriza: Oh God. Lead me to your and somehow bring peace to these evil sinners!
• Balzac's speech about why he turned out the way he did is intensely eloquent and tragic. He talks about the pain of having to take care of someone you love knowing that they cannot even recognize you, seeking in vain for something that could change them back to how they used to be. Even if he's beyond saving, it's hard not to pity him. It make you think that maybe he's not so different from Guts, and that maybe he's an example of what he could have and might still become.
• Toward the end, after a major Boss fight, we get a major tearjerker between Guts and Casca: After Guts defeats a huge mandragora monster that was possessing her, she regains her memory for a brief moment, since the mandragora makes sane people insane and vice versa in Casca's state. The two can only share a fragment of a moment with each before the possession wears off and Casca reverts back to her insane state, leaving Guts in utter despair once again.