The series initially focuses on four primary characters – Athena, Persephone, Aphrodite, and Artemis — as a diverse group of loyal friends. Athena is noted for her intelligence, Persephone is mysterious and kind, Artemis is bold and strong, and Aphrodite is "effortlessly beautiful". Joan Holub writes about Athena and Artemis, Suzanne Williams about Persephone and Aphrodite. Later books in the series expand the roster to include many more goddesses, plus the occasional demigoddess or mortal.
Zeus is represented as the Principal of the Academy, and many other gods, including Hades, Poseidon, and Ares, appear in the series while Pandora, Medusa and Heracles appear as mortal characters in the series. The series includes deities and characters from other mythological traditions as visitors to the Academy.
The books in the series are:
- Athena the Brain
- Persephone the Phony
- Aphrodite the Beauty
- Artemis the Brave
- Athena the Wise
- Aphrodite the Diva
- Artemis the Loyal
- Medusa the Mean
- The Girl Games (Super Special)
- Pandora the Curious
- Pheme the Gossip
- Persephone the Daring
- Cassandra the Lucky
- Athena the Proud
- Iris the Colorful
- Aphrodite the Fair
- Medusa the Rich
- Amphitrite the Bubbly
- Hestia the Invisible
- Echo the Copycat
- Calliope the Muse
- Pallas the Pal
- Nyx the Mysterious
- Medea the Enchantress
- Eos the Lighthearted
- Clotho the Fate
- Persephone the Grateful
- Hecate the Witch
- Artemis the Hero
- Elpis the Hopeful
This series provides examples of:
- Abusive Parents: Ceto and Phorcys, Medusa’s parents, seem to prefer her sisters over her, plan to sell her things while she's away at MOA and make her sleep in a walk in closet.
- Why exactly did Zeus leave Athena to be raised on Earth, exactly? And why is this never brought up?
- Action Girl: All the main Goddess Girls have their moments but Artemis is the leading lady.
- Age Lift: A great many of the Greek Gods receive this treatment. Justified, since the primary setting of the story is an elementary school.
- Beauty, Brains, and Brawn: Aphrodite is the Beauty, Athena is the Brain and Artemis is the Brawn.
- Beware the Nice Ones: All four of them, especially Persephone.
- Big Sister Bully: Stheno and Eurayle towards Medusa.
- Blonde, Brunette, Redhead: Aphrodite is the Blonde, Athena and Artemis are Brunettes and Persephone is the Redhead.
- Genki Girl: Iris and Eurydice.
- Jerkass: Orion.
- Jerk with a Heart of Gold: Medusa, as of Medusa the Mean and Poseidon as of Amphitrite the Bubbly
- Lighter and Softer: A version of Greek Mythology that's made for elementary schoolers, so this is a given
- Nice Job Breaking It, Hero: All girls have their moments: Athena accidentally sends a storm of inventions down to Earth, Persephone runs away from home after a fight with her mother and friends, Artemis breaks the Hero-ology statue and Aphrodite starts freaking war! Pheme notes three of them in Pheme the Gossip.
- Tomboy and Girly Girl: Aphrodite’s Girly Girl to Artemis’ Tomboy.
- Tsundere: Persephone is a Type B.
- Unrelated in the Adaptation: Holub and Williams removed several blood relations between the Greek Gods. The biggest example is Athena being not related to Artemis, Heracles and Dionysus, who would be her siblings had the books been more faithful to Classical Mythology. In the same vein, not only is Poseidon and Hades much younger than Zeus here, there's no indication whatsoever about the three being brothers.
- Why Did It Have to Be Snakes?: Poseidon admits to Athena his fear of snakes in the first book. This is brought up again in Medusa the Mean. Ironic, given his original relationship with her.