This is based on opinion. Please don't list it on a work's trope example list.
"So this is what it's like to stare into the face of death."
- Kitty/Schrodinger's first appearance; the cat literally lunges at you to kill you...and that's just one of many jump scares in the game.
- Just look at the zombie in the page image... Cole is just looking through some lockers in the hope of finding something, with no weapons in hand, only to be met by that. The worst part? In order for him to have ever survived that encounter, he had to literally poke its eyes out in an effort to reach its brain, which still didn't impede it. Imagine how many players must have been horrified with this on their first encounter, not knowing what to do.
- Kane's family was having a birthday party when the outbreak first started. His family was all happy, celebrating his sister's special day, only for them all to be devoured by a horde of zombies. Even worse, there's a possibility that his family members have been reanimated as zombies, and are currently feasting on any other hapless people.
- Guol kills Kane by sealing him in a coffin-like apparatus and dissolving him with a flesh-eating gas...all while the poor guy's still alive and conscious, screaming in agony as his body melts. And you get to see all of it.