- 24: Tarzan fights terrorism.
- 100 Things to Do Before High School: Karmi, Milo, and Little Cato try to achieve their accomplishments before entering high school. Dudley Puppy is the school's counselor.
- Alcatraz: Mr. Big discovers that the infamous prison's inmates have been time-shifted, and now they're pissed. Also starring Hurley and Joan of Arc.
- Ally McBeal: Kitty Walker (Princess Celestia in Switzerland) works at a lawfirm with Lindsey Funke, Mr. Test, and Sailor Saturn. Kitty Celestia dates Eddie and almost marries Larry Paul (who later has a kid with Ms. Bitters). Her past self, daughter Harley Quinn later catches up with her.
- Arrested Development: John F. Kennedy becomes head of his family after his father B.A. Baracus is sent to jail. JFK must now look over his relatives, including son Cody (who crushes on his cousin Courtney), mother Ellen Ripley, brothers Willow and Archie Johnson, and sister Nell Porter (who's married to Chicken). Narrated by Davy Jones.
- After the series was Un-Cancelled and moved to Netflix, Willow became Krillin, while Chicken turned into Lofty.
- The A-Team: The Riddler (later Tim Taylor), Al Bundy (later Foghorn Leghorn), Red Skull, and Gandalf (later Baloo, then Jor-El) drive around in a Cool Car, evading the government and destroying all the property they can.
- Austin & Ally: Reptil and Toph Bei Fong are musicians.
- Barney & Friends: Sonic the Hedgehog teaches kids life lessons and takes them on adventures with the help of Lara Croft and Barnicle Boy.
- Beverly Hills, 90210: Twins Brainy Smurf and Tara move to Beverly Hills. Here they become friends with a lot of people including Heidi, Mark Sloan, Shaggy and Spike.
- The Big Bang Theory: Roommates Mouth McFadden and Drake Parker are two physicists; Blair Waldorf is a waitress who lives across the hall.
- Big Time Rush: Lion-O, Bobby Hill, Draco Malfoy, and Jake Long form a boy band.
- Bones: Kelly Bundy and Norbert solve murder mysteries.
- Boy Meets World: The life of a young boy named Dwight Schrute. He has a best friend, Simba and a girlfriend, later wife, Chloe. Not to mention that Dwight's brother is Captain America.
- Girl Meets World: Dwight and Chloe get married and have two kids, but the focus is on their daughter Arya Stark. Arya's best friend is Ali; and her classmates include Junior, Riley's brother Linus van Pelt, and Badou.
- Buffy the Vampire Slayer: Monica Geller kills vampires under the orders of Andy Dufresne. Despite this, Monica tries to lead a balanced life with her friends Rogue and Dr. Blowhole, sister Sango, and love interests Jason Bourne and Robin (later Daniel-san).
- Charles in Charge: Stu Hopps gets hired as a caretaker to Nozomi Yumehara.
- Cheers: Keiji owns a bar in Boston, where his regular customers are C-19, Garuru the mailman (who was married to Uhura).
- Frasier: (seasons 1-5) Captain Hero (now George Costanza) moves to Seattle with his brother Charlie B. Barkin and their maid Peg Bundy.
- (since season 6) Red Forman and Prince Gumball live with their maid Shauna.
- Criminal Minds: Suspect Behavior: Captain Archer and Xena are FBI profilers.
- Dawson's Creek: Screech, Tweety, Charlotte and Stewie Griffin are four friends living in a small town named Capeside.
- Dead Like Me: After getting killed by a toilet seat, Phoebe Buffay joins a group of Grim Reapers, where she quickly makes friends with Ally McBeal, and when Ally disappears, she ends up having to deal with Rachel Green as a roommate.
- Doctor Who: The Doctor is the last survivor of Gallifrey, who reincarnated various times. In his/her past lives he/she has been Rowlf, Optimus Prime, Shaggy Rogers, John Crichton, Kevin Mask, Rango, Captain Harlock and Stanley.
- As Kevin, he travelled with Ginger, Katara, and Martha Kent.
- Don't Trust the B---- in Apartment 23: Film!Sailor Venus tries to scam Film!Chibiusa.
- Drake & Josh: Sasuke and Naruto become step-brothers.
- Family Matters: A show about Earl Sinclair's family but especially their annoying neighbor...Lisa Simpson. Lisa is madly in love with one of the daughters named Heloise who doesn't love her back. Later Lisa finds herself in a love triangle between Heloise, her unrequited crush, and Meg Griffin, a perky nerdy girl obsessed with her.
