Played straight with L-Ron. In the comics, he's a sidekick to the Justice League International, while in the show he's Despero's assistant.
Geo-Force, a heroic member of The Outsiders in the comics, starts off more like his typical depiction from the comics as a hero. But in the season three finale, after learning he'd been Locked Out of the Loop of his sister Terra's nature as The Mole once she had a Heel–Face Turn out of being one, he turns against the other heroes and kills Baron Bedlam (their Evil Uncle in the show but not in the comics), breaking the no-killing rule in the process, and cements his Face–Heel Turn by usurping his twin brother Gregor (which is what Bedlam was trying to do) as the King of Markovia. Some of his actions may have been manipulated by Ambassador Zviad Baazovi, who had turned him into a Puppet King, but the ambassador stated that his psychic powers can only nudge people's inhibitions to the surface, suggesting Geo-Force might have wanted these things deep down.
Ma'alefa'ak initially appeared to be an example of Adaptational Heroism, reimagined as a Well-Intentioned Extremist, until through alliance with Apokolips, he attempted the genocide of his comics counterpart, even if the bomb he was given was not as successful as planned. Then he becomes a more openly loyal agent of Darkseid in the second half of season 4, showing he is actually a Not-So-Well-Intentioned Extremist, and even worse than his comic counterpart who at least kept his loyalties amongst criminals of Earth, using his talks of revolution to bait others who listen to his talks into being captured as prisoners of Apokolips. Then he becomes a participant of Lor-Zod's plans to free General Zod and their subsequent attempt to conquer Earth, making it clear he is doing this to spite his sister Miss Martian.
Lady Shiva is revealed to be Orphan's mother, and has also taken on the abusive traits of Cassandra's father David from the comics taken up a notch. David Cain in the main comics deliberately raised Cassandra without speaking to her or teaching her how to speak, making her learn how to read body language as her way of communication. Here, Lady Shiva did the same thing but first ensured Cassandra would stay mute by severing her vocal chords as a baby.
Mary Marvel, renamed Sergeant Marvel, starts off the same as her comic counterpart being Billy’s twin sister, but over the course of the fourth season continuously butts heads with her mentor in magic Zatanna and becomes increasingly Drunk with Power as a member of the Sentinels of Magic before eventually ditching the heroes and being easily corrupted by Granny Goodness, who persuaded Mary that her friends were envious of her power and leading to Mary becoming a Female Fury whom serves Darkseid.
Scandal Savage, Vandal Savage's daughter in the comics, often worked against her father due to his cruel treatment of her, though still largely an Anti-Hero. In the show, due to Vandal himself undergoing Adaptational Heroism, Cassandraremained loyal to her father as well as the League of Shadows, using slight grievances such as being abducted from her mother or watching her sister be killed to craft a cover story as a Fake Defector and stating she was proud she was taken by him.
Lor-Zod's changes in Superman Family Adventures and Superman (Rebirth) to make him more loyal to his father General Zod are adapted into the character, who is revealed to be the identity of the time traveler whose interference with a gene bomb was intended to assassinate Conner Kent, wanting to use his death to Ret-Gone the Legion of Super-Heroes out of revenge for them imprisoning his father. The fact that when Lor is finally introduced, he is shown to be loyal enough to Darkseid that his lieutenants can be instructed to serve him, produces possibly the evilest version of the character. He is eventually killed in the same explosionhe tried to kill Superboy with, however, as his mother Ursa is pregnant, it could lead to a second instance of this trope if she gives birth to a new Lor-Zod.
Season 4 also pulls this with Supergirl! of all people, as Kara was sent to Phantom Zone prior to Krypton’s destruction for unknown reasons before being taken out by the Light and handed over to Apokolips where she became one of Granny Goodness’s Furies alongside Mary. Her heroic and sweeter qualities are not present, not helped by the fact Miss Martian already had a lot of her personality.
Trajectory in the comics was a hero even when part of Lex Luthor's Infinity Inc, being killed by him disabling her powers. The show's version is with the comic team's original Token Evil Teammate, Everyman, in manipulating Geo-Force and being loyal to the Light.
