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*** [[Anime/DragonBallZFusionReborn Janemba]] and [[Anime/DragonBallZWrathOfTheDragon Hirudegarn]], despite being the embodiments of evil in each of their respective NonSerialMovie appearances, become defenseless when insulted. Especially so for Janemba, as it causes his body literally to shatter like glass. Downplayed for Hirudegarn though, as it was a weakness that was added in the dub[[note]]The original japanese dub clarified that Hirudegarn is only vulnerable to an attack when he's in the middle of doing one his own attacks[[/note]].
to:
*** [[Anime/DragonBallZFusionReborn Janemba]] and [[Anime/DragonBallZWrathOfTheDragon Hirudegarn]], despite being the embodiments of evil in each of their respective NonSerialMovie appearances, become defenseless when insulted. Especially so for Janemba, as it causes his body to literally to shatter like glass. Downplayed for Hirudegarn though, as it was a weakness that was added in the dub[[note]]The original japanese dub clarified that Hirudegarn is only vulnerable to an attack when he's in the middle of doing one his own attacks[[/note]].
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** The only way to defeat Chiaotzu's psychic attacks is to break his concentration. Krillin does this quite comically by asking him ''extremely basic math questions.'' Like 9 - 1. After that, his teacher the Crane Hermit immediately [[MundaneSolution gave him remedial math lessons]].
* ''Anime/DragonBallZ'':
** In ''Anime/DragonBallZLordSlug'', it's revealed that the sound of whistling can seriously incapacitate Namekians due to their incredibly acute senses of hearing. This becomes a plot point when Piccolo [[spoiler: asks Gohan to start whistling after [[BodyHorror ripping off his own ears]] in a desperate attempt to stop Lord Slug]].
** In ''Anime/DragonBallZTheHistoryOfTrunks'', before Trunks traveled back in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.
** In the Otherworld Tournament filler, it's revealed that Goku is exceptionally ticklish. This is exploited by Caterpy, a vastly-weaker warrior from South Quadrant, who is able to hold Goku in place and TickleTorture him for several minutes despite Goku being many times stronger than him without becoming a Super Saiyan.
** [[Anime/DragonBallZFusionReborn Janemba]] and [[Anime/DragonBallZWrathOfTheDragon Hirudegarn]], despite being the embodiments of evil in each of their respective NonSerialMovie appearances, become defenseless when enraged/insulted. Downplayed for Hirudegarn in particular as it was a weakness that was added in the dub[[note]]The original japanese dub clarified that Hirudegarn is only vulnerable to an attack when he's in the middle of doing one his own attacks[[/note]].
* ''Anime/DragonBallSuper'':
** A God of Destruction is an extremely powerful being holding its real power back. However, it turns out their existence is tied to the leading Supreme Kai of their universe. If a Supreme Kai were to be killed, the God of Destruction goes away as well. Most of the shown Supreme Kais are unfit for combat and would be easy to dispatch.
** Auta Magetta is a more direct example in that he is almost completely invulnerable and, when motivated enough, near unstoppable, even with Goku, Vegeta, and the like at the levels of power they're at. He has never been shown to have sustained physical damage of any kind. The only way he's ever been stopped is through exploitation of his low self-esteem and sensitive nature: If he hears anyone insulting him, no matter how mild, he becomes distracted and, eventually, unable to attack or even ''move'' as he's paralyzed in sadness. His friend Botamo eventually devises a MundaneSolution to this via plugging his ears while riding on Magetta's shoulders, which apparently is enough to give Super Saiyan Blue Vegeta major problems.
* ''Anime/DragonBallZ'':
** In ''Anime/DragonBallZLordSlug'', it's revealed that the sound of whistling can seriously incapacitate Namekians due to their incredibly acute senses of hearing. This becomes a plot point when Piccolo [[spoiler: asks Gohan to start whistling after [[BodyHorror ripping off his own ears]] in a desperate attempt to stop Lord Slug]].
** In ''Anime/DragonBallZTheHistoryOfTrunks'', before Trunks traveled back in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.
** In the Otherworld Tournament filler, it's revealed that Goku is exceptionally ticklish. This is exploited by Caterpy, a vastly-weaker warrior from South Quadrant, who is able to hold Goku in place and TickleTorture him for several minutes despite Goku being many times stronger than him without becoming a Super Saiyan.
** [[Anime/DragonBallZFusionReborn Janemba]] and [[Anime/DragonBallZWrathOfTheDragon Hirudegarn]], despite being the embodiments of evil in each of their respective NonSerialMovie appearances, become defenseless when enraged/insulted. Downplayed for Hirudegarn in particular as it was a weakness that was added in the dub[[note]]The original japanese dub clarified that Hirudegarn is only vulnerable to an attack when he's in the middle of doing one his own attacks[[/note]].
* ''Anime/DragonBallSuper'':
** A God of Destruction is an extremely powerful being holding its real power back. However, it turns out their existence is tied to the leading Supreme Kai of their universe. If a Supreme Kai were to be killed, the God of Destruction goes away as well. Most of the shown Supreme Kais are unfit for combat and would be easy to dispatch.
** Auta Magetta is a more direct example in that he is almost completely invulnerable and, when motivated enough, near unstoppable, even with Goku, Vegeta, and the like at the levels of power they're at. He has never been shown to have sustained physical damage of any kind. The only way he's ever been stopped is through exploitation of his low self-esteem and sensitive nature: If he hears anyone insulting him, no matter how mild, he becomes distracted and, eventually, unable to attack or even ''move'' as he's paralyzed in sadness. His friend Botamo eventually devises a MundaneSolution to this via plugging his ears while riding on Magetta's shoulders, which apparently is enough to give Super Saiyan Blue Vegeta major problems.
to:
** The Original Series:
*** The only way to defeat Chiaotzu's psychic attacks is to break his concentration. Krillin does this quite comically by asking him ''extremely basic math questions.'' Like 9 - 1. After that, his teacher the Crane Hermit immediately [[MundaneSolution gave him remedial math lessons]].
* ** ''Anime/DragonBallZ'':
** *** In ''Anime/DragonBallZLordSlug'', it's revealed that the sound of whistling can seriously incapacitate Namekians due to their incredibly acute senses of hearing. This becomes a plot point when Piccolo [[spoiler: asks Gohan to start whistling after [[BodyHorror ripping off his own ears]] in a desperate attempt to stop Lord Slug]].
** *** In ''Anime/DragonBallZTheHistoryOfTrunks'', before Trunks traveled back in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.
** *** In the Otherworld Tournament filler, it's revealed that Goku is exceptionally ticklish. This is exploited by Caterpy, a vastly-weaker warrior from South Quadrant, who is able to hold Goku in place and TickleTorture him for several minutes despite Goku being many times stronger than him without becoming a Super Saiyan.
** *** [[Anime/DragonBallZFusionReborn Janemba]] and [[Anime/DragonBallZWrathOfTheDragon Hirudegarn]], despite being the embodiments of evil in each of their respective NonSerialMovie appearances, become defenseless when enraged/insulted. insulted. Especially so for Janemba, as it causes his body literally to shatter like glass. Downplayed for Hirudegarn in particular though, as it was a weakness that was added in the dub[[note]]The original japanese dub clarified that Hirudegarn is only vulnerable to an attack when he's in the middle of doing one his own attacks[[/note]].
* ** ''Anime/DragonBallSuper'':
** *** A God of Destruction is an extremely powerful being holding its real power back. However, it turns out their existence is tied to the leading Supreme Kai of their universe. If a Supreme Kai were to be killed, the God of Destruction goes away as well. Most of the shown Supreme Kais are unfit for combat and would be easy to dispatch.
** *** Auta Magetta is a more direct example in that he is almost completely invulnerable and, when motivated enough, near unstoppable, even with Goku, Vegeta, and the like at the levels of power they're at. He has never been shown to have sustained physical damage of any kind. The only way he's ever been stopped is through exploitation of his low self-esteem and sensitive nature: If he hears anyone insulting him, no matter how mild, he becomes distracted and, eventually, unable to attack or even ''move'' as he's paralyzed in sadness. His friend Botamo eventually devises a MundaneSolution to this via plugging his ears while riding on Magetta's shoulders, which apparently is enough to give Super Saiyan Blue Vegeta major problems.problems.
** ''Anime/DragonBallGT'':
*** Goku's ticklishness would ultimately lead to his loss in the Junior's Division of the 31st World Martial Arts Tournament, albeit after an (unintentional) distraction by Vegeta.
*** The only way to defeat Chiaotzu's psychic attacks is to break his concentration. Krillin does this quite comically by asking him ''extremely basic math questions.'' Like 9 - 1. After that, his teacher the Crane Hermit immediately [[MundaneSolution gave him remedial math lessons]].
** ''Anime/DragonBallGT'':
*** Goku's ticklishness would ultimately lead to his loss in the Junior's Division of the 31st World Martial Arts Tournament, albeit after an (unintentional) distraction by Vegeta.
