The Danganronpa series often shows moments of friendship and love between students as people start dying around them, and An Adventure of Mutual Despair is no different.
- When the poison motive kicks in, Tamaya stays by a terminally ill Sentoki to keep her comfortable, not moving to eat or sleep until someone orders her to. That's loyalty.
- Sentoki draws a picture of all of the students smiling together, labeling everyone as her 'Best Friends'. Yes, even the ones that lied to her and those that murdered their fellow students.