- Firefly: Will Truman, Xenophilius Lovegood, Pocahontas, Sassy, Galadriel, and Prince Gumball are space outlaws.
- "Jaynestown": Magistrate Higgins gets Bree van der Kamp to sleep with his son Fess; Lovegood has a ballad and a statue dedicated to him.
- The Fresh Prince of Bel-Air: Ed is a teenager who is sent to live in Bel Air with his aunt and uncle, respectively Zelda Spellman and Willard Kraft (the former was once Sister Mary Claire), his cousins Tyrion Lannister, Smurfette and Rory Gilmore, and the butler Frank Reynolds.
- Friends: Hermes Conrad, Littlefoot, Julia, Dot Matrix, Geordi LaForge, and Yogi Bear are friends in their 20s.
- Joey: Geordi goes to Los Angeles for fame. Lara Croft is his Love Interest, Alex Munday is his sister, Kyon is his brother, and Wanda is his manager.
- Fringe: Fry has to meet up with his Mad Scientist dad Rex to solve sci-fi mysteries and they must save Chef's (later Conrad Fleem) dimension.
- Glee: Lois Lane is a cheerleading coach. Korra and Sportacus might be lovers. Substitute teacher Pepper Potts is a country singer. Chloe later dates Captain Planet. Season Five starts off with a tribute to star quarterback Brad Buttowski.
- Goosebumps (1995): Cell narrates the horror experiences of various children and teenagers; Omi, Scarecrow, Jubilee, and Odd are present in every episode.
- Welcome to Camp Nightmare: After a wave of freak attacks at camp, Omi suspects he's the next victim. Terry MacGinnis is the camer who never was.
- The Girl who Cried Monster: Brittany Taylor finds that the librarian is a monster.
- Phantom Auditorium: Omi and Fin suspect that a ghost is sabotaging the school play.
- Piano Lessons Can Be Murder: Gohan is a piano teacher who steals his students' hands. Blackarachnia better watch out!
- Stay Out of the Basement: Princess Celestia and Mac find their father Blitzwing's plant experiments.
- It Came from Beneath the Sink!: The sponge under Agent Honeydew's sink is really a monster that lives on bad luck.
- Perfect School: Scarecrow attends a boarding school where the students are cloned.
- Gossip Girl: The life and times of Upper East Siders Wasp, Penny, Jim Levenstein, Agent Smith, Ben Tennyson, and Mikey (who got Put on a Bus along with Roberta and Wasp's brother Oliver Oken). They are observed and linked by the title character/blogger Amélie. Wasp's parents are Mrs. Russo and Jack Bauer; the former later married Jack Frost. Jim and Mikey's rock star father is Cyclops. Agent Smith once dated Giselle. Noah hates Jim and Smith. Wubbzy isn't really Wasp's cousin. Dawn Summers is an Alpha Bitch. Belle is not Ben's mother. Lizzie McGuire is a movie star. It turns out Jim is the Gossip Girl; Amelie returns for the finale.
- Henry Danger: Steven Universe is the sidekick of Eugene Fitzherbert.
- Heroes: Wile E. Coyote has the power of flight, and his little brother can absorb others' powers. The younger brother's mentor is Agent Mulder, and his niece is the indestructible Beth Cooper, whose adopted father Truman is caught up in a conspiracy; her genetic mother Jing-Mei Chen is a mental fire-starter. Beth only trusts Spider-Man concerning her powers, and her roommate Roxy Richter is in love with her. Daggett is a psychotic watchmaker who is the son of Martha Logan. Earl is a mindreader. Turk can bend the time space continuum; his father is Razoul. Later Turk's friend Jocktopus can supercharge others' powers; Turk's Love Interest Trillian remembers everything. Where there's Mulder, Scully lucked out by having super-strength, ice powers, and becoming her own twin. Scully's husband Spike walks through walls. Liz Sherman lets one see trough her own eyes. Bender is a healer. Castle is a godly 400-year-old. Veronica Mars can shoot lightning from her hands, and her father is Private. Roger can manipulate the earth. Sasuke Uchiha earns enhanced strength, agility and reflexes after injecting himself with a gene-altering formula.
- Home Improvement: MacGyver (later Marty McFly) is a family man.
- House: Riker (later Fire Lord Ozai) is a diagnostic doctor.
