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** [[Anime/Promare Lio Fotia]] (WickedCultured rivals who are the leaders of villainous organizations who later join the protagonist to fight against a LightIsNotGood antagonist from anime created by Creator/StudioTrigger)
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** [[Franchise/TouhouProject Reisen Udongein Inaba]] (extremely powerful red-eyed rabbits with eye-based powers)
to:
** [[Franchise/TouhouProject Reisen Udongein Inaba]] (extremely (Extremely powerful red-eyed rabbits with eye-based powers)
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** [[Franchise/TouhouProject Reisen Udongein Inaba]] (extremely powerful red-eyed rabbits with eye-based powers)
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** [[VideoGame/{{Paladins}} Skye (Paladins)]] (purple-clad {{Stealth Expert}}s who utilize a cloaking device)
to:
** [[VideoGame/{{Paladins}} Skye (Paladins)]] Skye]] (purple-clad {{Stealth Expert}}s who utilize a cloaking device)
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** The [[Franchise/{{Alien}} Xenomorph]] (Dangerous aliens from horror movies who [[Franchise/AlienVsPredator crossed paths multiple times before))
to:
** The [[Franchise/{{Alien}} Xenomorph]] (Dangerous aliens from horror movies who [[Franchise/AlienVsPredator crossed paths multiple times before))before]])
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* [[Manga/JoJosBizarreAdventure Narancia Ghirga]] vs. [[WebAnimation/{{RWBY}} Coco Adel]] (Flamboyant members of a group who both have abilities that allow them to fire projectiles and scan areas for enemies)
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* [[Manga/JoJosBizarreAdventure Narancia Ghirga]] vs. [[WebAnimation/{{RWBY}} Coco Adel]] (Flamboyant members of a group who both have abilities that allow them to fire projectiles and scan areas for enemies)
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* VideoGame/Nier vs. [[VideoGame/ShadowOfTheColossus Wander]] (Warriors from depressing fantasy games who wander across ruined landscapes, fight against monsters of darkness, and unlock seals to aid a magical figure in hope of them helping them save those they care for, with Nier's aid [Weiss] being played straight while Wander's aid [Dormin] [[spoiler:manipulated him into doing his bidding and is responsible for his demise]])
to:
* VideoGame/Nier VideoGame/{{Nier}} vs. [[VideoGame/ShadowOfTheColossus Wander]] (Warriors from depressing fantasy games who wander across ruined landscapes, fight against monsters of darkness, and unlock seals to aid a magical figure in hope of them helping them save those they care for, with Nier's aid [Weiss] being played straight while Wander's aid [Dormin] [[spoiler:manipulated him into doing his bidding and is responsible for his demise]])
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* [[Film/TheLastSamurai Nathan Algren]] vs. [[VideoGame/{{Nioh}} William Adams]] (Western Samurai.)
to:
* [[Film/TheLastSamurai Nathan Algren]] vs. [[VideoGame/{{Nioh}} William Adams]] (Western Samurai.)samurai)
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* [[Franchise/KingdomHearts Vanitas]] vs. [[Franchise/DragonBall Baby]] (Villains who are the only beings that exist of their kind, were created by another person, and desire to spread chaos for the glory of their master)
to:
* [[Franchise/KingdomHearts Vanitas]] vs. [[Franchise/DragonBall Baby]] (Villains who are the only beings that exist of their kind, were created by another person, and desire to spread chaos cause destruction the for the glory of their master)master's power-hungry schemes)
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* [[Franchise/KingdomHearts Vanitas]] vs. [[Franchise/DragonBall Baby]] (Villains who are the only beings that exist of their kind, were created by another person, and desire to spread chaos for the glory of their master)
* [[Franchise/PowerRangers Venjix/Evox]] vs...
** [[WesternAnimation/CodeLyoko XANA]] (Evil computer viruses)
** [[VideoGame/SystemShock SHODAN]] (Same as above)
** [[WesternAnimation/CodeLyoko XANA]] (Evil computer viruses)
** [[VideoGame/SystemShock SHODAN]] (Same as above)
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* [[Franchise/PowerRangers Venjix/Evox]] vs...
** [[WesternAnimation/CodeLyoko XANA]] (Evil computer viruses)
** [[VideoGame/SystemShock SHODAN]] (Same as above)
** [[WesternAnimation/CodeLyoko XANA]] (Evil computer viruses)
** [[VideoGame/SystemShock SHODAN]] (Same as above)
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** [[Manga/DGrayMan Allen Walker]] (Silver-haired demon hunters who have cursed arms)
to:
** [[Manga/DGrayMan Allen Walker]] (Silver-haired demon hunters who have wield a cursed arms)arm of symbiotic tissue to slay their foes, eventually gaining the ability to augment their arm with an array of anti-demon weaponry. Both were born without parents and with a genetic abnormality that connected them to the world of demons, with both eventually venturing to join an Order based around the extermination of demonic forces)
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* [[WebAnimation/RWBY Nora Valkyrie]] vs. [[Manga/JujutsuKaisen Nobara Kugisaki]] (Both are orange-haired girls who attended an academy to learn how to kill the evil creatures in their worlds (Jujutsu Sorcerers killing Curses and Huntsman/Huntresses killing Grimm), having similar personalities which is being sassy, confident, and can get pretty hotheaded, yet jokey and goofy, have some kind of heart symbolism to them (Nora and Nobara having hearts on their hammers and on Nora’s outfits), and are apart of a team of teenagers, their companions in those trios are the black-haired, Intelligent, strategist guy (Megumi and Ren) and a more happy, tough, and dorky type guy who’s like the leader of the team (Yuji and Jaune). Both have similar fighting styles that involve shooting projects, using explosives (Nora has her grenade launcher, Nobara can hit her nails like firing a gun and can use them as crash bombs), and obviously using hammers for melee attacks)
to:
* [[WebAnimation/RWBY [[WebAnimation/{{RWBY}} Nora Valkyrie]] vs. [[Manga/JujutsuKaisen Nobara Kugisaki]] (Both are orange-haired (Orange-haired girls who attended an academy to learn how to kill the evil creatures in their worlds (Jujutsu Sorcerers killing Curses and Huntsman/Huntresses killing Grimm), having similar personalities which is being sassy, confident, and can get pretty hotheaded, yet jokey and goofy, have some kind of heart symbolism to them (Nora and Nobara having hearts on their hammers and on Nora’s outfits), and are apart of a team of teenagers, their companions in those trios are the black-haired, Intelligent, strategist guy (Megumi and Ren) and a more happy, tough, and dorky type guy who’s like the leader of the team (Yuji and Jaune). Both have similar fighting styles that involve shooting projects, using explosives (Nora has her grenade launcher, Nobara can hit her nails like firing a gun and can use them as crash bombs), and obviously using hammers for melee attacks)
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* [[WebAnimation/RWBY Nora Valkyrie]] vs. [[Manga/JujutsuKaisen Nobara Kugisaki]] (Both are orange-haired girls who attended an academy to learn how to kill the evil creatures in their worlds (Jujutsu Sorcerers killing Curses and Huntsman/Huntresses killing Grimm), having similar personalities which is being sassy, confident, and can get pretty hotheaded, yet jokey and goofy, have some kind of heart symbolism to them (Nora and Nobara having hearts on their hammers and on Nora’s outfits), and are apart of a team of teenagers, their companions in those trios are the black-haired, Intelligent, strategist guy (Megumi and Ren) and a more happy, tough, and dorky type guy who’s like the leader of the team (Yuji and Jaune). Both have similar fighting styles that involve shooting projects, using explosives (Nora has her grenade launcher, Nobara can hit her nails like firing a gun and can use them as crash bombs), and obviously using hammers for melee attacks)
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** [[Series/StarTrekTheNextGeneration Worf]], or really other Klingon (aliens from iconic science fiction who follow a code of honor)
to:
** [[Series/StarTrekTheNextGeneration Worf]], or really other Klingon (aliens (Antagonistic aliens from iconic science fiction media who follow a code of honor)
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* [[Series/StarTrekTheNextGeneration Worf]], or really other Klingon (aliens from iconic science fiction who follow a code of honor)
to:
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* [[Series/StarTrekTheNextGeneration Worf]], or really other Klingon (aliens from iconic science fiction who follow a code of honor)
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Changed line(s) 74 (click to see context) from:
** [[Franchise/StreetFighter Necalli]] (Brutish [=MesoAmerican=] warriors who lived on Earth for centuries and long to fight strong opponents from fighting games)
to:
** [[Franchise/StreetFighter Necalli]] (Brutish [=MesoAmerican=] Mesoamerican warriors who lived on Earth for centuries and long to fight strong opponents from fighting games)
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Changed line(s) 74 (click to see context) from:
** [[Franchise/StreetFighter Necalli]] (Brutish MesoAmerican warriors who lived on Earth for centuries and long to fight strong opponents from fighting games)
to:
** [[Franchise/StreetFighter Necalli]] (Brutish MesoAmerican [=MesoAmerican=] warriors who lived on Earth for centuries and long to fight strong opponents from fighting games)
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** [[Franchise/StreetFighter Necalli]] (Brutish Aztec warriors who lived on Earth for centuries and long to fight strong strong opponents from fighting games)
to:
** [[Franchise/StreetFighter Necalli]] (Brutish Aztec MesoAmerican warriors who lived on Earth for centuries and long to fight strong strong opponents from fighting games)
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* [[VideoGame/{{Tekken}} Ogre]] vs...
** [[Franchise/MortalKombat Kotal Khan]] (God-like, Mayincatec bruisers from fighting games, with the former being an anti-heroic, honorable ruler while the latter is a mindless villain)
** [[Franchise/StreetFighter Necalli]] (Brutish Aztec warriors who lived on Earth for centuries and long to fight strong strong opponents from fighting games)
** [[Franchise/MortalKombat Kotal Khan]] (God-like, Mayincatec bruisers from fighting games, with the former being an anti-heroic, honorable ruler while the latter is a mindless villain)
** [[Franchise/StreetFighter Necalli]] (Brutish Aztec warriors who lived on Earth for centuries and long to fight strong strong opponents from fighting games)
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* Franchise/ScoobyDoo vs. [[WesternAnimation/CourageTheCowardlyDog Courage]] (Cowardly dogs who fight against monsters from cartoons, to which they serve as mascots from, and [[WesternAnimation/StraightOuttaNowhereScoobyDooMeetsCourageTheCowardlyDog they have a movie together]])
to:
* Franchise/ScoobyDoo vs. [[WesternAnimation/CourageTheCowardlyDog Courage]] (Cowardly dogs who fight against monsters from cartoons, to which they serve as mascots from, and who [[WesternAnimation/StraightOuttaNowhereScoobyDooMeetsCourageTheCowardlyDog they have a movie together]])crossed paths before]])
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Changed line(s) 286 (click to see context) from:
* Franchise/ScoobyDoo vs. [[WesternAnimation/CourageTheCowardlyDog Courage]] (Cowardly dogs who fight against monsters from cartoons, to which they serve as mascots from)
to:
* Franchise/ScoobyDoo vs. [[WesternAnimation/CourageTheCowardlyDog Courage]] (Cowardly dogs who fight against monsters from cartoons, to which they serve as mascots from)from, and [[WesternAnimation/StraightOuttaNowhereScoobyDooMeetsCourageTheCowardlyDog they have a movie together]])
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Changed line(s) 205 (click to see context) from:
** [[VideoGame/Splatterhouse Rick Taylor]] (Once normal humans who were revived by a manipulative supernatural entity to seek vengeance in hopes of them succumbing to their dark side, with Robbie fighting against Eli's wishes for Robbie to become a cold-blooded killer while Rick gave into the Terror Mask's demands for violence)
to:
** [[VideoGame/Splatterhouse [[VideoGame/{{Splatterhouse}} Rick Taylor]] (Once normal humans who were revived by a manipulative supernatural entity to seek vengeance in hopes of them succumbing to their dark side, with Robbie fighting against Eli's wishes for Robbie to become a cold-blooded killer while Rick gave into the Terror Mask's demands for violence)
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* [[Manga/DemonSlayerKimetsuNoYaiba Tanjiro Kamado]] vs. [[Manga/JojosBizarreAdventurePhantomBlood Johnathon Joestar]] (Manga protagonists that have lost family at the hands of the BigBad[[note]]Tanjiro's mother and younger siblings (except for Nezuko) were killed by Muzen, while Johnathon's dog and father were killed by Dio.[[/note]] and start training in a fighting style based on sunlight that's adverse to their enemies)
to:
* [[Manga/DemonSlayerKimetsuNoYaiba Tanjiro Kamado]] vs. [[Manga/JojosBizarreAdventurePhantomBlood Johnathon Joestar]] (Manga protagonists that have lost their remaining family at the hands of the BigBad[[note]]Tanjiro's mother and younger siblings (except for Nezuko) were killed by Muzen, while Johnathon's dog and father were killed by Dio.[[/note]] Dio[[/note]] and start training in a fighting style based on sunlight that's adverse to their enemies)
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* [[Manga/DemonSlayerKimetsuNoYaiba Tanjiro Kamado]] vs. [[Manga/JojosBizarreAdventurePhantomBlood Johnathon Joestar]] (Manga protagonists that have lost family at the hands of the BigBad[[note]]Tanjiro's mother and younger siblings (except for Nezuko) were killed by Muzen, while Johnathon's dog and father were killed by Dio.[[/note]] and start training in a fighting style based on sunlight that's adverse to their enemies)
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''Death Battle'' suggestions for one-on-one matches with a common link:
to:
''Death Battle'' suggestions for one-on-one matches with a common link:link, sorted from N-Z:
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*** '''N-Z''
to:
*** '''N-Z'''''N-Z'''
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** '''One-on-one with a common theme'''
to:
** '''One-on-one [[WMG/DeathBattleOneOnOneMatchSuggestions One-on-one with a common theme'''theme]]
*** [[WMG/DeathBattleOneOnOneMatchSuggestionsAToM A-M]]
*** '''N-Z''
*** [[WMG/DeathBattleOneOnOneMatchSuggestionsAToM A-M]]
*** '''N-Z''
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''Death Battle'' suggestions for one-on-one matches with a common link:
* [[WMG/DeathBattle Main Page]]
* [[WMG/DeathBattleBackstories Backstories]]
* [[WMG/DeathBattleRecurringTrends Recurring Trends]]
* [[WMG/DeathBattleSuggestions Suggestions]]
** '''One-on-one with a common theme'''
** [[WMG/DeathBattleThemedMatchSuggestions Groups of combatants with a common theme]]
** [[WMG/DeathBattleBattleRoyaleAndTeamBattleSuggestions Battle Royales/Team Battles]]
** [[WMG/DeathBattleJokeSuggestionsAndBadIdeas Joke Suggestions/Bad Ideas for a DB]]
** [[WMG/DeathBattleSuggestionsReturningCombatants Returning Combatants]]
** [[WMG/DeathBattleOriginalTrackSuggestions Original Tracks]]
A few things to keep in mind:
* Remember that they should have at least some common factor. Even the Starscream vs. Rainbow Dash had one; both being popular high flyers in their toylines in Hasbro. Also, no {{fanon}} interpretations of characters.
* No {{creepypasta}}. They have too many unknowns to be qualified combatants, and Death Battle is known for [[ShownTheirWork showing their research]].
* Characters who run on the RuleOfFunny are generally frowned upon. With no established limits, any scientific limits would be random. However, this doesn't really apply if that is the entire point; if you have a "just for fun" type match up, put it in the Jokes Battles folder.
* No {{Memetic Badass}}es after Chuck Norris and Segata Sanshiro (that match-up's enough, thanks!). The fun of the meme is kind of ruined when the show reveals and proves that they're not nearly as badass as all the jokes and facts say. [[spoiler:And besides, the aforementioned match ended in an apocalyptic draw]].
* If you see several characters carrying the same consistent theme in this page, be sure to move them [[WMG/DeathBattleThemedMatchSuggestions here]].
----
* [[WMG/DeathBattle Main Page]]
* [[WMG/DeathBattleBackstories Backstories]]
* [[WMG/DeathBattleRecurringTrends Recurring Trends]]
* [[WMG/DeathBattleSuggestions Suggestions]]
** '''One-on-one with a common theme'''
** [[WMG/DeathBattleThemedMatchSuggestions Groups of combatants with a common theme]]
** [[WMG/DeathBattleBattleRoyaleAndTeamBattleSuggestions Battle Royales/Team Battles]]
** [[WMG/DeathBattleJokeSuggestionsAndBadIdeas Joke Suggestions/Bad Ideas for a DB]]
** [[WMG/DeathBattleSuggestionsReturningCombatants Returning Combatants]]
** [[WMG/DeathBattleOriginalTrackSuggestions Original Tracks]]
A few things to keep in mind:
* Remember that they should have at least some common factor. Even the Starscream vs. Rainbow Dash had one; both being popular high flyers in their toylines in Hasbro. Also, no {{fanon}} interpretations of characters.
* No {{creepypasta}}. They have too many unknowns to be qualified combatants, and Death Battle is known for [[ShownTheirWork showing their research]].
* Characters who run on the RuleOfFunny are generally frowned upon. With no established limits, any scientific limits would be random. However, this doesn't really apply if that is the entire point; if you have a "just for fun" type match up, put it in the Jokes Battles folder.
* No {{Memetic Badass}}es after Chuck Norris and Segata Sanshiro (that match-up's enough, thanks!). The fun of the meme is kind of ruined when the show reveals and proves that they're not nearly as badass as all the jokes and facts say. [[spoiler:And besides, the aforementioned match ended in an apocalyptic draw]].
* If you see several characters carrying the same consistent theme in this page, be sure to move them [[WMG/DeathBattleThemedMatchSuggestions here]].
----
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* [[Franchise/{{Pokemon}} N]] vs. [[Franchise/YuGiOh Marik Ishtar]] (Royal commanders of monsters who first fight against the protagonist but later aid them)
* [[VideoGame/GuiltyGear Nagoriyuki]] vs...
** [[VideoGame/{{Castlevania}} Alucard]] (Vampiric swordsmen with heavy ties to the antagonists of their franchises [Happy Chaos for Nagoriyuki, Dracula for Alucard])
** [[VideoGame/BlazBlue Hakumen]] (Extremely powerful swordsmen dressed in white outfits and eyeless masks from [[Creator/ArcSystemWorks ArcSys]] fighting games)
* [[Manga/OnePiece Nami]] vs. [[VideoGame/FinalFantasyVII Yuffie]] (Kind-hearted and noble thieves that were originally antagonistic towards a small group of heroes, but eventually joining with said group in order to go on many adventures)
* [[Film/TheLastSamurai Nathan Algren]] vs. [[VideoGame/{{Nioh}} William Adams]] (Western Samurai.)
* [[ComicBook/TheBlackKnight Nathan Garrett]] vs. [[VideoGame/FireEmblemRadiantDawn General Zelgius]] (villains with enchanted swords and the label of {{black knight}})
* [[VideoGame/MeltyBlood Neco-Arc]] vs. [[VideoGame/{{Undertale}} Temmie]] (Strange yet comedic creatures with cat-like traits who break the fourth wall)
* [[WesternAnimation/DarkwingDuck Negaduck]] vs. [[WesternAnimation/KungFuPanda2 Lord Shen]] (Evil avian rivals)
* [[Manga/NegimaMagisterNegiMagi Negi Springfield]] vs. [[Anime/LittleWitchAcademia Akko Kagari]] (Anime mages inspired by Literature/HarryPotter)
* VideoGame/Nier vs. [[VideoGame/ShadowOfTheColossus Wander]] (Warriors from depressing fantasy games who wander across ruined landscapes, fight against monsters of darkness, and unlock seals to aid a magical figure in hope of them helping them save those they care for, with Nier's aid [Weiss] being played straight while Wander's aid [Dormin] [[spoiler:manipulated him into doing his bidding and is responsible for his demise]])
* The [[Franchise/ResidentEvil Nemesis T-Type]] vs...
** [[Franchise/SilentHill Pyramid Head]] (Humanoid, brutish monsters with large weapons from two of the most beloved horror video game series of all time, with Nemesis wielding ranged weapons and mutating throughout its appearances while Pyramid Head wields a melee weapon and stays largely the same)
** The [[VideoGame/BioShock Big Daddy]] (Large, scary monsters who don't speak much, were created through genetic tampering, and designed for a specific goal with opposite relations to a certain group [The Big Daddies being created to protect the Little Sisters while the Nemesis T-Type was created to hunt down and kill members of S.T.A.R.S.])
* [[Toys/{{Jewelpet}} Nephrite]] vs. [[VideoGame/MetalGearSolid Sniper Wolf]] (canine-themed snipers)
* [[VideoGame/{{Neptunia}} Neptune/Purple Heart]] vs...
** Series/KamenRiderExAid (Clumsy and absentminded caretakers with two personalities whose love of retro gaming is exceptionally relevant, as their job is keeping the peace in a world filled with threats related to that very subject)
** [[Franchise/{{Persona}} Yu Narukami]] (Sword-wielding JRPG protagonists who draw power from their connection of others, and lead a team of heroes with similar powers to them)
* [[Manga/JoJosBizarreAdventure Narancia Ghirga]] vs. [[WebAnimation/{{RWBY}} Coco Adel]] (Flamboyant members of a group who both have abilities that allow them to fire projectiles and scan areas for enemies)
* [[Franchise/{{Pokemon}} Necrozma]] vs. [[Webcomic/MobPsycho100 Toichiro Suzuki]] ([[PowerParasite Power-stealing]] antagonists who seek to throw their worlds into chaos)
* [[VideoGame/DevilMayCry Nero]] vs...
** [[Manga/DGrayMan Allen Walker]] (Silver-haired demon hunters who have cursed arms)
** ComicBook/{{Hellboy}} (Snarky, revolver-wielding anti-heroes who possess both a RedRightHand and a demonic heritage)
** [[VideoGame/FinalFantasyXV Noctis Lucis Caelum]] (Anti-heroic heroes who wield swords longside magic and fight against their evil fathers)
** [[VideoGame/FinalFantasyVII Vincent Valentine]] (anti-heroic, BadassLongcoat-clad revolver users who wield demonic power)
* [[ComicBook/{{SHIELD}} Nick Fury]] vs...
** ComicBook/JudgeDredd ([[CoolOldGuy Elderly]], {{lawful neutral}} operatives of not-so-nice government institutions who outwit and overpower enhanced individuals with guile, experience, and basic weaponry)
** [[Franchise/{{Batman}} Commissioner Gordon]] (Marvel vs. DC fight of leaders of human forces who aid heroes)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Nightmare Moon]] Vs. [[VideoGame/PrimalRage Vertigo]] (moon-dwelling maniacs)
* [[VideoGame/NightsIntoDreams NiGHTS]] vs. WesternAnimation/PeterPan (Flying, playful figures who take children to mysterious realms to fight off against evil forces)
* [[VideoGame/FinalFantasyXV Noctis Lucis Caelum]] vs...
** [[VideoGame/NierAutomata 2B]] (Stoic protagonists who wear black and are expert weapon masters)
** [[VideoGame/FireEmblemAwakening Chrom]] (Sword-wielding royalty who lead a group of four people on grand adventures)
* [[VideoGame/HeavyRain Norman Jayden]] vs. [[VideoGame/DeadlyPremonition Francis York Morgan]] (FBI agents from video games)
* [[VideoGame/PowerBlade NOVA]] vs. [[VideoGame/SkeletonBoomerang Hunter]] (Platform game protagonists who fight with boomerangs)
* [[Anime/KillLaKill Nui Harime]] vs...