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** In the Otherworld Tournament filler, Goku shows that he's exceptionally vulnerable to being tickled given that Caterpy is able to hold Goku in place and [[TickleTorture torture]] him for several minutes despite Goku being many times stronger than him without becoming a Super Saiyan.
to:
** In the Otherworld Tournament filler, it's revealed that Goku shows that he's is exceptionally vulnerable to being tickled given that Caterpy ticklish. This is exploited by Caterpy, a vastly-weaker warrior from South Quadrant, who is able to hold Goku in place and [[TickleTorture torture]] TickleTorture him for several minutes despite Goku being many times stronger than him without becoming a Super Saiyan.
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* ''Manga/TheLegendOfZeldaFourSwords2004'': Shadow Link is repulsed by light to the extent that even the glow of a fairy is enough to make him retreat.
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* ''Anime/EighthMan'': Tobor the 8th Man recharges his powers with an inhalant stored in small, thin, white tubes that he carries in a cigarette case. When the bad guys allow him OneLastSmoke before executing him, this is great; when he has a fight where kids can see him, he worries about setting a bad example by appearing to smoke.
to:
* ''Anime/EighthMan'': ''Manga/EightMan1963'': Tobor the 8th Man recharges his powers with an inhalant stored in small, thin, white tubes that he carries in a cigarette case. When the bad guys allow him OneLastSmoke before executing him, this is great; when he has a fight where kids can see him, he worries about setting a bad example by appearing to smoke.
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** The sound of whistling can seriously incapacitate Namekians, as a result of their incredibly acute senses of hearing. This becomes a plot point in ''Anime/DragonBallZLordSlug'' where Piccolo [[spoiler: asks Gohan to start whistling after [[BodyHorror ripping off his own ears]] in a desperate attempt to stop Lord Slug]].
to:
* ''Anime/DragonBallZ'':
**The In ''Anime/DragonBallZLordSlug'', it's revealed that the sound of whistling can seriously incapacitate Namekians, as a result of Namekians due to their incredibly acute senses of hearing. This becomes a plot point in ''Anime/DragonBallZLordSlug'' where when Piccolo [[spoiler: asks Gohan to start whistling after [[BodyHorror ripping off his own ears]] in a desperate attempt to stop Lord Slug]].Slug]].
** In ''Anime/DragonBallZTheHistoryOfTrunks'', before Trunks traveled back in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.
**
** In ''Anime/DragonBallZTheHistoryOfTrunks'', before Trunks traveled back in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.
Changed line(s) 16,17 (click to see context) from:
** In each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted. Downplayed for the former- this was a weakness added in the dub, as the original version clarified that you could only attack Hirudegarn when he became vulnerable and attacked you.
* In ''Anime/DragonBallZ'', before Trunks traveled back in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.
* In ''Anime/DragonBallZ'', before Trunks traveled back in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.
to:
** In [[Anime/DragonBallZFusionReborn Janemba]] and [[Anime/DragonBallZWrathOfTheDragon Hirudegarn]], despite being the embodiments of evil in each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted. Downplayed for the former- this Hirudegarn in particular as it was a weakness that was added in the dub, as the dub[[note]]The original version japanese dub clarified that you could only attack Hirudegarn when he became is only vulnerable and attacked you.
* In ''Anime/DragonBallZ'', before Trunks traveled backto an attack when he's in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in middle of doing one his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.own attacks[[/note]].
* In ''Anime/DragonBallZ'', before Trunks traveled back
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** In each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted. Downplayed for the former- this was a weakness added in the dub, as the original version clarified that you could only attack Hirudegarn when he became vulnerable.
to:
** In each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted. Downplayed for the former- this was a weakness added in the dub, as the original version clarified that you could only attack Hirudegarn when he became vulnerable.vulnerable and attacked you.
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** In each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted.
to:
** In each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted. Downplayed for the former- this was a weakness added in the dub, as the original version clarified that you could only attack Hirudegarn when he became vulnerable.
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** Though this is more of a subversion in that this weakness very, very rarely becomes an issue, especially considering how many Devil Fruit users are in the series and how four of them are in the main cast. This is even lampshaded in the Enies Lobby arc; when two members of [[QuirkyMinibossSquad CP9]] are trying to decide whether or not to eat Devil Fruits that had been provided to them, [[DragonInChief Rob Lucci]] mentions that being unable to swim isn't much of a problem (then again, all members of [=CP9=] have the ability to DoubleJump, so there's that).
to:
** Though this is more of a subversion in that this weakness very, very rarely becomes an issue, especially considering how many Devil Fruit users are in the series and how four of them are in the main cast. This is even lampshaded in the Enies Lobby arc; when two members of [[QuirkyMinibossSquad CP9]] are trying to decide whether or not to eat Devil Fruits that had been provided to them, [[DragonInChief Rob Lucci]] mentions that being unable to swim isn't much of a problem (then again, all members of [=CP9=] have the ability to DoubleJump, of NotQuiteFlight, so there's that).
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* In ''Anime/DragonBallZ'', before Trunks traveled back in time to SetRightWhatOnceWentWrong, the thing that originally killed Goku wasn't some powerful world-ending foe, but a simple ''heart virus''. It's completely incurable in his time, no amount of HeroicResolve or Senzu Beans will cure it, and powering up to Super Saiyan actually speeds up its effects.
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* ''Anime/EighthMan'': Tobor the 8th Man recharges his powers with an inhalant stored in small, thin, white tubes that he carries in a cigarette case. When the bad guys allow him OneLastSmoke before executing him, this is great; when he has a fight where kids can see him, he worries about setting a bad example by appearing to smoke.
* ''Manga/AhMyGoddess'':
** Urd is put to sleep by Enka music, traditional Japanese ballads (in the Viz translation, it becomes polka music). When someone tries to take advantage of this fact, [[MundaneSolution she just pops in earplugs]].
** Mara is weak to rock music; it causes her to dance uncontrollably.
* Shiina from ''Anime/AngelBeats'' is Manga/{{Ranma|OneHalf}} turned [[ExaggeratedTrope Up to Eleven]]: a ridiculously hypercompetent ninja, but when she sees a puppy about to go over a waterfall she instinctively does a StupidSacrifice, getting them both killed...and it was a ''stuffed'' puppy. The puppy trap was actually meant for Angel, so it's possible she has the same weakness.
* In ''Manga/{{Bleach}}'', the Noveno Espada Aaroniero Arruruerie can't use his shapeshifting when in sunlight. Though he can still use any of his other 30,000+ powers (not that he does before getting killed, but he had the option). To make matters worse, he lives in Hueco Mundo, which has no natural sun. His boss builds a fake one for no discernible reason.
* In the ''Anime/CowboyBebop'' episode "[[Recap/CowboyBebopSession20PierrotLeFou Pierrot le Fou]]", Tongpu is a psychotic, unstoppable, bulletproof PsychopathicManchild. He has exactly two weaknesses, both psychological: [[WhyDidItHaveToBeSnakes a pathological fear of cats]] due to the experiments that he was subjected to, and [[spoiler:[[MinorInjuryOverreaction feeling pain]], induced in this case by Spike hurling a knife (a projectile too slow to be stopped by Pierrot's experimental shield) into his thigh]].
* From ''Manga/CromartieHighSchool'':
--> My name is Yutaka Takenouchi, and I have only one weakness ... I am ''very'' susceptible to motion sickness!
* ''Manga/{{Dandadan}}'': The mantis shrimp Gig Worker has the punching ability of a mantis shrimp, and is ''even more powerful'' underwater, but ''doesn't have gills'', so it keeps having to surface to breathe.
* ''Manga/DontMeddleWithMyDaughter'': As a goddess, Athena possesses Herculean [[FlyingBrick strength and nigh-invulnerability]]. So her enemies learned to use her feminine modesty [[DefeatByModesty against her]], by sexually molesting her in public.
* ''Manga/DragonBall'':
** The only way to defeat Chiaotzu's psychic attacks is to break his concentration. Krillin does this quite comically by asking him ''extremely basic math questions.'' Like 9 - 1. After that, his teacher the Crane Hermit immediately [[MundaneSolution gave him remedial math lessons]].
** The sound of whistling can seriously incapacitate Namekians, as a result of their incredibly acute senses of hearing. This becomes a plot point in ''Anime/DragonBallZLordSlug'' where Piccolo [[spoiler: asks Gohan to start whistling after [[BodyHorror ripping off his own ears]] in a desperate attempt to stop Lord Slug]].
** In the Otherworld Tournament filler, Goku shows that he's exceptionally vulnerable to being tickled given that Caterpy is able to hold Goku in place and [[TickleTorture torture]] him for several minutes despite Goku being many times stronger than him without becoming a Super Saiyan.
** In each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted.
* ''Anime/DragonBallSuper'':
** A God of Destruction is an extremely powerful being holding its real power back. However, it turns out their existence is tied to the leading Supreme Kai of their universe. If a Supreme Kai were to be killed, the God of Destruction goes away as well. Most of the shown Supreme Kais are unfit for combat and would be easy to dispatch.