- How I Met Your Mother: The year is 2030. Kratos tells his kids Sari Sumdac and Deidara how he met their mom (she isn't Misty or Athena).
- Back in the present, Kratos (then Yuma), Sailor Moon, SpongeBob SquarePants, Vegeta, and Madame Foster have adventures.
- I'm in the Band: Lion-O becomes the guitarist for Iron Weasel, alongside lead singer Commissioner Gordon, bassist Klaus, and drummer Hermes Conrad.
- It's Always Sunny in Philadelphia: The story of a group of depraved friends including Clark Kent, his twin sister Kate, Dipsy, and Screech. Later they are joined by the twins' father Geoffrey.
- Kirby Buckets: Junior wants to become a famous cartoonist like his father Dwayne. Junior and his best friends, Carl Grimes and Ricky Harper, go on amazing adventures as his drawings come to life.
- Level Up: Shinji Ikari, Katniss Everdeen, Peeta Mellark, and Tripp Campbell fight real-life video game characters, with help from video game developer Kevin Levin.
- Lois & Clark: John Winchester (later Cleveland Brown) and Steve Urkel work at a newspaper.
- (seasons 2-4) Luke Skywalker is the man of Steel, and Galadriel is his co-worker/love interest.
- Lost: Harmon Rabb becomes leader of a group of plane crash survivors, including Cleopatra, Lelouch, and Jack Sparrow. Nathan Petrelli doesn't age.
- Malcolm in the Middle: Peg Bundy and Maverick raise four dysfunctional children, with Stifler, who is sent to military school, as the eldest. Dot/Finch's best friend in a wheelchair is Scaredy Squirrel.
- (seasons 1-5) Peg and Maverick raise three daughters: Hello Kitty, Dot Warner, and Pearl.
- (seasons 6-7) Dot is now Finch; Kitty becomes Kyle XY; and Pearl transforms to Jimmy.
- Married... with Children: B.A. Baracus marries Leela and they have two kids: Kenan and Sophie.
- Nacho Libre: Dipsy becomes a Mexican wrestler.
- The Nanny: Spot Chicken meets a rich producer named Popeye and becomes the nanny for his children Fred, Ariel and Hortensia. In this show, Eustace and Muriel Bagge actually met for the first time, the former being the butler and the latter being Popeye's rich and snobby business partner.
- NCIS: Tony Stark is the gruff head of a group of Naval Detectives, with Will Brandt as his Second-In-Command.
- Ned's Declassified School Survival Guide: Mac writes a school survival guide. His two best friends are Lee Syaoran (Blurr in the Nickelodeon dub) and the Wii Fit Trainer.
- No Ordinary Family: Hank Hill, Velma Kelly, Shane Botwin, and Hermione Granger receive superpowers.
- Out of Jimmy's Head: After an accident, Dash gets a brain transplant and starts to see cartoons around him, like Monkey D. Luffy, Salty Mike, Yumi and Eduardo. Buzz, son of the original owner of Dash's new brain, wants it back. Dash loves Nurse Joy, sister of his best friend Flapjack. Dash is also Truffles and Baxter Stockman's son, and Rarity is his alien sister.
- Party of Five: Following the death of their parents, Duncan becomes the de-facto parent of his siblings Uhura, Rika, and Doogie Howser, M.D. (the latter of whom is dating Taylor Hagan).
- Power Rangers: The rangers for each series are as follows...
- Mighty Morphin' Power Rangers: Dib, Todd, Terry McGinnis, Montana Max, Kanchome, Orochimaru, Waldo, Cyclops, Princess Clara, and Penny.
- Power Rangers Zeo: Dib, Orochimaru, Waldo, Cyclops, Penny and Luke Triton.
- Power Rangers Turbo: Dib, Cyclops, Nadeshiko, Orochimaru (who became Masquerade), Penny and Wrath.
- Power Rangers in Space: Mr. Popo, Usopp, Lina Inverse, Kaito Kid and Sailor Uranus.
- Power Rangers Lost Galaxy: Geronimo Stilton, Sousuke Sagara, Starscream, Mai Valentine, Batgirl and Minx.
- Power Rangers Lightspeed Rescue: Dawson Leery, Soul Eater, Spider-Man, Kokujo, Dawn Summers and Princess Bubblegum.
- Power Rangers Time Force: Fred, Martin Mystery, Beth, Malcolm, and Jack Sparrow.