** [[Manga/FistOfTheNorthStar Jagi]] (Evil adoptive siblings that serve as personal rivals to the protagonists [Jagi for impersonating Kenshiro and manipulating Shin, Nui for killing Ryuko's father] who are scarred by the protagonist in some form [with Jagi having his faceplate and helm to cover the disfiguring wound Kenshiro gave him while Nui having her prosthetic arms following Ryoko cutting them off])
** [[VideoGame/{{Darkstalkers}} Baby Bonnie Hood]] (Young girls who look sweet and innocent, but are actually [[TheFakeCutie two of the most psychotic and dangerous characters of their respective series]])
* [[Literature/CthulhuMythos Nyarlathotep]] vs. [[Literature/TheDarkTower Walter Padick/Randall Flagg]] (Immortals whose actions have cemented them as the overall BigBad of their respective franchises, have taken many [[IHaveManyNames names]] and faces over the course of history, commit terrible actions against humanity [[ForTheEvulz simply of the sake of it]], and who are really just a minion to their franchise's GreaterScopeVillain)
* [[ComicBook/{{Asterix}} Obelix]] vs...
** [[ComicBook/{{Suske en Wiske}} Jerome]] (The strongest characters in both worlds, who also originate from different time periods)
** [[VideoGame/MetalGearRisingRevengeance Senator Armstrong]] (Same as above)
* [[WesternAnimation/StevenUniverse Obsidian]] vs. [[VideoGame/MarioAndLuigiPaperJam Shiny RoboBowser]] (giant fusion forms featured in final battles. Obsidian is used against a final boss while Shiny [=RoboBowser=] is one)
* [[Manga/MyHeroAcademia Ochako Uraraka]] vs...
** [[VideoGame/GravityRush Kat]] (Female superheroes who control gravity)
** [[Manga/JoJosBizarreAdventure Koichi Hirose]] (Young school students with power over gravity)
** [[Animation/BoBoiBoy Yaya Yah]] (Same as above, but both are pink, feminine {{NiceGirl}}s)
* [[VideoGame/AstralChain Officer Howard]] vs...
** [[VideoGame/XenobladeChronicles2 Rex]] (Protagonists from modern Creator/Nintendo video games with a blue color scheme who fight alongside a construct)
** [[VideoGame/ChaosLegion Sieg Wahrheit]] (hack-and-slash protagonists whose fighting styles rely on swords and summoned Legions)
* ComicBook/OldManLogan vs. [[ComicBook/TeenageMutantNinjaTurtlesTheLastRonin The Last Ronin]] (BadFuture versions of mutant superheroes who are the last living member of their team)
* [[ComicBook/{{Invincible}} Omni-Man]] vs...
** [[Manga/BakiTheGrappler Yujiro Hanma]] (Abusive fathers who are also the strongest beings in their respective settings)
** [[Franchise/DragonBall Bardock]] (Superhuman warriors who are the fathers of the main protagonist who were originally villainous figures who worked for their tyrannical race before they betrayed them)
* [[Manga/{{Naruto}} Orochimaru]] vs. [[Manga/SoulEater Medusa Gorgon]] (Snake-themed villains from manga/anime who have major connections to a protagonist)
* [[Manga/MyHeroAcademia Overhaul]] vs...
** [[Manga/OnePiece Trafalgar Law]] (Crime lords from Magazine/ShonenJump manga/anime who can disassemble and reassemble objects, with the former being a vicious, cruel figure who never redeemed himself while the latter eventually became a hero)
** [[Franchise/ResidentEvil Albert Wesker]] (Cruel antagonists who lead evil organizations, can kill with just a touch, preform experiments on others, mutated throughout their appearances, and desire power, with the latter being loving towards his boss while the latter killed his boss to get ahead in his schemes)
* [[Franchise/{{Pokemon}} Palkia]] vs. [[Franchise/DragonBall Omega Shenron]] (Two dragon-like lifeforms who were created as higher beings as part of a group, made to do certain jobs. However, they usually go after their "comrades", and were eventually put down via what is the opposite of their powers)
* [[Franchise/{{Pokemon}} Palossand]] vs. [[VideoGame/MegaManBattleNetwork3WhiteAndBlue DesertMan.EXE]] (living sand creatures consisting of a head and two arm-like appendages)
* [[VideoGame/KidIcarusUprising Palutena]] vs...
** [[Franchise/SuperMarioBros Rosalina]] (Goddesses from Nintendo video game series who rule over a realm in a non-earthly realm [Rosalina ruling over the Comet Observatory in space with Palutena ruling Skyworld] who protect a race of divine beings [The Lumas for Rosalina, the angels for Palutena])
** [[WesternAnimation/MyLittlePonyFriendshipIsMagic Princess Celestia]] ([[GodOfGood Heroic goddesses]] who can [[LightIsGood control light]] and [[TheGadfly enjoy messing with their subjects, but still mean well]])
** [[Franchise/TheLegendOfZelda Midna]] (Goddesses from Creator/Nintendo games who live in realms reflecting their opposite abilities, with Palutena [who has heavenly abilities] living in a realm of light while Midna [who has abilities based on shadows] living in a realm of darkness)
* [[Manga/JoJosBizarreAdventure Pannacotta Fugo]] vs...
** [[WesternAnimation/MiraculousLadybug Chat Noir]] (blonde pretty boys with the power of untold destruction)
** [[Manga/AkameGaKill Akame]] (Assassins who wield powerful toxins that can easily kill their targets, started out as promising children before their downfall who unlocked special abilities after accepting their faults)
* [[WesternAnimation/SpongeBobSquarePants Patrick Star]] vs...
** [[WesternAnimation/TheAmazingWorldOfGumball Richard Watterson]] (pink FunnyAnimal, FatIdiot, lazy and unemployed ManChild from cartoons)
** [[WesternAnimation/EdEddNEddy Ed]] (Generally friendly and unintelligent cartoon characters with impressive strength)
* [[WebAnimation/{{RWBY}} Penny Polendina]] vs. [[Series/PowerRangersOperationOverdrive Mack Hartford]] (Young-kind heroes from a popular series, but not a well-liked series [[spoiler:who turn out to be an android made by their father [[HumanityEnsues and became human later on]]]] and has ties with relics.
* Franchise/PercyJackson vs. [[WesternAnimation/StevenUniverse Lapis Lazuli]] (Water manipulators)
* [[WesternAnimation/MickeyMouse Pete]] vs. [[ComicStrip/{{Popeye}} Bluto]] (Brutish rivals of animated protagonists who seek their lover's affection but is always defeated by their rivals)
* ComicStrip/ThePhantom vs. Radio/TheShadow (sneaky, mysterious, often gunslinging pulp proto-superheroes)
* [[VideoGame/{{Overwatch}} Pharah]] vs...
** [[VideoGame/{{Paladins}} Drogoz]] (FlyingFirepower characters from [[HeroShooter Hero Shooters]] who use jetpacks and rocket launchers to rain down death from above)
** [[VideoGame/TeamFortress2 The Soldier]] (Soldiers who utilize rockets to attack their foes from rivalling team-based shooters)
* [[WesternAnimation/{{Chaotic}} Phelphor]] vs. [[Franchise/CthulhuMythos Cthulhu]] (monsters with MindControl powers who originate from the sea)
* [[Franchise/MarvelCinematicUniverse Phil Coulson]] vs. [[Franchise/{{Batman}} Commissioner Gordon]] (Marvel vs. DC fight of leaders of human forces who aid heroes)
* [[VideoGame/{{Paladins}} Pip]] vs. [[VideoGame/{{Gigantic}} Uncle Sven]] (HeroShooter support characters who fight using potions and alchemy)
* [[VideoGame/AtelierSophieTheAlchemistOfTheMysteriousBook Plachta]] vs. [[Franchise/{{Persona}} Sophia/Sophie]] (Beings resembling young girls who have a mysterious past and take residence inside an object owned by the game's protagonist)
* [[VideoGame/ShovelKnight Plague Knight]] vs...
** [[VideoGame/LeagueOfLegends Ziggs]] (Short but formidable foes who utilize explosives in many different ways using science.)
** [[VideoGame/{{Skylanders}} Pop Fizz]] (Crazy short potion using foe who use their potions in different and creative ways)
* [[VideoGame/GuiltyGear Potemkin]] vs. [[VideoGame/BlazBlue Iron Tager]] (Large grapplers with mechanical gauntlets who serve as soldiers from [[Creator/ArcSystemWorks ArcSys]] fighting games)
* [[WesternAnimation/TheRenAndStimpyShow Powdered Toast Man]] vs. [[WesternAnimation/RockosModernLife Really Really Big Man]] (parody superheroes)
* The Franchise/{{Predator}} VS...
** The [[Franchise/{{Alien}} Xenomorph]] (Dangerous aliens from horror movies who [[Franchise/AlienVsPredator crossed paths multiple times before))
** [[VideoGame/StarCraft Zeratul]] (honor-bound alien warriors who can turn invisible)
** [[Franchise/StarWars The Mandalorian]] (Space-travelling bounty hunters who wear masks and armor, use high-tech weaponry, and follow a code of honor)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Princess Luna]] vs...
** [[WesternAnimation/RiseOfTheGuardians Pitch Black]] (wielders of darkness who can enter peoples' dreams)
** [[VideoGame/MegaManX8 Dark Mantis]] (another wielder of darkness. Luna may be able to use his weapon too.)
** [[Franchise/{{Kirby}} Dark Matter]] (a [[RuleOfThree third]] darkness-based being)
* [[VideoGame/Dota2 Pudge]] vs. [[VideoGame/{{Overwatch}} Roadhog]] ({{Fat Bastard}}s who use a hook on a chain as a weapon)
* ComicBook/ThePunisher vs...
** ComicBook/JudgeDredd (JudgeJuryAndExecutioner)
** [[VideoGame/{{Overwatch}} Soldier: 76]] (former military heroes turned violent vigilante men after life-changing tragedy)
* [[VideoGame/XenobladeChronicles2 Pyra]] vs. [[Franchise/FateSeries Nero]] (Female swordfighters dressed in red who are bound to the soul of their master, with their masters also fighting in wars and seeking things that are magical [Rex seeking Elysium while Hakuno seeks the Holy Grail)
* [[VideoGame/TeamFortress2 The Pyro]] vs...
** [[Franchise/{{Batman}} Firefly]] (flamethrower-wielding pyromaniacs)
** [[VideoGame/{{Overwatch}} Mei]] (Fire vs. ice matchup of characters with similar roles from rival team-based shooters, with the former being a crazed maniac who has the mind of a child while the latter is a caring, brilliant scientist)
** [[VideoGame/{{Overwatch}} Roadhog]] (Masked criminals that take no issue with causing carnage, with the former using mainly ranged weapons while the latter uses melee attacks)
* [[WebAnimation/{{RWBY}} Pyrrha Nikos]] vs...
** [[ComicBook/TheMightyThor Lady Sif]] (formidable swordswomen who're among the greatest warriors in their respective realms)
** [[Manga/JoJosBizarreAdventure Noriaki Kakyoin]] (Red-headed members of a team that they are considered the brains of, which both having lonely pasts and were [[spoiler:eventually killed by major antagonists]])
* [[WebAnimation/{{RWBY}} Qrow Branwen]] vs...
** [[Manga/MyHeroAcademia Shota Aizawa]] (Badass teachers, that both look like homeless people)
** [[Manga/SoulEater Spirit Albarn]] (presumably wielded by either Stein or Lord Death) (Familial figures to teenage female scythe-wielding protagonists, who also use scythes, or in Spirits' case ''is'' the scythe)
* [[Franchise/MortalKombat Quan Chi]] vs...
** [[VideoGame/{{Darkstalkers}} Jedah Dohma]] ({{Big Bad}}s attempting to summon a GodOfEvil)
** ComicBook/{{Taskmaster}} (villainous characters who can copy the fighting styles of others)
* [[WesternAnimation/DuckDodgers Queen Tyr'ahnee]] vs. [[WesternAnimation/MyLifeAsATeenageRobot Queen Vexus]] (evil "queens")
* [[VideoGame/BlazBlue Rachel Alucard]] vs. [[Franchise/ShinMegamiTensei Alice]] (Powerful, unholy entities with the appearance of young girls in fancy clothes.)
* [[Anime/KillLaKill Ragyo Kiryuin]] vs...
** [[Manga/SoulEater Medusa Gorgon]] (MagnificentBastard villainesses infamous for being [[AbusiveParents abusive mothers]])
** [[VideoGame/PokemonSunAndMoon Lusamine]] (BigBad [[ArchnemesisMom mothers]] who are AxCrazy, borderline obsessed with alien lifeforms from another dimension [the Life Fibres and the Ultra Beasts respectively], wear variants of said lifeforms to become even more powerful, and are opposed by both the main protagonists and their own daughters)
* [[WesternAnimation/XiaolinShowdown Raimundo Pedrosa]] vs. [[WesternAnimation/{{Ninjago}} Lloyd Garmadon]] (Chosen heroes from teams of Eastern-themed elemental warriors who become the leaders of their teams despite first turning evil.)
* [[Franchise/MortalKombat Rain]] vs...
** [[VideoGame/FireEmblemFates Corrin]] (People who were born of nobility but became separated from them soon after birth, wield water as their primary means of attack, were the main player in a civil war, and both have an unusual heritage which puts them above others [Corrin being half-dragon and Rain being a demigod])
** [[Manga/JoJosBizarreAdventure Weather Report]] (Children of powerful families who were separated from them at birth with arrogant demeanors [by default with Rain, as [[spoiler:Wes Bluemarine]] with Weather Report], [[spoiler:seek to avenge loved ones who were killed at the hands of major antagonists of their series [Shao Khan and Argus for the former, Enrico Pucci for the latter]]], have the ability to control water and electricity, are named after musicians [Music/Prince for the former, Music/WeatherReport for the latter])
** [[Franchise/{{Pokemon}} Greninja]] (Hydrokinetic ninjas)
* [[Franchise/StreetFighter Rainbow Mika]] vs. [[Franchise/TheKingOfFighters Ángel]] (Sensual female wrestlers from fighting games whose stories involve corrupt organizations who host tournaments)
* [[Literature/{{Dragonlance}} Raistlin Majere]] vs. [[Literature/TheElricSaga Elric of Melniboné]] (Sickly albino sorcerers)
* [[WesternAnimation/RandyCunninghamNinthGradeNinja Randy Cunningham]] vs...
** [[Series/PowerRangersSamurai Jayden Shiba]] (teenage high-school heroes clad in red and black suits based on Japanese warriors [Ninja and Samurai respectively] who inherited their suits from another and protect their hometowns from the forces of evil)
** [[WesternAnimation/MiraculousLadybug Ladybug]] (teenaged high school heroes that wear black and red tight suits and set out to save innocent people who have been corrupted by dark magic from the BigBad)
* [[Manga/FistOfTheNorthStar Raoh]] vs...
** [[WebComic/OnePunchMan Garou]] (Former pupils of great masters who became powerful, anti-villainous martial artists who serve as the antithesis to their protagonists, seek to band their worlds together under a common cause [Raoh to unite the people of the world under his command to restore order, Garou to unite the world's heroes to fight against him] and to become even more powerful than they already are, have an honorable side, betrayed their masters, and can copy others' techniques)
** [[Manga/YuYuHakusho Younger Toguro]] (Muscular, powerful rivals to heroes from classic manga/anime who seek to fight strong opponents and are honorable despite their status as villains)
** [[Manga/{{Berserk}} Nosferatu Zodd]] (Same as above)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rarity]] vs...
** [[VideoGame/MegaManX2 Crystal Snail]] ([[GemstoneAssault crystal users]])
** [[Toys/{{Jewelpet}} Garnet]] (This fashionista cat has a similar personality to Rarity. They are part of their respective shows' main groups, and both of them have also been corrupted with dark magic at certain points.)
** [[VideoGame/ThemsFightinHerds Velvet]] ([[GemstoneAssault gem magic]] vs. [[AnIcePerson ice magic]]; plus Velvet originated as an expy of Rarity)
* ComicBook/RasAlGhul vs...
** [[ComicBook/CaptainAmerica Baron Zemo]] (Marvel vs. DC fight of terrorists and assassins who lead organizations dedicated to these causes who stand in opposition to major protagonists)
** The [[ComicBook/IronMan Mandarin]] (same as above, but with both villains also having an Asian aesthetic and using magical techniques)
** [[WesternAnimation/AvatarTheLastAirbender Fire Lord Ozai]] (Leaders of evil, Asian-inspired organizations who use their daughters [Talia for Ra's, Azula for Ozai] as minions who utilize magic)
** [[Manga/JoJosBizarreAdventure Will Anthonio Zeppeli]] (Mentors to the protagonist who dedicate their lives studying a technique used to obtain eternal life, with the former being a villain who embraces the technique while the latter is a hero who fights against it)
** [[VideoGame/AssassinsCreedII Ezio Auditore]] (Master assassins and members of organizations who have done as such for centuries)
* [[Franchise/StreetFighter Rashid]] vs. [[Franchise/TheKingOfFighters Shun'ei]] (Capcom vs SNK matchup, the "new generation" heroes with a fondness for technology who use elemental powers and have an old mentor.)
* [[Franchise/{{Metroid}} Raven Beak]] vs...
** [[ComicBook/{{Invincible}} Thragg]] (Warlords who lead a group of a species related to the protagonist of each work)
** [[Franchise/{{Halo}} The Didact]] (Alien warlords who seek to conquer other planets, wear armor, and [[spoiler:mutate themselves to increase their strength]])
* [[Franchise/{{Pokemon}} Rayquaza]] vs. [[Franchise/FinalFantasy Bahamut]] (Draconic deities among the most powerful among their group of monsters who lend their power only to those who are worthy of it, utilize a wide variety of elemental abilities, and are often associated with meteors [Rayquaza is often tasked with destroying one in various games it's in and Bahamut was inside a meteor that it emerged from])
* [[VideoGame/{{Overwatch}} Reaper]] vs...
** [[VideoGame/{{Paladins}} Androxus]] (Dark and edgy masked gunslingers who are obsessed with death and excel in close-quarters combat)
** [[Franchise/MortalKombat Noob Saibot]] (Edgy, vengeful assassins dressed in black outfits and masks who have shadow-based magical abilities)
* ComicBook/RedSkull vs...
** [[Manga/JoJosBizarreAdventure Rudol von Stroheim]] (superpowered Nazis from comics)
** [[Franchise/{{Batman}} Black Mask]] (supervillains with a SkullForAHead)
** ComicBook/RasAlGhul (Supervillainous leaders of powerful organizations, with the former pursuing technology and a modern hegemonic view while the latter weaponized traditional assassination methods and magic to aid others in their goals)
* [[VideoGame/XenobladeChronicles2 Rex]] vs...
** [[VideoGame/TalesOfZestiria Sorey]] (Protagonists from fantasy [=RPGs=] whose liking towards ruins caused them to bond with a mysterious girl and fight alongside elemental constructs)
** [[Franchise/ShinMegamiTensei Nanashi]] (Once ordinary looters from [=RPGs=] who joined forces with a spiritual entity after originally dying to an evil, hegemonic figure [Jin for Rex, Adremelech for Nanashi] who summon other spiritual entities to attack and have green markings to show their bond)
** [[VideoGame/FinalFantasyV Bartz Klauser]] (Brown-haired, sword-wielding protagonists from [=RPGs=] who became legendary heroes [despite their original status as orphans] by defeating an originally ordinary entity who became corrupted y dark influence into becoming a god-like figure)
* [[Franchise/TouhouProject Reimu Hakurei]] vs. [[VideoGame/PuyoPuyo Arle Nadja]] (Cute yet powerful female mages who are kind to others and fight against dark entities)
* [[VideoGame/{{Overwatch}} Reinhardt]] vs...
** [[VideoGame/{{Paladins}} Fernando]] (Knights in futuristic PoweredArmor who use large, rectangular energy shields)
** [[WebAnimation/{{RWBY}} Nora Valkyrie]] (Hammer-wielding powerhouses with eccentric personalities that may or may not just be fronts to hide their past trauma)
** [[VideoGame/GranblueFantasy Vaseraga]] (Large knights with equally large weapons who used to command a unit of soldiers until they lost command over them in the same battle that they [[HandicappedBadass received a crippling injury]] [Reinhart losing an eye while Vaseraga was paralyzed from poison], to which they were recruited by an organization that gave them the augments required to allow them to keep fighting, with Reinhardt honoring the sacrifice his mentor made [having died in the battle that took Reinhardt's eye] while Vaseraga is haunted by his failure to protect his crew)
* [[Franchise/{{Pokemon}} Reshiram]] vs. [[Franchise/YuGiOh Blue-Eyes White Dragon]] (Legendary white dragon OlympusMons who can [[FusionDance fuse together]] with other, similar dragons to become even more powerful)
* [[VideoGame/MetalGear Revolver Ocelot]] vs. [[Franchise/KingdomHearts Xigbar]] ([[TheGunslinger Gunslingers]] who lose a part of their body to a swordsman during a battle, and act as TheDragon to the BigBad [[spoiler:while in truth actually being [[TheManInFrontOfTheMan the true mastermind behind everything]]]])
* [[Series/TheWalkingDead Rick Grimes]] vs. [[VideoGame/TheLastOfUs Joel Miller]] (anti-heroic, undead-battling {{Papa Wol|f}}ves from post-apocalyptic settings)
* [[WesternAnimation/RickAndMorty Rick Sanchez]] vs. WesternAnimation/MrPickles (ExtremeOmnisexual [[NominalHero Nominal Heroes]] from shows on Creator/AdultSwim, both of whom have young companions who act as [[MoralityPet Morality Pets]] and [[Memes/RickAndMorty an association]] [[TrademarkFavoriteFood with pickles]])
* [[VideoGame/JustCause Rico Rodriguez]] vs. [[VideoGame/BionicCommando Nathan "Radd" Spencer]] (grappling hook combatants)
* [[Franchise/{{Metroid}} Ridley]] vs...
** [[Franchise/{{Castlevania}} Death]] (major recurring bosses of the two TropeNamers of the {{Metroidvania}} genre. Both become final bosses in rare cases, and both killed fighters in trailers leading up to the release of ''VideoGame/SuperSmashBrosUltimate'')
** [[VideoGame/MegaManX Vile]] (Recurring antagonists in video game series starting arm cannon-wielding heroes that [[TheDragon serve the main antagonist as their right-hand instead of being final bosses]], themselves being violent, sadistic criminals with a purple color scheme)
** [[WesternAnimation/Ben10 Vilgax]] (Vicious alien warlords who [[WouldHurtAChild have no issue harming children]] or their loved ones)
* [[WesternAnimation/MuchaLucha Rikochet]] vs. [[WesternAnimation/ElTigreTheAdventuresOfMannyRivera El Tigre]] (Mexican child heroes)
* [[Manga/BlueExorcist Rin Okumura]] vs...
