History ThatOneLevel / AmateurSurgeon

* The Mystery Boss is a complete pain in the ass. Poison builds up quickly, and it's incredibly difficult to syringe out all the poison before it multiplies in another area. This is already hard enough, but add on the fact that every use of the syringe makes a small cut, the bee flies around and lands for just a second, and the fact that the time window to complete the surgery is incredibly small... be prepared to replay the surgery over and over until you complete it.
** It's even worse in the mobile versions, since the flashlight (which is always where your mouse cursor is on PC) is controlled via ''tilting the phone''. As if the surgery wasn't difficult enough...

* Level 42 (Karl Puccino from ''AS1'') was already hard in its original version, but this revamp amplifies it for how little time you have to complete it. You have to find eight coffee bags hidden, scratch out the pus, vacuum up all the blood and pus, and stitch up the wounds in the span of ''one minute and thirty seconds''. Not helping is the fact that having too much pus onscreen will rapidly decrease your heart rate, so it's recommended to vacuum up one or two piles of it at a time. If you want a shot at beating this level, you better have some memory of where the coffee bags are and be fast.

* Level 84 (Junkyard Guts' second surgery from ''AS1'') is extremely hard if you play on Sudden Death mode or try to go for a no-hit run. One of the tasks is pulling out five needles in a row from the time bomb, which all are very narrow and require a lot of precision and accuracy to successfully pull out without harming Guts.

* Dr. Bleed's second surgery. All of the various hard-as-hell surgeries in the game (which were usually made hard by GuideDangIt moments) tend to become much easier once you know the trick behind them. This one, on the other hand, is a four-part MarathonLevel against poison, fire, buried chunks of crystal, and finally a tapeworm that takes more hits from the battery to kill than the last tapeworm (and can quickly cause Bleed to... er... bleed out if you're not multi-tasking between cauterizing the cuts it makes and zapping it). And you have just enough time to do it all quickly and flawlessly.

* Napoleon Trotterski. His surgery starts off easy enough, but suddenly ends with you having to spell out words on a "Speak 'N Spell". If you aren't fast enough, the Speak 'N Spell suddenly ''explodes'', leaving flames and burn marks that'll almost certainly obscure the screen and the keys; and if you try to put out the fire/heal the burn marks directly when they're on the keyboard, the game will assume you're hitting the keyboard instead and explode a second time. Not that you'll have any time to put out the fire anyway because the words are coming faster and faster while you're trying to spell them out while not being able to see what the hell you're supposed to be spelling because ''the goddamn fire is in the way.''
** And if you thought that was bad, imagine trying to spell those words without knowing that you can use ''the computer keyboard'' to type them.
** It speaks to the difficulty of this surgery that ''Amateur Surgeon 4'', which otherwise has every level from the previous games sans ''Christmas Edition'', ''omitted'' it from the collection.
* On the iOS version, the Mystery Boss requires you to tilt your device to move a flashlight around. And while you're doing this, there's a bee randomly flying around and only landing for a second in which you have to zap it. The difficult controls and the small time window combined make this unfairly difficult.
** It's not any easier in the PC version. Poison builds up quickly, and while you're trying to clean up the poison in one area, it multiples in another. Meanwhile, that goddamn bee keeps stinging him. And every time you syringe out poison, it makes a small cut. If you lose track of them, the patient's heart rate will plummet.

* The Partner Special for Level 54 (Dwayne Pipe), to where even using the required I.C. Wiener doesn't help that much. Worms are fast and small enemies which makes it very easy to miss them and you have to shock them three times. Also, your heart rate decreases rapidly, so you can't just shock a few of them at a time. Instead, you have to be really quick and shock as many of them as you can in one consecutive try, and if you miss a shot, well, just hope your heart rate isn't close to zero.
* The surgery from the first game that takes place as Level 42 here (Karl Puccino) was already hard in its original version, but this revamp amplifies it for how little time you have to complete it. You have to find eight coffee bags hidden, scratch out the pus, vacuum up all the blood and pus, and stitch up the wounds ''all in the span of one minute and thirty seconds''. Pair that with the fact that having too much pus onscreen will rapidly decrease your heart rate, so it's recommended to vacuum up one or two piles of it at a time. If you want a shot at beating this level, you better have some memory of where the coffee bags are and be fast.
* Level 84 (Junkyard Guts) is extremely hard if you play on Sudden Death mode or try to go for a no-hit run. One of the tasks is pulling out five needles in a row from the time bomb, which all are very narrow and require a lot of precision and accuracy to successfully pull out without harming Guts.
* Level 92 (Useful Brother) and its Partner Special are both ''extremely'' difficult. If the ice ants don't bother you, then the confusing cluster of maladies Max Chaos causes in the Partner Special will.

