The LOG toy from Blammo, which only existed as a fake commercial in-universe, eventually did become a real Ren and Stimpy related toy.
John Kricfalusi noted on the DVD commentary for Sven Hoek that there is or was a website dedicated to the Loyal Order of Stupids, Sven and Stimpy's "club" in that episode.
Kim Possible - Purely unintentional...probably, but there has been a great deal of positive response to Taco Bell's new Beefy Nacho Burrito because after ten years they finally caved and made a real life Naco.
Metalocalypse - Dethklok released an album in 2006 The Dethalbum, which according to Billboard is the biggest selling death metal album of all time and followed it with a brief tour as opening act for the indie rock band And You Will Know Us By The Trail of Dead, and later a headlining tour in 2008.
Now you too can be strong to the finish with Popeye's brand spinach◊. At least it doesn't come with taurine in it.
Real versions of Cheesy Poofs and Chef's Chocolate Salty Balls appeared early in the flood of the show's merchandise. The Cheesy Poofs were notably sold in movie theaters to help promote the movie, and came back for a spell in 2011.
A Guitar Hero arcade machine was released about a year or two after "Guitar Queer-o" aired. Cartman played Poker Face on Rock Band, which wasn't actually available until later. You can tell this defictionalization was a response to the scene in question since there is also a Cartman version.
As of December 2016, you can now buy replicas of Stan's, Kyle's, Cartman's, and Kenny's hats.
Butters mentioned playing a game called Hello Kitty Island Adventure in a 2006 episode, which didn't exist back then. However, it now does, and it's a life sim for IoS phones.
Burger King released a Krabby Patty to tie in with The Movie, only with beef patties instead of imitation crabmeat patties. There are also the candy Gummy Krabby Patties from Frankford Candy.
Squidward's painting "Bold and Brash", from the episode Artist Unknown, is often imitated by real life painters and can even be bought online on Amazon. Ironic, considering that, in-universe, the art critic that evaluated "Bold and Brash" said that it 'belongs in the trash'.
A company called Salta Burgers constructed a real-life Krusty Krab which opened in Ramallah, Palestine/Israel on July 24, 2014, replicating the arch-shaped exterior◊ and the interior◊ with meticulous accuracy.
The pirate painting from the beginning of the show's theme song is an actual item sold at Hot Topic.
Nick.com posted an official Krabby Patty recipe, which has since been spread around the internet on places like Reddit.
Someone actually made a real life version of the board game Patrick invented in the episode Patrick! The Game which you can see here.
Some of the board games seen on the show (Flying Dutchman's Treasure Hunt from "Arrgh!" and Eels and Escalators from "Sailor Mouth") are sold as Hot Topic exclusives.
A number of Scooby-Doo fans have also decorated their vans into the Mystery Machine livery.
In a strange sort of semi-example, the Transformers: Animated version of Soundwave is essentially a Scion xB with Serial Numbers Filed Off — more streamlined and slightly more futurey. The Scion xB was redesigned... and it looks like Soundwave.
Goodwood's Junior Festival of Speed has defictionalized all eleven vehicles from Wacky Races into full sized working cars. They also have people dressed as the drivers of each vehicle (characters like Muttley and Sawtooth get full body costumes).
This Peugeot commercial from Italy takes it further and has the racers in human flesh and blood forms.
The Dungeons & Dragons (1983) cartoon introduced several character classes (such as the cavalier, the barbarian, and the acrobat) that were not part of the AD&D rules at the time. Naturally, they were added in a later revision.
The "Card Wars" Collectible Card Game from the titular episode has been adapted into an actual game, both in physical and iOS/Android video game formats.
Moosylvania from Rocky and Bullwinkle nearly became the name of a small state next to Minnesota. The "Moosylvania for Statehood" campaign was cut short when the petition reached the White House just as the Cuban Missile Crisis was unfolding.
In August 2010, a number of Disney Stores across America held events where kids could make their own Perry the Platypus Inaction Figure, like the ones from the Phineas and Ferb episode "Toy to the World".
Speaking of which, a pretty good amount of fans have tried to create Ducky Momo stuffed animals modeled after Candace's own Ducky Momo. And some people were lucky enough to receive an actual plate based off of the one where they accidentally printed "I Hate People".
The My Little Pony: Friendship Is Magic episode "Lesson Zero" featured a stuffed doll called "Ms. Smartypants". A real-life version was completed within 7 hours of the episode's airing. Not to mention that many fans have gone out of their way to make their own version of toys and plush to be more consistent with the show than the actual products offered by Hasbro.
The fans go so far as to try out various recipes on the show, which range from the baked bads from "Applebuck Season", to the surprisingly appetizing Chimmicherrychangas from "The Last Roundup".
And, after the Daring Do page got popular, some bronies decided to start defictionalizing the core books, based on the (actually quite detailed) page.
Not to mention the Discord lamp from "Keep Calm and Flutter On", the lead-pony and wingpony badges from "Wonderbolt Academy", the Reference Guide to the Elements of Harmony, the Alicorn Amulet and Element of Harmony necklaces...
On the official merchandise side of things, we have Daring Do books (by G.M. Berrow under the alias A.K. Yearling, to boot) as well as Celestia and Luna's journal seen in "Castle Mane-ia".
Czech brony musician Tommy Scraton has given himself the artist name DJ Pon-3.
