Reality Bites: When Leilana and Vicki are at a diner, Vicki talks about how afraid she is of catching AIDS (since she Really Gets Around), and sees herself as being a character on Melrose Place, teaching people it's okay to be near her even if she has AIDS. Leilana tells her not to freak out, and she'll help Vicki get through it. She then adds, "Melrose Place is a really good show", which Vicki laughs at.
Seinfeld: "The Beard" has a girlfriend of Jerry's trying to get him to admit that he likes the show over his repeated denials before he finally breaks down after a lie detector test reveals his love for the show. Throughout the show, he comes to realize that the rest of the gang loves it too, and the final scene has them sitting on his couch bopping to the theme music.
Animaniacs (2020) referenced the show during their song about reboots.
The first couple of seasons of Daria had their bumpers parody the Melrose Place bumpers (right down to the slow-motion shot). This may or at not have inspired the show to retire its usage in the final season.
"Krusty Gets Kancelled" has Krusty auditioning for the show.
In "Mother Simpson" after learning Mona Simpson is still alive and on the run from the cops, Lisa mentions that such a thing is "something out of Dickens, or Melrose Place".
In the "Simpsons Spin-Off Spectacular", it, The Simpsons and The X Files are one of three shows that appear on the Fox programming schedule.
has them sitting on his couch bopping to the theme music.