Like Shrek and Bee Movie after it, The Road to El Dorado is known for being highly quotable since its release in 2000.
- "The stars are not in position for this tribute!"
- "I am Miguel." "And I am Tulio." "And they call us Miguel and Tulio!"
- "Both?" "Both." "Both!" "Both is good."Explanation
- What really makes this is Tulio and Miguel nodding to each other at the end.
- GIFs of Miguel's intense lute playing◊ during the gambling scene are quite popular on Tumblr.
- "Tulio! The hip! The hip!"
- "...And then we row back to Spain!"
- "Ha, you fight like my sister!" "I fought your sister, that's a compliment."
- "On the one hand, gold! On the other hand, painful, agonizing failure!"Explanation
- Comparing the movie to Dungeons & Dragons by referring to it as "the bard and the rogue have their own adventure" and "a series of natural 1s and 20s", among others.
- The scene where Chief Tannabok gets news about the upcoming invasion has spawned numerous edits that replace the dialogue with something else, usually a copypasta.
- A similar meme exists using the scene where Miguel and Tulio lie to the Chief.