** [[WebAnimation/{{RWBY}} Adam Taurus]] ([[HornedHumanoid Horned]] swordsmen who are rejected by the worlds they live in due to their species)
** [[Manga/FireForce Shinra Kusakabe]] (Fire manipulators with a devil-theming)
* [[Manga/JoJosBizarreAdventure Risotto Nero]] vs. [[Franchise/MortalKombat Skarlet]] (Assassins who specialize in weaponizing their targets' blood)
* [[Franchise/RatchetAndClank Rivet]] vs. [[VideoGame/CrashBandicoot Tawna Bandicoot]] (Modern [=PlayStation=] game heroines who are the female counterparts of an animalistic hero from another dimension who fight against alternate counterparts of evil doctors)
* Myth/RobinHood vs...
** Myth/KingArthur (the classical heroes of legend)
** Myth/WilliamTell (Mythological archers known for their ludicrous [[SplittingTheArrow arrow-shooting]] [[WilliamTelling skills]])
* [[Series/LazyTown Robbie Rotten]] vs. [[WesternAnimation/PAWPatrol Mayor Humdinger]] (Two recurring comical purple-clad villains of popular kids' shows. Both of them also have blue-clad heroes opposing them)
* [[ComicBook/AllNewGhostRider Robbie Reyes]] vs...
** Series/KamenRiderGhost (Teens with dreams of a good life in the future involving a family member, until one day they are suddenly killed at random but come back with due to an outside force reviving them giving them super spiritual powers, and in this new form they are equipped with a blade, black jacket, and go by a title with the word "ghost" in it, and are now on a mission to stop anybody who preys on the weak)
** [[VideoGame/Splatterhouse Rick Taylor]] (Once normal humans who were revived by a manipulative supernatural entity to seek vengeance in hopes of them succumbing to their dark side, with Robbie fighting against Eli's wishes for Robbie to become a cold-blooded killer while Rick gave into the Terror Mask's demands for violence)
* [[ComicBook/GuardiansOfTheGalaxy Rocket Raccoon]] vs...
** VideoGame/SlyCooper (raccoon heroes)
** [[Franchise/LiloAndStitch Stitch]] (Genetic Experiments with expert piloting skills and precision with guns)
* [[VideoGame/FatalFury Rock Howard]] vs...
** [[Manga/JoJosBizarreAdventure Trish Una]] (Heroic children of gang leaders who are adopted by heroes and fight using melee attacks)
** [[Franchise/MortalKombat Cassie Cage]] (Children of major fighting game protagonists [albeit an adopted one, in Rock's case] who become the face of a "next-generation" cast)
* [[Literature/TheDarkTower Roland Deschain]] vs...
** [[Manga/BlackCat Train Heartnet]] (Masterful Gunslingers with a dark past and a preference for revolvers.)
** ComicBook/JonahHex (The most famous gunslinger in literature VS the most famous gunslinger in comics. Both are war veterans who have dealt with the supernatural, survived in post-apocalyptic worlds and, occasionally, gone through time travel.)
* [[Manga/JoJosBizarreAdventure Rohan Kishibe]] vs...
** [[VideoGame/{{Scribblenauts}} Maxwell]] (Users of immensely powerful, writing-centric reality-warping abilities)
** [[Franchise/{{Persona}} Yusuke Kitagawa]] (Stoic and mature yet eccentric artists who fight with the aid of {{FightingSpirit}}s)
* [[Franchise/KingdomHearts Roxas]] vs. [[VideoGame/MegaManX Axl]] (Inhuman humanoids who were once integral parts of antagonistic organizations before leaving due to the organization's actions, despite their comrades' attempts to stop them)
* [[Franchise/SonicTheHedgehog Rouge the Bat]] vs. [[WesternAnimation/PAWPatrol Ladybird]] (female thieves with flight and superhuman strength)
* [[VideoGame/FireEmblemTheBindingBlade Roy]] vs. VideoGame/{{Elsword}} (Teenage, red-haired swordsmen with pyrokinesis)
* [[Toys/{{Jewelpet}} Ruby]] vs...
** [[Manga/MyHeroAcademia Katsuki Bakugo]] (anime characters with explosive powers, though Ruby's are unintentional)
** WesternAnimation/{{Bunnicula}} (extremely powerful red-eyed rabbits loyal to female masters)
** [[VideoGame/SonicAdvanceTrilogy Cream The Rabbit]] (Superpowered rabbits)
** [[VideoGame/YokaiWatch Jibanyan]] ({{Mon}} franchise mascots)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Trixie Lulamoon]] vs...
** [[Franchise/HarryPotter Draco Malfoy]] (Two arrogant magic users/magicians who consider themselves higher than others and are the rivals of the protagonist)
** [[Toys/{{Jewelpet}} Luea]] (Both of them have similarly arrogant personalities, magic powers, and rivals that match their species [Twilight and Ruby respectively])
** [[WesternAnimation/StevenUniverse Peridot]] (redeemed antagonists with similar personalities)
* [[WebAnimation/{{RWBY}} Ruby Rose]] vs...
** [[WebAnimation/{{TOME}} Alpha]] (Main protagonists of Web Animations with superhuman abilities and a red motif)
** [[VideoGame/{{Darkstalkers}} BB Hood]] ({{Little Red Fighting Hood}}s)
** [[VideoGame/NoMoreHeroes2DesperateStruggle Margaret Moonlight]] (gun-scythe wielding {{Action Girl}}s)
** [[Franchise/KingdomHearts Marluxia]] (flower-motif scythe wielders)
** [[Franchise/BlackRockShooter Dead Master]] (black dress-clad scythe users)
** [[Manga/SoulEater Maka Albarn]] (heroic, scythe-wielding {{Action Girl}}s)
* [[VideoGame/{{Paladins}} Ruckus]] vs. [[VideoGame/BattleBorn Toby]] (Little guys in [[MiniMecha Mini Mechas]] who love destruction)
* [[Franchise/StreetFighter Rufus]] vs. [[VideoGame/{{Tekken}} Bob]] (Big fat guys who a capable of moving [[{{Acrofatic}} crazy fast]] despite the massive size and hate the idea of becoming slim)
* [[Franchise/{{Persona}} Ryuji Sakamoto]] vs. [[Manga/SailorMoon Sailor Jupiter]] (Electromancers who fight monsters with a fighting squad and gain new forms in their journeys. Both are often mistaken for delinquents due to their appearances and are generally the muscle of the group)
* [[Franchise/FateSeries Saber]] vs. [[Franchise/KingdomHearts Aqua]] (Female swordfighters who are the chosen wielders of powerful, significant blades, were once part of a group of warriors, were once corrupted by dark forces after seeing their allies be consumed by darkness before being purified by the protagonist and allies connected to them)
* [[Manga/OnePiece Sabo]] vs. [[Manga/MagiLabyrinthOfMagic Alibaba Saluja]] (Blonde-haired, pyrokinetics who despite their royal status became revolutionaries)
* [[ComicBook/SabrinaTheTeenageWitch Sabrina Spellman]] vs. [[Franchise/HarryPotter Hermione Granger]] (Iconic fictional witches)
* [[Manga/SailorMoon Sailor Moon]] vs...
** [[Manga/SaintSeiya Pegasus Seiya]] (Strong powerhouses from retro anime that are embodiments of the cosmos, team leaders, along with love interests who they protect)
** [[Franchise/TouhouProject Reimu Hakurei]] (Powerful female mages who exist in universes where most powerful entities (be they their allies or foes) are female, to which both fight against powerful entities to protect mankind)
** [[Manga/CardCaptorSakura Sakura Kinomoto]] (The two most famous magical girls, who have had a rivalry since the 90s)
* [[Franchise/StreetFighter Sakura Kasugano]] vs...
** [[Manga/RanmaOneHalf Akane Tendo]] (Japanese schoolgirl martial artists)
** [[Franchise/{{Tekken}} Asuka Kazama]] (Kind-hearted, female martial artists from Japan who have two rivals, one being the main protagonist of each work [Ryu for Sakura, Jin for Asuka]] and the other being a noblewoman in a dress [Karin for Sakura, Lili for Asuka])
** [[Franchise/DragonBall Videl Satan]] (Energetic, female proteges who aspire to become expert martial artists)
* [[Manga/{{Naruto}} Sakura Haruno]] vs...
** [[Manga/TheSevenDeadlySins Diane]] ({{Action Girl}}s from {{Shonen}} manga, who rely on their SuperStrength in combat)
** [[Toys/{{Jewelpet}} Garnet]] (The short-tempered, pink-haired girls of main trios from anime)
** [[Manga/MagiLabyrinthOfMagic Morgiana]] (Pink-haired female anime characters with super strength that become love interests to the deuteragonists)
* [[Manga/CardcaptorSakura Sakura Kinomoto]] vs. [[Franchise/LyricalNanoha Nanoha Takamachi]] (two very iconic anime {{Magical Girl}}s)
* [[Franchise/SpiderMan Sandman]] vs...
** [[Franchise/{{Batman}} Clayface]] (Supervillains made of sand and clay respectively that can physically alter their bodies, and eventually underwent a HeelFaceTurn)
** [[Manga/OnePiece Crocodile]] (Villains with the power to control and turn into sand and have a weakness to water)
* [[VideoGame/{{Undertale}} Sans]] vs...
** [[VideoGame/EarthBound Ness]] (Partially a meme-based fight, but with honest connections of the two being from mascots of beloved RPG series [to which the latter's inspired the former] who are pacifists with magical abilities to allow them to fight against an all-powerful evil entity, with the latter being a loner while the former fights with their friends)
** [[VideoGame/PokemonRubyAndSapphire Shedinja]] (Undead OneHitPointWonder monsters from [=RPGs=] that are surprisingly hard to kill)
** [[VideoGame/{{OFF}} The Judge]] (Recurring side characters from popular indie [=RPGs=] who are {{PerpetualSmiler}}s, guide a protagonist who is an avatar [Frisk for Sans, the Batter for the Judge] have brothers who die [or at least can die, in Sans' case], and fight the protagonist when they try to destroy everything)
* [[Manga/{{Naruto}} Sasori]] vs. [[VideoGame/BlazBlue Relius Clover]] ({{Marionette Master}}s who're {{Evil Puppeteer}}s, to boot)
* [[Manga/JujutsuKaisen Satoru Gojo]] vs...
** [[Manga/JoJosBizarreAdventure Gyro Zeppeli]] (Eccentric, playful and at times bizarre-acting mentors to the main protagonist. In their youth, both were introduced to an ability passed down through their noble families which allowed them to distort and manipulate space by imprinting the very fabric of it with a limitless convergence of a concept, with both being referred to as wielding "the power of infinity". As a result of this mastery, both have general good nature can give way to a proud, almost arrogant persona, with both being notable for their sharp tongue and general lack of respect for both friends and enemies. They also become known as the two most adept users of this ability thanks to the utilization of a specialized eye(s) that significantly augments their mastery of this ability and allows them to utilize their abilities to a greater extent as well as operate with additional supernatural ocular abilities that greatly enhance the natural usefulness of their line of sight)
** [[Manga/BungoStrayDogs Osamu Dazai]] (Mentors to the protagonists who usually act silly to the point of annoying others, but can get serious when the time calls for it. Both have an ability that is considered extremely powerful in the context of their story, as well as a serious, blond-haired coworker they tend to annoy, and a past connection to the BigBad)
** [[Manga/ChainsawMan Makima]] (Leaders of demon-killing organizations and mentors to the protagonists [Yuji Itadori for the former, Denji for the latter] of popular Magazine/ShonenJump series from the 2010s who received animated versions from Creator/{{MAPPA}}, with the former being a protagonist while the latter becoming a personal and major antagonist)
* [[Anime/KillLaKill Satsuki Kiryuin]] vs...
** [[Anime/PantyAndStockingWithGarterbelt Stocking Anarchy]] ({{Master Swordswom|an}}en who wield katanas, wear white transformation outfits, have long, dark hair, are the sister of their respective series' protagonist, betrayed their "allies", and were made [at least in part] by the [[Creator/StudioGainax same]] [[Creator/StudioTrigger people]])
** [[WesternAnimation/TheLegendOfKorra Kuvira]] (Female dictators with super powers)
** [[VideoGame/FireEmblemThreeHouses Edelgard von Hresvelg]] (Female members of a royal family that were experimented on at an early age, join a prestigious academy that they later wage war against, lead small groups, seem tyrannical but in truth want humanity to live free of the influence of a powerful, female being, and have rivals who re their siblings, with Satsuki having a blue and white color scheme and believing in power while Edelgard has a red and black color scheme and believes in justice)
* [[Franchise/TolkiensLegendarium Sauron]] vs...
** [[VideoGame/TheElderScrollsIIIMorrowind Dagoth Ur]] (Seemingly unkillable, semi-divine evil overlords seeking to corrupt the world, commanding armies of misshapen creatures and dark sorcerers, ruling from a {{Mordor}} on top of a high mountain or volcano, and having their lives bound to an item or artifact that must be destroyed to kill them)
** [[Toys/{{Bionicle}} Makuta Teridax]] (Dark Lords that want a specific McGuffin to take over)
** The [[VideoGame/{{Warcraft}} Lich King]] (Powerful, armored commanders of undead armies from works in a fantasy setting who were defeated in the past but came back in the present of their worlds to be major antagonists)
* [[Franchise/StarWars Savage Opress]] vs. [[Manga/ElfenLied Mariko]] (The second most powerful being in an alien race who are only surpassed by their siblings and wield invisible weapons)
* [[VideoGame/TeamFortress2 Saxton Hale]] VS...
** [[Franchise/MortalKombat Kano]] (Muscular {{Awesome Aussie}}s who run an organization that engages in less-than legal activities, and who fight anyone who gets in their way)
** [[VideoGame/MetalGearRisingRevengeance Senator Armstrong]] (Muscular {{Blood Knight}}s with SuperStrength and {{Badass Baritone}}s)
** [[LightNovel/{{Durarara}} Shizuo Heiwajima]] (Badasses with CharlesAtlasSuperpower. The former is a BloodKnight while the latter is a ReluctantWarrior unless [[HairTriggerTemper provoked]])
* [[Manga/FullmetalAlchemist Scar]] vs. [[Manga/HunterXHunter Kurapika]] (Scarlet-eyed agents of vengeance as they called themselves and are the best among their people until they were slaughtered by another faction)
* [[Franchise/SpiderMan Scarlet Spider (Kaine Parker)]] vs...
** [[LightNovel/ShakuganNoShana Shana]] ([[AntiHero Anti-Heroic]] {{Tsundere}}s associated with the color red, who develop over time into more conventionally heroic characters)
** [[Franchise/TheKingOfFighters K']] (Edgy, anti-heroic successors to main protagonists that became protagonists after having their genes manipulated)
* [[Series/ChouSeiKantaiSazerX Sazer Mithras]] vs. [[VideoGame/MortalKombat Kitana]] (female CombatHandFan users)
* Franchise/ScoobyDoo vs. [[WesternAnimation/CourageTheCowardlyDog Courage]] (Cowardly dogs who fight against monsters from cartoons, to which they serve as mascots from)
* ComicBook/ScottPilgrim vs. VideoGame/ViewtifulJoe ({{Idiot Hero}}es driven by the love for their girlfriends. Scott can weaponize video games while Joe can weaponize filming techniques)
* [[VideoGame/MetalGearRisingRevengeance Senator Armstrong]] vs...
** [[Manga/JoJosBizarreAdventure Funny Valentine]] (well-intentioned, superpowered patriots who seek to guide the United States to a new age of prosperity)
** [[Toys/{{Jewelpet}} Dian]] (These two [[BigBad Big Bads]] fight to purge the weak so the strong can survive and make their respective worlds great again. Both have played ball-related sports [football and basketball respectively]. Both own giant fire-belching rides weaker than themselves. Both are fistfighters with superhuman strength. Both turn black with red eyes. Both are so tough that only specific weapons [Jetstream Sam's sword and combined Jewelpet magic fired out of Rinko's Jewel Stick respectively] can do any lasting damage to them. Both can light their fists on fire to create fiery eruptions and throw fireballs respectively. And to top it all off, both were defeated by a hero with white hair and glowing red eyes [Raiden and Ruby respectively])
** [[Franchise/StreetFighter G]] (Idealistic, influential politicians who embody their beliefs and have secret agendas that, when completed, would supposedly help the people of their world, with Armstrong seeking to strengthen their country through war while G seeks for world peace)
* [[Manga/SgtFrog Sergeant Keroro]] vs...
** [[VideoGame/MeltyBlood Neco-Arc]] (4th-wall-breaking joke characters who act as mascots for their respective series)
** [[WesternAnimation/InvaderZim Zim]] (Comically incompetent alien invaders)
* [[Manga/InuYasha Sesshomaru]] vs. [[Manga/{{Bleach}} Byakuya Kuchiki]] (extremely powerful [[AloofBigBrother Aloof Big Brothers]] and {{Bishounen}})
* [[Franchise/YuGiOh Seto Kaiba]] vs. [[Series/KamenRiderExAid Kamen Rider Gemn]] (InsufferableGenius head of a gaming corporation)
* VideoGame/{{Shantae}} vs...
** [[VideoGame/FreedomPlanet Sash Lilac]] (Purple haired Half-Breeds who can attack using their hair)
** [[WesternAnimation/KimPossible Shego]] (Female Experts of Magic and Combat with a Hero vs. Villain Dynamic)
** [[VideoGame/GravityRush Kat]] (Cute superpowered teenagers who are the local heroes of their hometowns.)
** [[VideoGame/{{ARMS}} Twintelle]] ({{Action Girl}}s who fight with their hair)
** [[Franchise/TheLegendOfZelda Midna]] (Female god-like figures who attack using their hair)
* [[Franchise/MortalKombat Sheeva]] vs. [[WesternAnimation/Ben10 Looma Red Wind]] (Female, high-ranking commanders of a war-hungry race of four-armed monsters)
* [[Manga/{{Vagabond}} Shinmen Takezo]] vs. [[ComicBook/UsagiYojimbo Miyamoto Usagi]] (fictional versions of the same [[UsefulNotes/MiyamotoMusashi legendary swordsman]])
* [[VideoGame/SystemShock SHODAN]] vs. [[WesternAnimation/CodeLyoko XANA]] (Evil computer viruses)
* Franchise/{{Shrek}} vs...
** [[WesternAnimation/MonstersInc Sulley]] (Iconic heroic CGI movie monsters who both debuted in 2001 and originally start off by scaring others to maintain their lifestyles, but later have a change of heart.)
** [[WesternAnimation/IceAge Manny]] (CGI film-series protagonists who starts off as grumpy loners before reluctantly befriend an annoying animal whom they rescued and escort someone with the animal's help which causes them to open up and even start a family)
* [[VideoGame/XenobladeChronicles1 Shulk]] vs...
** [[Manga/JoJosBizarreAdventureGoldenWind Diavolo]] (A battle of [[CombatClairvoyance future sight]]. One can [[ScrewDestiny change fate]] while the other believes [[YouCannotFightFate fate is inescapable]])
** [[VideoGame/FireEmblemThreeHouses Byleth]] (Heroes of Creator/{{Nintendo}}-owned [=JRPGs=] who wield legendary swords, were born with the purpose of hosting an ancient {{God}} within their bodies, are undead, and have time-related powers)
** [[VideoGame/LegacyOfKain Raziel]] (Undead swordsmen who wield [[LivingWeapon living swords]], have [[AliensOfLondon English accents]], are connected to a malevolent and ancient entity, whose main motivation in their game is to seek out {{Revenge}}, and who eventually decide to ScrewDestiny)
** [[WesternAnimation/SheRaAndThePrincessesOfPower She-Ra (Netflix)]] (Protagonists who are chosen wielders of legendary weapons only they can wield at full potential that grant them great power [[spoiler:who also find out that they are [[ItSucksToBeTheChosenOne meant to be weapons of destruction]] before eventually having to use replicas of their weapons]])
* [[ComicBook/DoctorStrange Shuma-Gorath]] vs. [[ComicBook/JusticeLeagueOfAmerica Starro]] (Marvel vs. DC fight of powerful entities with similar physical traits (having one eye and tentacles) who seek to rule over everyone)
* [[WesternAnimation/IceAge Sid]] vs. [[Franchise/StarWars Jar Jar]] (bumbling {{Plucky Comic Relief}}s who were casted out then joins the protagonists who saved their lives)
* [[Franchise/SonicTheHedgehog Silver the Hedgehog]] vs...
** [[Franchise/DragonBall Trunks]] (Spiky-haired heroes who traveled to the past to kill an entity responsible for the BadFuture they come from and have super forms)
** [[VideoGame/CrashBandicoot Tawna Bandicoot]] (Animalistic heroes who traveled from a BadFuture to aid the protagonist in fighting a threat they originally failed to defeat)
* [[ComicBook/GreenLantern Sinestro]] vs...
** [[Franchise/BlazBlue Yuuki Terumi]] (Former heroes who betrayed their allies for their own benefit, lead evil organizations, get more powerful the more people fear them, and become beast-like entities in their most powerful state [Parallax for Sinestro, Susanoo for Terumi)
** [[Literature/{{It}} Pennywise]] (Powerful beings that both embody fear and get stronger the more people fear them)
* [[VideoGame/DarkSouls Sif]] vs. [[Franchise/{{Pokemon}} Zacian]] (Giant dogs who fight with swords that they [[CutlassBetweenTheTeeth hold in their mouths]])
* [[Franchise/{{Castlevania}} Simon Belmont]] vs...
** [[VideoGame/BloodstainedRitualOfTheNight Miriam]] ([[WhipItGood Whip-wielding]] demon slayers of 2D action games who are affected by a curse that slowly kills them. Also a case of original vs SpiritualSuccessor.)
** [[VideoGame/GhostsNGoblins Sir Arthur]] (protagonists of NintendoHard horror-themed action platformer franchises)
* [[WesternAnimation/HeManAndTheMastersOfTheUniverse Skeletor]] vs. [[WesternAnimation/ThunderCats Mumm-Ra]] (undead-themed villains whose respective archenemies (He-Man and Lion-O) have already fought each other in Death Battle)
* [[Franchise/TheLegendOfZelda Skull Kid]] vs. [[Franchise/SonicTheHedgehog Infinite]] (Mask-wearing antagonists from Japanese video games that were once unassuming members of their species until gaining an artifact that can warp reality [Majora for Skull Kid, the Phantom Ruby for Infinite])
* [[{{Manga/Berserk}} Skull Knight]] vs. the [[Franchise/FateSeries First Hassan]] (Powerful, imposing knights who are coated in armor [including a skull-like helmet], existed for centuries, are not afraid to kill, are gruff with a kind heart, save the protagonist from dark deities, and are referred to with royal aliases)
* [[WesternAnimation/PAWPatrol Skye]] vs. [[WesternAnimation/PJMasks Owlette]] (Pink-clad high flyers from two popular preschool shows that actually have plenty of stuff that would be useful in combat. Both of them also have wind attacks, and the original female members of their respective teams)
* [[VideoGame/TeamFortress2 The Sniper]] vs...
** [[Franchise/LupinIII Daisuke Jigen]] (Calm gunslingers who keep their heads and hats down while acting as snipers for their teams)
** [[VideoGame/{{Overwatch}} Ana Amari]] (Snipers from rival team-based shooters)
** [[VideoGame/{{Overwatch}} Hanzo Shimada]] (Same as above, but with the added difference of that the former uses a more modern rifle while the latter uses a traditional bow)
** [[VideoGame/BattleBorn Marquis]] (snipers from hero shooters, with the former being an honorable figure who is mistaken as a common criminal while the latter is a sadistic serial killer with the appearance of a gentleman)
* [[VideoGame/MetalGear Solidus Snake]] vs. [[Manga/FullmetalAlchemist Führer King Bradley]] (One-eyed leaders of military groups who seek to defend their country and wield swords)
* [[WesternAnimation/AvatarTheLastAirbender Sokka]] vs. [[Manga/OnePiece Usopp]] (Both are funny and sharp-witted characters who grew up in a village where they lead children to be warriors and started out as comic-relief only to become competent warriors in their own way despite lacking the standard abilities of their respective series)
* [[VideoGame/{{Overwatch}} Soldier: 76]] vs...
