Galactus consumed Krypton in this story, and Brainiac helped him with it. Odin, telepathically feeling Krypton's destruction, sent his son Thor to Earth to be reborn, so that he could help defend Earth.
Captain America's last mission was stopping the Nazi's Project Ragnarok, in which Baron Zemo participated. The Howling Commandos collaborated with the Easy Company.
SHIELD detected the infant Kal-El's arrival on Earth and sent the Men in Black to investigate.
Grigori Rasputin (here a cultist of Trigon instead of the Ogdru Jahad) was responsible for bringing not one, but two children of Trigon into the world, Hellboy and Raven. For Raven's birth, he had the help of the Church of Blood, Baron Mordo, and Blackheart.
The Phantom Stranger was sent to recruit Steven Strange to be the Ancient One's apprentice.
The Spectre was the original Spirit of Vengeance, sent by God to punish the evil, before he went mad and started persecuting all magic users, forcing them to form the Statute of Secrecy. Now The Spectre is replaced by Ghost Rider, his chosen champion.
Thor grew up on Themyscira with Diana, until the Mask attacked.
Lex Luthor teamed up with The Kingpin and sent Jack Napier, Eel O'Brian and Flint Marko to sabotage Norman Osborn, who was trying to create super soldiers before him.
This act of sabotage led to the creation of The Flash, The Joker, Plastic Man, Sandman, Mr. Freeze, Killer Frost, Swamp Thing, Poison Ivy, the Parasite, the Floronic Man, Static, Beast Boy, Beast, Cyborg, Doctor Octopus and Green Goblin...and also cost Curt Connors his arm, putting him on the road to becoming The Lizard.
Doctor Doom accidentally created himself, the Fantastic Four, The Hulk, Captain Atom, and Firestorm thanks to Rasputin tricking him into making a needless correction to his portal generator's coordinates.
Dream of the Endless escaped his captivity in the mansion of Alexander Burgess thanks to the Sentinels of Magic.
