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** While Angie and Derek were kidnapped by Delphi, Heinrich openly boast about his plans to use Angie to cultivate a new strain of GUILT, and use Derek as it's first test subject as a punishment for Blackwell's 'betrayal', and the duo for foiling the organisation's plans time and again. Now you know the consequences of what will happen to the two protagonists should you fail the 'surgery' to disable the lock to cell they were held in...

to:

** While Angie and Derek were kidnapped by Delphi, Heinrich openly boast about his plans to use Angie to cultivate a new strain of GUILT, and use Derek as it's first test subject as a punishment for Blackwell's 'betrayal', and the duo for foiling the organisation's plans time and again. Now you know the consequences of what will happen to the two protagonists should you fail the 'surgery' to disable the lock to the cell they were held in...
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** The first episode of Patient Zero starts quietly before the player is forced to see the bleeding face of a woman dying by the Rosalia Virus before it starts spreading out to the people gathering around her.

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A little bit of sorting by game release date and chronological order (please do help with that)


* At first, the operations in ''Under the Knife'' / ''[[VideoGameRemake Second Opinion]]'' are relatively low-tension operations: removing glass from a patient's arm, removing tumors from another patient's stomach, burning away polyps from someone's throat. Might make some players queasy, but nothing really life-threatening happening. However, the operation at [[EstablishingSeriesMoment the end of the first chapter]] is a WhamEpisode, giving you the first life-or-death operation in the game. Defibrillator, done. Remove glass shards from patient's chest area, done. Open up patient and oh god there are shards of glass in his heart too!

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! Shared Examples
* In earlier operations, if you fail an operation, another doctor will simply take over for you, securing the patient's life. However, in later operations, whoever you're playing as is often the only doctor capable of dealing with whatever is inside the patient, which means if your patient's vitals hit 0 (or you [[TimedMission run out of time]]), your patient will outright '''die.'''
* The [[BrutalBonusLevel X missions]] in Under the Knife 1, 2, and Second Opinion not only took all the [[NintendoHard already complicated and stressful]] [[BossBattle GUILT/Neo-GUILT surgeries]] [[UpToEleven up to an entirely new level in terms of difficulty]]. You will be performing them without the by now familiar and perhaps comforting assistance of Angie or any other ally by your side, with only the BigBad taunting you the entire time in the background on futility of your struggle against them. The feeling of isolation can be quite chilling to some.

! Under the Knife and Second Opinion
* At first, the operations in ''Under the Knife'' / ''[[VideoGameRemake Second Opinion]]'' are relatively low-tension operations: removing glass from a patient's arm, removing tumors from another patient's stomach, burning away polyps from someone's throat. Might make some players queasy, but nothing really life-threatening happening. However, the operation at [[EstablishingSeriesMoment the end of the first chapter]] is a WhamEpisode, giving you the first life-or-death operation in the game. Defibrillator, done. Remove glass shards from patient's chest area, done. Open up patient and oh god there are shards of glass in his heart too!



* In ''Under The Knife'' and ''Second Opinion'', there is one operation where your "patient" is a ''time bomb''. Fail to defuse it in time, or [[ParanoiaFuel fail to keep up with its triggering mechanisms/make too many mistakes]], and to nobody's surprise, Derek gets a front-row seat of the bomb's explosion.

to:

* In ''Under The Knife'' and ''Second Opinion'', there There is one operation where your "patient" is a ''time bomb''. Fail to defuse it in time, or [[ParanoiaFuel fail to keep up with its triggering mechanisms/make too many mistakes]], and to nobody's surprise, Derek gets a front-row seat of the bomb's explosion.



* Trauma Team has a pretty scary one in terms of the main threat, which almost puts GUILT and Stigma to shame. The Rosalia Virus causes WAY too many people to die. And when Rosalia is in its active state, they bleed to DEATH through anything with a hole, including their EYES. Sandra Lieberman (The Raging Bomber) demonstrates this as the game gives the player a good close-up of her face as she succumbs to the disease before dying in an explosion.
** Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period. While giving you a touch of AxCrazy provided it spreads to the brain. It also just happens to leave its trademark black bruises in the shape of a freaking CLAW on the organs of most victims, most evidently on the liver, as the virus spreads across the body.
** It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant caterpillar in her ''heart''. The implications that it's the result of Rosalia and the remnants of GUILT mixing together only make it more disturbing.
** The most startling thing about Rosalia? It's not some artificial parasite or bioweapon designed for mass-murder. It's just a regular virus whose existence was not by the hands of madmen but by the random evolutions of nature. It manages to be ''even more dangerous'' and complicated to treat than GUILT and Stigma.
* In Under the Knife 2, Neo-GUILT (particularly Sige) also causes its victims to become AxCrazy.
** Call it {{Narm}} if you must, but Sige-infected Adel demonstrates a rather cruel use for the Healing Touch: Using its BulletTime properties to kill people.
---> "Dr. Stiiiiiiiiiiiiiiles...do you know what else the "Healing" Touch is good for? It's also good for...[[http://i.imgur.com/O45mKVX.png KILLING]]!"
* In earlier operations, if you fail an operation, another doctor will simply take over for you, securing the patient's life. However, in later operations, whoever you're playing as is often the only doctor capable of dealing with whatever is inside the patient, which means if your patient's vitals hit 0 (or you [[TimedMission run out of time]]), your patient will outright '''die.'''
** In ''Under the Knife 2''[='=]s final operation, part of the BigBadDuumvirate has rigged the room to [[TakingYouWithMe infect everyone inside with Neo-GUILT if she dies]]. Oh, and she has to be operated on, because she is infected with [[FinalExamBoss Aletheia]] which the other half of said duumvirate has unwittingly activated. ''And'' the operation has several ways of knocking out a large fraction of her vitals or outright killing her if you make certain mistakes. Good luck.
** Aletheia itself is rather creepy, manifesting as a [[VideoGame/{{Kirby}} Dark Matter]]-esque [[EyesDoNotBelongThere eye]] on the patient's heart, which has turned lavender from Aletheia's mess enveloping it.
* The final Episode of ''Under the Knife'' (not ''Second Opinion'') reveals that GUILT is cultivated inside seven different children, all of which are labeled as "Sinners". In ''Under the Knife 2'', we find out that such biological atrocities run in the family: Heinrich does the same with his own children.

