Aces & Eights may refer to:
- The trope of the Dead Man's Hand, a poker hand with two aces, two eights, and any other unmatched card. Usually a Death Signal.
- Aces and Eights: Shattered Frontiers, an Old West-themed tabletop RPG released in 2007 by Kenzer and Company.
- Aces & Eights (Wrestlers), an outlaw motorcycle gang featured in Total Nonstop Action Wrestling, which debuted in 2012.
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