** [[VideoGame/TeamFortress2 The Soldier]] (Rocket-launching soldiers who also have "soldier" in their alias from rivalling team-based soldiers, with the former having regrets about his past while the latter embraces it)
** [[WesternAnimation/TheIncredibles Mr. Incredible]] (Once popular heroes who became outcasts and biligantes after the downfall of heroic organizations and the populace growing to dislike them, with the former attacking criminals and resenting the world and his past while the latter saved lives in secret and longing to become loved by the masses again)
* [[VideoGame/{{Overwatch}} Sombra]] vs...
** [[VideoGame/{{Paladins}} Skye (Paladins)]] (purple-clad {{Stealth Expert}}s who utilize a cloaking device)
** [[VideoGame/WatchDogs Aiden Pearce]] (Master hackers from modern video games)
** [[VideoGame/WatchDogs Marcus Holloway]] (Same as above, but also including the connection of them working with a team of anti-heroes)
** [[VideoGame/WatchDogs Wrench]] (Same as above)
* [[Franchise/{{Godzilla}} SpaceGodzilla]] vs. [[Franchise/UltraSeries Ultraman Belial]] (Dark reflections of classic kaiju-fighting heroes who were corrupted by extraterrestrial meddling)
* ComicBook/SpiderManNoir vs. [[ComicBook/{{Flashpoint}} Flashpoint Thomas Wayne]] (DarkerAndEdgier AlternateUniverse AntiHero versions of Spider-Man and Batman respectively)
* [[Anime/CowboyBebop Spike Spiegel]] vs...
** [[Manga/BlackLagoon Revy]] (Anime mercenaries who are toughened anti-heroes who are often regarded to be among the greatest gun-slingers in anime history, mostly traveling around on a ship sharing the same name of their series. Both are part of a 4-person crew of other outlaws where they have the designated niche as the main marksmen; said crew composes of a big burly guy, a techie, and a new recruit whom they initially didn't get along with but then they eventually become a sort of love interest. Additionally, both have nicknames based on their fighting styles ("Swimming Bird" and "Two-Hands") and are often seen smoking a cigarette throughout their series in a set-up that is basically a "slice-of-life but with guns" premise, fighting against mob crews, teaming up with other bounty hunters, and completing life-risking odd job missions)
** Anime/SpaceDandy (SpaceWestern protagonists made by Creator/StudioBones)
** [[WesternAnimation/TheVentureBrothers Brock Samson]] (OneManArmy companions)
* [[VideoGame/KillerInstinct Spinal]] vs...
** [[VideoGame/SoulSeries Cervantes de Leon]] (Undead pirates from fighting games, with the former being a hero and the latter a villain)
** [[VideoGame/BattleMonsters Fangore]] (fighting game skeletons with swords)
** [[VideoGame/MediEvil Sir Daniel Fortesque]] (skeletal swordsmen)
* [[Franchise/TeenageMutantNinjaTurtles Splinter]] vs. [[WesternAnimation/KungFuPanda Shifu]] (rodent {{Old Master}}s and expert martial artists)
* WesternAnimation/SpongeBobSquarePants vs. [[VideoGame/TheLegendaryStarfy Starfy]] (Protagonists of children's media who are sea animals, are more powerful than they appear, and commonly aid others in need, with the former being a standard, working-class adult while the latter is a child belonging to royalty)
* [[Series/LazyTown Sportacus]] vs...
** [[VideoGame/BarkleyShutUpAndJamGaiden Charles Barkley]] (sports-themed superheroes [the latter retains his superpowered AdaptationalBadass status])
** [[WesternAnimation/PAWPatrol Chase]] (blue superhero speedsters who save lives, use tennis balls as weapons, have young boys and girls to help them, are heavily associated with a pink girl, mainly protect a town, and oppose a goofy villain dressed in purple)
* [[VideoGame/FiveNightsAtFreddys Springtrap]] vs...
** [[Franchise/{{Danganronpa}} Junko Enoshima]] (Murderous, mysterious masterminds who corrupted a seemingly innocent place to serve as the launchpad for their schemes, use a mascot to mask their identity, returned from the dead in a cybernetic form, and are the {{Greater Scope Villain}}s of their series)
** [[Film/ChildsPlay Chucky]] (Serial killers who are trapped in a non-human body of a normally innocent object [William Afton/Springtrap being in the body of an animatronic while Charles Lee Ray/Chucky is in the body of a doll])
* [[VideoGame/TeamFortress2 The Spy]] vs...
** [[VideoGame/AmongUs The Imposter]] (stealthy killers)
** [[VideoGame/{{Dota2}} Riki]] (Valve characters who're invisible backstabbers)
** [[VideoGame/{{Hitman}} Agent 47]] (Expert assassins who use stealth to their advantage)
** [[VideoGame/{{Overwatch}} Sombra]] (Stealth-based fighters from rival team-based shooters who specialize in sabotaging the enemy team)
* [[VideoGame/FinalFantasyVIII Squall Leonhart]] vs...
** [[WebAnimation/{{RWBY}} Ruby Rose]] (Protagonists who train at an academy for warriors and wield blade-gun hybrid weapons)
** [[WebAnimation/{{RWBY}} Qrow Branwen]] (Gun blade wielding swordsmen who seem to be born unluckly on a quest to save the world from an evil witch)
** [[Franchise/{{Persona}} Tatsuya Suou]] ([[TheStoic Stoic]], sword-wielding protagonists with a [[AnimalMotifs lion motif]], who are later discovered [[spoiler:to have had a childhood friendship with their party members that they've all forgot due to a traumatic event]])
** [[Anime/ShamanKing Yoh Asakura]] (Warriors who use spirits to enhance themselves)
** [[Videogame/Persona4 Yu Narukami]] (Leaders of a group of teens who fight with summons)
* [[VideoGame/KirbyPlanetRobobot Star Dream]] vs. [[VideoGame/{{Bayonetta}} Jubileus]] ([[RealityWarper Reality-warping]] [[FinalBoss final bosses]] planning to wipe out all life in the universe)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Starlight Glimmer]] vs. [[WesternAnimation/TheLegendOfKorra Amon]] (Villains who despise individuality and take it away. Though Starlight is reformed and moved on, Amon embodies her biggest inner demon)
* [[WesternAnimation/{{Archer}} Sterling Archer]] vs...
** Film/AustinPowers ({{Deconstructive Parod|y}}ies of Film/JamesBond)
** [[WesternAnimation/AmericanDad Stan Smith]] (Anti heroes with ties to secret agencies)
* [[VideoGame/{{Minecraft}} Steve]] VS...
** [[VideoGame/{{Pikmin}} Captain Olimar]] (explorers of open-world games)
** [[VideoGame/LittleBigPlanet Sackboy]] (world creators)
** [[VideoGame/{{Terraria}} The Terrarian]] ([[TheStoic Emotionless]] [[PlayerCharacter player characters]] who explore and fight against a world trying to kill them by gathering materials and making weapons and houses)
** [[WesternAnimation/TheLEGOMovie Emmet]] (Blocky protagonists who can create anything)
* [[Anime/DarlingInTheFranxx Strelizia]] vs. [[Anime/NeonGenesisEvangelion EVA-02]] (Bio-engineered mechas by teenage girls with traumatic experiences and are associated with the number 2)
* [[Series/SpiderManJapan Supaidaman]] vs...
** Anime/BatmanNinja (Japanese versions of Spider-Man and Batman respectively)
** [[Series/Batman1966 Sixties Batman]] (Less serious and more goofy versions of Spider-Man and Batman respectively)
* [[ComicBook/TheAvengers Super-Adaptoid]] vs. [[ComicBook/JusticeLeagueOfAmerica Amazo]](Marvel vs. DC fight of robots who fight against and copy the powers of an entire team of superheroes)
* [[ComicBook/AmalgamUniverse Super Soldier]] vs. [[ComicBook/InfinityWars2018 Soldier Supreme]] (alternate versions of Captain America amalgamated with different superheroes)
* ComicBook/SwampThing vs. ComicBook/ManThing (Marvel vs. DC battle of powerful swamp monsters made of greenery and can control plants with "-Thing" in their names)
[[VideoGame/{{Warcraft}} Sylvanas Windrunner]] vs. [[VideoGame/StarCraft Sarah Kerrigan]] (Female protagonists turned antagonists from video game series owned by Creator/BlizzardEntertainment, being once noble warriors who were corrupted by dark forces to become a major antagonist in their series)
[[Franchise/{{Terminator}} T-1000]] vs. [[Film/TheThing1982 The Thing]] (Morphing, mutating monsters from movies who disguise themselves as people)
* [[WesternAnimation/KungFuPanda Tai Lung]] vs...
** [[WesternAnimation/{{Ninjago}} Morro]] (Former students of the BigGood who were raised under the belief that they were TheChosenOne, only to get rejected for the role, leading to them performing a FaceHeelTurn that results in their imprisonment, which they escape from during the events of the story)
** [[WesternAnimation/AvatarTheLastAirbender Ty Lee]] (kung fu villains who use PressurePoint attacks)
* [[VideoGame/SoulSeries Taki]] vs...
** [[VideoGame/DeadOrAlive Kasumi]] ({{Fanservice}}y kunoichi considered iconic their respective fighting game series)
** [[VideoGame/SenranKagura Asuka]] (Female ninjas who are protagonists and [[Fanservice are known for being sexual]])
* [[VideoGame/SoulSeries Talim]] vs...
** [[VideoGame/{{Tekken}} Josie Rizal]] (Filipino characters from Creator/BandaiNamcoEntertainment games)
** [[VideoGame/SamuraiShodown Nakoruru]] (Protectors of Nature)
** [[Franchise/{{Persona}} Yosuke Hanamura]] (teenagers who [[DualWielding dual wield]] bladed weapons, use wind-based magic that they can use for both [[BlowYouAway attack]] and [[HealingWinds support]], and who [[FragileSpeedster make up for their poor defense by being extremely fast]])
* [[LightNovel/SagaOfTanyaTheEvil Tanya von Degurechaff]] vs...
** [[VideoGame/GranblueFantasy Cagliostro]] (Brilliant, [[CuteAndPsycho shocking vicious]] magicians who are men trapped in the bodies of little girls of small stature with blond hair)
** [[Manga/OnePiece Akainu]] (Cruel, magical enforcers of dictatorial organizations, with the former being unassuming but truly wicked while the latter plays his appearance straight)
** [[Manga/{{Hellsing}} Alexander Anderson]] (Same as above)
** [[Anime/IzettaTheLastWitch Izetta]] (Militaristic magical girls fighting in world wars, with the former being a villainous protagonist who fights for German forces while the latter is a hero who fights against them)
** [[Manga/{{Hellsing}} Seras Victoria]] (Female enforcers of organizations who use both magic and traditional machinery, with the former being a vicious and villainous figure who serves a dictatorial organization while the latter is a hero who fights against one)
* [[WebAnimation/MetaRunner Tari]] vs. [[WesternAnimation/GlitchTechs Miko Kubota]] ([[GamerChick Gamer Chicks]] that have AmbiguouslyHuman origins and wear an advanced technological armwear attached to them that allows them to access and scan various video game data and have interacted with various video game characters and their worlds and has even befriended a video game character that has come to life in the real world. Both are also taken in by their corporations/companies for their unique and odd abilities and have to deal with the number one hot-headed gaming champion rival who are also on the same team as them. Both also have wielded a hammer at one point)
* [[Franchise/MarvelUniverse Taskmaster]] vs. [[Manga/ShuumatsuNoWalkureRecordOfRagnarok Kojiro Sasaki]] (master swordsmen who've fought with some of the greatest warriors in their worlds, copying their moves and using them to their fullest advantage)
* [[Manga/AkameGaKill Tatsumi]] vs. [[Franchise/FateSeries Sieg]] (Young knights who can summon incredibly durable armor derived from a dragon that they obtained from the sacrifice of another hero, can turn invisible, have powerful dragon-related weapons, and can transform into more draconic forms the more power they use with the caveat of them possibly turning into dragons with using them)
* [[VideoGame/{{Warcraft}} Thrall]] vs. [[TabletopGame/Warhammer40000 Ghazghkull]] (Fantasy vs. Sci-Fi fight of orcs who lead an army of their race)
* [[Manga/{{Bleach}} Tier Harribel]] vs. [[LightNovel/HighSchoolDxD Xenovia Quarta]] (Calm and cool yet {{Fanservice}}y swordswomen who lead organizations and fight against evil entities, with Tier being a supernatural entity while Xenovia hunts them)
* [[WesternAnimation/TheFairlyOddParents Timmy Turner]] vs. [[ComicStrip/CalvinAndHobbes Calvin]] (Children who team up with invisible imaginary friends whose greatest weapon is their imagination)
* [[Franchise/{{Persona}} Tohru Adachi]] vs. [[Manga/JoJosBizarreAdventure Yoshikage Kira]] (serial killers from the fourth entries of their respective series aided by familiar-like beings)
* [[Manga/MyHeroAcademia Tomura Shigaraki]] vs...
** [[Manga/{{Naruto}} Kabuto Yakushi]] (Teenage villains with tragic backstories before becoming mentees of a feared villain who learn to step out of their mentor's shadow and gain the ability to use other people's special abilities)
** [[WebAnimation/{{RWBY}} Cinder Fall]] (Antagonists who became resentful of heroism due to feeling neglected by them and desire to change the status quo to fit their desires by following the command of another villain)
** [[Manga/{{Naruto}} Obito Uchiha]] (The proteges of a villain from a manga/anime series from Magazine/ShonenJump who were once heroes but turned away from it after feeling wronged, now desiring to change society to their desires)
* [[Film/Scarface1983 Tony Montana]] vs. [[Series/TheWire Omar Little]] (one of fiction's most famous drug dealers against a man famous for robbing them)
* [[LightNovel/ACertainMagicalIndex Touma Kamijou]] vs...
** [[Manga/{{Bleach}} Moe Shishigawara]] (Powerful punchers, Touma having bad luck while Moe has good luck)
** [[Manga/MyHeroAcademia Izuku Midoriya]] (Regular teenage boys granted extraordinary superpowers)
** [[LightNovel/HighSchoolDxD Issei Hyoudou]] (People with dragons inside them, with Touma has an UnwantedHarem while Issei is a HaremSeeker)
** [[Franchise/FateSeries Shirou Emiya]] (CluelessChickMagnet amnesiacs with chronic hero syndrome and unique powers)
** [[Manga/BlackClover Asta]] (young heroes with a strong sense of justice who can cancel magical powers)
* [[Toys/{{Jewelpet}} Tour]] vs. [[Franchise/{{Shrek}} Puss in Boots]] (Green-eyed Spanish cat thieves whose greatest weapons are their eyes: Tour [[MagicalEye casts spells with his]] while Puss mesmerizes others with his PuppyDogEyes. Both cats are also romantically linked to Ruby and Kitty Softpaws respectively.)
* [[VideoGame/NoMoreHeroes Travis Touchdown]] vs...
** [[VideoGame/MadWorld Jack Cayman]] (protagonists of ultra-violent UsefulNotes/{{Wii}}-exclusive games)
** ComicBook/ScottPilgrim (nerd fighters that can turn enemies into coins)
** [[ComicBook/GuardiansOfTheGalaxy Star-Lord]] (Anti-heroic bounty-hunters with a cocky personality, fight their own family members, are often associated with a certain type of media, and go to space to fight aliens)
** [[Manga/MyHeroAcademia Overhaul]] (assassins of the superhuman variety)
* [[VideoGame/{{Tyrian}} Trent Hawkins]] vs. [[VideoGame/RaptorCallOfTheShadows The Raptor Mercenary]] (pilots of [[MadeOfIron surprisingly durable]] ShootEmUp craft)
* [[Anime/{{Symphogear}} Tsubasa Kazanari]] vs. [[Franchise/{{Persona}} Yukari Takeba]] (Teenage celebrities who lead a double life fighting monsters that can only be killed by people with special abilities, works on a team alongside other ability users, becomes emotionally distant after the death of a loved one, and initially resents another team member who inherited the loved ones power, but eventually gets over it and becomes friends with them)
* [[Manga/Reborn2004 Tsunayoshi Sawada]] vs. [[Manga/{{Beelzebub}} Oga Tatsumi]] (high school students roped into business that's way over their heads)
* [[Manga/MyHeroAcademia Tsuyu Asui]] vs. [[ComicBook/XMen Toad]] (Mutants with amphibian abilities)
* [[WebAnimation/{{RWBY}} Tyrian Callows]] vs. [[WebAnimation/MadnessCombat Tricky]] (lunatic killers from web series renowned for their fast-paced, fluid battle scenes)
* [[VideoGame/DeadRising Tyrone King]] vs...
** The [[VideoGame/MadWorld Black Baron]] (Antagonists who are large orchestrators of televised events that put a spotlight on general bloodbaths)
** [[WebAnimation/{{RWBY}} Roman Torchwick]] (Wealthy, power-hungry manipulators who seek to cheat their way into becoming powerful)
* [[Manga/{{Bleach}} Ulquiorra Cifer]] vs. [[Franchise/KingdomHearts Xemnas]] (Humanoid beings of darkness and emptiness who serve evil organizations and seek to become human, acquiring it in death)
* [[Franchise/UltraSeries Ultraman]] vs...
** Series/ZoneFighter (Similar-looking superheroes with a wide array of technological abilities who grow to massive sizes to fight kaiju and save the planet)
** [[Franchise/{{Godzilla}} Jet Jaguar]] (Same situation as above, although using a more iconic character)
* [[VideoGame/{{Undertale}} Undyne]] vs...
** The [[WebComic/OnePunchMan Deep Sea King]] (Fishwoman who's a parody of [[ShonenDemographic Shonen]] heroes vs. Fishman who's a parody of Shonen villains)
** [[Franchise/KingdomHearts Xaldin]] (Fighting with multiple lances)
** [[VideoGame/MegaMan9 Splash Woman]] (aquatic {{Action Girl}}s who fight with similar weapons)
** [[Franchise/{{Kirby}} Bandana Waddle Dee]] (Spear users who both serve a king)
** [[WesternAnimation/StevenUniverse Pearl]] (Spear-wielders who serve as major protagonists in a group)
* WesternAnimation/UncleGrandpa vs. [[WesternAnimation/CoconutFredsFruitSaladIsland Coconut Fred]] (Childlike entities from cartoons with reality warping powers)
* [[Manga/JoJosBizarreAdventure Vanilla Ice]] vs. [[Manga/{{Baoh}} Walken]] (Characters created by Creator/HirohikoAraki who are long-haired, deranged minions who can erase matter)
* [[Franchise/StreetFighter Vega]] vs. [[VideoGame/SoulSeries Voldo]] (Villainous fighting game characters who are minions, are from European countries [Vega being French while Voldo is Italian] attack using bladed weapons, and are seeking for something [Vega seeking beauty while Voldo seeks the Soul Edge], with Vega dating those he deems ugly while Voldo has a very unsightly appearance)
* [[WesternAnimation/Ben10 Vilgax]] vs. [[Franchise/{{Superman}} General Zod]] (Former alien generals who betrayed their race following their banishment to an extradimensional prison for disobedience who became intergalactic warlords who attempted to conquer Earth)
* [[ComicBook/{{Spawn}} Violator]] vs...
** [[Literature/{{It}} Pennywise]] (Sadistic and cruel monsters who take the form of {{Monster Clown}}s)
** [[WebAnimation/MadnessCombat Tricky]] (Same as above)
* [[Franchise/PowerRangers Venjix/Evox]] vs...
** [[WesternAnimation/CodeLyoko XANA]] (Evil computer viruses)
** [[VideoGame/SystemShock SHODAN]] (Same as above)
* [[VideoGame/TalesOfBerseria Velvet Crowe]] VS...
** [[VideoGame/Drakengard3 Zero]] ({{Action Girl}}s with demonic powers whose goals are to kill someone personal to them.)
** [[VideoGame/FinalFantasyXV Noctis Lucis Caelum]] (Protagonists from the latest entries of their franchises who're motivated by revenge.)
** [[Franchise/{{Persona}} Akira Kusuru/Ren Amamiya/Joker]] (Protagonists from the latest entries of their franchises who have criminal records that were wrongly convicted and are against those that are [[VillainWithGoodPublicity Villains that look good to the public]])
** [[VideoGame/DevilMayCry Nero]] (People with demonic murder-arms who oppose the local CorruptChurch)
* [[WesternAnimation/HotWheelsBattleForce5 Vert Wheeler]] vs. [[WesternAnimation/{{Motorcity}} Mike Chilton]] (leaders of a FiveManBand that have weaponized cars)
* [[VideoGame/DragaliaLost Volk]] vs. [[Franchise/TouhouProject Seija Kijin]] (Two antagonistic individuals whose goals involve having the weak dominate the strong.)
* [[Series/BreakingBad Walter White]] vs. [[Franchise/{{Saw}} John Kramer]] (Old men with crappy life who become infamous not-so-well-intentioned criminals with an iconic alias after being diagnosed with cancer, rather weak physically but are genius and have engineering skills)
* [[Manga/JoJosBizarreAdventure Wamuu]] vs. [[Franchise/StreetFighter Necalli]] (Ancient warriors who seek to fight strong opponents, with one being an honorable fighter while the other is a vicious, honorless monster)
* [[Manga/OnePiece Whitebeard]] vs...
** [[Manga/TheSevenDeadlySins Escanor]] (Huge, muscular, charismatic, mustached men full of pride, who are both feared, as well as respected throughout the world for their might and pride, and also serve as support for the protagonist, [[spoiler:even after their unfortunate passing]])
** [[Manga/{{Bleach}} Genryusai Yamamoto]] (extremely powerful old men who serve as leaders)
** [[Manga/HunterXHunter Isaac Netero]] (same reason as above)
* [[Literature/TheChroniclesOfNarnia White Witch]] vs. [[Literature/TheWonderfulWizardOfOz Wicked Witch of the West]] (evil witches)
* ComicBook/{{Wiccan}} vs. [[Podcast/TheAdventureZone Taako]] (powerful gay wizards)
* [[WesternAnimation/LooneyTunes Wile E. Coyote]] vs. [[Franchise/TomAndJerry Thomas "Tom" Cat]] (Animalistic, mute, and villainous protagonists from Creator/WarnerBros who try and fail time-and-time again to defeat their rivals using technology)
* [[VideoGame/{{Overwatch}} Winston]] vs. [[ComicBook/TheFlash Gorilla Grodd]] (hyper-intelligent gorillas)
* [[Franchise/StarFox Wolf]] vs...
** [[Franchise/MortalKombat Kano]] (Ruthless, one-eyed mercenaries and leaders of criminal groups that are constantly pursued by government-employed agents who are their rivals. Both also once teamed up with their enemies to take out a bigger threat than them)
** [[Franchise/KungFuPanda Tai Lung]] (Grey-colored rivals to the main protagonist who serve as dark reflections of them, with the former using futuristic weaponry while the latter uses martial arts and seeks magical power)
* WesternAnimation/WordGirl vs. [[WesternAnimation/MiraculousLadybug Ladybug]] (Teenage female superheroes who have a large cast of villains and have secret identities that they must keep from their friends.)
