In 10, you might have noticed that Ninja's eyes are now blue instead of brown. If you don't bother check it because this Ninja's change is too sudden, then 11 reverts his design back to the one we're familiar with, but still with blue eyes. So why is this change worth attention? Aya, his Kohai, also has blue eyes. This change is apparently made to further emphasize their relationship, even though it's currently uncertain if Aya will ever return again.
Despite saying that it puts opponents to sleep, the Hibernation card freezes the opponents in 4 and Online (and even then Online's Hibernation card icon is a bottle of sleeping drug) instead of making them fall asleep like in all other games. Well, it technically still is hibernation, as the characters are turned into Human Popsicle, also known as hibernation or cold sleep.
Retcon might be in effect for this one, but when you think about how Yao has stated that October is based on his own grandfather, then his design in 4 and 5 as an alien makes much more sense: he isn't just a random alien, he is Doctor Y's grandfather!
King Octopus can disguise as many characters and it takes a while for James and Coolva to find him out. Real life octopi are indeed known as being good at disguising.
Nuclear missiles can remove the ownership of properties as well, reverting anything and everything back to an empty field. Real life nuclear missiles will really vaporize everything in its ground zero, although a nuclear missile that is larger than the regular missiles in size will definitely wipe out an entire map and all people on it in reality.
Although it's really just one of his dialogues and won't apply to gameplay, there's something that's scarier when you think about it. King Octopus says that he can blow up the hospital with "two presses", which means that he probably has set bombs in the hospital, and not only can he escape hospitalization by bombing it, he can also potentially kill his enemies with the same bombs when he is hospitalized.
