Quarantine may refer to:
- Quarantine: A 1992 Science Fiction novel, by Greg Egan.
- Quarantine: A 1994 Vehicular Combat video game, developed by Imagexcel.
- Quarantine: A 2008 Found Footage Horror Film, directed by John Erick Dowdle.
- Quarantine with Extreme Prejudice, the trope for a quarantining an infection that's so dangerous that lethal force is enacted to keep it from spreading.
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