Tear Jerker / Rome

• The undignified treatment of Vercingetorix, the Gallic chieftain strangled at Caesar's Triumph. The man saw his homeland subjugated and his people enslaved, only for his life to end as a humiliating spectacle for Caesar.
• Poor Eirene, after being forced into slavery and sold off to Vorenus's household, she eventually found solace with a fellow slave. Then one day, she found out her master's best friend had bought her freedom and even brought her a gift to celebrate. Only, when she went off to try said gift, said friend brutally murdered her lover out of sheer jealousy. Then, after forgiving the murderer (although not without trying to kill him first), she had a semblance of a loving family life, only to have it brutally cut short as she was poisoned by a jealous Gaia.
• Servillia might be a Jerkass Woobie, but there's something heartbreaking when Caesar, to whom she stayed loyal, even risking death and humiliation to prove said loyalty, ultimately discards her out of politics. Also, her reaction to Brutus's death was to try wearing her death mask before breaking down, weeping that she was 'so tired of sleeping.' She may have been behind a lot of deaths, but it's also obvious that a lot of her pain and suffering could have been avoided.
• Atia when she's publicly scorned by Anthony. At first, she tries to fool herself, excusing Anthony's dismissal as Cleopatra's orders. When assured that it wasn't the case, she breaks down, slaps Vorenus and runs away.
• Posca weeping over Caesar's dead body, calling out for his 'dominus'.
• Brutus's It Has Been an Honor speech to his men and Suicide by Cop.
• Cicero's death, the more so because he knows it's coming and accepts it, but he still asks his killer for a few more moments of life. His one consolation, and it's not much, is that his killer is respectful, considerate and even affable, politely suggesting that Cicero kneel down to make it easier.
• The collapse of Octavian and Octavia's relationship is heartbreaking, in that at one point they were close and loving siblings, even a bit too loving at one point, and she was the only one who tried to protect him from abuse in his childhood. Octavian's drive to obtain power and unwillingness to let go of his grudge against his mother and Marc Antony for humiliating him drives away and terrifies Octavia. Eventually, Octavian ends up having Octavia marry Antony and possibly bear his children for a political scheme, ruins her true love affair with Agrippa, and puts her on house arrest, which eventually and permanently destroys any happy relationship the two once had.
• The arc of Vorenus and Niobe's relationship. It starts out rough, but they both genuinely want to make it work and grow to love each other. Then he learns she lied to him and he cannot keep his temper and it's all over in an instant. Vorenus spends the rest of the show regretting his anger, being loathed by his children, and missing his beloved wife.
• As much of a terrible person as he often was Mark Anthony's final moments are deeply tragic. He wails at the (false) news that Cleopatra is dead and then seemingly comes to some clarity as to how far he has fallen from the Roman hero he once was, stripping off his Egyptian garb and asking Vorenus to help him at least die like a Roman. He tries to gain some comfort from dying somewhere associated with Alexander and when Vorenus tells him It Has Been an Honor Anthony looks genuinely confused as to why he'd ever think that.

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