** Auta Magetta is a more direct example in that he is almost completely invulnerable and, when motivated enough, near unstoppable, even with Goku, Vegeta, and the like at the levels of power they're at. He has never been shown to have sustained physical damage of any kind. The only way he's ever been stopped is through exploitation of his low self-esteem and sensitive nature: If he hears anyone insulting him, no matter how mild, he becomes distracted and, eventually, unable to attack or even ''move'' as he's paralyzed in sadness. His friend Botamo eventually devises a MundaneSolution to this via plugging his ears while riding on Magetta's shoulders, which apparently is enough to give Super Saiyan Blue Vegeta major problems.
* ''Literature/{{Durarara}}'':
** Celty is an immortal dullahan, but has a couple of absurd weaknesses:
*** She is ''terrified'' of aliens. In a special side story, she tries to play a video game with 'Blue Kappas' as the monsters with the logic that since they're not aliens, she'll be fine. Unfortunately, the monsters are indeed aliens and she's found an hour later, hiding in a closet.
*** [[spoiler:If someone can get her angry enough, such as in the case of Kasane possessing Shinra, Celty will almost instantly turn into an amorphous, insentient monster.]]
** Saika can also be undermined if someone has a strong enough pain tolerance, and thus she will be unable to possess them.
** Despite guns, knives and trucks being ineffective against Shizuo, as it turns out, pens work. Somehow. He also is just as vulnerable to suffocation as anyone else.
** Downplayed in Ruri's case since, as a dhampir, she only gets sunburns very easily and does not like garlic.
* ''Manga/FairyTail'':
** Natsu is MadeOfIron, he can breathe fire and cause [[PersonOfMassDestruction massive property damage simply by punching someone]], but he too suffers from the ignominious susceptibility to ''transportation''. At least once it was actually exploited to defeat him in battle. This motion sickness seems to extend to being carried by people, as well. He's perfectly fine being taken to flight by Happy the cat, however, reasoning that Happy isn't a vehicle. According to Rogue, ''all'' Dragon Slayers suffer from this.
** Wendy however, doesn't suffer from transportation. Rather, She's weak to pickled plums. [[spoiler: After the 1-year timeskip, she started to suffer from transportation.]]
** Gajeel, similarly only began suffering from motion sickness after joining Fairy Tail. It's never explained why it never bothered him before, only that eventually all Dragon Slayers gain this weakness. Even the artificially-created ones like Laxus and Cobra suffer from it.
** [[spoiler:The first Dragon Slayer Irene Belserion]] eventually explains that this is because becoming a Dragon Slayer involves being infused with Dragon magic, which effectively makes them part Dragon. As a Dragon Slayer's power increases, they become more Dragon-like [[spoiler:to the point of ''becoming'' Dragons if the process isn't halted somehow]]. The BizarreAlienSenses of Dragons don't mix well with human bodies, [[spoiler:and even Acnologia, the [[NighInvulnerability nigh-invulnerable]] [[TheJuggernaut unstoppable]] Dragon King is just as vulnerable, nearly throwing up from literally ''holding onto the side of a speeding airship'']].
* In ''Manga/FukashigiPhilia'', the villain Shidow is extremely fearful towards water to the point if he gets in contact with it, he will go berserk and have his abilities neutralized.
** All of the Abilities Users created by [[spoiler:Noa and Isumi]] have a particular weakness - it's usually whatever originally killed them (such as water for Shidow, who drowned, or dry ice for another, who froze to death).
* ''Manga/FullmetalAlchemist'':
** In the manga and second anime, Pride can project razor-sharp tentacle-like [[LivingShadow shadows]] from his body. But he can only project them where ordinary shadows could be cast; complete darkness renders him unable to attack and bright lights can cut off his tentacles. Granted, he is still near immortal even when he can't attack; in a way he is both the most powerful and the most vulnerable homunculus.
** A common mistake for people in the series is to assume that Flame Alchemist Roy Mustang is useless when wet (or without his gloves). This is only true to a certain extent - while his gloves can't create a spark when they're wet, there's nothing stopping him from using something else in their place (like a lighter) as long as he has access to the right kind of transmutation circle. He's arguably ''more'' dangerous with lots of water around so long as he has an alternative method of creating a spark, as he can split the water into hydrogen and oxygen and then ignite it... the problem is that unless he can trap the target in an enclosed area with the water he's liable to blow up any nearby allies and ''himself'' at the same time, hence this technique being very rarely used. The joking doesn't change the fact that he definitely [[ColonelBadass earned his rank]].
** A combination of this and BerserkButton: Insulting [[PintSizedPowerhouse Ed's]] height, while entertaining, has a tendency to impair his judgement as he blindly charges the enemy. This is mostly PlayedForLaughs, although [[CreepyChild Pride]] uses it once to get an edge in combat.
---> '''Pride''': Appearances can often be deceiving. Isn't that right, little alchemist?\\
'''Ed''': Grk!\\
''(Pride attacks)''
** PlayedForLaughs in one of the manga's early omake, where Hawkeye defeats both Ed and Al with ''[[ItMakesSenseInContext a magnet]]''.
* Shiina in ''Manga/GourmetGirlGraffiti'' '''absolutely''' can't be splashed by rain; any amount would make her [[InstantIllness instantly sick]] for a whole week. This is why she was wearing a whole hazmat gear when she's "risking it" to the cram school in chapter 6/episode 4. Dishwater apparently does the same thing, as seen in episode 7.
* Italy from ''Webcomic/HetaliaAxisPowers'' can run insanely fast, and [[spoiler: defeated the Ottoman Empire, which was pretty powerful at the time, while he was only a child]]. According to the author, the only thing keeping him from dominating Europe is that he's just too afraid to.
* [[OurFairiesAreDifferent Fairies]] from ''Literature/HumanityHasDeclined'' are killed by EM waves, a.k.a. light, the most ubiquitous thing in the universe. If the setting wasn't AfterTheEnd, they'd be screwed, and they still have problems with it anyway.
* ''Manga/JoJosBizarreAdventure'':
** Vampires are seen as nearly invincible gods among men...unless the sun is out. Or you punch them with sunlight-infused martial arts. Or you hit them ''really'' hard in the brain and screw up their ability to control their own bodily functions (though not many beings out there ''aren't'' weak to the ChunkySalsaRule). Or just have a Pillar Man (essentially super vampires) so much as touch them, which will cause them to be instantly absorbed.
** Pillar Men also have a weakness to the sun and Hamon, but due to their biology (and possibly Kars' stone masks) they [[TakenForGranite can turn themselves into something similar to stone]] blocking off UV rays. When Kars becomes the UltimateLifeform, [[OneHeroHoldTheWeaksauce he loses his weakness to the sun]] among other benefits.
** Rock Humans in part 8 are resistant to damage and fatigue, but despite being partly rock they're dependent on oxygen, "breathing" it through their skin. This means that submerging them in water causes them to rapidly "suffocate" and break apart, though Josuke probably didn't help matters when he stole the oxygen from one's body in an attempt to force him to surface.
** Some powerful Stands also incorporate this trope for narrative balance reasons. One key example is [[Manga/JoJosBizarreAdventureDiamondIsUnbreakable Part 4]]'s Red Hot Chili Pepper. Since it becomes stronger and faster the more electricity it has access to, with no stated or hinted upper limit, it can be said to be one of the most powerful stands in Part 4. But this comes with two weaksauce weaknesses; first, if you cut off its access to electricity, say, by destroying the motorcycle battery it was hiding in, it rapidly weakens and fades. Second, since salt water is such an excellent conductor, immersing it in the ocean will cause it to rapidly dissolve.
** For certain stands, ''the user'' is their weaksauce weakness. All non-automatic stands [[{{Synchronization}} share damage]] with their users, but some stands are pretty much impossible to directly hurt, like Yellow Temperance (amorphous blob), The Sun (too hot for anyone to get near it), The Fool, and Horus (can reform from sand and ice, respectively). Their ''users'', on the other hand, can be hurt like normal (and are often [[GlassCannon glass cannons]]), and their defeats will cause their stand to de-manifest.
** There's also The Hand in part 4, a Stand with the ability to ''literally erase anything, even space itself, from existence.'' A truly overpowered stand, in principle...except its user is Okuyasu: a [[JapaneseDelinquents Japanese Delinquent]] with the IQ of [[DumbMuscle a brick wall]] who doesn't have the brains to use it creatively nor the heart to actually use it directly against people.
** ''Manga/JojosBizarreAdventureStoneOcean'' has Ungalo's Stand, Bohemian Rhapsody, which has the incredible power to ''cause every single fictional character ever written to come to life''. On top of that, anyone who identifies with that character will [[YouCantFightFate be doomed to replace them and suffer the character's fate]]. This causes massive devastation across the entire world (for example, characters from ''Manga/FistOfTheNorthStar'' destroy Tokyo while reenacting their battle)... until Weather Report easily stops it dead in its tracks by creating an original character named Put-Back, who returns all of the summoned characters to their stories. As a side-effect, this also permanently renders Bohemian Rhapsody completely unusable, since any future attempts at reactivating its ability would also summon Put-Back, immediately cancelling it. Ungalo [[DespairEventHorizon instantly loses all will to live and falls into a coma]] upon realizing this.