* Level 84 (Junkyard Guts) is extremely hard if you play on Sudden Death mode or try to go for a no-hit run. One of the tasks is pulling out five needles in a row from the time bomb, which all are very narrow and require a lot of precision and accuracy to successfully pull out without harming the patient.

** It speaks to the difficulty of this surgery that ''Amateur Surgeon 4'', which otherwise has every level from the previous games sans ''Christmas Edition'', '''omitted''' it from the collection.

** It speaks to the difficulty of this surgery that ''Amateur Surgeon 4'', which otherwise has every level from the previous games, ''omitted'' the level from the collection.

* Dr. Bleed's second surgery. All of the various hard-as-hell surgeries in the game (which were usually made hard by GuideDangIt moments) tend to become much easier once you know the trick behind them. This one, on the other hand, is a four-part MarathonLevel against poison, fire, buried chunks of crystal, and finally a tapeworm that takes more hits from the battery to kill than the last tapeworm (and can quickly cause Bleed to... er... bleed out if you're not multitasking between cauterizing the cuts it makes and zapping it). And you have just enough time to do it all quickly and flawlessly.

* Dr. Bleed's second surgery. All of the various hard-as-hell surgeries in the game (which were usually made hard by GuideDangIt moments) tend to become much easier once you know the trick behind them. This one, on the other hand, is a four-part MarathonLevel against poison, fire, buried chunks of crystal, and finally a tapeworm that takes more hits from the battery to kill than the last tapeworm (and can quickly cause Bleed to... er... bleed out if you're not multitasking between cauterizing the cuts it makes and zapping it.) And you have just enough time to do it all quickly and flawlessly.

* Dr. Bleed's second surgery. All of the various hard-as-hell surgeries in the game (which were usually made hard by GuideDangIt moments) tend to become much easier once you know the trick behind them. This one, on the other hand, is a four-part MarathonLevel against poison, fire, buried chunks of crystal, and finally a tapeworm that takes more hits from the battery to kill than the last tapeworm (and can quickly cause Bleed to...er...bleed out if you're not multitasking between cauterizing the cuts it makes and zapping it.) And you have just enough time to do it all quickly and flawlessly.

* Dr. Bleed's second surgery. All of the various hard-as-hell surgeries (which were usually made hard by GuideDangIt moments) tend to become much easier once you know the trick behind them. This one, on the other hand, is a four-part MarathonLevel against poison, fire, buried chunks of crystal, and finally a tapeworm that takes more hits from the battery to kill than the last tapeworm (and can quickly cause Bleed to...er...bleed out if you're not multitasking between cauterizing the cuts it makes and zapping it.) And you have just enough time to do it all quickly and flawlessly.

* Dr. Bleed's second surgery. All the various hard-as-hell surgeries (which are usually made hard by GuideDangIt moments,) tend to be much easier once you know the trick behind them. The 2nd Dr. Bleed surgery, on the other hand, is a four-part MarathonLevel against poison, fire, buried chunks of crystal, and finally a tapeworm that takes more hits from the battery to kill than the last tapeworm (and can quickly cause Bleed to...er...bleed out if you're not multitasking between cauterizing the cuts it makes and zapping it.) And you have just enough time to do it all quickly and flawlessly.

* The surgery from the first game that takes place as Level 42 here (Karl Puccino) was already hard in its original version, but this revamp amplifies it for how little time you have to complete it. You have to find eight coffee bags hidden, scratch out the pus, vacuum up all the blood and pus, and stitch up the wounds ''all in the span of one minute and thirty seconds''. Pair that with the fact that having too much pus onscreen will rapidly decrease your heart rate, so it's recommended to vacuum up one or two piles of it at a time. If you want a shot at beating this level, you better have some memory of where the coffee bags are and you better be fast.

