Shaun's unique ability to relate to a patient isolated by an immune deficiency yields an unexpected result. Claire, Morgan and Andrews treat a 12-year-old patient who is about to become blind. Tension builds between Melendez and Lim.
- Bubble Boy: One of the Patients of the Week has weak immune system, forcing her to live in a bubble.
- Continuity Nod: Melendez is still heartbroken over losing his patient in the last episode and it gets him into a conflict with Park over trying a risky treatment for their next patient and adamantly refuses to even present the option to the patient.
- Dirty Kid: One Patient of the Week is a 12-year-old kid who's about to go blind, and one of his last wishes before is to see a naked woman. Morgan and Claire actually try to take him to a strip club, but the bouncer refuses to let him in. So Morgan just decides to flash him herself instead.
- Littlest Cancer Patient: Played With. A Patient of the Week is a child who is about to become blind for life, and Morgan and Claire try their best to fulfill some of hi wishes of the last things he wants to see.
- No Social Skills: Shaun, as always. Lea warns him that it is good for him to respond to Carly's messages, even when it is not a question. Later, Shaun is unable to decipher an emoji he received from Carly and asks Lea for help.