* From ''Manga/KenichiTheMightiestDisciple'', we have Akisame Koetsuji, the Jujutsu Philosopher. Master martial artist, a doctor so skilled he can raise the recently dead, and [[TheAce master of a bazillion and six other fields]]. He's one of Kenichi's six super-powerful masters... and green peppers make him so ill that he can be held at bay simply by hanging one outside his door.
* ''Manga/{{Kinnikuman}}'' is weakened by milk. Though after he goes insane during his match against Curry Cook and ''drinks'' the stuff, it becomes apparent that he just thinks it's disgusting.
* Emperor Nightmare, the leader of Nightmare Enterprises (Holy Nightmare Co. in the Japanese version) in ''Anime/KirbyRightBackAtYa'', is weak against AND afraid of [[spoiler:one weapon that Kirby can take control of by swallowing his Warp Star: the Star Rod]].
-->'''Nightmare''': Aaaah! How did Kirby discover the secret?! That pitiful little Star Warrior has found my only weakness! [[spoiler:I am helpless against the power of the Star Rod! [[DeathCryEcho WAAAAUUUUGGGGHHH!!!!]]]]
* ''Anime/{{Macross}}'':
** ''Anime/SuperDimensionFortressMacross'' has an alien attack force made up of gigantic ScaryDogmaticAliens who are a {{Proud Warrior Race|Guy}} do a mass MookFaceTurn because of... singing. And souvenirs. In fairness, it does make sense in the story (at least as much as ''Literature/TheWarOfTheWorlds'' Martians being vulnerable to Earth's diseases) and is perhaps one of the best logical conclusions to a typical alien's PlanetOfHats treatment. The Zentradi have no culture to speak of other than fighting, so when exposed to humans and their culture in the form of songs and interacting with the other gender after sending a team of spies to the SDF-1, typical Zentradi start feeling emotions, questioning their purpose, and [[HumanityIsInfectious becoming similar to humans]]. Because of this, their entire fleet gets deemed "contaminated" by the unexposed Zentradi and programmed for destruction. In the face of this EnemyCivilWar, they wisely choose to ally with the humans. Still, it doesn't quite wash away the faint air of ridiculousness when Minmay's singing becomes an ''offensive weapon'' to unbalance the unexposed Zentradi in their attack.
*** Those who consider Minmei TheScrappy half-jokingly argue the Zentraedi were distracted by her singing because [[DreadfulMusician it was so bad]] in the ''Anime/{{Robotech}}'' dub.
*** The initial use of Minmay's voice as a weapon is actually short-lived: while the Zentradi were initially too distracted to react, as soon as the heroes opened fire they started firing back. The real decisive weapon in that engagement was Minmei kissing Kaifun: the Zentradi were so disgusted they stopped fighting effectively, trying absolutely anything to erase the image from their minds, including firing in the middle of nowhere (a Zentradi heavy cruiser was observed doing exactly this as Hikaru locked his nukes on it) and listening to Minmei's songs.
** Taken to even greater extremes in ''Anime/{{Macross 7}}'' where the spirit draining Protodevilns's only weakness is actually the ''energy'' produced by music. It produces a spiritual energy "too pure for them to absorb" and regenerates the lost energy in those drained by them.
*** In one humorous scene, a Protodeviln gets a "brilliant idea" for shielding himself against the humans' singing. [[MundaneSolution He puts on earplugs.]] This actually does work, but Basara just plays even louder. Afterward the Protodeviln installed a noise canceller in his mech, which proved much more effective.
*** Incidentally, one OVA shows us that Minmei's registered songs have absolutely no effect on unexposed Meltrandi (the FEMALE Zentradi), who just ignore them (partly because they had the common sense to just jam the frequencies used to broadcast them), but BASARA's songs made them groupies the very moment he managed to get them to hear him. It baffled a [[GeneralRipper UN Spacy higher-up]], who had assumed the Meltrandi would just jam the broadcast (both times the Minmei tactic had been seen used had been with broadcasts the enemy didn't jam for one reason or another).
* In ''Manga/MissKobayashisDragonMaid'' Tooru mentioned that her friend Herensuge was beaten to death by an egg without a yolk. [[ShownTheirWork This is actually a reference to the legend that Herensuge could be killed by cracking an egg on its head]].
* In ''Manga/{{Moriking}}'', the ridiculously powerful king candidates are all susceptible to cardiac arrest via consuming overly spicy food like kimchi stew or curry. Moriking and Oki find this out the hard way, but it's PlayedForLaughs and they're perfectly fine afterward.
* ''Manga/MyMonsterSecret'': Akane is an ancient demon whose powers include mind control, teleportation, shapeshifting, duplicating herself, and summoning meteors. She also has a ''massive'' SweetTooth, and anyone can foil her plans by holding up a piece of candy, which she will immediately fixate on.
* In one episode of ''Literature/MyriadColorsPhantomWorld'', the team are pitted against a [[{{Youkai}} Youkai Phantom]] in the form of a sunflower. They can't beat him until Koito works out that [[LogicalWeakness because he's a sunflower, he can only face towards the sun]]. They therefore defeat him by simply walking round him and attacking from behind, where he can't see or reach them.
* In ''Anime/TheMysteriousCitiesOfGold'', rainbow light causes the Golden Condor to malfunction and crash down on the ground.
* In ''Manga/{{Naruto}}'' Konan of the Akatsuki is, like all members of that group, very powerful. Yet her [[PaperMaster paper-based techniques]] can be completely nullified by spraying oil on her to make her stick together (a technique one human ninja and some summoned toads have), although water can release her.
** Madara once said that he's sensitive to people standing behind him, and that he couldn't so much as pee if there's someone immediately behind him. He was telling the truth.
* Adam Blade from ''Manga/{{Needless}}'' has a weakness for little girls, and usually ended up getting his butt kicked because of this. Though later in the manga his weakness had developed from mere lolis to naked lolis. On the other hand, his love for lolis can temporally boost his strength and saves him from a LotusEaterMachine, so it's subverted.
* ''Manga/OnePiece'':
** Anyone who's eaten a Devil Fruit gets amazing powers, but they all share one weakness: the inability to swim. ''At all.'' If they are so much as half-submerged in water of any kind, they become paralyzed (and for many, their powers stop working). Which is ''kind of a problem'', seeing as how many of the encountered Devil Fruit users are '''pirates or marines''' in a world that's '''''[[OceanPunk ninety percent ocean]]'''''. If a Devil Fruit user touches Seastone - a material that has been described as "solid sea" - they'll feel the same effects as if they were fully submerged in water.
** Though this is more of a subversion in that this weakness very, very rarely becomes an issue, especially considering how many Devil Fruit users are in the series and how four of them are in the main cast. This is even lampshaded in the Enies Lobby arc; when two members of [[QuirkyMinibossSquad CP9]] are trying to decide whether or not to eat Devil Fruits that had been provided to them, [[DragonInChief Rob Lucci]] mentions that being unable to swim isn't much of a problem (then again, all members of [=CP9=] have the ability to DoubleJump, so there's that).
** Depending on the situation, basic hypnosis (such as Jango's ring or Ms. Goldenweek's emotion-altering paint) serves as one of the weaknesses for Monkey D. Luffy, the protagonist. Due to his simple-minded nature, he just won't have the sense to turn away, which makes him helpless and left to the devices of his enemies.
** Water is actually a much greater weakness to [[DishingOutDirt Sir Crocodile]], as he is a man who can turn into sand, making him [[NighInvulnerability Nigh-Invulnerable]] to most attacks. But if water strikes him, the sand "sticks together," and he is rendered unable to turn into sand at all, thus leaving him fully open to attack. He has a natural defense in that his sand powers extend to causing alarmingly fast dehydration with direct skin contact. In addition, he has the good sense to not only do his villainous business on a relatively large island, but on a ''desert island.'' He also uses Dance Powder to not only to frame the king in an effort to overthrow him, but also to stop it from raining in the town he was using as a base. In addition, on the off-chance that someone was able to negate his Logia defense for a significant period of time (like with Luffy), he's a master tactician who's skilled in other combat arts as well. His hook has a second, ''poisoned'' hook under it, and if ''that'' hook gets broken, [[CrazyPrepared he can eject a knife in its place]].
** Fishmen or Fishmen-hybrids who have eaten Devil Fruits are unable to swim like any other Devil Fruit user, but unlike them, they still can breathe underwater. The problem with that is that they can't move underwater without being surrounded by a special coat of bubble.
** In-universe, at least, we have Enel. His ShockAndAwe abilities are considered among the most godlike Devil Fruit powers in the setting, yet Luffy's relatively low-tier RubberMan powers completely and utterly negated them, to the point that Enel had to get really creative with his powers just to find a way to harm Luffy at all, and only his unrelated CombatClairvoyance protected him from getting beaten to a pulp pretty much instantly.
