Men in Black may refer to:
- The Men in Black, a trope about the stereotypical mysterious government agents in black suits.
- Men in Black, a science fiction franchise based on the above trope, including (but not limited to):
- Men in Black, the original comic book.
- Men in Black, the movie based on the comics, which led to some sequels.
- Men in Black: The Series, the cartoon series based on the movie.
- The Three Stooges' 1934 short film focused on the titular trio as doctors in a hospital.
- "The Man in Black", a nickname of Johnny Cash.