* [[Series/StarTrekTheNextGeneration Worf]] vs. [[Franchise/MassEffect Urdnot Wrex]] (space opera {{proud warrior race guy}}s)
* ComicBook/{{X 23}} vs...
** [[WesternAnimation/DannyPhantom Dani Phantom]] (younger {{Opposite Sex Clone}}s who are more than capable of being able to fight on par with their originals)
** [[Franchise/MortalKombat Mileena]] (Clones who have a major physical difference from the original that differentiates them, and are extremely violent in combat)
* The [[Franchise/{{Alien}} Xenomorph]] vs. the [[Series/StrangerThings Demogorgon]] (Monstrous, eyeless creatures with strange months who are subservient to a larger monster, with the former being a biological creature while the latter is supernatural)
* [[Manga/{{Bleach}} Yhwach]] vs...
** [[Manga/{{Naruto}} Kaguya Ōtsutsuki]] (Powerful antagonists from manga/anime series who existed for millennia and return in their series present to enact their evil schemes)
** [[Franchise/KingdomHearts Master Xehanort]] (Major antagonists who cause a large amount of events in their series, lead an army of shadows, and fight against a hero who fights against said shadows)
** [[VideoGame/XenobladeChronicles1 Zanza]] (Fate-changing, god-like beings who serve as the final antagonist of their works, were driven to insanity by a desire of power, and seek to destroy humanity)
** [[VideoGame/StarWarsTheOldRepublic Darth Vitiate]] (Leaders of dark empires who return after years of absence to attack the world, gain power through consuming the lifeforce of others, were originally powerless but gained power through their deeds [including killing their fahers] to the point they are now referred as god-like beings, constantly return from the dead, and gained enough power to become nearly-unstoppable concepts of destruction before meeting their ends at the hands of [[spoiler:their children]])
* [[Anime/{{GurrenLagann}} Yoko Littner]] vs. [[VideoGame/GodEater Alisa Ilinichina Amiella]] (Female marksmen who fight against invading monsters)
* [[Manga/{{Bleach}} Yoruichi Shihouin]] vs...
** [[Creator/DCComics Black Lightning]] (Electromancers who grew up as very talented individuals who exceeded in almost every category and became teachers to a group of teens who needed their guidance. Both are also not fully recognized as heroes as they are more akin to vigilantes associated with heroic groups and still do the right thing)
** [[Manga/{{Naruto}} Minato Namikaze]] (Insanely fast ex-leaders that were mentors to other powerful characters in the series and also reveal hidden power in the last arc of their series)
** [[Manga/YuYuHakusho Younger Toguro]] vs. [[Manga/{{Berserk}} Nosferatu Zodd]] (Muscular, powerful rivals to heroes from classic manga/anime who seek to fight strong opponents and are honorable despite their status as villains)
* [[Franchise/YuGiOh Yugi Muto]] vs...
** [[Anime/PokemonTheSeries Ash Ketchum]] (Monster summoners from early 2000s anime (that were dubbed by 4Kids) that summon monsters to fight other monsters in 1v1 battles, with both series eventually spawning popular card games based on them)
** [[Manga/CardCaptorSakura Sakura Kinomoto]] (Monster summoners who summon monsters with cards to fight against other monsters)
** [[Literature/TheKaneChronicles Carter Kane]] (Teens involved in ancient Egyptian magic and realms)
* [[Manga/BlackClover Yuno]] vs...
** [[Manga/FairyTail Wendy]] (Orphan children skilled in [[BlowYouAway Wind Magic]] that had a backstory they weren't fully aware of)
** [[WesternAnimation/TheLegendOfKorra Zaheer]] (Clever and innovative Masters of {{Blow You Away}} that go against their country's status quo)
** [[Manga/JoJosBizarreAdventure Wamuu]] (Skilled fighters that use {{Blow You Away}} and show respect toward the main character more than most and {{Undying Loyalty}} towards their leaders despite evidence against it [Vangeance letting Patry wreak hell on the kingdom, Kars having no real sense of honor])
** [[LightNovel/ReZero Emilia]] ({{Chaste Hero}} Spirit users subject to {{All of the Other Reindeer}} which hinders their desires to rule over their country. They are very close with {{The Hero}} but aren't afraid to call them out on their flaws. They also use their magic for {{Spontaneous Weapon Creation}} albeit vastly preferring [[HeroesPreferSwords swords]]. Finally, they have elven ancestry [Emilia being a half-elf, Yuno having the soul of a half-elf inside him since birth] and are picked up by villains who themselves were to {{All of the Other Reindeer}} for their own goals [Patry, and by extension Vangeance to revive all the elves, Roswaal to revive Echidna)
* [[Manga/FutureDiary Yuno Gasai]] vs....
** [[VideoGame/YandereSimulator Ayano Aishi]] ({{Yandere}} vs. {{Yandere}})
** [[VisualNovel/HigurashiWhenTheyCry Rena Ryuugu]] ({{Yandere}} vs. CuteAndPsycho)
** [[LightNovel/ShakuganNoShana Shana]] ({{Tsundere}}s vs. {{Yandere}}s)
** ComicBook/HarleyQuinn (another case of {{Yandere}} vs. {{Yandere}})
* [[VideoGame/TalesOfVesperia Yuri Lowell]] vs...
** [[VideoGame/FireEmblemPathOfRadiance Ike]] (Swordfighters who lead their own band of mercenaries from fantasy [=RPGs=])
** [[ComicBook/XMen Psylocke]] (Heroic swordfighters with long, purple hair)
** [[VideoGame/GenshinImpact Diluc]] (Former knights who left an organization and later fought against it following them noticing their corruption, including that of sweeping the deaths of their masters under the rug)
* [[Franchise/{{Persona}} Yusuke Kitagawa]] vs. [[VideoGame/DragonQuest Sylvando]] (Eccentric RPG party members who are the fifth members of their team, have issues with their fathers, and dedicate their lives to the arts [Yusuke for painting, Sylvando for performing])
* [[Manga/YuYuHakusho Yusuke Urameshi]] vs...
** [[Manga/HunterXHunter Gon Freecss]] (Protagonists of manga created by Creator/YoshihiroTogashi and published by Magazine/ShonenJump)
** Manga/InuYasha (demonic heroes from retro anime who fight against evil spiritual entities)
** Series/KamenRiderGhost (teenagers who gained ghost superpowers after dying)
** [[Franchise/TouhouProject Reimu Hakurei]] (Humans [or at least originally human] with strong magical powers who fight against evil spiritual beings in realms made for them)
* [[Franchise/BlazBlue Yuuki Terumi]] vs. [[LightNovel/DateALive Isaac Westcott]] (Extremely powerful antagonists who delivered a countless amount of crimes ForTheEvulz)
* [[Franchise/DragonBall Zamasu]] vs...
** [[Franchise/FateSeries Goetia]] (God-like entities who once watched over humanity before they came evil after growing discontent with them [with Zamasu being disgusted by humanity and seeking to destroy it while Goetia desires to "save" it from its flaws], seek to destroy the universe to recreate it to their liking, stole the bodies of mortals, have multiple forms [including one they obtain after [[FusionDance fusing with an alternate version themselves]] to defeat the heroes], wear important rings, and use powerful wish-granting tools in their quest for domination)
** [[Manga/SaintSeiya Hades]] (Powerful deities who seek to destroy humanity)
** [[Franchise/{{Digimon}} Lucemon]] (Powerful, evil deities who [[FallenHero were once good]] but now seek to destroy the world to remake it in their image)
* [[Franchise/{{Pokemon}} Zekrom]] vs. [[Franchise/YuGiOh Red-Eyes Black Dragon]] (Legendary black dragon OlympusMons who can [[FusionDance fuse together]] with other, similar dragons to become even more powerful)
* [[Series/PowerRangersZeo Zeo Megazord/Super Zeo Megazord]] vs. [[Anime/{{Voltron}} Vehicle Voltron]] (The 2nd Power Ranger team vs the 2nd/Other Voltron Force as a sequel)
* [[VideoGame/GodOfWar Zeus]] vs. [[VideoGame/AsurasWrath Deus]] (Prideful, electrokinetic deities who lead a group of deities, fight against a god-slayer who seeks revenge on the gods for killing their families)
* [[WesternAnimation/InvaderZim Zim]] vs...
** [[VideoGame/DestroyAllHumans Crypto]] (Mini alien invaders that want to TakeOverTheWorld and uses many various gadgets to do so)
** [[WebAnimation/HelluvaBoss Moxxie]] (Two small inhuman invaders that are voiced by Creator/RichardStevenHorvitz)
** [[Animation/BoBoiBoy Adu Du]] (Green aliens with funny robot sidekick; they are looked down back on their home planet and go to Earth in order to gain fellow aliens' respect; their primary foe is a young boy)
* [[VideoGame/GuiltyGear Nagoriyuki]] vs...
** [[VideoGame/{{Castlevania}} Alucard]] (Vampiric swordsmen with heavy ties to the antagonists of their franchises [Happy Chaos for Nagoriyuki, Dracula for Alucard])
** [[VideoGame/BlazBlue Hakumen]] (Extremely powerful swordsmen dressed in white outfits and eyeless masks from [[Creator/ArcSystemWorks ArcSys]] fighting games)
* [[Manga/OnePiece Nami]] vs. [[VideoGame/FinalFantasyVII Yuffie]] (Kind-hearted and noble thieves that were originally antagonistic towards a small group of heroes, but eventually joining with said group in order to go on many adventures)
* [[Film/TheLastSamurai Nathan Algren]] vs. [[VideoGame/{{Nioh}} William Adams]] (Western Samurai.)
* [[ComicBook/TheBlackKnight Nathan Garrett]] vs. [[VideoGame/FireEmblemRadiantDawn General Zelgius]] (villains with enchanted swords and the label of {{black knight}})
* [[VideoGame/MeltyBlood Neco-Arc]] vs. [[VideoGame/{{Undertale}} Temmie]] (Strange yet comedic creatures with cat-like traits who break the fourth wall)
* [[WesternAnimation/DarkwingDuck Negaduck]] vs. [[WesternAnimation/KungFuPanda2 Lord Shen]] (Evil avian rivals)
* [[Manga/NegimaMagisterNegiMagi Negi Springfield]] vs. [[Anime/LittleWitchAcademia Akko Kagari]] (Anime mages inspired by Literature/HarryPotter)
* VideoGame/Nier vs. [[VideoGame/ShadowOfTheColossus Wander]] (Warriors from depressing fantasy games who wander across ruined landscapes, fight against monsters of darkness, and unlock seals to aid a magical figure in hope of them helping them save those they care for, with Nier's aid [Weiss] being played straight while Wander's aid [Dormin] [[spoiler:manipulated him into doing his bidding and is responsible for his demise]])
* The [[Franchise/ResidentEvil Nemesis T-Type]] vs...
** [[Franchise/SilentHill Pyramid Head]] (Humanoid, brutish monsters with large weapons from two of the most beloved horror video game series of all time, with Nemesis wielding ranged weapons and mutating throughout its appearances while Pyramid Head wields a melee weapon and stays largely the same)
** The [[VideoGame/BioShock Big Daddy]] (Large, scary monsters who don't speak much, were created through genetic tampering, and designed for a specific goal with opposite relations to a certain group [The Big Daddies being created to protect the Little Sisters while the Nemesis T-Type was created to hunt down and kill members of S.T.A.R.S.])
* [[Toys/{{Jewelpet}} Nephrite]] vs. [[VideoGame/MetalGearSolid Sniper Wolf]] (canine-themed snipers)
* [[VideoGame/{{Neptunia}} Neptune/Purple Heart]] vs...
** Series/KamenRiderExAid (Clumsy and absentminded caretakers with two personalities whose love of retro gaming is exceptionally relevant, as their job is keeping the peace in a world filled with threats related to that very subject)
** [[Franchise/{{Persona}} Yu Narukami]] (Sword-wielding JRPG protagonists who draw power from their connection of others, and lead a team of heroes with similar powers to them)
* [[Manga/JoJosBizarreAdventure Narancia Ghirga]] vs. [[WebAnimation/{{RWBY}} Coco Adel]] (Flamboyant members of a group who both have abilities that allow them to fire projectiles and scan areas for enemies)
* [[Franchise/{{Pokemon}} Necrozma]] vs. [[Webcomic/MobPsycho100 Toichiro Suzuki]] ([[PowerParasite Power-stealing]] antagonists who seek to throw their worlds into chaos)
* [[VideoGame/DevilMayCry Nero]] vs...
** [[Manga/DGrayMan Allen Walker]] (Silver-haired demon hunters who have cursed arms)
** ComicBook/{{Hellboy}} (Snarky, revolver-wielding anti-heroes who possess both a RedRightHand and a demonic heritage)
** [[VideoGame/FinalFantasyXV Noctis Lucis Caelum]] (Anti-heroic heroes who wield swords longside magic and fight against their evil fathers)
** [[VideoGame/FinalFantasyVII Vincent Valentine]] (anti-heroic, BadassLongcoat-clad revolver users who wield demonic power)
* [[ComicBook/{{SHIELD}} Nick Fury]] vs...
** ComicBook/JudgeDredd ([[CoolOldGuy Elderly]], {{lawful neutral}} operatives of not-so-nice government institutions who outwit and overpower enhanced individuals with guile, experience, and basic weaponry)
** [[Franchise/{{Batman}} Commissioner Gordon]] (Marvel vs. DC fight of leaders of human forces who aid heroes)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Nightmare Moon]] Vs. [[VideoGame/PrimalRage Vertigo]] (moon-dwelling maniacs)
* [[VideoGame/NightsIntoDreams NiGHTS]] vs. WesternAnimation/PeterPan (Flying, playful figures who take children to mysterious realms to fight off against evil forces)
* [[VideoGame/FinalFantasyXV Noctis Lucis Caelum]] vs...
** [[VideoGame/NierAutomata 2B]] (Stoic protagonists who wear black and are expert weapon masters)
** [[VideoGame/FireEmblemAwakening Chrom]] (Sword-wielding royalty who lead a group of four people on grand adventures)
* [[VideoGame/HeavyRain Norman Jayden]] vs. [[VideoGame/DeadlyPremonition Francis York Morgan]] (FBI agents from video games)
* [[VideoGame/PowerBlade NOVA]] vs. [[VideoGame/SkeletonBoomerang Hunter]] (Platform game protagonists who fight with boomerangs)
* [[Anime/KillLaKill Nui Harime]] vs...
** [[Manga/FistOfTheNorthStar Jagi]] (Evil adoptive siblings that serve as personal rivals to the protagonists [Jagi for impersonating Kenshiro and manipulating Shin, Nui for killing Ryuko's father] who are scarred by the protagonist in some form [with Jagi having his faceplate and helm to cover the disfiguring wound Kenshiro gave him while Nui having her prosthetic arms following Ryoko cutting them off])
** [[VideoGame/{{Darkstalkers}} Baby Bonnie Hood]] (Young girls who look sweet and innocent, but are actually [[TheFakeCutie two of the most psychotic and dangerous characters of their respective series]])
* [[Literature/CthulhuMythos Nyarlathotep]] vs. [[Literature/TheDarkTower Walter Padick/Randall Flagg]] (Immortals whose actions have cemented them as the overall BigBad of their respective franchises, have taken many [[IHaveManyNames names]] and faces over the course of history, commit terrible actions against humanity [[ForTheEvulz simply of the sake of it]], and who are really just a minion to their franchise's GreaterScopeVillain)
* [[ComicBook/{{Asterix}} Obelix]] vs...
** [[ComicBook/{{Suske en Wiske}} Jerome]] (The strongest characters in both worlds, who also originate from different time periods)
** [[VideoGame/MetalGearRisingRevengeance Senator Armstrong]] (Same as above)
* [[WesternAnimation/StevenUniverse Obsidian]] vs. [[VideoGame/MarioAndLuigiPaperJam Shiny RoboBowser]] (giant fusion forms featured in final battles. Obsidian is used against a final boss while Shiny [=RoboBowser=] is one)
* [[Manga/MyHeroAcademia Ochako Uraraka]] vs...
** [[VideoGame/GravityRush Kat]] (Female superheroes who control gravity)
** [[Manga/JoJosBizarreAdventure Koichi Hirose]] (Young school students with power over gravity)
** [[Animation/BoBoiBoy Yaya Yah]] (Same as above, but both are pink, feminine {{NiceGirl}}s)
* [[VideoGame/AstralChain Officer Howard]] vs...
** [[VideoGame/XenobladeChronicles2 Rex]] (Protagonists from modern Creator/Nintendo video games with a blue color scheme who fight alongside a construct)
** [[VideoGame/ChaosLegion Sieg Wahrheit]] (hack-and-slash protagonists whose fighting styles rely on swords and summoned Legions)
* ComicBook/OldManLogan vs. [[ComicBook/TeenageMutantNinjaTurtlesTheLastRonin The Last Ronin]] (BadFuture versions of mutant superheroes who are the last living member of their team)
* [[ComicBook/{{Invincible}} Omni-Man]] vs...
** [[Manga/BakiTheGrappler Yujiro Hanma]] (Abusive fathers who are also the strongest beings in their respective settings)
** [[Franchise/DragonBall Bardock]] (Superhuman warriors who are the fathers of the main protagonist who were originally villainous figures who worked for their tyrannical race before they betrayed them)
* [[Manga/{{Naruto}} Orochimaru]] vs. [[Manga/SoulEater Medusa Gorgon]] (Snake-themed villains from manga/anime who have major connections to a protagonist)
* [[Manga/MyHeroAcademia Overhaul]] vs...
** [[Manga/OnePiece Trafalgar Law]] (Crime lords from Magazine/ShonenJump manga/anime who can disassemble and reassemble objects, with the former being a vicious, cruel figure who never redeemed himself while the latter eventually became a hero)
** [[Franchise/ResidentEvil Albert Wesker]] (Cruel antagonists who lead evil organizations, can kill with just a touch, preform experiments on others, mutated throughout their appearances, and desire power, with the latter being loving towards his boss while the latter killed his boss to get ahead in his schemes)
* [[Franchise/{{Pokemon}} Palkia]] vs. [[Franchise/DragonBall Omega Shenron]] (Two dragon-like lifeforms who were created as higher beings as part of a group, made to do certain jobs. However, they usually go after their "comrades", and were eventually put down via what is the opposite of their powers)
* [[Franchise/{{Pokemon}} Palossand]] vs. [[VideoGame/MegaManBattleNetwork3WhiteAndBlue DesertMan.EXE]] (living sand creatures consisting of a head and two arm-like appendages)
* [[VideoGame/KidIcarusUprising Palutena]] vs...
** [[Franchise/SuperMarioBros Rosalina]] (Goddesses from Nintendo video game series who rule over a realm in a non-earthly realm [Rosalina ruling over the Comet Observatory in space with Palutena ruling Skyworld] who protect a race of divine beings [The Lumas for Rosalina, the angels for Palutena])
** [[WesternAnimation/MyLittlePonyFriendshipIsMagic Princess Celestia]] ([[GodOfGood Heroic goddesses]] who can [[LightIsGood control light]] and [[TheGadfly enjoy messing with their subjects, but still mean well]])
** [[Franchise/TheLegendOfZelda Midna]] (Goddesses from Creator/Nintendo games who live in realms reflecting their opposite abilities, with Palutena [who has heavenly abilities] living in a realm of light while Midna [who has abilities based on shadows] living in a realm of darkness)
* [[Manga/JoJosBizarreAdventure Pannacotta Fugo]] vs...
** [[WesternAnimation/MiraculousLadybug Chat Noir]] (blonde pretty boys with the power of untold destruction)
** [[Manga/AkameGaKill Akame]] (Assassins who wield powerful toxins that can easily kill their targets, started out as promising children before their downfall who unlocked special abilities after accepting their faults)
* [[WesternAnimation/SpongeBobSquarePants Patrick Star]] vs...
** [[WesternAnimation/TheAmazingWorldOfGumball Richard Watterson]] (pink FunnyAnimal, FatIdiot, lazy and unemployed ManChild from cartoons)
** [[WesternAnimation/EdEddNEddy Ed]] (Generally friendly and unintelligent cartoon characters with impressive strength)
* [[WebAnimation/{{RWBY}} Penny Polendina]] vs. [[Series/PowerRangersOperationOverdrive Mack Hartford]] (Young-kind heroes from a popular series, but not a well-liked series [[spoiler:who turn out to be an android made by their father [[HumanityEnsues and became human later on]]]] and has ties with relics.
* Franchise/PercyJackson vs. [[WesternAnimation/StevenUniverse Lapis Lazuli]] (Water manipulators)
* [[WesternAnimation/MickeyMouse Pete]] vs. [[ComicStrip/{{Popeye}} Bluto]] (Brutish rivals of animated protagonists who seek their lover's affection but is always defeated by their rivals)
* ComicStrip/ThePhantom vs. Radio/TheShadow (sneaky, mysterious, often gunslinging pulp proto-superheroes)
* [[VideoGame/{{Overwatch}} Pharah]] vs...
** [[VideoGame/{{Paladins}} Drogoz]] (FlyingFirepower characters from [[HeroShooter Hero Shooters]] who use jetpacks and rocket launchers to rain down death from above)
** [[VideoGame/TeamFortress2 The Soldier]] (Soldiers who utilize rockets to attack their foes from rivalling team-based shooters)
* [[WesternAnimation/{{Chaotic}} Phelphor]] vs. [[Franchise/CthulhuMythos Cthulhu]] (monsters with MindControl powers who originate from the sea)
* [[Franchise/MarvelCinematicUniverse Phil Coulson]] vs. [[Franchise/{{Batman}} Commissioner Gordon]] (Marvel vs. DC fight of leaders of human forces who aid heroes)
* [[VideoGame/{{Paladins}} Pip]] vs. [[VideoGame/{{Gigantic}} Uncle Sven]] (HeroShooter support characters who fight using potions and alchemy)
* [[VideoGame/AtelierSophieTheAlchemistOfTheMysteriousBook Plachta]] vs. [[Franchise/{{Persona}} Sophia/Sophie]] (Beings resembling young girls who have a mysterious past and take residence inside an object owned by the game's protagonist)
* [[VideoGame/ShovelKnight Plague Knight]] vs...
** [[VideoGame/LeagueOfLegends Ziggs]] (Short but formidable foes who utilize explosives in many different ways using science.)
** [[VideoGame/{{Skylanders}} Pop Fizz]] (Crazy short potion using foe who use their potions in different and creative ways)
* [[VideoGame/GuiltyGear Potemkin]] vs. [[VideoGame/BlazBlue Iron Tager]] (Large grapplers with mechanical gauntlets who serve as soldiers from [[Creator/ArcSystemWorks ArcSys]] fighting games)
* [[WesternAnimation/TheRenAndStimpyShow Powdered Toast Man]] vs. [[WesternAnimation/RockosModernLife Really Really Big Man]] (parody superheroes)
* The Franchise/{{Predator}} VS...
** The [[Franchise/{{Alien}} Xenomorph]] (Dangerous aliens from horror movies who [[Franchise/AlienVsPredator crossed paths multiple times before))
** [[VideoGame/StarCraft Zeratul]] (honor-bound alien warriors who can turn invisible)
** [[Franchise/StarWars The Mandalorian]] (Space-travelling bounty hunters who wear masks and armor, use high-tech weaponry, and follow a code of honor)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Princess Luna]] vs...
