- The Nobunaga plot of the movie is a Whole-Plot Reference (or rather a parody) to the Nobunaga OVA of Peacock King, another manga about Japanese exorcists and ghost hunters.
- Daishuu is shown repelling a wraith with his bare fists while yelling "ORA ORA ORA ORA ORA!!".
- Pietro bribes Mikami with the "Condor of Malta" to get her to visit an island in the Mediterranean.
- Early on, part of Pietro's training is shown as performing a "vampire Sho Ryu Ken" inside a waterfall.
- In chapter 56, on page 5, there's a certain spear-wielding boy...
- At one point, Dr. Chaos claims that Isaac Asimov owes him money.
- And then there's Meiko unwittingly emulating the opening of Iron Chef.
- The "Survival Mansion" arc in the manga is pretty much one big shoutout to Resident Evil.
- Chapter 284. Mikami pretty much copies the end to the movie Jaws with a great white shark.
- When Gyakutengou is starting its attack on Myoushinzan, Papilio calls out "This week's surprise mecha!".
- The Tanabata arc is, in part, one big shout-out to Terminator 2: Judgment Day, with milk instead of liquid nitrogen.
- Chapter 371 takes place in 1978 and contains an authorized cameo of a certain mangaka, and how Reiko's mom inspired her to create Lum.
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