* Napoleon Trotterski. His surgery, starts off easy enough, but suddenly ends with you having to spell out words on a "Speak 'N Spell". If you aren't fast enough, the Speak 'N Spell suddenly ''explodes'', leaving flames and burn marks that'll almost certainly obscure the screen and the keys; and if you try to put out the fire/heal the burn marks directly when they're on the keyboard, the game will assume you're hitting the keyboard instead and explode a second time. Not that you'll have any time to put out the fire anyway because the words are coming faster and faster while you're trying to spell them out while not being able to see what the hell you're supposed to be spelling because ''the goddamn fire is in the way.''

* Napoleon Trotterski. His surgery, starts off easy enough but suddenly ends with the player having to spell out words on a "Speak 'N Spell". If you aren't fast enough, the Speak 'N Spell suddenly ''explodes'', leaving flames and burn marks that'll almost certainly obscure the screen and the keys; and if you try to put out the fire/heal the burn marks directly when they're on the keyboard, the game will assume you're hitting the keyboard instead and explode a second time. Not that you'll have any time to put out the fire anyway because the words are coming faster and faster while you're trying to spell them out while not being able to see what the hell you're supposed to be spelling because ''the goddamn fire is in the way.''

** Dr. Bleed's second surgery. All the various hard-as-hell surgeries (which are usually made hard by GuideDangIt moments,) tend to be much easier once you know the trick behind them. The 2nd Dr. Bleed surgery, on the other hand, is a four-part MarathonLevel against poison, fire, buried chunks of crystal, and finally a tapeworm that takes more hits from the battery to kill than the last tapeworm (and can quickly cause Bleed to...er...bleed out if you're not multitasking between cauterizing the cuts it makes and zapping it.) And you have just enough time to do it all quickly and flawlessly.
** Napoleon Trotterski from the second game. It starts off easy enough but suddenly ends with the player having to spell out words on a Speak 'N Spell. And if you aren't fast enough, the Speak 'N Spell suddenly ''explodes'', leaving flames and burn marks that'll almost certainly obscure the screen and the keys, and if you try to put out the fire/heal the burn marks directly when they're on the keyboard, the game will assume you're hitting the keyboard instead and explode a second time. Not that you'll have any time to put out the fire anyway because the words are coming faster and faster while you're trying to spell them out while not being able to see what the hell you're supposed to be spelling because ''the goddamn fire is in the way.''
*** And if you thought that was bad, imagine trying to spell those words without knowing that you can use ''the computer keyboard'' to type them.
*** It speaks to the difficulty of this surgery that ''Amateur Surgeon 4'', which otherwise has every level from the previous games, ''omitted'' the level from the collection.
** On the iOS version, the Mystery Boss in the second game requires you to tilt your device to move a flashlight around. And while you're doing this, there's a bee randomly flying around and only landing for a second in which you have to zap it. The difficult controls and the small time window combined make this unfairly difficult.
*** It's not any easier in the PC version. Poison builds up quickly, and while you're trying to clean up the poison in one area, it multiples in another. Meanwhile, that goddamn bee keeps stinging him. And every time you syringe out poison, it makes a small cut. If you lose track of them, the patient's heart rate will plummet.
** The Partner Special for Level 54 (Dwayne Pipe) in the 4th game, to where even using the required I.C. Wiener doesn't help that much. Worms are fast and small enemies which makes it very easy to miss them and you have to shock them three times. Also, your heart rate decreases rapidly, so you can't just shock a few of them at a time. Instead, you have to be really quick and shock as many of them as you can in one consecutive try, and if you miss a shot, well, just hope your heart rate isn't close to zero.
** Level 42 (Karl Puccino) is also hard just for how little time you have to complete it. You have to find eight coffee bags hidden, scratch out the pus, vacuum up all the blood and pus, and stitch up the wounds ''all in the span of one minute and thirty seconds''. Pair that with the fact that having too much pus onscreen will rapidly decrease your heart rate, so it's recommended to vacuum up one or two piles of it at a time. If you want a shot at beating this level, you better have some memory of where the coffee bags are and you better be fast.
** Level 84 (Junkyard Guts) is extremely hard if you play on Sudden Death mode or try to go for a no-hit run. One of the tasks is pulling out five needles in a row from the time bomb, which all are very narrow and require a lot of precision and accuracy to successfully pull out without harming the patient.
** Level 92 (Useful Brother) and its Partner Special are both ''extremely'' difficult. If the ice ants don't bother you, then the confusing cluster of maladies Max Chaos causes in the Partner Special will.