** [[WesternAnimation/RiseOfTheGuardians Pitch Black]] (wielders of darkness who can enter peoples' dreams)
** [[VideoGame/MegaManX8 Dark Mantis]] (another wielder of darkness. Luna may be able to use his weapon too.)
** [[Franchise/{{Kirby}} Dark Matter]] (a [[RuleOfThree third]] darkness-based being)
* [[VideoGame/Dota2 Pudge]] vs. [[VideoGame/{{Overwatch}} Roadhog]] ({{Fat Bastard}}s who use a hook on a chain as a weapon)
* ComicBook/ThePunisher vs...
** ComicBook/JudgeDredd (JudgeJuryAndExecutioner)
** [[VideoGame/{{Overwatch}} Soldier: 76]] (former military heroes turned violent vigilante men after life-changing tragedy)
* [[VideoGame/XenobladeChronicles2 Pyra]] vs. [[Franchise/FateSeries Nero]] (Female swordfighters dressed in red who are bound to the soul of their master, with their masters also fighting in wars and seeking things that are magical [Rex seeking Elysium while Hakuno seeks the Holy Grail)
* [[VideoGame/TeamFortress2 The Pyro]] vs...
** [[Franchise/{{Batman}} Firefly]] (flamethrower-wielding pyromaniacs)
** [[VideoGame/{{Overwatch}} Mei]] (Fire vs. ice matchup of characters with similar roles from rival team-based shooters, with the former being a crazed maniac who has the mind of a child while the latter is a caring, brilliant scientist)
** [[VideoGame/{{Overwatch}} Roadhog]] (Masked criminals that take no issue with causing carnage, with the former using mainly ranged weapons while the latter uses melee attacks)
* [[WebAnimation/{{RWBY}} Pyrrha Nikos]] vs...
** [[ComicBook/TheMightyThor Lady Sif]] (formidable swordswomen who're among the greatest warriors in their respective realms)
** [[Manga/JoJosBizarreAdventure Noriaki Kakyoin]] (Red-headed members of a team that they are considered the brains of, which both having lonely pasts and were [[spoiler:eventually killed by major antagonists]])
* [[WebAnimation/{{RWBY}} Qrow Branwen]] vs...
** [[Manga/MyHeroAcademia Shota Aizawa]] (Badass teachers, that both look like homeless people)
** [[Manga/SoulEater Spirit Albarn]] (presumably wielded by either Stein or Lord Death) (Familial figures to teenage female scythe-wielding protagonists, who also use scythes, or in Spirits' case ''is'' the scythe)
* [[Franchise/MortalKombat Quan Chi]] vs...
** [[VideoGame/{{Darkstalkers}} Jedah Dohma]] ({{Big Bad}}s attempting to summon a GodOfEvil)
** ComicBook/{{Taskmaster}} (villainous characters who can copy the fighting styles of others)
* [[WesternAnimation/DuckDodgers Queen Tyr'ahnee]] vs. [[WesternAnimation/MyLifeAsATeenageRobot Queen Vexus]] (evil "queens")
* [[VideoGame/BlazBlue Rachel Alucard]] vs. [[Franchise/ShinMegamiTensei Alice]] (Powerful, unholy entities with the appearance of young girls in fancy clothes.)
* [[Anime/KillLaKill Ragyo Kiryuin]] vs...
** [[Manga/SoulEater Medusa Gorgon]] (MagnificentBastard villainesses infamous for being [[AbusiveParents abusive mothers]])
** [[VideoGame/PokemonSunAndMoon Lusamine]] (BigBad [[ArchnemesisMom mothers]] who are AxCrazy, borderline obsessed with alien lifeforms from another dimension [the Life Fibres and the Ultra Beasts respectively], wear variants of said lifeforms to become even more powerful, and are opposed by both the main protagonists and their own daughters)
* [[WesternAnimation/XiaolinShowdown Raimundo Pedrosa]] vs. [[WesternAnimation/{{Ninjago}} Lloyd Garmadon]] (Chosen heroes from teams of Eastern-themed elemental warriors who become the leaders of their teams despite first turning evil.)
* [[Franchise/MortalKombat Rain]] vs...
** [[VideoGame/FireEmblemFates Corrin]] (People who were born of nobility but became separated from them soon after birth, wield water as their primary means of attack, were the main player in a civil war, and both have an unusual heritage which puts them above others [Corrin being half-dragon and Rain being a demigod])
** [[Manga/JoJosBizarreAdventure Weather Report]] (Children of powerful families who were separated from them at birth with arrogant demeanors [by default with Rain, as [[spoiler:Wes Bluemarine]] with Weather Report], [[spoiler:seek to avenge loved ones who were killed at the hands of major antagonists of their series [Shao Khan and Argus for the former, Enrico Pucci for the latter]]], have the ability to control water and electricity, are named after musicians [Music/Prince for the former, Music/WeatherReport for the latter])
** [[Franchise/{{Pokemon}} Greninja]] (Hydrokinetic ninjas)
* [[Franchise/StreetFighter Rainbow Mika]] vs. [[Franchise/TheKingOfFighters Ángel]] (Sensual female wrestlers from fighting games whose stories involve corrupt organizations who host tournaments)
* [[Literature/{{Dragonlance}} Raistlin Majere]] vs. [[Literature/TheElricSaga Elric of Melniboné]] (Sickly albino sorcerers)
* [[WesternAnimation/RandyCunninghamNinthGradeNinja Randy Cunningham]] vs...
** [[Series/PowerRangersSamurai Jayden Shiba]] (teenage high-school heroes clad in red and black suits based on Japanese warriors [Ninja and Samurai respectively] who inherited their suits from another and protect their hometowns from the forces of evil)
** [[WesternAnimation/MiraculousLadybug Ladybug]] (teenaged high school heroes that wear black and red tight suits and set out to save innocent people who have been corrupted by dark magic from the BigBad)
* [[Manga/FistOfTheNorthStar Raoh]] vs...
** [[WebComic/OnePunchMan Garou]] (Former pupils of great masters who became powerful, anti-villainous martial artists who serve as the antithesis to their protagonists, seek to band their worlds together under a common cause [Raoh to unite the people of the world under his command to restore order, Garou to unite the world's heroes to fight against him] and to become even more powerful than they already are, have an honorable side, betrayed their masters, and can copy others' techniques)
** [[Manga/YuYuHakusho Younger Toguro]] (Muscular, powerful rivals to heroes from classic manga/anime who seek to fight strong opponents and are honorable despite their status as villains)
** [[Manga/{{Berserk}} Nosferatu Zodd]] (Same as above)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Rarity]] vs...
** [[VideoGame/MegaManX2 Crystal Snail]] ([[GemstoneAssault crystal users]])
** [[Toys/{{Jewelpet}} Garnet]] (This fashionista cat has a similar personality to Rarity. They are part of their respective shows' main groups, and both of them have also been corrupted with dark magic at certain points.)
** [[VideoGame/ThemsFightinHerds Velvet]] ([[GemstoneAssault gem magic]] vs. [[AnIcePerson ice magic]]; plus Velvet originated as an expy of Rarity)
* ComicBook/RasAlGhul vs...
** [[ComicBook/CaptainAmerica Baron Zemo]] (Marvel vs. DC fight of terrorists and assassins who lead organizations dedicated to these causes who stand in opposition to major protagonists)
** The [[ComicBook/IronMan Mandarin]] (same as above, but with both villains also having an Asian aesthetic and using magical techniques)
** [[WesternAnimation/AvatarTheLastAirbender Fire Lord Ozai]] (Leaders of evil, Asian-inspired organizations who use their daughters [Talia for Ra's, Azula for Ozai] as minions who utilize magic)
** [[Manga/JoJosBizarreAdventure Will Anthonio Zeppeli]] (Mentors to the protagonist who dedicate their lives studying a technique used to obtain eternal life, with the former being a villain who embraces the technique while the latter is a hero who fights against it)
** [[VideoGame/AssassinsCreedII Ezio Auditore]] (Master assassins and members of organizations who have done as such for centuries)
* [[Franchise/StreetFighter Rashid]] vs. [[Franchise/TheKingOfFighters Shun'ei]] (Capcom vs SNK matchup, the "new generation" heroes with a fondness for technology who use elemental powers and have an old mentor.)
* [[Franchise/{{Metroid}} Raven Beak]] vs...
** [[ComicBook/{{Invincible}} Thragg]] (Warlords who lead a group of a species related to the protagonist of each work)
** [[Franchise/{{Halo}} The Didact]] (Alien warlords who seek to conquer other planets, wear armor, and [[spoiler:mutate themselves to increase their strength]])
* [[Franchise/{{Pokemon}} Rayquaza]] vs. [[Franchise/FinalFantasy Bahamut]] (Draconic deities among the most powerful among their group of monsters who lend their power only to those who are worthy of it, utilize a wide variety of elemental abilities, and are often associated with meteors [Rayquaza is often tasked with destroying one in various games it's in and Bahamut was inside a meteor that it emerged from])
* [[VideoGame/{{Overwatch}} Reaper]] vs...
** [[VideoGame/{{Paladins}} Androxus]] (Dark and edgy masked gunslingers who are obsessed with death and excel in close-quarters combat)
** [[Franchise/MortalKombat Noob Saibot]] (Edgy, vengeful assassins dressed in black outfits and masks who have shadow-based magical abilities)
* ComicBook/RedSkull vs...
** [[Manga/JoJosBizarreAdventure Rudol von Stroheim]] (superpowered Nazis from comics)
** [[Franchise/{{Batman}} Black Mask]] (supervillains with a SkullForAHead)
** ComicBook/RasAlGhul (Supervillainous leaders of powerful organizations, with the former pursuing technology and a modern hegemonic view while the latter weaponized traditional assassination methods and magic to aid others in their goals)
* [[VideoGame/XenobladeChronicles2 Rex]] vs...
** [[VideoGame/TalesOfZestiria Sorey]] (Protagonists from fantasy [=RPGs=] whose liking towards ruins caused them to bond with a mysterious girl and fight alongside elemental constructs)
** [[Franchise/ShinMegamiTensei Nanashi]] (Once ordinary looters from [=RPGs=] who joined forces with a spiritual entity after originally dying to an evil, hegemonic figure [Jin for Rex, Adremelech for Nanashi] who summon other spiritual entities to attack and have green markings to show their bond)
** [[VideoGame/FinalFantasyV Bartz Klauser]] (Brown-haired, sword-wielding protagonists from [=RPGs=] who became legendary heroes [despite their original status as orphans] by defeating an originally ordinary entity who became corrupted y dark influence into becoming a god-like figure)
* [[Franchise/TouhouProject Reimu Hakurei]] vs. [[VideoGame/PuyoPuyo Arle Nadja]] (Cute yet powerful female mages who are kind to others and fight against dark entities)
* [[VideoGame/{{Overwatch}} Reinhardt]] vs...
** [[VideoGame/{{Paladins}} Fernando]] (Knights in futuristic PoweredArmor who use large, rectangular energy shields)
** [[WebAnimation/{{RWBY}} Nora Valkyrie]] (Hammer-wielding powerhouses with eccentric personalities that may or may not just be fronts to hide their past trauma)
** [[VideoGame/GranblueFantasy Vaseraga]] (Large knights with equally large weapons who used to command a unit of soldiers until they lost command over them in the same battle that they [[HandicappedBadass received a crippling injury]] [Reinhart losing an eye while Vaseraga was paralyzed from poison], to which they were recruited by an organization that gave them the augments required to allow them to keep fighting, with Reinhardt honoring the sacrifice his mentor made [having died in the battle that took Reinhardt's eye] while Vaseraga is haunted by his failure to protect his crew)
* [[Franchise/{{Pokemon}} Reshiram]] vs. [[Franchise/YuGiOh Blue-Eyes White Dragon]] (Legendary white dragon OlympusMons who can [[FusionDance fuse together]] with other, similar dragons to become even more powerful)
* [[VideoGame/MetalGear Revolver Ocelot]] vs. [[Franchise/KingdomHearts Xigbar]] ([[TheGunslinger Gunslingers]] who lose a part of their body to a swordsman during a battle, and act as TheDragon to the BigBad [[spoiler:while in truth actually being [[TheManInFrontOfTheMan the true mastermind behind everything]]]])
* [[Series/TheWalkingDead Rick Grimes]] vs. [[VideoGame/TheLastOfUs Joel Miller]] (anti-heroic, undead-battling {{Papa Wol|f}}ves from post-apocalyptic settings)
* [[WesternAnimation/RickAndMorty Rick Sanchez]] vs. WesternAnimation/MrPickles (ExtremeOmnisexual [[NominalHero Nominal Heroes]] from shows on Creator/AdultSwim, both of whom have young companions who act as [[MoralityPet Morality Pets]] and [[Memes/RickAndMorty an association]] [[TrademarkFavoriteFood with pickles]])
* [[VideoGame/JustCause Rico Rodriguez]] vs. [[VideoGame/BionicCommando Nathan "Radd" Spencer]] (grappling hook combatants)
* [[Franchise/{{Metroid}} Ridley]] vs...
** [[Franchise/{{Castlevania}} Death]] (major recurring bosses of the two TropeNamers of the {{Metroidvania}} genre. Both become final bosses in rare cases, and both killed fighters in trailers leading up to the release of ''VideoGame/SuperSmashBrosUltimate'')
** [[VideoGame/MegaManX Vile]] (Recurring antagonists in video game series starting arm cannon-wielding heroes that [[TheDragon serve the main antagonist as their right-hand instead of being final bosses]], themselves being violent, sadistic criminals with a purple color scheme)
** [[WesternAnimation/Ben10 Vilgax]] (Vicious alien warlords who [[WouldHurtAChild have no issue harming children]] or their loved ones)
* [[WesternAnimation/MuchaLucha Rikochet]] vs. [[WesternAnimation/ElTigreTheAdventuresOfMannyRivera El Tigre]] (Mexican child heroes)
* [[Manga/BlueExorcist Rin Okumura]] vs...
** [[WebAnimation/{{RWBY}} Adam Taurus]] ([[HornedHumanoid Horned]] swordsmen who are rejected by the worlds they live in due to their species)
** [[Manga/FireForce Shinra Kusakabe]] (Fire manipulators with a devil-theming)
* [[Manga/JoJosBizarreAdventure Risotto Nero]] vs. [[Franchise/MortalKombat Skarlet]] (Assassins who specialize in weaponizing their targets' blood)
* [[Franchise/RatchetAndClank Rivet]] vs. [[VideoGame/CrashBandicoot Tawna Bandicoot]] (Modern [=PlayStation=] game heroines who are the female counterparts of an animalistic hero from another dimension who fight against alternate counterparts of evil doctors)
* Myth/RobinHood vs...
** Myth/KingArthur (the classical heroes of legend)
** Myth/WilliamTell (Mythological archers known for their ludicrous [[SplittingTheArrow arrow-shooting]] [[WilliamTelling skills]])
* [[Series/LazyTown Robbie Rotten]] vs. [[WesternAnimation/PAWPatrol Mayor Humdinger]] (Two recurring comical purple-clad villains of popular kids' shows. Both of them also have blue-clad heroes opposing them)
* [[ComicBook/AllNewGhostRider Robbie Reyes]] vs...
** Series/KamenRiderGhost (Teens with dreams of a good life in the future involving a family member, until one day they are suddenly killed at random but come back with due to an outside force reviving them giving them super spiritual powers, and in this new form they are equipped with a blade, black jacket, and go by a title with the word "ghost" in it, and are now on a mission to stop anybody who preys on the weak)
** [[VideoGame/Splatterhouse Rick Taylor]] (Once normal humans who were revived by a manipulative supernatural entity to seek vengeance in hopes of them succumbing to their dark side, with Robbie fighting against Eli's wishes for Robbie to become a cold-blooded killer while Rick gave into the Terror Mask's demands for violence)
* [[ComicBook/GuardiansOfTheGalaxy Rocket Raccoon]] vs...
** VideoGame/SlyCooper (raccoon heroes)
** [[Franchise/LiloAndStitch Stitch]] (Genetic Experiments with expert piloting skills and precision with guns)
* [[VideoGame/FatalFury Rock Howard]] vs...
** [[Manga/JoJosBizarreAdventure Trish Una]] (Heroic children of gang leaders who are adopted by heroes and fight using melee attacks)
** [[Franchise/MortalKombat Cassie Cage]] (Children of major fighting game protagonists [albeit an adopted one, in Rock's case] who become the face of a "next-generation" cast)
* [[Literature/TheDarkTower Roland Deschain]] vs...
** [[Manga/BlackCat Train Heartnet]] (Masterful Gunslingers with a dark past and a preference for revolvers.)
** ComicBook/JonahHex (The most famous gunslinger in literature VS the most famous gunslinger in comics. Both are war veterans who have dealt with the supernatural, survived in post-apocalyptic worlds and, occasionally, gone through time travel.)
* [[Manga/JoJosBizarreAdventure Rohan Kishibe]] vs...
** [[VideoGame/{{Scribblenauts}} Maxwell]] (Users of immensely powerful, writing-centric reality-warping abilities)
** [[Franchise/{{Persona}} Yusuke Kitagawa]] (Stoic and mature yet eccentric artists who fight with the aid of {{FightingSpirit}}s)
* [[Franchise/KingdomHearts Roxas]] vs. [[VideoGame/MegaManX Axl]] (Inhuman humanoids who were once integral parts of antagonistic organizations before leaving due to the organization's actions, despite their comrades' attempts to stop them)
* [[Franchise/SonicTheHedgehog Rouge the Bat]] vs. [[WesternAnimation/PAWPatrol Ladybird]] (female thieves with flight and superhuman strength)
* [[VideoGame/FireEmblemTheBindingBlade Roy]] vs. VideoGame/{{Elsword}} (Teenage, red-haired swordsmen with pyrokinesis)
* [[Toys/{{Jewelpet}} Ruby]] vs...
** [[Manga/MyHeroAcademia Katsuki Bakugo]] (anime characters with explosive powers, though Ruby's are unintentional)
** WesternAnimation/{{Bunnicula}} (extremely powerful red-eyed rabbits loyal to female masters)
** [[VideoGame/SonicAdvanceTrilogy Cream The Rabbit]] (Superpowered rabbits)
** [[VideoGame/YokaiWatch Jibanyan]] ({{Mon}} franchise mascots)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Trixie Lulamoon]] vs...
** [[Franchise/HarryPotter Draco Malfoy]] (Two arrogant magic users/magicians who consider themselves higher than others and are the rivals of the protagonist)
** [[Toys/{{Jewelpet}} Luea]] (Both of them have similarly arrogant personalities, magic powers, and rivals that match their species [Twilight and Ruby respectively])
** [[WesternAnimation/StevenUniverse Peridot]] (redeemed antagonists with similar personalities)
* [[WebAnimation/{{RWBY}} Ruby Rose]] vs...
** [[WebAnimation/{{TOME}} Alpha]] (Main protagonists of Web Animations with superhuman abilities and a red motif)
** [[VideoGame/{{Darkstalkers}} BB Hood]] ({{Little Red Fighting Hood}}s)
** [[VideoGame/NoMoreHeroes2DesperateStruggle Margaret Moonlight]] (gun-scythe wielding {{Action Girl}}s)
** [[Franchise/KingdomHearts Marluxia]] (flower-motif scythe wielders)
** [[Franchise/BlackRockShooter Dead Master]] (black dress-clad scythe users)
** [[Manga/SoulEater Maka Albarn]] (heroic, scythe-wielding {{Action Girl}}s)
* [[VideoGame/{{Paladins}} Ruckus]] vs. [[VideoGame/BattleBorn Toby]] (Little guys in [[MiniMecha Mini Mechas]] who love destruction)
* [[Franchise/StreetFighter Rufus]] vs. [[VideoGame/{{Tekken}} Bob]] (Big fat guys who a capable of moving [[{{Acrofatic}} crazy fast]] despite the massive size and hate the idea of becoming slim)
* [[Franchise/{{Persona}} Ryuji Sakamoto]] vs. [[Manga/SailorMoon Sailor Jupiter]] (Electromancers who fight monsters with a fighting squad and gain new forms in their journeys. Both are often mistaken for delinquents due to their appearances and are generally the muscle of the group)
* [[Franchise/FateSeries Saber]] vs. [[Franchise/KingdomHearts Aqua]] (Female swordfighters who are the chosen wielders of powerful, significant blades, were once part of a group of warriors, were once corrupted by dark forces after seeing their allies be consumed by darkness before being purified by the protagonist and allies connected to them)
* [[Manga/OnePiece Sabo]] vs. [[Manga/MagiLabyrinthOfMagic Alibaba Saluja]] (Blonde-haired, pyrokinetics who despite their royal status became revolutionaries)
* [[ComicBook/SabrinaTheTeenageWitch Sabrina Spellman]] vs. [[Franchise/HarryPotter Hermione Granger]] (Iconic fictional witches)
* [[Manga/SailorMoon Sailor Moon]] vs...
** [[Manga/SaintSeiya Pegasus Seiya]] (Strong powerhouses from retro anime that are embodiments of the cosmos, team leaders, along with love interests who they protect)
** [[Franchise/TouhouProject Reimu Hakurei]] (Powerful female mages who exist in universes where most powerful entities (be they their allies or foes) are female, to which both fight against powerful entities to protect mankind)
** [[Manga/CardCaptorSakura Sakura Kinomoto]] (The two most famous magical girls, who have had a rivalry since the 90s)
* [[Franchise/StreetFighter Sakura Kasugano]] vs...
** [[Manga/RanmaOneHalf Akane Tendo]] (Japanese schoolgirl martial artists)
** [[Franchise/{{Tekken}} Asuka Kazama]] (Kind-hearted, female martial artists from Japan who have two rivals, one being the main protagonist of each work [Ryu for Sakura, Jin for Asuka]] and the other being a noblewoman in a dress [Karin for Sakura, Lili for Asuka])
** [[Franchise/DragonBall Videl Satan]] (Energetic, female proteges who aspire to become expert martial artists)
* [[Manga/{{Naruto}} Sakura Haruno]] vs...
** [[Manga/TheSevenDeadlySins Diane]] ({{Action Girl}}s from {{Shonen}} manga, who rely on their SuperStrength in combat)
** [[Toys/{{Jewelpet}} Garnet]] (The short-tempered, pink-haired girls of main trios from anime)
** [[Manga/MagiLabyrinthOfMagic Morgiana]] (Pink-haired female anime characters with super strength that become love interests to the deuteragonists)
* [[Manga/CardcaptorSakura Sakura Kinomoto]] vs. [[Franchise/LyricalNanoha Nanoha Takamachi]] (two very iconic anime {{Magical Girl}}s)
* [[Franchise/SpiderMan Sandman]] vs...
** [[Franchise/{{Batman}} Clayface]] (Supervillains made of sand and clay respectively that can physically alter their bodies, and eventually underwent a HeelFaceTurn)
** [[Manga/OnePiece Crocodile]] (Villains with the power to control and turn into sand and have a weakness to water)
* [[VideoGame/{{Undertale}} Sans]] vs...