*** Logia-type Devil Fruits in general tend to react weirdly to various elements, and almost always have at least one weakness that completely shuts down their powers. Moreover, hitting their elemental forms with [[KiManipulation Haki-infused attacks]] damages them as if they were in regular form.
** Blackbeard has one of the most powerful abilities in universe. With his Darkness manipulation, he can wipe out entire towns in seconds, shoot the debris out like a cannon, and negate other Devil Fruit powers through physical contact. But he has a major weakness that isn't shared by any other fruit of the same class as his. Most Logia-users are Nigh-Invulnerable due to being able to dematerialize around attacks, but because Blackbeard's ability makes him a "Gravity Man", his body is always in physical form. Not only that, but the same qualities that let him negate other Devil Fruit powers (by forcibly holding their bodies together) also draws attacks INTO him. In short, attacks are both more likely to hit him ''and'' always exceptionally damaging.
* ''Manga/PokemonAdventures'': Roxanne's Nosepass is very powerful, but as it is basically a living compass, it can only face north. Once an opponent can get behind it, it cannot defend itself.
* ''Manga/RanmaOneHalf'':
** Ranma Saotome can be incapacitated by [[WhyDidItHaveToBeSnakes the mere sight of a cute little kitten]]. However, those who attempt this should note to apply said weakness quickly and forcefully -- prolonged, intense exposure has a tendency to [[UnstoppableRage backfire]]. Thanks to his GenderBender curse, [[KillItWithWater cold water]] can also count as a weakness. Technically. Ranma's female form has less strength and reach than his male form (though the anime is explicit that Ranma's speed is boosted in this form, so it's more of a trade), but s/he can still pull off all of his/her normal attacks. Based on a character with an identical curse, it's also possible that being in female form weakens his [[KiManipulation Ki Attacks]].
** [[CuteBruiser Shampoo]] and Ryoga Hibiki have an even worse case of the water weakness than Ranma does; Jusenkyo made them become a [[ForcedTransformation little kitten and miniature pig]] respectively when splashed with cold water. So they go from incredibly powerful fighters to harmless little animals whose only recourse is to run or hide until they can get some hot water. Genma Saotome, Ranma's father, subverts it; his panda form loses little, if any, speed and agility while gaining in strength and toughness due to the increased [[StoutStrength bulk]]. Mousse, meanwhile, seesaws between subverting this trope and playing it straight with his duck curse; while it is much smaller, weaker and can't use his physical attacks, it can fly and he's still capable of throwing barrages of knives, darts and bombs in it.
** And a non-water version applies to [[OldMaster Happosai]], who is such a DirtyOldMan that his perversion becomes his own Achilles heel. If there is a fight serious enough, or a reward great enough, that he can't be immediately distracted from whatever he was doing by the sight of girls in skimpy clothing, bare cleavage or a bra, it hasn't come up in the series. He can even be lured right into dangers simply by tossing a bra in the right place.
** Spoiled prince Saffron has incredible fire magic powers, the ability to fly and regenerate so fast that he can tear off his own wings to use as throwing weapons and grow them back in seconds, but because of his lax and pampered upbringing he can't take any sort of physical blow and in a world full of martial artists that's a big problem.
* The specialists, the Paper Sisters in ''Anime/{{Read or D|ie}}ream'' can telekinetically manipulate paper... unless it's ''wet''. This was not a weakness for Yomiko Readman, who ''is'' shown on camera manipulating paper while underwater. This is actually [[JustifiedTrope explained in-universe]]. The Paper Sisters' powers are essentially imperfect clones of Yomiko's, artificially created by Dokusensha; which is why they are weaker and more specialized/limited. Water naturally disrupts the structural integrity of paper, and their inferior powers are not sufficient to maintain it the way Yomiko can.
** One minor villain in ''Anime/RODTheTV'' is an expert on sound, to the point of knowing a certain frequency that can [[PowerNullifier nullify]] the protagonists' PaperMaster abilities, rendering them powerless against him. Anita's solution is to just [[ThrowTheBookAtThem throw a book at him]]; A normal, unpowered hardcover book, which flies right past his defenses and hits him right in the face, knocking him out.
* In ''Manga/RosarioPlusVampire'', vampires are considered the high end of the monster scale, but the fact that you can take a vampire down with a glass of water kinda puts a [[{{Pun}} dampener]] on that idea. Though, you'd have to be of werewolf speed to even ''consider'' hitting them with the stuff in the first place. Vampires are ironically said to have the most weaknesses compared to any other monster. Things like silver would also do them in. However, they are still incredibly strong even when weakened by those weaknesses, albeit far weaker.
* The titular servamps of ''Manga/{{Servamp}}'' are made of this. They cannot swim in running water, cannot separate from their eve or both will eventually die, cannot touch holy water without collapsing, will be weakened to the point of personality changes if their contract item breaks and turn into an animal immediately when exposed to sunlight.
** Tsurugi is a magician and has the same weaknesses as a normal human would (e.i. blood loss, starvation, etc) though he is more resilient. However, as he never learned how to swim and according to himself '[he] sinks like a rock', Tsurugi is so vulnerable to drowning he can't even fill up his bathtub too much.
* In ''Literature/{{Slayers}}'', female spell-casters have a very common and mundane weakness: menstruation. During a woman's menstruation period, her magical power output drops tremendously, so much so that even the protagonist, Lina Inverse, who is one of the strongest sorceresses in the entire Slayers setting, is barely able to cast a novice ''Light'' spell during her period. This is apparently a well-known weakness, as Zelgadis and even [[IdiotHero Gourry]] both figure out why her powers are weakened at one point, though Gourry is so ignorant that he doesn't understand the significance of "that time of the month" and just assumes it's magic-related.
* The Dai Gurren in ''Anime/TengenToppaGurrenLagann'' is a walking battleship... that is not designed to go on water. A ''battleship'' that ''isn't designed to go on water''.
* ''Manga/UshioAndTora'': Youkai in general are implied to have all one or two weakness, aside from the common one to ColdIron and spiritual powers:
** The Stone Eater (a giant two-headed centipede monster) can be easily killed with a weapon moist in human spittle, a nod to the legend of Hidesato Tawaratota.
** Fusuma can only be hurt by fire and black laquered teeth. Since he also lives in the sky, Tora lampshades how difficult it is to actually take advantage of said weaknesses.
** The Vampire is afraid of fire, but also recoils from both Daoist talismans and Christian holy icons, being unable to use any of his powers in front of a crucifix.
** The jashin Hitotsuki, according to the manual, can't stand tobacco smoke.
** The Yamauo normally dwells deep below the surface, but exposure to sunlight makes him explode into smithereens.
* ''Anime/YuGiOhArcV'': Gongenzaka's Superheavy Samurai Deck functions without having Spell/Trap Cards in his Graveyards, so he cannot pick up Action Cards without handicapping him. This is normally not a problem, as his deck is pretty strong, but it makes him unsuitable in Tag Duels, where both partners share the same field and Graveyard, thus his deck is very likely to get screwed by his partner or his partner is screwed for not using Spell/Trap Cards when they actually need them. [[spoiler:Gongenzaka later gains a new ace monster that can banish Spell/Trap Cards from his Graveyard, yet it is still not suitable in Tag Duels.]]
----
* ''Manga/AhMyGoddess'':
** Urd is put to sleep by Enka music, traditional Japanese ballads (in the Viz translation, it becomes polka music). When someone tries to take advantage of this fact, [[MundaneSolution she just pops in earplugs]].
** Mara is weak to rock music; it causes her to dance uncontrollably.
* Shiina from ''Anime/AngelBeats'' is Manga/{{Ranma|OneHalf}} turned [[ExaggeratedTrope Up to Eleven]]: a ridiculously hypercompetent ninja, but when she sees a puppy about to go over a waterfall she instinctively does a StupidSacrifice, getting them both killed...and it was a ''stuffed'' puppy. The puppy trap was actually meant for Angel, so it's possible she has the same weakness.
* In ''Manga/{{Bleach}}'', the Noveno Espada Aaroniero Arruruerie can't use his shapeshifting when in sunlight. Though he can still use any of his other 30,000+ powers (not that he does before getting killed, but he had the option). To make matters worse, he lives in Hueco Mundo, which has no natural sun. His boss builds a fake one for no discernible reason.
* In the ''Anime/CowboyBebop'' episode "[[Recap/CowboyBebopSession20PierrotLeFou Pierrot le Fou]]", Tongpu is a psychotic, unstoppable, bulletproof PsychopathicManchild. He has exactly two weaknesses, both psychological: [[WhyDidItHaveToBeSnakes a pathological fear of cats]] due to the experiments that he was subjected to, and [[spoiler:[[MinorInjuryOverreaction feeling pain]], induced in this case by Spike hurling a knife (a projectile too slow to be stopped by Pierrot's experimental shield) into his thigh]].
* From ''Manga/CromartieHighSchool'':
--> My name is Yutaka Takenouchi, and I have only one weakness ... I am ''very'' susceptible to motion sickness!
