Two best friends fighting, but still care for each other.
- Alex and Harper◊ from Wizards of Waverly Place.
- Chew: Chu and Colby◊
- Cable and Deadpool◊.
- Cures Rouge and Aqua◊ from Yes! Pretty Cure 5.
- X-Men: Emma Frost to Kitty Pryde◊ and Storm◊.
- Justice League Unlimited:
- Homer and Ned◊ from The Simpsons.
- Kallen and C.C.◊ from Code Geass.
- Kenan & Kel in the house◊.
- Sam and Freddie◊ from iCarly.
- Skwisgaar and Toki from Metalocalypse.
- Statler and Waldorf◊ from The Muppet Show.