Being a universe formed from two separate long-running comic continuities and several new ones, the Hasbro Comic Universe by its nature has numerous characters.
- Transformers
- The Transformers: More than Meets the Eye (including the crew of the Lost Light, former crew, the Scavengers, and the Decepticon Justice Division)
- The Transformers: Robots in Disguise (including the Cybertronian and Earthbound Autobots and Decepticons)
- The Transformers: Till All Are One (including Windblade and her allies, Starscream and his underlings, and the various Cybertronian colonists)
- The Transformers: Last Stand of the Wreckers (including the Wreckers, their allies, Overlord's Decepticons, and Mayhem)
- G.I. Joe (IDW) (including G.I. Joe, Cobra, and the Adventure Team)
- Action Man (including the Action Man Programme, Doctor X's operatives, and the Red Shadows)
- Jem and the Holograms (IDW) (including the Holograms, the Misfits, and the Stingers)
