- From Bleach: Kukaku Shiba.◊
- How to Train Your Dragon: Hiccup and Toothless.◊
- Brave: Fergus.◊
- Spider-Man: Across the Spider-Verse: Charlotte Webber aka Sun Spider
- Django: Django
- Star Wars:
- Anakin Skywalker as a Jedi◊ and Darth Vader.◊
- Luke Skywalker.◊
- From Discworld: Mad Hamish.◊
- Professor X from Marvel Ultimate Alliance.
- The Dr. Timothy card◊ from South Park: Phone Destroyer.
- Avatar: The Last Airbender: Toph Beifong.
- The Legend of Korra: Ming Hua.◊
- Samurai Jack: The Scotsman.◊
- The Dragon Prince: Amaya◊ (she's deaf).
Other
- This post compiling a number of handicapped and/or neurodivergent badasses from different forms of media.