- Power Rangers Wild Force: Kamina, Faye Valentine, May Kanker, Trevor Troublemeyer, Milhouse and Dr. Hamsterviel.
- Power Rangers Ninja Storm: The Fallen, Kim Possible, Ma-Ti, Kick Buttowski, Thomas & Friends and Doug.
- Power Rangers: Dino Thunder: Masquerade (now Billy), Ashley Spinelli, L, Kit Cloudkicker and Kyon.
- Power Rangers S.P.D.: Jamie, Willy Wonka, Meg Griffin, Sokka, Suzy Chan, Buford and Monterey Jack.
- Power Rangers Mystic Force: Elmer Fudd, Cosmo, Frodo, Rhonda, Kid Muscle, Dave Seville and Anna Williams.
- Power Rangers Operation Overdrive: Danny Phantom, Dave the Barbarian, Sheldon, Excel, Ms. Marvel and Jaller.
- Power Rangers Jungle Fury: Hawkeye, Superman, Ryuji Takasu and Kagome.
- Power Rangers RPM: Bumblebee, Bren, Daphne, Applejack, Braeburn, Ash Ketchum and Renji.
- Power Rangers Samurai: Waddle Doo, Miko, Kyubey, Nick, Ezio Auditore and Freddie Benson.
- Power Rangers Megaforce: Nightcrawler, Blue Beetle, Tadashi Karino, Aika S. Granchezsta and Lily Valley.
- Pretty Little Liars: The lives of four friends, Bloom, Sharpay Evans, Ugly Betty and Claire Bennet after the disappearance of their leader Tawni.
- Sabrina the Teenage Witch: Wednesday Addams is a teenage witch who lives with her aunts Cristal Connors and Ronnie Cooke and pet cat Budge.
- Sex and the City: Izzy, Tricia Takanawa, Princess Kida, and Spider-Woman are 4 fashion-obsessed women.
- Smallville: Eric is a teenage man of steel.
- The Suite Life of Zack & Cody: Maui runs a hotel, where he deals with the antics of the wealthy airhead Luisa Madrigal and the candy counter Jetybory.
- Supergirl (2015): Miles is a teenage girl of steel. When she isn't fighting crime, she works at Fujiko Mine's newspaper alongside Spyro and Dean Winchester. Joy is Miles' adopted sister, and Li Shan works for the government.
- Supernatural: Edward and Jacob are now brothers, fighting monsters while searching for their father the Hulk. Edward later gets raised from perdition by the angel Harmon Rabb.
- One Tree Hill: Edward and Jacob are together again, this time as half-brothers and basketball players! Now Bella is only in love with Jacob and marries him before the end of season 1. Meanwhile Edward (Bella's childhood best friend) is involved in a love triangle between Judy and Peter Shepherd (his longtime crush).
- Tabatha Takes Over: Ophanimon gives failing places a makeover, in hopes of surviving.
- Teletubbies: Turk (later Wash), Bartok, Laa-Laa, and Po have adventures in Teletubbyland. Narrated by Conan the Barbarian.
- That '70s Show: Swiper is growing up in 1970s Wisconsin, often hanging out with Chaz Finster, Kelso, Amy Farrah Fowler, Izzy, and Chum-Chum. Swiper's father is Pops.
- 3rd Rock from the Sun: Hector Con Carne, Batman, Sally, and Keitaro are a family of surprisingly human-looking aliens. Phyllis is a professor. The aliens' boss is Captain Kirk.
- Two and a Half Men: Wreck-It Ralph leaves after season 8, with Zuko moving in.
- Unbreakable Kimmy Schmidt: Blair Waldorf, Carrie, Peggy Olsen, and Carmen spent their teens and twenties in BoJack Horseman's doomsday cult. After they are freed, Blair instantly moves to New York City, where she moves in with Chuck and hires Arwen as her maid. Mrs. Bird is Blair's landlady.
- The Vampire Diaries: London Tipton is a girl who lives with her aunt Cersei and her younger brother Harry Potter. She begins a relationship with a vampire obviously named Edward Cullen, but later Edward's older brother Xander also falls in love with her. London's best friend is a witch named Serena van der Woodsen, but she's also good friends with Bernadette Rostenkowski. London later learns that Jack Sparrow is her father.
- Weeds: Phineas wants to become a drug dealer like his mom the Fairy Godmother.
- Wizards of Waverly Place: Private and Wanda arrive in San Francisco with their kids: Yin, Jake, and K.C. Guthrie. They're wizards!
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