Self Destruct may refer to:
- The Action Bomb trope for characters who explode/self-destruct as an attack.
- The Self-Destruct Mechanism trope for something that turns into a bomb when necessary.
- The Self-Destructing Security trope for theft-prevention of an object by destroying it.
- The This Page Will Self-Destruct trope for a secret message, self-destructing after being delivered.
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