- Liar Liar: Fire Marshal Bill makes a cameo at the end of the film.
- The Fresh Prince of Bel-Air: an episode of the show has Will doing an impression of Keenan Ivory Wayans and introducing his "Fly Girl" Ashley.
- Designing Women: One episode has Bernice saying, "Homey don't play that!"
- The Chris Rock Show: Chris' character from season five of In Living Color, Cheap Pete, appears in a few episode.
- Saturday Night Live: an episode hosted by Damon Wayans features a Men on... sketch which reunites him with David Alan Grier.
- On the premiere episode of Behind the Music featuring the story of Milli Vanilli, one moment has Fabrice Morvan talking about the time he and Rob Pilatus viewed the "Milli Vanilli Do It Yourself Kit" sketch on the show, which also aired a few clips of said sketch.
Music
- The music video for Bruno Mars' "Finesse" featuring Cardi B pays homage to the first two seasons' intros, the set and the Fly Guys.
Professional Wrestling
- On the his official YouTube page, Jim Cornette has two different podcasts with the animated title cards of him dressed as Fire Marshall Bill and he and Tony Khan as Blaine Edwards and Antoine Merriweather, respectively.
- Homey D. Clown was a 1993 Arcade and PC game based off of the popular skit.
- The Cinema Snob: In his review of the infamous 1989 Wired film, the Snob remarks how the weird poses of John Belushi (played by Michael Chiklis) while performing Joe Cocker's "You Are So Beautiful" was reminiscent to the Handi-Man character from the show.
- How It Should Have Ended: In "How Sonic the Hedgehog Should Have Ended", Robotnik summons an army of robots based on various characters that Jim Carrey has played over the years, including Fire Marshall Bill and Vera de Milo. The former is set on fire by Blaze the Cat, while the latter is beaten by Knuckles the Echidna.
- Tiny Toon Adventures: One episode has Babs trying in vain to find "that cute thing she does" to impress her mother, one of which is an impression of Homey D. Clown.
- The Simpsons:
- In "Bart Gets Famous", a segment of Krusty the Clown's show has the "I Didn't Do it" Dancers, who are clearly based off of the Fly Girls.
- While teaching a dance funk for self-defense class in "Secrets to a Successful Marriage", Moe states to the class "Say some gangsta is dissing your fly girl."
- The episode "Homie the Clown" was named after the character.