* ''Manga/{{Dandadan}}'': The mantis shrimp Gig Worker has the punching ability of a mantis shrimp, and is ''even more powerful'' underwater, but ''doesn't have gills'', so it keeps having to surface to breathe.
* ''Manga/DontMeddleWithMyDaughter'': As a goddess, Athena possesses Herculean [[FlyingBrick strength and nigh-invulnerability]]. So her enemies learned to use her feminine modesty [[DefeatByModesty against her]], by sexually molesting her in public.
* ''Manga/DragonBall'':
** The only way to defeat Chiaotzu's psychic attacks is to break his concentration. Krillin does this quite comically by asking him ''extremely basic math questions.'' Like 9 - 1. After that, his teacher the Crane Hermit immediately [[MundaneSolution gave him remedial math lessons]].
** The sound of whistling can seriously incapacitate Namekians, as a result of their incredibly acute senses of hearing. This becomes a plot point in ''Anime/DragonBallZLordSlug'' where Piccolo [[spoiler: asks Gohan to start whistling after [[BodyHorror ripping off his own ears]] in a desperate attempt to stop Lord Slug]].
** In the Otherworld Tournament filler, Goku shows that he's exceptionally vulnerable to being tickled given that Caterpy is able to hold Goku in place and [[TickleTorture torture]] him for several minutes despite Goku being many times stronger than him without becoming a Super Saiyan.
** In each of their respective NonSerialMovie appearances, the embodiments of evil Hirudegarn and Janemba become defenseless when enraged/insulted.
* ''Anime/DragonBallSuper'':
** A God of Destruction is an extremely powerful being holding its real power back. However, it turns out their existence is tied to the leading Supreme Kai of their universe. If a Supreme Kai were to be killed, the God of Destruction goes away as well. Most of the shown Supreme Kais are unfit for combat and would be easy to dispatch.
** Auta Magetta is a more direct example in that he is almost completely invulnerable and, when motivated enough, near unstoppable, even with Goku, Vegeta, and the like at the levels of power they're at. He has never been shown to have sustained physical damage of any kind. The only way he's ever been stopped is through exploitation of his low self-esteem and sensitive nature: If he hears anyone insulting him, no matter how mild, he becomes distracted and, eventually, unable to attack or even ''move'' as he's paralyzed in sadness. His friend Botamo eventually devises a MundaneSolution to this via plugging his ears while riding on Magetta's shoulders, which apparently is enough to give Super Saiyan Blue Vegeta major problems.
* ''Literature/{{Durarara}}'':
** Celty is an immortal dullahan, but has a couple of absurd weaknesses:
*** She is ''terrified'' of aliens. In a special side story, she tries to play a video game with 'Blue Kappas' as the monsters with the logic that since they're not aliens, she'll be fine. Unfortunately, the monsters are indeed aliens and she's found an hour later, hiding in a closet.
*** [[spoiler:If someone can get her angry enough, such as in the case of Kasane possessing Shinra, Celty will almost instantly turn into an amorphous, insentient monster.]]
** Saika can also be undermined if someone has a strong enough pain tolerance, and thus she will be unable to possess them.
** Despite guns, knives and trucks being ineffective against Shizuo, as it turns out, pens work. Somehow. He also is just as vulnerable to suffocation as anyone else.
** Downplayed in Ruri's case since, as a dhampir, she only gets sunburns very easily and does not like garlic.
* ''Manga/FairyTail'':
** Natsu is MadeOfIron, he can breathe fire and cause [[PersonOfMassDestruction massive property damage simply by punching someone]], but he too suffers from the ignominious susceptibility to ''transportation''. At least once it was actually exploited to defeat him in battle. This motion sickness seems to extend to being carried by people, as well. He's perfectly fine being taken to flight by Happy the cat, however, reasoning that Happy isn't a vehicle. According to Rogue, ''all'' Dragon Slayers suffer from this.
** Wendy however, doesn't suffer from transportation. Rather, She's weak to pickled plums. [[spoiler: After the 1-year timeskip, she started to suffer from transportation.]]
** Gajeel, similarly only began suffering from motion sickness after joining Fairy Tail. It's never explained why it never bothered him before, only that eventually all Dragon Slayers gain this weakness. Even the artificially-created ones like Laxus and Cobra suffer from it.
** [[spoiler:The first Dragon Slayer Irene Belserion]] eventually explains that this is because becoming a Dragon Slayer involves being infused with Dragon magic, which effectively makes them part Dragon. As a Dragon Slayer's power increases, they become more Dragon-like [[spoiler:to the point of ''becoming'' Dragons if the process isn't halted somehow]]. The BizarreAlienSenses of Dragons don't mix well with human bodies, [[spoiler:and even Acnologia, the [[NighInvulnerability nigh-invulnerable]] [[TheJuggernaut unstoppable]] Dragon King is just as vulnerable, nearly throwing up from literally ''holding onto the side of a speeding airship'']].
* In ''Manga/FukashigiPhilia'', the villain Shidow is extremely fearful towards water to the point if he gets in contact with it, he will go berserk and have his abilities neutralized.
** All of the Abilities Users created by [[spoiler:Noa and Isumi]] have a particular weakness - it's usually whatever originally killed them (such as water for Shidow, who drowned, or dry ice for another, who froze to death).
* ''Manga/FullmetalAlchemist'':
** In the manga and second anime, Pride can project razor-sharp tentacle-like [[LivingShadow shadows]] from his body. But he can only project them where ordinary shadows could be cast; complete darkness renders him unable to attack and bright lights can cut off his tentacles. Granted, he is still near immortal even when he can't attack; in a way he is both the most powerful and the most vulnerable homunculus.
** A common mistake for people in the series is to assume that Flame Alchemist Roy Mustang is useless when wet (or without his gloves). This is only true to a certain extent - while his gloves can't create a spark when they're wet, there's nothing stopping him from using something else in their place (like a lighter) as long as he has access to the right kind of transmutation circle. He's arguably ''more'' dangerous with lots of water around so long as he has an alternative method of creating a spark, as he can split the water into hydrogen and oxygen and then ignite it... the problem is that unless he can trap the target in an enclosed area with the water he's liable to blow up any nearby allies and ''himself'' at the same time, hence this technique being very rarely used. The joking doesn't change the fact that he definitely [[ColonelBadass earned his rank]].
** A combination of this and BerserkButton: Insulting [[PintSizedPowerhouse Ed's]] height, while entertaining, has a tendency to impair his judgement as he blindly charges the enemy. This is mostly PlayedForLaughs, although [[CreepyChild Pride]] uses it once to get an edge in combat.
---> '''Pride''': Appearances can often be deceiving. Isn't that right, little alchemist?\\
'''Ed''': Grk!\\
''(Pride attacks)''
** PlayedForLaughs in one of the manga's early omake, where Hawkeye defeats both Ed and Al with ''[[ItMakesSenseInContext a magnet]]''.
* Shiina in ''Manga/GourmetGirlGraffiti'' '''absolutely''' can't be splashed by rain; any amount would make her [[InstantIllness instantly sick]] for a whole week. This is why she was wearing a whole hazmat gear when she's "risking it" to the cram school in chapter 6/episode 4. Dishwater apparently does the same thing, as seen in episode 7.
* Italy from ''Webcomic/HetaliaAxisPowers'' can run insanely fast, and [[spoiler: defeated the Ottoman Empire, which was pretty powerful at the time, while he was only a child]]. According to the author, the only thing keeping him from dominating Europe is that he's just too afraid to.
* [[OurFairiesAreDifferent Fairies]] from ''Literature/HumanityHasDeclined'' are killed by EM waves, a.k.a. light, the most ubiquitous thing in the universe. If the setting wasn't AfterTheEnd, they'd be screwed, and they still have problems with it anyway.
* ''Manga/JoJosBizarreAdventure'':
** Vampires are seen as nearly invincible gods among men...unless the sun is out. Or you punch them with sunlight-infused martial arts. Or you hit them ''really'' hard in the brain and screw up their ability to control their own bodily functions (though not many beings out there ''aren't'' weak to the ChunkySalsaRule). Or just have a Pillar Man (essentially super vampires) so much as touch them, which will cause them to be instantly absorbed.
** Pillar Men also have a weakness to the sun and Hamon, but due to their biology (and possibly Kars' stone masks) they [[TakenForGranite can turn themselves into something similar to stone]] blocking off UV rays. When Kars becomes the UltimateLifeform, [[OneHeroHoldTheWeaksauce he loses his weakness to the sun]] among other benefits.
** Rock Humans in part 8 are resistant to damage and fatigue, but despite being partly rock they're dependent on oxygen, "breathing" it through their skin. This means that submerging them in water causes them to rapidly "suffocate" and break apart, though Josuke probably didn't help matters when he stole the oxygen from one's body in an attempt to force him to surface.