** [[VideoGame/EarthBound Ness]] (Partially a meme-based fight, but with honest connections of the two being from mascots of beloved RPG series [to which the latter's inspired the former] who are pacifists with magical abilities to allow them to fight against an all-powerful evil entity, with the latter being a loner while the former fights with their friends)
** [[VideoGame/PokemonRubyAndSapphire Shedinja]] (Undead OneHitPointWonder monsters from [=RPGs=] that are surprisingly hard to kill)
** [[VideoGame/{{OFF}} The Judge]] (Recurring side characters from popular indie [=RPGs=] who are {{PerpetualSmiler}}s, guide a protagonist who is an avatar [Frisk for Sans, the Batter for the Judge] have brothers who die [or at least can die, in Sans' case], and fight the protagonist when they try to destroy everything)
* [[Manga/{{Naruto}} Sasori]] vs. [[VideoGame/BlazBlue Relius Clover]] ({{Marionette Master}}s who're {{Evil Puppeteer}}s, to boot)
* [[Manga/JujutsuKaisen Satoru Gojo]] vs...
** [[Manga/JoJosBizarreAdventure Gyro Zeppeli]] (Eccentric, playful and at times bizarre-acting mentors to the main protagonist. In their youth, both were introduced to an ability passed down through their noble families which allowed them to distort and manipulate space by imprinting the very fabric of it with a limitless convergence of a concept, with both being referred to as wielding "the power of infinity". As a result of this mastery, both have general good nature can give way to a proud, almost arrogant persona, with both being notable for their sharp tongue and general lack of respect for both friends and enemies. They also become known as the two most adept users of this ability thanks to the utilization of a specialized eye(s) that significantly augments their mastery of this ability and allows them to utilize their abilities to a greater extent as well as operate with additional supernatural ocular abilities that greatly enhance the natural usefulness of their line of sight)
** [[Manga/BungoStrayDogs Osamu Dazai]] (Mentors to the protagonists who usually act silly to the point of annoying others, but can get serious when the time calls for it. Both have an ability that is considered extremely powerful in the context of their story, as well as a serious, blond-haired coworker they tend to annoy, and a past connection to the BigBad)
** [[Manga/ChainsawMan Makima]] (Leaders of demon-killing organizations and mentors to the protagonists [Yuji Itadori for the former, Denji for the latter] of popular Magazine/ShonenJump series from the 2010s who received animated versions from Creator/{{MAPPA}}, with the former being a protagonist while the latter becoming a personal and major antagonist)
* [[Anime/KillLaKill Satsuki Kiryuin]] vs...
** [[Anime/PantyAndStockingWithGarterbelt Stocking Anarchy]] ({{Master Swordswom|an}}en who wield katanas, wear white transformation outfits, have long, dark hair, are the sister of their respective series' protagonist, betrayed their "allies", and were made [at least in part] by the [[Creator/StudioGainax same]] [[Creator/StudioTrigger people]])
** [[WesternAnimation/TheLegendOfKorra Kuvira]] (Female dictators with super powers)
** [[VideoGame/FireEmblemThreeHouses Edelgard von Hresvelg]] (Female members of a royal family that were experimented on at an early age, join a prestigious academy that they later wage war against, lead small groups, seem tyrannical but in truth want humanity to live free of the influence of a powerful, female being, and have rivals who re their siblings, with Satsuki having a blue and white color scheme and believing in power while Edelgard has a red and black color scheme and believes in justice)
* [[Franchise/TolkiensLegendarium Sauron]] vs...
** [[VideoGame/TheElderScrollsIIIMorrowind Dagoth Ur]] (Seemingly unkillable, semi-divine evil overlords seeking to corrupt the world, commanding armies of misshapen creatures and dark sorcerers, ruling from a {{Mordor}} on top of a high mountain or volcano, and having their lives bound to an item or artifact that must be destroyed to kill them)
** [[Toys/{{Bionicle}} Makuta Teridax]] (Dark Lords that want a specific McGuffin to take over)
** The [[VideoGame/{{Warcraft}} Lich King]] (Powerful, armored commanders of undead armies from works in a fantasy setting who were defeated in the past but came back in the present of their worlds to be major antagonists)
* [[Franchise/StarWars Savage Opress]] vs. [[Manga/ElfenLied Mariko]] (The second most powerful being in an alien race who are only surpassed by their siblings and wield invisible weapons)
* [[VideoGame/TeamFortress2 Saxton Hale]] VS...
** [[Franchise/MortalKombat Kano]] (Muscular {{Awesome Aussie}}s who run an organization that engages in less-than legal activities, and who fight anyone who gets in their way)
** [[VideoGame/MetalGearRisingRevengeance Senator Armstrong]] (Muscular {{Blood Knight}}s with SuperStrength and {{Badass Baritone}}s)
** [[LightNovel/{{Durarara}} Shizuo Heiwajima]] (Badasses with CharlesAtlasSuperpower. The former is a BloodKnight while the latter is a ReluctantWarrior unless [[HairTriggerTemper provoked]])
* [[Manga/FullmetalAlchemist Scar]] vs. [[Manga/HunterXHunter Kurapika]] (Scarlet-eyed agents of vengeance as they called themselves and are the best among their people until they were slaughtered by another faction)
* [[Franchise/SpiderMan Scarlet Spider (Kaine Parker)]] vs...
** [[LightNovel/ShakuganNoShana Shana]] ([[AntiHero Anti-Heroic]] {{Tsundere}}s associated with the color red, who develop over time into more conventionally heroic characters)
** [[Franchise/TheKingOfFighters K']] (Edgy, anti-heroic successors to main protagonists that became protagonists after having their genes manipulated)
* [[Series/ChouSeiKantaiSazerX Sazer Mithras]] vs. [[VideoGame/MortalKombat Kitana]] (female CombatHandFan users)
* Franchise/ScoobyDoo vs. [[WesternAnimation/CourageTheCowardlyDog Courage]] (Cowardly dogs who fight against monsters from cartoons, to which they serve as mascots from)
* ComicBook/ScottPilgrim vs. VideoGame/ViewtifulJoe ({{Idiot Hero}}es driven by the love for their girlfriends. Scott can weaponize video games while Joe can weaponize filming techniques)
* [[VideoGame/MetalGearRisingRevengeance Senator Armstrong]] vs...
** [[Manga/JoJosBizarreAdventure Funny Valentine]] (well-intentioned, superpowered patriots who seek to guide the United States to a new age of prosperity)
** [[Toys/{{Jewelpet}} Dian]] (These two [[BigBad Big Bads]] fight to purge the weak so the strong can survive and make their respective worlds great again. Both have played ball-related sports [football and basketball respectively]. Both own giant fire-belching rides weaker than themselves. Both are fistfighters with superhuman strength. Both turn black with red eyes. Both are so tough that only specific weapons [Jetstream Sam's sword and combined Jewelpet magic fired out of Rinko's Jewel Stick respectively] can do any lasting damage to them. Both can light their fists on fire to create fiery eruptions and throw fireballs respectively. And to top it all off, both were defeated by a hero with white hair and glowing red eyes [Raiden and Ruby respectively])
** [[Franchise/StreetFighter G]] (Idealistic, influential politicians who embody their beliefs and have secret agendas that, when completed, would supposedly help the people of their world, with Armstrong seeking to strengthen their country through war while G seeks for world peace)
* [[Manga/SgtFrog Sergeant Keroro]] vs...
** [[VideoGame/MeltyBlood Neco-Arc]] (4th-wall-breaking joke characters who act as mascots for their respective series)
** [[WesternAnimation/InvaderZim Zim]] (Comically incompetent alien invaders)
* [[Manga/InuYasha Sesshomaru]] vs. [[Manga/{{Bleach}} Byakuya Kuchiki]] (extremely powerful [[AloofBigBrother Aloof Big Brothers]] and {{Bishounen}})
* [[Franchise/YuGiOh Seto Kaiba]] vs. [[Series/KamenRiderExAid Kamen Rider Gemn]] (InsufferableGenius head of a gaming corporation)
* VideoGame/{{Shantae}} vs...
** [[VideoGame/FreedomPlanet Sash Lilac]] (Purple haired Half-Breeds who can attack using their hair)
** [[WesternAnimation/KimPossible Shego]] (Female Experts of Magic and Combat with a Hero vs. Villain Dynamic)
** [[VideoGame/GravityRush Kat]] (Cute superpowered teenagers who are the local heroes of their hometowns.)
** [[VideoGame/{{ARMS}} Twintelle]] ({{Action Girl}}s who fight with their hair)
** [[Franchise/TheLegendOfZelda Midna]] (Female god-like figures who attack using their hair)
* [[Franchise/MortalKombat Sheeva]] vs. [[WesternAnimation/Ben10 Looma Red Wind]] (Female, high-ranking commanders of a war-hungry race of four-armed monsters)
* [[Manga/{{Vagabond}} Shinmen Takezo]] vs. [[ComicBook/UsagiYojimbo Miyamoto Usagi]] (fictional versions of the same [[UsefulNotes/MiyamotoMusashi legendary swordsman]])
* [[VideoGame/SystemShock SHODAN]] vs. [[WesternAnimation/CodeLyoko XANA]] (Evil computer viruses)
* Franchise/{{Shrek}} vs...
** [[WesternAnimation/MonstersInc Sulley]] (Iconic heroic CGI movie monsters who both debuted in 2001 and originally start off by scaring others to maintain their lifestyles, but later have a change of heart.)
** [[WesternAnimation/IceAge Manny]] (CGI film-series protagonists who starts off as grumpy loners before reluctantly befriend an annoying animal whom they rescued and escort someone with the animal's help which causes them to open up and even start a family)
* [[VideoGame/XenobladeChronicles1 Shulk]] vs...
** [[Manga/JoJosBizarreAdventureGoldenWind Diavolo]] (A battle of [[CombatClairvoyance future sight]]. One can [[ScrewDestiny change fate]] while the other believes [[YouCannotFightFate fate is inescapable]])
** [[VideoGame/FireEmblemThreeHouses Byleth]] (Heroes of Creator/{{Nintendo}}-owned [=JRPGs=] who wield legendary swords, were born with the purpose of hosting an ancient {{God}} within their bodies, are undead, and have time-related powers)
** [[VideoGame/LegacyOfKain Raziel]] (Undead swordsmen who wield [[LivingWeapon living swords]], have [[AliensOfLondon English accents]], are connected to a malevolent and ancient entity, whose main motivation in their game is to seek out {{Revenge}}, and who eventually decide to ScrewDestiny)
** [[WesternAnimation/SheRaAndThePrincessesOfPower She-Ra (Netflix)]] (Protagonists who are chosen wielders of legendary weapons only they can wield at full potential that grant them great power [[spoiler:who also find out that they are [[ItSucksToBeTheChosenOne meant to be weapons of destruction]] before eventually having to use replicas of their weapons]])
* [[ComicBook/DoctorStrange Shuma-Gorath]] vs. [[ComicBook/JusticeLeagueOfAmerica Starro]] (Marvel vs. DC fight of powerful entities with similar physical traits (having one eye and tentacles) who seek to rule over everyone)
* [[WesternAnimation/IceAge Sid]] vs. [[Franchise/StarWars Jar Jar]] (bumbling {{Plucky Comic Relief}}s who were casted out then joins the protagonists who saved their lives)
* [[Franchise/SonicTheHedgehog Silver the Hedgehog]] vs...
** [[Franchise/DragonBall Trunks]] (Spiky-haired heroes who traveled to the past to kill an entity responsible for the BadFuture they come from and have super forms)
** [[VideoGame/CrashBandicoot Tawna Bandicoot]] (Animalistic heroes who traveled from a BadFuture to aid the protagonist in fighting a threat they originally failed to defeat)
* [[ComicBook/GreenLantern Sinestro]] vs...
** [[Franchise/BlazBlue Yuuki Terumi]] (Former heroes who betrayed their allies for their own benefit, lead evil organizations, get more powerful the more people fear them, and become beast-like entities in their most powerful state [Parallax for Sinestro, Susanoo for Terumi)
** [[Literature/{{It}} Pennywise]] (Powerful beings that both embody fear and get stronger the more people fear them)
* [[VideoGame/DarkSouls Sif]] vs. [[Franchise/{{Pokemon}} Zacian]] (Giant dogs who fight with swords that they [[CutlassBetweenTheTeeth hold in their mouths]])
* [[Franchise/{{Castlevania}} Simon Belmont]] vs...
** [[VideoGame/BloodstainedRitualOfTheNight Miriam]] ([[WhipItGood Whip-wielding]] demon slayers of 2D action games who are affected by a curse that slowly kills them. Also a case of original vs SpiritualSuccessor.)
** [[VideoGame/GhostsNGoblins Sir Arthur]] (protagonists of NintendoHard horror-themed action platformer franchises)
* [[WesternAnimation/HeManAndTheMastersOfTheUniverse Skeletor]] vs. [[WesternAnimation/ThunderCats Mumm-Ra]] (undead-themed villains whose respective archenemies (He-Man and Lion-O) have already fought each other in Death Battle)
* [[Franchise/TheLegendOfZelda Skull Kid]] vs. [[Franchise/SonicTheHedgehog Infinite]] (Mask-wearing antagonists from Japanese video games that were once unassuming members of their species until gaining an artifact that can warp reality [Majora for Skull Kid, the Phantom Ruby for Infinite])
* [[{{Manga/Berserk}} Skull Knight]] vs. the [[Franchise/FateSeries First Hassan]] (Powerful, imposing knights who are coated in armor [including a skull-like helmet], existed for centuries, are not afraid to kill, are gruff with a kind heart, save the protagonist from dark deities, and are referred to with royal aliases)
* [[WesternAnimation/PAWPatrol Skye]] vs. [[WesternAnimation/PJMasks Owlette]] (Pink-clad high flyers from two popular preschool shows that actually have plenty of stuff that would be useful in combat. Both of them also have wind attacks, and the original female members of their respective teams)
* [[VideoGame/TeamFortress2 The Sniper]] vs...
** [[Franchise/LupinIII Daisuke Jigen]] (Calm gunslingers who keep their heads and hats down while acting as snipers for their teams)
** [[VideoGame/{{Overwatch}} Ana Amari]] (Snipers from rival team-based shooters)
** [[VideoGame/{{Overwatch}} Hanzo Shimada]] (Same as above, but with the added difference of that the former uses a more modern rifle while the latter uses a traditional bow)
** [[VideoGame/BattleBorn Marquis]] (snipers from hero shooters, with the former being an honorable figure who is mistaken as a common criminal while the latter is a sadistic serial killer with the appearance of a gentleman)
* [[VideoGame/MetalGear Solidus Snake]] vs. [[Manga/FullmetalAlchemist Führer King Bradley]] (One-eyed leaders of military groups who seek to defend their country and wield swords)
* [[WesternAnimation/AvatarTheLastAirbender Sokka]] vs. [[Manga/OnePiece Usopp]] (Both are funny and sharp-witted characters who grew up in a village where they lead children to be warriors and started out as comic-relief only to become competent warriors in their own way despite lacking the standard abilities of their respective series)
* [[VideoGame/{{Overwatch}} Soldier: 76]] vs...
** [[VideoGame/TeamFortress2 The Soldier]] (Rocket-launching soldiers who also have "soldier" in their alias from rivalling team-based soldiers, with the former having regrets about his past while the latter embraces it)
** [[WesternAnimation/TheIncredibles Mr. Incredible]] (Once popular heroes who became outcasts and biligantes after the downfall of heroic organizations and the populace growing to dislike them, with the former attacking criminals and resenting the world and his past while the latter saved lives in secret and longing to become loved by the masses again)
* [[VideoGame/{{Overwatch}} Sombra]] vs...
** [[VideoGame/{{Paladins}} Skye (Paladins)]] (purple-clad {{Stealth Expert}}s who utilize a cloaking device)
** [[VideoGame/WatchDogs Aiden Pearce]] (Master hackers from modern video games)
** [[VideoGame/WatchDogs Marcus Holloway]] (Same as above, but also including the connection of them working with a team of anti-heroes)
** [[VideoGame/WatchDogs Wrench]] (Same as above)
* [[Franchise/{{Godzilla}} SpaceGodzilla]] vs. [[Franchise/UltraSeries Ultraman Belial]] (Dark reflections of classic kaiju-fighting heroes who were corrupted by extraterrestrial meddling)
* ComicBook/SpiderManNoir vs. [[ComicBook/{{Flashpoint}} Flashpoint Thomas Wayne]] (DarkerAndEdgier AlternateUniverse AntiHero versions of Spider-Man and Batman respectively)
* [[Anime/CowboyBebop Spike Spiegel]] vs...
** [[Manga/BlackLagoon Revy]] (Anime mercenaries who are toughened anti-heroes who are often regarded to be among the greatest gun-slingers in anime history, mostly traveling around on a ship sharing the same name of their series. Both are part of a 4-person crew of other outlaws where they have the designated niche as the main marksmen; said crew composes of a big burly guy, a techie, and a new recruit whom they initially didn't get along with but then they eventually become a sort of love interest. Additionally, both have nicknames based on their fighting styles ("Swimming Bird" and "Two-Hands") and are often seen smoking a cigarette throughout their series in a set-up that is basically a "slice-of-life but with guns" premise, fighting against mob crews, teaming up with other bounty hunters, and completing life-risking odd job missions)
** Anime/SpaceDandy (SpaceWestern protagonists made by Creator/StudioBones)
** [[WesternAnimation/TheVentureBrothers Brock Samson]] (OneManArmy companions)
* [[VideoGame/KillerInstinct Spinal]] vs...
** [[VideoGame/SoulSeries Cervantes de Leon]] (Undead pirates from fighting games, with the former being a hero and the latter a villain)
** [[VideoGame/BattleMonsters Fangore]] (fighting game skeletons with swords)
** [[VideoGame/MediEvil Sir Daniel Fortesque]] (skeletal swordsmen)
* [[Franchise/TeenageMutantNinjaTurtles Splinter]] vs. [[WesternAnimation/KungFuPanda Shifu]] (rodent {{Old Master}}s and expert martial artists)
* WesternAnimation/SpongeBobSquarePants vs. [[VideoGame/TheLegendaryStarfy Starfy]] (Protagonists of children's media who are sea animals, are more powerful than they appear, and commonly aid others in need, with the former being a standard, working-class adult while the latter is a child belonging to royalty)
* [[Series/LazyTown Sportacus]] vs...
** [[VideoGame/BarkleyShutUpAndJamGaiden Charles Barkley]] (sports-themed superheroes [the latter retains his superpowered AdaptationalBadass status])
** [[WesternAnimation/PAWPatrol Chase]] (blue superhero speedsters who save lives, use tennis balls as weapons, have young boys and girls to help them, are heavily associated with a pink girl, mainly protect a town, and oppose a goofy villain dressed in purple)
* [[VideoGame/FiveNightsAtFreddys Springtrap]] vs...
** [[Franchise/{{Danganronpa}} Junko Enoshima]] (Murderous, mysterious masterminds who corrupted a seemingly innocent place to serve as the launchpad for their schemes, use a mascot to mask their identity, returned from the dead in a cybernetic form, and are the {{Greater Scope Villain}}s of their series)
** [[Film/ChildsPlay Chucky]] (Serial killers who are trapped in a non-human body of a normally innocent object [William Afton/Springtrap being in the body of an animatronic while Charles Lee Ray/Chucky is in the body of a doll])
* [[VideoGame/TeamFortress2 The Spy]] vs...
** [[VideoGame/AmongUs The Imposter]] (stealthy killers)
** [[VideoGame/{{Dota2}} Riki]] (Valve characters who're invisible backstabbers)
** [[VideoGame/{{Hitman}} Agent 47]] (Expert assassins who use stealth to their advantage)
** [[VideoGame/{{Overwatch}} Sombra]] (Stealth-based fighters from rival team-based shooters who specialize in sabotaging the enemy team)
* [[VideoGame/FinalFantasyVIII Squall Leonhart]] vs...
** [[WebAnimation/{{RWBY}} Ruby Rose]] (Protagonists who train at an academy for warriors and wield blade-gun hybrid weapons)
** [[WebAnimation/{{RWBY}} Qrow Branwen]] (Gun blade wielding swordsmen who seem to be born unluckly on a quest to save the world from an evil witch)
** [[Franchise/{{Persona}} Tatsuya Suou]] ([[TheStoic Stoic]], sword-wielding protagonists with a [[AnimalMotifs lion motif]], who are later discovered [[spoiler:to have had a childhood friendship with their party members that they've all forgot due to a traumatic event]])
** [[Anime/ShamanKing Yoh Asakura]] (Warriors who use spirits to enhance themselves)
** [[Videogame/Persona4 Yu Narukami]] (Leaders of a group of teens who fight with summons)
* [[VideoGame/KirbyPlanetRobobot Star Dream]] vs. [[VideoGame/{{Bayonetta}} Jubileus]] ([[RealityWarper Reality-warping]] [[FinalBoss final bosses]] planning to wipe out all life in the universe)
* [[WesternAnimation/MyLittlePonyFriendshipIsMagic Starlight Glimmer]] vs. [[WesternAnimation/TheLegendOfKorra Amon]] (Villains who despise individuality and take it away. Though Starlight is reformed and moved on, Amon embodies her biggest inner demon)
* [[WesternAnimation/{{Archer}} Sterling Archer]] vs...
** Film/AustinPowers ({{Deconstructive Parod|y}}ies of Film/JamesBond)
** [[WesternAnimation/AmericanDad Stan Smith]] (Anti heroes with ties to secret agencies)
* [[VideoGame/{{Minecraft}} Steve]] VS...
** [[VideoGame/{{Pikmin}} Captain Olimar]] (explorers of open-world games)
** [[VideoGame/LittleBigPlanet Sackboy]] (world creators)
** [[VideoGame/{{Terraria}} The Terrarian]] ([[TheStoic Emotionless]] [[PlayerCharacter player characters]] who explore and fight against a world trying to kill them by gathering materials and making weapons and houses)
** [[WesternAnimation/TheLEGOMovie Emmet]] (Blocky protagonists who can create anything)
* [[Anime/DarlingInTheFranxx Strelizia]] vs. [[Anime/NeonGenesisEvangelion EVA-02]] (Bio-engineered mechas by teenage girls with traumatic experiences and are associated with the number 2)
* [[Series/SpiderManJapan Supaidaman]] vs...
** Anime/BatmanNinja (Japanese versions of Spider-Man and Batman respectively)
** [[Series/Batman1966 Sixties Batman]] (Less serious and more goofy versions of Spider-Man and Batman respectively)
* [[ComicBook/TheAvengers Super-Adaptoid]] vs. [[ComicBook/JusticeLeagueOfAmerica Amazo]](Marvel vs. DC fight of robots who fight against and copy the powers of an entire team of superheroes)
* [[ComicBook/AmalgamUniverse Super Soldier]] vs. [[ComicBook/InfinityWars2018 Soldier Supreme]] (alternate versions of Captain America amalgamated with different superheroes)
* ComicBook/SwampThing vs. ComicBook/ManThing (Marvel vs. DC battle of powerful swamp monsters made of greenery and can control plants with "-Thing" in their names)
[[VideoGame/{{Warcraft}} Sylvanas Windrunner]] vs. [[VideoGame/StarCraft Sarah Kerrigan]] (Female protagonists turned antagonists from video game series owned by Creator/BlizzardEntertainment, being once noble warriors who were corrupted by dark forces to become a major antagonist in their series)
[[Franchise/{{Terminator}} T-1000]] vs. [[Film/TheThing1982 The Thing]] (Morphing, mutating monsters from movies who disguise themselves as people)
* [[WesternAnimation/KungFuPanda Tai Lung]] vs...
