In both the novel and movie of High Fidelity, Rob, Barry and Dick go to see Marie LaSalle plays, and when she plays "Baby, I Love Your Way", they end up loving it, even though they normally can't stand Frampton (it helps all of them are attracted to her).
In One-Trick Pony, a record executive says that Peter Frampton is more spectacle than music.
Reality Bites: A cover version of "Baby, I Love Your Way" plays when Leilana and Michael are making out in his car. When Leilana comes into her apartment, Troy sings it derisively to her.
The enormous popularity of Frampton Comes Alive was referenced in Wayne's World 2. Wayne's girlfriend, Cassandra, had found a copy of the album at a garage sale.
SpongeBob SquarePants: In "Atlantis SquarePantis", Patchy the Pirate is shown to own an ultra-rare 8-track of Frampton Comes Alive!, but it ends up getting destroyed when he puts it into his car radio.