** Some powerful Stands also incorporate this trope for narrative balance reasons. One key example is [[Manga/JoJosBizarreAdventureDiamondIsUnbreakable Part 4]]'s Red Hot Chili Pepper. Since it becomes stronger and faster the more electricity it has access to, with no stated or hinted upper limit, it can be said to be one of the most powerful stands in Part 4. But this comes with two weaksauce weaknesses; first, if you cut off its access to electricity, say, by destroying the motorcycle battery it was hiding in, it rapidly weakens and fades. Second, since salt water is such an excellent conductor, immersing it in the ocean will cause it to rapidly dissolve.
** For certain stands, ''the user'' is their weaksauce weakness. All non-automatic stands [[{{Synchronization}} share damage]] with their users, but some stands are pretty much impossible to directly hurt, like Yellow Temperance (amorphous blob), The Sun (too hot for anyone to get near it), The Fool, and Horus (can reform from sand and ice, respectively). Their ''users'', on the other hand, can be hurt like normal (and are often [[GlassCannon glass cannons]]), and their defeats will cause their stand to de-manifest.
** There's also The Hand in part 4, a Stand with the ability to ''literally erase anything, even space itself, from existence.'' A truly overpowered stand, in principle...except its user is Okuyasu: a [[JapaneseDelinquents Japanese Delinquent]] with the IQ of [[DumbMuscle a brick wall]] who doesn't have the brains to use it creatively nor the heart to actually use it directly against people.
** ''Manga/JojosBizarreAdventureStoneOcean'' has Ungalo's Stand, Bohemian Rhapsody, which has the incredible power to ''cause every single fictional character ever written to come to life''. On top of that, anyone who identifies with that character will [[YouCantFightFate be doomed to replace them and suffer the character's fate]]. This causes massive devastation across the entire world (for example, characters from ''Manga/FistOfTheNorthStar'' destroy Tokyo while reenacting their battle)... until Weather Report easily stops it dead in its tracks by creating an original character named Put-Back, who returns all of the summoned characters to their stories. As a side-effect, this also permanently renders Bohemian Rhapsody completely unusable, since any future attempts at reactivating its ability would also summon Put-Back, immediately cancelling it. Ungalo [[DespairEventHorizon instantly loses all will to live and falls into a coma]] upon realizing this.
* From ''Manga/KenichiTheMightiestDisciple'', we have Akisame Koetsuji, the Jujutsu Philosopher. Master martial artist, a doctor so skilled he can raise the recently dead, and [[TheAce master of a bazillion and six other fields]]. He's one of Kenichi's six super-powerful masters... and green peppers make him so ill that he can be held at bay simply by hanging one outside his door.
* ''Manga/{{Kinnikuman}}'' is weakened by milk. Though after he goes insane during his match against Curry Cook and ''drinks'' the stuff, it becomes apparent that he just thinks it's disgusting.
* Emperor Nightmare, the leader of Nightmare Enterprises (Holy Nightmare Co. in the Japanese version) in ''Anime/KirbyRightBackAtYa'', is weak against AND afraid of [[spoiler:one weapon that Kirby can take control of by swallowing his Warp Star: the Star Rod]].
-->'''Nightmare''': Aaaah! How did Kirby discover the secret?! That pitiful little Star Warrior has found my only weakness! [[spoiler:I am helpless against the power of the Star Rod! [[DeathCryEcho WAAAAUUUUGGGGHHH!!!!]]]]
* ''Anime/{{Macross}}'':
** ''Anime/SuperDimensionFortressMacross'' has an alien attack force made up of gigantic ScaryDogmaticAliens who are a {{Proud Warrior Race|Guy}} do a mass MookFaceTurn because of... singing. And souvenirs. In fairness, it does make sense in the story (at least as much as ''Literature/TheWarOfTheWorlds'' Martians being vulnerable to Earth's diseases) and is perhaps one of the best logical conclusions to a typical alien's PlanetOfHats treatment. The Zentradi have no culture to speak of other than fighting, so when exposed to humans and their culture in the form of songs and interacting with the other gender after sending a team of spies to the SDF-1, typical Zentradi start feeling emotions, questioning their purpose, and [[HumanityIsInfectious becoming similar to humans]]. Because of this, their entire fleet gets deemed "contaminated" by the unexposed Zentradi and programmed for destruction. In the face of this EnemyCivilWar, they wisely choose to ally with the humans. Still, it doesn't quite wash away the faint air of ridiculousness when Minmay's singing becomes an ''offensive weapon'' to unbalance the unexposed Zentradi in their attack.
*** Those who consider Minmei TheScrappy half-jokingly argue the Zentraedi were distracted by her singing because [[DreadfulMusician it was so bad]] in the ''Anime/{{Robotech}}'' dub.
*** The initial use of Minmay's voice as a weapon is actually short-lived: while the Zentradi were initially too distracted to react, as soon as the heroes opened fire they started firing back. The real decisive weapon in that engagement was Minmei kissing Kaifun: the Zentradi were so disgusted they stopped fighting effectively, trying absolutely anything to erase the image from their minds, including firing in the middle of nowhere (a Zentradi heavy cruiser was observed doing exactly this as Hikaru locked his nukes on it) and listening to Minmei's songs.
** Taken to even greater extremes in ''Anime/{{Macross 7}}'' where the spirit draining Protodevilns's only weakness is actually the ''energy'' produced by music. It produces a spiritual energy "too pure for them to absorb" and regenerates the lost energy in those drained by them.
*** In one humorous scene, a Protodeviln gets a "brilliant idea" for shielding himself against the humans' singing. [[MundaneSolution He puts on earplugs.]] This actually does work, but Basara just plays even louder. Afterward the Protodeviln installed a noise canceller in his mech, which proved much more effective.
*** Incidentally, one OVA shows us that Minmei's registered songs have absolutely no effect on unexposed Meltrandi (the FEMALE Zentradi), who just ignore them (partly because they had the common sense to just jam the frequencies used to broadcast them), but BASARA's songs made them groupies the very moment he managed to get them to hear him. It baffled a [[GeneralRipper UN Spacy higher-up]], who had assumed the Meltrandi would just jam the broadcast (both times the Minmei tactic had been seen used had been with broadcasts the enemy didn't jam for one reason or another).
* In ''Manga/MissKobayashisDragonMaid'' Tooru mentioned that her friend Herensuge was beaten to death by an egg without a yolk. [[ShownTheirWork This is actually a reference to the legend that Herensuge could be killed by cracking an egg on its head]].
* In ''Manga/{{Moriking}}'', the ridiculously powerful king candidates are all susceptible to cardiac arrest via consuming overly spicy food like kimchi stew or curry. Moriking and Oki find this out the hard way, but it's PlayedForLaughs and they're perfectly fine afterward.
* ''Manga/MyMonsterSecret'': Akane is an ancient demon whose powers include mind control, teleportation, shapeshifting, duplicating herself, and summoning meteors. She also has a ''massive'' SweetTooth, and anyone can foil her plans by holding up a piece of candy, which she will immediately fixate on.
* In one episode of ''Literature/MyriadColorsPhantomWorld'', the team are pitted against a [[{{Youkai}} Youkai Phantom]] in the form of a sunflower. They can't beat him until Koito works out that [[LogicalWeakness because he's a sunflower, he can only face towards the sun]]. They therefore defeat him by simply walking round him and attacking from behind, where he can't see or reach them.
* In ''Anime/TheMysteriousCitiesOfGold'', rainbow light causes the Golden Condor to malfunction and crash down on the ground.
* In ''Manga/{{Naruto}}'' Konan of the Akatsuki is, like all members of that group, very powerful. Yet her [[PaperMaster paper-based techniques]] can be completely nullified by spraying oil on her to make her stick together (a technique one human ninja and some summoned toads have), although water can release her.
** Madara once said that he's sensitive to people standing behind him, and that he couldn't so much as pee if there's someone immediately behind him. He was telling the truth.
* Adam Blade from ''Manga/{{Needless}}'' has a weakness for little girls, and usually ended up getting his butt kicked because of this. Though later in the manga his weakness had developed from mere lolis to naked lolis. On the other hand, his love for lolis can temporally boost his strength and saves him from a LotusEaterMachine, so it's subverted.
* ''Manga/OnePiece'':
** Anyone who's eaten a Devil Fruit gets amazing powers, but they all share one weakness: the inability to swim. ''At all.'' If they are so much as half-submerged in water of any kind, they become paralyzed (and for many, their powers stop working). Which is ''kind of a problem'', seeing as how many of the encountered Devil Fruit users are '''pirates or marines''' in a world that's '''''[[OceanPunk ninety percent ocean]]'''''. If a Devil Fruit user touches Seastone - a material that has been described as "solid sea" - they'll feel the same effects as if they were fully submerged in water.
** Though this is more of a subversion in that this weakness very, very rarely becomes an issue, especially considering how many Devil Fruit users are in the series and how four of them are in the main cast. This is even lampshaded in the Enies Lobby arc; when two members of [[QuirkyMinibossSquad CP9]] are trying to decide whether or not to eat Devil Fruits that had been provided to them, [[DragonInChief Rob Lucci]] mentions that being unable to swim isn't much of a problem (then again, all members of [=CP9=] have the ability to DoubleJump, so there's that).