** [[WesternAnimation/{{Ninjago}} Morro]] (Former students of the BigGood who were raised under the belief that they were TheChosenOne, only to get rejected for the role, leading to them performing a FaceHeelTurn that results in their imprisonment, which they escape from during the events of the story)
** [[WesternAnimation/AvatarTheLastAirbender Ty Lee]] (kung fu villains who use PressurePoint attacks)
* [[VideoGame/SoulSeries Taki]] vs...
** [[VideoGame/DeadOrAlive Kasumi]] ({{Fanservice}}y kunoichi considered iconic their respective fighting game series)
** [[VideoGame/SenranKagura Asuka]] (Female ninjas who are protagonists and [[Fanservice are known for being sexual]])
* [[VideoGame/SoulSeries Talim]] vs...
** [[VideoGame/{{Tekken}} Josie Rizal]] (Filipino characters from Creator/BandaiNamcoEntertainment games)
** [[VideoGame/SamuraiShodown Nakoruru]] (Protectors of Nature)
** [[Franchise/{{Persona}} Yosuke Hanamura]] (teenagers who [[DualWielding dual wield]] bladed weapons, use wind-based magic that they can use for both [[BlowYouAway attack]] and [[HealingWinds support]], and who [[FragileSpeedster make up for their poor defense by being extremely fast]])
* [[LightNovel/SagaOfTanyaTheEvil Tanya von Degurechaff]] vs...
** [[VideoGame/GranblueFantasy Cagliostro]] (Brilliant, [[CuteAndPsycho shocking vicious]] magicians who are men trapped in the bodies of little girls of small stature with blond hair)
** [[Manga/OnePiece Akainu]] (Cruel, magical enforcers of dictatorial organizations, with the former being unassuming but truly wicked while the latter plays his appearance straight)
** [[Manga/{{Hellsing}} Alexander Anderson]] (Same as above)
** [[Anime/IzettaTheLastWitch Izetta]] (Militaristic magical girls fighting in world wars, with the former being a villainous protagonist who fights for German forces while the latter is a hero who fights against them)
** [[Manga/{{Hellsing}} Seras Victoria]] (Female enforcers of organizations who use both magic and traditional machinery, with the former being a vicious and villainous figure who serves a dictatorial organization while the latter is a hero who fights against one)
* [[WebAnimation/MetaRunner Tari]] vs. [[WesternAnimation/GlitchTechs Miko Kubota]] ([[GamerChick Gamer Chicks]] that have AmbiguouslyHuman origins and wear an advanced technological armwear attached to them that allows them to access and scan various video game data and have interacted with various video game characters and their worlds and has even befriended a video game character that has come to life in the real world. Both are also taken in by their corporations/companies for their unique and odd abilities and have to deal with the number one hot-headed gaming champion rival who are also on the same team as them. Both also have wielded a hammer at one point)
* [[Franchise/MarvelUniverse Taskmaster]] vs. [[Manga/ShuumatsuNoWalkureRecordOfRagnarok Kojiro Sasaki]] (master swordsmen who've fought with some of the greatest warriors in their worlds, copying their moves and using them to their fullest advantage)
* [[Manga/AkameGaKill Tatsumi]] vs. [[Franchise/FateSeries Sieg]] (Young knights who can summon incredibly durable armor derived from a dragon that they obtained from the sacrifice of another hero, can turn invisible, have powerful dragon-related weapons, and can transform into more draconic forms the more power they use with the caveat of them possibly turning into dragons with using them)
* [[VideoGame/{{Warcraft}} Thrall]] vs. [[TabletopGame/Warhammer40000 Ghazghkull]] (Fantasy vs. Sci-Fi fight of orcs who lead an army of their race)
* [[Manga/{{Bleach}} Tier Harribel]] vs. [[LightNovel/HighSchoolDxD Xenovia Quarta]] (Calm and cool yet {{Fanservice}}y swordswomen who lead organizations and fight against evil entities, with Tier being a supernatural entity while Xenovia hunts them)
* [[WesternAnimation/TheFairlyOddParents Timmy Turner]] vs. [[ComicStrip/CalvinAndHobbes Calvin]] (Children who team up with invisible imaginary friends whose greatest weapon is their imagination)
* [[Franchise/{{Persona}} Tohru Adachi]] vs. [[Manga/JoJosBizarreAdventure Yoshikage Kira]] (serial killers from the fourth entries of their respective series aided by familiar-like beings)
* [[Manga/MyHeroAcademia Tomura Shigaraki]] vs...
** [[Manga/{{Naruto}} Kabuto Yakushi]] (Teenage villains with tragic backstories before becoming mentees of a feared villain who learn to step out of their mentor's shadow and gain the ability to use other people's special abilities)
** [[WebAnimation/{{RWBY}} Cinder Fall]] (Antagonists who became resentful of heroism due to feeling neglected by them and desire to change the status quo to fit their desires by following the command of another villain)
** [[Manga/{{Naruto}} Obito Uchiha]] (The proteges of a villain from a manga/anime series from Magazine/ShonenJump who were once heroes but turned away from it after feeling wronged, now desiring to change society to their desires)
* [[Film/Scarface1983 Tony Montana]] vs. [[Series/TheWire Omar Little]] (one of fiction's most famous drug dealers against a man famous for robbing them)
* [[LightNovel/ACertainMagicalIndex Touma Kamijou]] vs...
** [[Manga/{{Bleach}} Moe Shishigawara]] (Powerful punchers, Touma having bad luck while Moe has good luck)
** [[Manga/MyHeroAcademia Izuku Midoriya]] (Regular teenage boys granted extraordinary superpowers)
** [[LightNovel/HighSchoolDxD Issei Hyoudou]] (People with dragons inside them, with Touma has an UnwantedHarem while Issei is a HaremSeeker)
** [[Franchise/FateSeries Shirou Emiya]] (CluelessChickMagnet amnesiacs with chronic hero syndrome and unique powers)
** [[Manga/BlackClover Asta]] (young heroes with a strong sense of justice who can cancel magical powers)
* [[Toys/{{Jewelpet}} Tour]] vs. [[Franchise/{{Shrek}} Puss in Boots]] (Green-eyed Spanish cat thieves whose greatest weapons are their eyes: Tour [[MagicalEye casts spells with his]] while Puss mesmerizes others with his PuppyDogEyes. Both cats are also romantically linked to Ruby and Kitty Softpaws respectively.)
* [[VideoGame/NoMoreHeroes Travis Touchdown]] vs...
** [[VideoGame/MadWorld Jack Cayman]] (protagonists of ultra-violent UsefulNotes/{{Wii}}-exclusive games)
** ComicBook/ScottPilgrim (nerd fighters that can turn enemies into coins)
** [[ComicBook/GuardiansOfTheGalaxy Star-Lord]] (Anti-heroic bounty-hunters with a cocky personality, fight their own family members, are often associated with a certain type of media, and go to space to fight aliens)
** [[Manga/MyHeroAcademia Overhaul]] (assassins of the superhuman variety)
* [[VideoGame/{{Tyrian}} Trent Hawkins]] vs. [[VideoGame/RaptorCallOfTheShadows The Raptor Mercenary]] (pilots of [[MadeOfIron surprisingly durable]] ShootEmUp craft)
* [[Anime/{{Symphogear}} Tsubasa Kazanari]] vs. [[Franchise/{{Persona}} Yukari Takeba]] (Teenage celebrities who lead a double life fighting monsters that can only be killed by people with special abilities, works on a team alongside other ability users, becomes emotionally distant after the death of a loved one, and initially resents another team member who inherited the loved ones power, but eventually gets over it and becomes friends with them)
* [[Manga/Reborn2004 Tsunayoshi Sawada]] vs. [[Manga/{{Beelzebub}} Oga Tatsumi]] (high school students roped into business that's way over their heads)
* [[Manga/MyHeroAcademia Tsuyu Asui]] vs. [[ComicBook/XMen Toad]] (Mutants with amphibian abilities)
* [[WebAnimation/{{RWBY}} Tyrian Callows]] vs. [[WebAnimation/MadnessCombat Tricky]] (lunatic killers from web series renowned for their fast-paced, fluid battle scenes)
* [[VideoGame/DeadRising Tyrone King]] vs...
** The [[VideoGame/MadWorld Black Baron]] (Antagonists who are large orchestrators of televised events that put a spotlight on general bloodbaths)
** [[WebAnimation/{{RWBY}} Roman Torchwick]] (Wealthy, power-hungry manipulators who seek to cheat their way into becoming powerful)
* [[Manga/{{Bleach}} Ulquiorra Cifer]] vs. [[Franchise/KingdomHearts Xemnas]] (Humanoid beings of darkness and emptiness who serve evil organizations and seek to become human, acquiring it in death)
* [[Franchise/UltraSeries Ultraman]] vs...
** Series/ZoneFighter (Similar-looking superheroes with a wide array of technological abilities who grow to massive sizes to fight kaiju and save the planet)
** [[Franchise/{{Godzilla}} Jet Jaguar]] (Same situation as above, although using a more iconic character)
* [[VideoGame/{{Undertale}} Undyne]] vs...
** The [[WebComic/OnePunchMan Deep Sea King]] (Fishwoman who's a parody of [[ShonenDemographic Shonen]] heroes vs. Fishman who's a parody of Shonen villains)
** [[Franchise/KingdomHearts Xaldin]] (Fighting with multiple lances)
** [[VideoGame/MegaMan9 Splash Woman]] (aquatic {{Action Girl}}s who fight with similar weapons)
** [[Franchise/{{Kirby}} Bandana Waddle Dee]] (Spear users who both serve a king)
** [[WesternAnimation/StevenUniverse Pearl]] (Spear-wielders who serve as major protagonists in a group)
* WesternAnimation/UncleGrandpa vs. [[WesternAnimation/CoconutFredsFruitSaladIsland Coconut Fred]] (Childlike entities from cartoons with reality warping powers)
* [[Manga/JoJosBizarreAdventure Vanilla Ice]] vs. [[Manga/{{Baoh}} Walken]] (Characters created by Creator/HirohikoAraki who are long-haired, deranged minions who can erase matter)
* [[Franchise/StreetFighter Vega]] vs. [[VideoGame/SoulSeries Voldo]] (Villainous fighting game characters who are minions, are from European countries [Vega being French while Voldo is Italian] attack using bladed weapons, and are seeking for something [Vega seeking beauty while Voldo seeks the Soul Edge], with Vega dating those he deems ugly while Voldo has a very unsightly appearance)
* [[WesternAnimation/Ben10 Vilgax]] vs. [[Franchise/{{Superman}} General Zod]] (Former alien generals who betrayed their race following their banishment to an extradimensional prison for disobedience who became intergalactic warlords who attempted to conquer Earth)
* [[ComicBook/{{Spawn}} Violator]] vs...
** [[Literature/{{It}} Pennywise]] (Sadistic and cruel monsters who take the form of {{Monster Clown}}s)
** [[WebAnimation/MadnessCombat Tricky]] (Same as above)
* [[Franchise/PowerRangers Venjix/Evox]] vs...
** [[WesternAnimation/CodeLyoko XANA]] (Evil computer viruses)
** [[VideoGame/SystemShock SHODAN]] (Same as above)
* [[VideoGame/TalesOfBerseria Velvet Crowe]] VS...
** [[VideoGame/Drakengard3 Zero]] ({{Action Girl}}s with demonic powers whose goals are to kill someone personal to them.)
** [[VideoGame/FinalFantasyXV Noctis Lucis Caelum]] (Protagonists from the latest entries of their franchises who're motivated by revenge.)
** [[Franchise/{{Persona}} Akira Kusuru/Ren Amamiya/Joker]] (Protagonists from the latest entries of their franchises who have criminal records that were wrongly convicted and are against those that are [[VillainWithGoodPublicity Villains that look good to the public]])
** [[VideoGame/DevilMayCry Nero]] (People with demonic murder-arms who oppose the local CorruptChurch)
* [[WesternAnimation/HotWheelsBattleForce5 Vert Wheeler]] vs. [[WesternAnimation/{{Motorcity}} Mike Chilton]] (leaders of a FiveManBand that have weaponized cars)
* [[VideoGame/DragaliaLost Volk]] vs. [[Franchise/TouhouProject Seija Kijin]] (Two antagonistic individuals whose goals involve having the weak dominate the strong.)
* [[Series/BreakingBad Walter White]] vs. [[Franchise/{{Saw}} John Kramer]] (Old men with crappy life who become infamous not-so-well-intentioned criminals with an iconic alias after being diagnosed with cancer, rather weak physically but are genius and have engineering skills)
* [[Manga/JoJosBizarreAdventure Wamuu]] vs. [[Franchise/StreetFighter Necalli]] (Ancient warriors who seek to fight strong opponents, with one being an honorable fighter while the other is a vicious, honorless monster)
* [[Manga/OnePiece Whitebeard]] vs...
** [[Manga/TheSevenDeadlySins Escanor]] (Huge, muscular, charismatic, mustached men full of pride, who are both feared, as well as respected throughout the world for their might and pride, and also serve as support for the protagonist, [[spoiler:even after their unfortunate passing]])
** [[Manga/{{Bleach}} Genryusai Yamamoto]] (extremely powerful old men who serve as leaders)
** [[Manga/HunterXHunter Isaac Netero]] (same reason as above)
* [[Literature/TheChroniclesOfNarnia White Witch]] vs. [[Literature/TheWonderfulWizardOfOz Wicked Witch of the West]] (evil witches)
* ComicBook/{{Wiccan}} vs. [[Podcast/TheAdventureZone Taako]] (powerful gay wizards)
* [[WesternAnimation/LooneyTunes Wile E. Coyote]] vs. [[Franchise/TomAndJerry Thomas "Tom" Cat]] (Animalistic, mute, and villainous protagonists from Creator/WarnerBros who try and fail time-and-time again to defeat their rivals using technology)
* [[VideoGame/{{Overwatch}} Winston]] vs. [[ComicBook/TheFlash Gorilla Grodd]] (hyper-intelligent gorillas)
* [[Franchise/StarFox Wolf]] vs...
** [[Franchise/MortalKombat Kano]] (Ruthless, one-eyed mercenaries and leaders of criminal groups that are constantly pursued by government-employed agents who are their rivals. Both also once teamed up with their enemies to take out a bigger threat than them)
** [[Franchise/KungFuPanda Tai Lung]] (Grey-colored rivals to the main protagonist who serve as dark reflections of them, with the former using futuristic weaponry while the latter uses martial arts and seeks magical power)
* WesternAnimation/WordGirl vs. [[WesternAnimation/MiraculousLadybug Ladybug]] (Teenage female superheroes who have a large cast of villains and have secret identities that they must keep from their friends.)
* [[Series/StarTrekTheNextGeneration Worf]] vs. [[Franchise/MassEffect Urdnot Wrex]] (space opera {{proud warrior race guy}}s)
* ComicBook/{{X 23}} vs...
** [[WesternAnimation/DannyPhantom Dani Phantom]] (younger {{Opposite Sex Clone}}s who are more than capable of being able to fight on par with their originals)
** [[Franchise/MortalKombat Mileena]] (Clones who have a major physical difference from the original that differentiates them, and are extremely violent in combat)
* The [[Franchise/{{Alien}} Xenomorph]] vs. the [[Series/StrangerThings Demogorgon]] (Monstrous, eyeless creatures with strange months who are subservient to a larger monster, with the former being a biological creature while the latter is supernatural)
* [[Manga/{{Bleach}} Yhwach]] vs...
** [[Manga/{{Naruto}} Kaguya Ōtsutsuki]] (Powerful antagonists from manga/anime series who existed for millennia and return in their series present to enact their evil schemes)
** [[Franchise/KingdomHearts Master Xehanort]] (Major antagonists who cause a large amount of events in their series, lead an army of shadows, and fight against a hero who fights against said shadows)
** [[VideoGame/XenobladeChronicles1 Zanza]] (Fate-changing, god-like beings who serve as the final antagonist of their works, were driven to insanity by a desire of power, and seek to destroy humanity)
** [[VideoGame/StarWarsTheOldRepublic Darth Vitiate]] (Leaders of dark empires who return after years of absence to attack the world, gain power through consuming the lifeforce of others, were originally powerless but gained power through their deeds [including killing their fahers] to the point they are now referred as god-like beings, constantly return from the dead, and gained enough power to become nearly-unstoppable concepts of destruction before meeting their ends at the hands of [[spoiler:their children]])
* [[Anime/{{GurrenLagann}} Yoko Littner]] vs. [[VideoGame/GodEater Alisa Ilinichina Amiella]] (Female marksmen who fight against invading monsters)
* [[Manga/{{Bleach}} Yoruichi Shihouin]] vs...
** [[Creator/DCComics Black Lightning]] (Electromancers who grew up as very talented individuals who exceeded in almost every category and became teachers to a group of teens who needed their guidance. Both are also not fully recognized as heroes as they are more akin to vigilantes associated with heroic groups and still do the right thing)
** [[Manga/{{Naruto}} Minato Namikaze]] (Insanely fast ex-leaders that were mentors to other powerful characters in the series and also reveal hidden power in the last arc of their series)
** [[Manga/YuYuHakusho Younger Toguro]] vs. [[Manga/{{Berserk}} Nosferatu Zodd]] (Muscular, powerful rivals to heroes from classic manga/anime who seek to fight strong opponents and are honorable despite their status as villains)
* [[Franchise/YuGiOh Yugi Muto]] vs...
** [[Anime/PokemonTheSeries Ash Ketchum]] (Monster summoners from early 2000s anime (that were dubbed by 4Kids) that summon monsters to fight other monsters in 1v1 battles, with both series eventually spawning popular card games based on them)
** [[Manga/CardCaptorSakura Sakura Kinomoto]] (Monster summoners who summon monsters with cards to fight against other monsters)
** [[Literature/TheKaneChronicles Carter Kane]] (Teens involved in ancient Egyptian magic and realms)
* [[Manga/BlackClover Yuno]] vs...
** [[Manga/FairyTail Wendy]] (Orphan children skilled in [[BlowYouAway Wind Magic]] that had a backstory they weren't fully aware of)
** [[WesternAnimation/TheLegendOfKorra Zaheer]] (Clever and innovative Masters of {{Blow You Away}} that go against their country's status quo)
** [[Manga/JoJosBizarreAdventure Wamuu]] (Skilled fighters that use {{Blow You Away}} and show respect toward the main character more than most and {{Undying Loyalty}} towards their leaders despite evidence against it [Vangeance letting Patry wreak hell on the kingdom, Kars having no real sense of honor])
** [[LightNovel/ReZero Emilia]] ({{Chaste Hero}} Spirit users subject to {{All of the Other Reindeer}} which hinders their desires to rule over their country. They are very close with {{The Hero}} but aren't afraid to call them out on their flaws. They also use their magic for {{Spontaneous Weapon Creation}} albeit vastly preferring [[HeroesPreferSwords swords]]. Finally, they have elven ancestry [Emilia being a half-elf, Yuno having the soul of a half-elf inside him since birth] and are picked up by villains who themselves were to {{All of the Other Reindeer}} for their own goals [Patry, and by extension Vangeance to revive all the elves, Roswaal to revive Echidna)
* [[Manga/FutureDiary Yuno Gasai]] vs....
** [[VideoGame/YandereSimulator Ayano Aishi]] ({{Yandere}} vs. {{Yandere}})
** [[VisualNovel/HigurashiWhenTheyCry Rena Ryuugu]] ({{Yandere}} vs. CuteAndPsycho)
** [[LightNovel/ShakuganNoShana Shana]] ({{Tsundere}}s vs. {{Yandere}}s)
** ComicBook/HarleyQuinn (another case of {{Yandere}} vs. {{Yandere}})
* [[VideoGame/TalesOfVesperia Yuri Lowell]] vs...
** [[VideoGame/FireEmblemPathOfRadiance Ike]] (Swordfighters who lead their own band of mercenaries from fantasy [=RPGs=])
** [[ComicBook/XMen Psylocke]] (Heroic swordfighters with long, purple hair)
** [[VideoGame/GenshinImpact Diluc]] (Former knights who left an organization and later fought against it following them noticing their corruption, including that of sweeping the deaths of their masters under the rug)
* [[Franchise/{{Persona}} Yusuke Kitagawa]] vs. [[VideoGame/DragonQuest Sylvando]] (Eccentric RPG party members who are the fifth members of their team, have issues with their fathers, and dedicate their lives to the arts [Yusuke for painting, Sylvando for performing])
* [[Manga/YuYuHakusho Yusuke Urameshi]] vs...
** [[Manga/HunterXHunter Gon Freecss]] (Protagonists of manga created by Creator/YoshihiroTogashi and published by Magazine/ShonenJump)
** Manga/InuYasha (demonic heroes from retro anime who fight against evil spiritual entities)
** Series/KamenRiderGhost (teenagers who gained ghost superpowers after dying)
** [[Franchise/TouhouProject Reimu Hakurei]] (Humans [or at least originally human] with strong magical powers who fight against evil spiritual beings in realms made for them)
* [[Franchise/BlazBlue Yuuki Terumi]] vs. [[LightNovel/DateALive Isaac Westcott]] (Extremely powerful antagonists who delivered a countless amount of crimes ForTheEvulz)
* [[Franchise/DragonBall Zamasu]] vs...
** [[Franchise/FateSeries Goetia]] (God-like entities who once watched over humanity before they came evil after growing discontent with them [with Zamasu being disgusted by humanity and seeking to destroy it while Goetia desires to "save" it from its flaws], seek to destroy the universe to recreate it to their liking, stole the bodies of mortals, have multiple forms [including one they obtain after [[FusionDance fusing with an alternate version themselves]] to defeat the heroes], wear important rings, and use powerful wish-granting tools in their quest for domination)
** [[Manga/SaintSeiya Hades]] (Powerful deities who seek to destroy humanity)
** [[Franchise/{{Digimon}} Lucemon]] (Powerful, evil deities who [[FallenHero were once good]] but now seek to destroy the world to remake it in their image)
* [[Franchise/{{Pokemon}} Zekrom]] vs. [[Franchise/YuGiOh Red-Eyes Black Dragon]] (Legendary black dragon OlympusMons who can [[FusionDance fuse together]] with other, similar dragons to become even more powerful)
* [[Series/PowerRangersZeo Zeo Megazord/Super Zeo Megazord]] vs. [[Anime/{{Voltron}} Vehicle Voltron]] (The 2nd Power Ranger team vs the 2nd/Other Voltron Force as a sequel)
* [[VideoGame/GodOfWar Zeus]] vs. [[VideoGame/AsurasWrath Deus]] (Prideful, electrokinetic deities who lead a group of deities, fight against a god-slayer who seeks revenge on the gods for killing their families)
* [[WesternAnimation/InvaderZim Zim]] vs...
** [[VideoGame/DestroyAllHumans Crypto]] (Mini alien invaders that want to TakeOverTheWorld and uses many various gadgets to do so)
** [[WebAnimation/HelluvaBoss Moxxie]] (Two small inhuman invaders that are voiced by Creator/RichardStevenHorvitz)
** [[Animation/BoBoiBoy Adu Du]] (Green aliens with funny robot sidekick; they are looked down back on their home planet and go to Earth in order to gain fellow aliens' respect; their primary foe is a young boy)
