Mission of Ruin was Teppen's twelfth expansion, and the first part of the "War of the Goddess" trilogy.
''Mission of Ruin" contains examples of:
- Brainwashed and Crazy: The Mind-Control Stones turn any and all things into slaves of Myria, be it man, machine, or monster.
- Elite Four: Myria has four characters serve as her "Guardians", giving them the same Control Ring and Evil Eye that Ada used in the character stories:
- Epsilon from Mega Man X: Command Mission
- Juno from Monster Hunter Explore
- Osmund Saddler from Resident Evil 4
- and Xavi from Sengoku Basara