Louis' first defining moment is where he barges into Butch, of Team Rocket, into a lake, and buying Taki and Totodile enough time to dispatch him and Cassidy.
Louis managing to scare off Gastly, Haunter, and Gengar after first learning he can talk to Pokémon, without a hint of fear.
This ends up being a small running gag in the story, with Louis messing with the Ghostly Trio.
Charla, Liza's Charizard, saving Louis from falling to his death in Charicific Valley
Pokémon: United Bonds:
Admit it. You smiled when Louis punched Simon in the face.