Someone defictionalized the unicorn horn disabler/changeling detector from "Equestria Games". It appeared at the 2014 BronyCAN convention, where it was auctioned off for 200 dollars.
The eponymous character in the children's show Theodore Tugboat lives in a fictionalized version of Halifax, Nova Scotia, Canada. Since 2000, visitors to the real-life Halifax have been able to take a harbour tour aboard Theodore Too, a full-scale replica of the character.
The Disney Wartime CartoonVictory Through Air Power showed a rocket-assisted bomb punch through a German submarine pen's roof and detonate inside, before such a bomb existed.
There are replicas of Dora's backpack available for purchase.
Speaking of backpacks, Cartoon Network is selling an official cheeseburger backpack like that worn by one Steven Universe.
Steven's iconic star T-shirt is also officially available, as is the Guitar Dad shirt from "Shirt Club" and the hot dog duffel bag from the short "Novelty Backpack".
On a less official note, some fans have made it their mission to recreate some of the more outlandish food products from the show, like the Dog-Nut and an "everything" pizza.
Cartoon Network is also selling a replica of Steven’s iconic varsity jacket from the movie and Future.
After many unofficial replicas sold online, Disney gave the rights to online retailer We Love Finenote (now known as For Fans By Fans) to sell an official replica of Dipper's hat for a short period of time.
The Mystery Shack sells Dipper's original hat, two alternate replicas of Dipper's pine tree hat, Mabel's shooting star sweater, Mabel's pink heart hat from "Soos and the Real Girl", Stan's fez, Soos' Mystery Shack staff t-shirt, Soos' Pterodactyl Bros. t-shirt, Pizza Guy's Free Pizza t-shirt, Cool Stump t-shirt, What is the Mystery Shack? bumper stickers, Mr. Mystery Bobbleheads, and copies of the iconic Journal 3note (including briefly selling some copies of the special blacklight edition during the initial release.).
The centerpiece of the series, the Author's Journal 3, was released as a book a few months after the series finale, with a special edition versionnote only 10,000 copies were made that more closely resembled the in-series book (pages are made of parchment, black-light hidden messages, a magnifying glass, etc.) being sold almost a year after the show ended.
A blog dedicated to recreating the daily special burger recipes from Bob's Burgers.
Every iteration of the Omnitrix has been available as a toy that can be bought from the Bandai online store.
Several replicas of Thomas & Friends operate around the world, mostly at official events known as A Day Out with Thomas. Replicas of Toby the Tram and (non-functioning) Percy also exist. Similarly, locomotives at the Talyllyn Railway in Wales are often painted to resemble their "twins" at the Skarloey Railway.
Also unintentionally invoked when Doc Mcstuffins plushes were released, since Lambie, Stuffy, Chilly and Hallie are plushes in the show to begin with, and at that, regular inanimate plushes brought to life with a magical MacGuffin.
"Yogi Bear's Jellystone Park Camp Resorts" are a real-life franchise of campgrounds based on Jellystone National Park from Yogi Bear.
Over the Garden Wall: Mondo Tees had a limited release of the cassette tape Wirt made for Sara. More recently, Hot Topic carries a variation of Wirt's cape, complete with an attached red hood that evokes his conical hat.
Foods from We Bare Bears are also being brought to life.
Rick and Morty: The collector's shop FYE Sells Strawberry Smiggles, the fictional cereal from the episode "Rixty Minutes" (though whether or not making a food product based on such a squicky scene is a good idea is debatable). There'a also real plumbuses you can buy.
For a limited time in 2017, the Reptar Bars and Reptar Cereal from Rugrats were sold at FYE and Suncoast. And yes, the Reptar bars do in fact turn your tongue green, though they sadly aren't actually shaped liked Reptar, nor do they contain caramel or nuts. FYE's Reptar Cereal is merely a Froot Loops clone, a far cry from the version seen in the show ("They're round, they're mean, they turn milk green!").
A Deluxe Reptar Bar, which more closely resembles the version seen in the show, is now available from FYE as of October 2018, as well as a "Reptar on Ice" bar that turns your tongue blue.
In the Animaniacs episode "Lookit the Fuzzy Heads", the Warners have their own puppets in their likeness that are used during a therapy session. Dakin made them into actual toys a few months after the episode aired.
Cartoon Cuisine has the blogger make food that is seen in various cartoons.
The Epic Tales of Captain Underpants: George and Harold's Epic Comix Collection features all the comics made during the first two seasons of the show.
DuckTales (2017) features an in-universe example with Darkwing Duck. Rather than being an actual superhero, he's just the main character of a TV show that Launchpad used to watch as a kid. But when plans for a Darker and Edgier reboot movie fall through, he inspires the actor hired for the role to become a superhero for real.
The signature cars of Postman Pat and Noddy have been made into real-life vehicles.
For Noddy, Toyland Detective, the WhoWhatWhere Pad Noddy uses to solve mysteries was made into a real toy.
PAW Patrol: Ryder's motorcycle, Chase's police car, Marshall's firetruck and Skye's airplane were all made into ride-on toys for kids.
In a similar vein to the above, the vehicles in PJ Masks also have ride-on versions. There's also kid-sized versions of the trio's costumes and a PJ Robot toy.
During the original run of Blue's Clues, real life versions of the Handy Dandy Notebook and the Thinking Chair were produced. The sequel series also had those items made for it, as well as a real-life version of Josh's shirt.