Being a Massively Multiplayer Crossover, Blood and Revolution naturally has tons of characters. This list divides them into their respective factions.
- Kenshin's Clan note Kenshin, Hiko, Kenji, Atem, Yuugi, Jounouchi, Rei, Ryuuhou, Momiji
- Aoshi's People note Aoshi, Kaji, Gojyo, Hakkai, Seri, Ruby, Duo
- Bakurae note Bakura, Yukito, Ryou, Yue, the babies
- KaibaCorp note Seto, Seth, Mokuba, Integra, Alucard
- Youkai and Tsukumogami note Shun, Inuyasha, Sesshoumaru, Hana, Yoko no Kurama, Hyoga
- Kami and Gods note Rune & Tintlet, D, Kaworu, The Eathkami, Folken, Haru, Makoto, Demerei
- "Other" note Saitou, Abel, Touya, Shiroe, Pegasus
