Spoilers Off applies to all Tear Jerker pages, so all spoilers are unmarked. You Have Been Warned!
- The end of "The Neuralyzer Syndrome," where the neuralyzed K is "renewing his vows" by saying one last goodbye to his father.
- K's father asks if they will ever see each other again and K looks to J, who sadly looks away. They both know it's a final goodbye. Though some of the sting is taken away by the fact that K finds a photo of himself, his father and their prized Mustang in his jacket after his memory is restored.
- Zed has J neutralized as well so he won't miss the neuralized K when his memory is restored.
- The end of "The Inanimate Syndrome" when Agent Aileen leaves. She and Kay both conclude that their respective careers will keep them separated and are apparently resigned to it.J: Fuel fumes really sting the eyes, huh?K: ...yeah.
- Jay's look of horror and disillusionment in "The I Married An Alien Syndrome" when he has found proof that Kay is a traitor. It also prompts him to go somewhat paranoid, chasing down the aliens involved with no backup since, if he couldn't trust Kay, who could he trust?
- The beginning of "The "J" is for James Syndrome" starts off with Jay accidentally going for a joyride in the LTD and getting neuralyzed by the MIB. The worst of it is the fact that as they do it he starts screaming in protest while some agents hold him to keep him from getting away.
- Later, Kay turning up to visit the neuralized Jay. The guy is close to tearing up when he shakes Jay's hand for what he believes to be the last time. And this was before anyone had a clue that Jay had seen the bug queen, so Kay had no ulterior motive other than checking up on his ex partner one last time.
- At the end of "The Quick Clone Syndrome", J creates several Quick Clones to help fight Alpha. In the ensuing battle, one of the Clones is cut in half, and at the end of the battle melts prematurely. The remaining clones actually take a moment to mourn their fellow clone, saying: "When it's your time, it's your time." At the end of the episodes, the clones all decide to spend their remaining lifespan playing basketball together. It's a surprisingly deep look at something the series had until then treated as expendable.
- In "The Neuralizer Syndrome" and "The "J" is for James Syndrome" we get a look at the loved ones of MIB agents. Kay's father and Jay's aunt both had their young relatives vanish with no explanation. Kay's case is even worse since he was sixteen when he disappeared. It was probably concluded that he had been murdered - this was before MIB was a well developed organization, so whatever cover story was provided probably wasn't very elaborate. Fridge Horror in that how many normal people could be waiting for their loved ones who have vanished into MIB?
- Jay's reaction in "The Spectacle Syndrome" when it looks like Kay has been killed. The poor guy looks so lost that the Worms, of all people, try to talk him out of it.
- Florbus, the Alcinian antagonist from "The Psychic Link Syndrome", who isn't malevolent like most of the other antagonists on the show, just suffering from severe mental issues that drive him paranoid.