** Depending on the situation, basic hypnosis (such as Jango's ring or Ms. Goldenweek's emotion-altering paint) serves as one of the weaknesses for Monkey D. Luffy, the protagonist. Due to his simple-minded nature, he just won't have the sense to turn away, which makes him helpless and left to the devices of his enemies.
** Water is actually a much greater weakness to [[DishingOutDirt Sir Crocodile]], as he is a man who can turn into sand, making him [[NighInvulnerability Nigh-Invulnerable]] to most attacks. But if water strikes him, the sand "sticks together," and he is rendered unable to turn into sand at all, thus leaving him fully open to attack. He has a natural defense in that his sand powers extend to causing alarmingly fast dehydration with direct skin contact. In addition, he has the good sense to not only do his villainous business on a relatively large island, but on a ''desert island.'' He also uses Dance Powder to not only to frame the king in an effort to overthrow him, but also to stop it from raining in the town he was using as a base. In addition, on the off-chance that someone was able to negate his Logia defense for a significant period of time (like with Luffy), he's a master tactician who's skilled in other combat arts as well. His hook has a second, ''poisoned'' hook under it, and if ''that'' hook gets broken, [[CrazyPrepared he can eject a knife in its place]].
** Fishmen or Fishmen-hybrids who have eaten Devil Fruits are unable to swim like any other Devil Fruit user, but unlike them, they still can breathe underwater. The problem with that is that they can't move underwater without being surrounded by a special coat of bubble.
** In-universe, at least, we have Enel. His ShockAndAwe abilities are considered among the most godlike Devil Fruit powers in the setting, yet Luffy's relatively low-tier RubberMan powers completely and utterly negated them, to the point that Enel had to get really creative with his powers just to find a way to harm Luffy at all, and only his unrelated CombatClairvoyance protected him from getting beaten to a pulp pretty much instantly.
*** Logia-type Devil Fruits in general tend to react weirdly to various elements, and almost always have at least one weakness that completely shuts down their powers. Moreover, hitting their elemental forms with [[KiManipulation Haki-infused attacks]] damages them as if they were in regular form.
** Blackbeard has one of the most powerful abilities in universe. With his Darkness manipulation, he can wipe out entire towns in seconds, shoot the debris out like a cannon, and negate other Devil Fruit powers through physical contact. But he has a major weakness that isn't shared by any other fruit of the same class as his. Most Logia-users are Nigh-Invulnerable due to being able to dematerialize around attacks, but because Blackbeard's ability makes him a "Gravity Man", his body is always in physical form. Not only that, but the same qualities that let him negate other Devil Fruit powers (by forcibly holding their bodies together) also draws attacks INTO him. In short, attacks are both more likely to hit him ''and'' always exceptionally damaging.
* ''Manga/PokemonAdventures'': Roxanne's Nosepass is very powerful, but as it is basically a living compass, it can only face north. Once an opponent can get behind it, it cannot defend itself.
* ''Manga/RanmaOneHalf'':
** Ranma Saotome can be incapacitated by [[WhyDidItHaveToBeSnakes the mere sight of a cute little kitten]]. However, those who attempt this should note to apply said weakness quickly and forcefully -- prolonged, intense exposure has a tendency to [[UnstoppableRage backfire]]. Thanks to his GenderBender curse, [[KillItWithWater cold water]] can also count as a weakness. Technically. Ranma's female form has less strength and reach than his male form (though the anime is explicit that Ranma's speed is boosted in this form, so it's more of a trade), but s/he can still pull off all of his/her normal attacks. Based on a character with an identical curse, it's also possible that being in female form weakens his [[KiManipulation Ki Attacks]].
** [[CuteBruiser Shampoo]] and Ryoga Hibiki have an even worse case of the water weakness than Ranma does; Jusenkyo made them become a [[ForcedTransformation little kitten and miniature pig]] respectively when splashed with cold water. So they go from incredibly powerful fighters to harmless little animals whose only recourse is to run or hide until they can get some hot water. Genma Saotome, Ranma's father, subverts it; his panda form loses little, if any, speed and agility while gaining in strength and toughness due to the increased [[StoutStrength bulk]]. Mousse, meanwhile, seesaws between subverting this trope and playing it straight with his duck curse; while it is much smaller, weaker and can't use his physical attacks, it can fly and he's still capable of throwing barrages of knives, darts and bombs in it.
** And a non-water version applies to [[OldMaster Happosai]], who is such a DirtyOldMan that his perversion becomes his own Achilles heel. If there is a fight serious enough, or a reward great enough, that he can't be immediately distracted from whatever he was doing by the sight of girls in skimpy clothing, bare cleavage or a bra, it hasn't come up in the series. He can even be lured right into dangers simply by tossing a bra in the right place.
** Spoiled prince Saffron has incredible fire magic powers, the ability to fly and regenerate so fast that he can tear off his own wings to use as throwing weapons and grow them back in seconds, but because of his lax and pampered upbringing he can't take any sort of physical blow and in a world full of martial artists that's a big problem.
* The specialists, the Paper Sisters in ''Anime/{{Read or D|ie}}ream'' can telekinetically manipulate paper... unless it's ''wet''. This was not a weakness for Yomiko Readman, who ''is'' shown on camera manipulating paper while underwater. This is actually [[JustifiedTrope explained in-universe]]. The Paper Sisters' powers are essentially imperfect clones of Yomiko's, artificially created by Dokusensha; which is why they are weaker and more specialized/limited. Water naturally disrupts the structural integrity of paper, and their inferior powers are not sufficient to maintain it the way Yomiko can.
** One minor villain in ''Anime/RODTheTV'' is an expert on sound, to the point of knowing a certain frequency that can [[PowerNullifier nullify]] the protagonists' PaperMaster abilities, rendering them powerless against him. Anita's solution is to just [[ThrowTheBookAtThem throw a book at him]]; A normal, unpowered hardcover book, which flies right past his defenses and hits him right in the face, knocking him out.
* In ''Manga/RosarioPlusVampire'', vampires are considered the high end of the monster scale, but the fact that you can take a vampire down with a glass of water kinda puts a [[{{Pun}} dampener]] on that idea. Though, you'd have to be of werewolf speed to even ''consider'' hitting them with the stuff in the first place. Vampires are ironically said to have the most weaknesses compared to any other monster. Things like silver would also do them in. However, they are still incredibly strong even when weakened by those weaknesses, albeit far weaker.
* The titular servamps of ''Manga/{{Servamp}}'' are made of this. They cannot swim in running water, cannot separate from their eve or both will eventually die, cannot touch holy water without collapsing, will be weakened to the point of personality changes if their contract item breaks and turn into an animal immediately when exposed to sunlight.
** Tsurugi is a magician and has the same weaknesses as a normal human would (e.i. blood loss, starvation, etc) though he is more resilient. However, as he never learned how to swim and according to himself '[he] sinks like a rock', Tsurugi is so vulnerable to drowning he can't even fill up his bathtub too much.
* In ''Literature/{{Slayers}}'', female spell-casters have a very common and mundane weakness: menstruation. During a woman's menstruation period, her magical power output drops tremendously, so much so that even the protagonist, Lina Inverse, who is one of the strongest sorceresses in the entire Slayers setting, is barely able to cast a novice ''Light'' spell during her period. This is apparently a well-known weakness, as Zelgadis and even [[IdiotHero Gourry]] both figure out why her powers are weakened at one point, though Gourry is so ignorant that he doesn't understand the significance of "that time of the month" and just assumes it's magic-related.
* The Dai Gurren in ''Anime/TengenToppaGurrenLagann'' is a walking battleship... that is not designed to go on water. A ''battleship'' that ''isn't designed to go on water''.
* ''Manga/UshioAndTora'': Youkai in general are implied to have all one or two weakness, aside from the common one to ColdIron and spiritual powers:
** The Stone Eater (a giant two-headed centipede monster) can be easily killed with a weapon moist in human spittle, a nod to the legend of Hidesato Tawaratota.
** Fusuma can only be hurt by fire and black laquered teeth. Since he also lives in the sky, Tora lampshades how difficult it is to actually take advantage of said weaknesses.
** The Vampire is afraid of fire, but also recoils from both Daoist talismans and Christian holy icons, being unable to use any of his powers in front of a crucifix.
** The jashin Hitotsuki, according to the manual, can't stand tobacco smoke.
** The Yamauo normally dwells deep below the surface, but exposure to sunlight makes him explode into smithereens.
* ''Anime/YuGiOhArcV'': Gongenzaka's Superheavy Samurai Deck functions without having Spell/Trap Cards in his Graveyards, so he cannot pick up Action Cards without handicapping him. This is normally not a problem, as his deck is pretty strong, but it makes him unsuitable in Tag Duels, where both partners share the same field and Graveyard, thus his deck is very likely to get screwed by his partner or his partner is screwed for not using Spell/Trap Cards when they actually need them. [[spoiler:Gongenzaka later gains a new ace monster that can banish Spell/Trap Cards from his Graveyard, yet it is still not suitable in Tag Duels.]]
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