to:

* Trauma Team has a pretty scary one in terms of the main threat, which almost puts GUILT and Stigma to shame. The Rosalia Virus causes WAY too many people to die. And when Rosalia is in its active state, they bleed to DEATH through anything with a hole, including their EYES. Sandra Lieberman (The Raging Bomber) demonstrates this as the game gives the player a good close-up of her face as she succumbs to the disease before dying in an explosion.
** Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period. While giving you a touch of AxCrazy provided it spreads to the brain. It also just happens to leave its trademark black bruises in the shape of a freaking CLAW on the organs of most victims, most evidently on the liver, as the virus spreads across the body.
** It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant caterpillar in her ''heart''. The implications that it's the result of Rosalia and the remnants of GUILT mixing together only make it more disturbing.
** The most startling thing about Rosalia? It's not some artificial parasite or bioweapon designed for mass-murder. It's just a regular virus whose existence was not by the hands of madmen but by the random evolutions of nature. It manages to be ''even more dangerous'' and complicated to treat than GUILT and Stigma.
* In Under the Knife 2, Neo-GUILT (particularly Sige) also causes its victims to become AxCrazy.
** Call it {{Narm}} if you must, but Sige-infected Adel demonstrates a rather cruel use for the Healing Touch: Using its BulletTime properties to kill people.
---> "Dr. Stiiiiiiiiiiiiiiles...do you know what else the "Healing" Touch is good for? It's also good for...[[http://i.imgur.com/O45mKVX.png KILLING]]!"
* In earlier operations, if you fail an operation, another doctor will simply take over for you, securing the patient's life. However, in later operations, whoever you're playing as is often the only doctor capable of dealing with whatever is inside the patient, which means if your patient's vitals hit 0 (or you [[TimedMission run out of time]]), your patient will outright '''die.'''
** In ''Under the Knife 2''[='=]s final operation, part of the BigBadDuumvirate has rigged the room to [[TakingYouWithMe infect everyone inside with Neo-GUILT if she dies]]. Oh, and she has to be operated on, because she is infected with [[FinalExamBoss Aletheia]] which the other half of said duumvirate has unwittingly activated. ''And'' the operation has several ways of knocking out a large fraction of her vitals or outright killing her if you make certain mistakes. Good luck.
** Aletheia itself is rather creepy, manifesting as a [[VideoGame/{{Kirby}} Dark Matter]]-esque [[EyesDoNotBelongThere eye]] on the patient's heart, which has turned lavender from Aletheia's mess enveloping it.
* The final Episode of ''Under the Knife'' (not ''Second Opinion'') reveals that GUILT is cultivated inside seven different children, all of which are labeled as "Sinners". In ''Under the Knife 2'', we find out that such biological atrocities run in the family: Heinrich does the same with his own children.



** In ''Under the Knife 2'' while Angie and Derek were kidnapped by Delphi, Heinrich openly boast about his plans to use Angie to cultivate a new strain of GUILT, and use Derek as it's first test subject as a punishment for Blackwell's 'betrayal', and the duo for foiling the organisation's plans time and again. Now you know the consequences of what will happen to the two protagonists should you fail the 'surgery' to disable the lock to cell they were held in...
* In Trauma Team, Tomoe's mission ''Resolution'' is rather creepy: you guide her endoscope through a shifting maze of collapsed rubble with only the desperate cries for help from those trapped within to guide you. The appearance of some of the victims you can find are pretty jarring and are somewhat of a JumpScare since they're in 3D, in which you can see their full face and hands. Pretty frickin' unsettling.
* Another one in Trauma Team, at the end of one of Naomi's missions a bomb (inside a teddy bear) that is supposed to kill Naomi is taken by Alyssa and EXPLODES WHILE SHE'S HOLDING IT. Even though it was supposed to kill Naomi, it killed Alyssa's parents and almost killed Alyssa herself, leaving her orphaned. So in a really bad way, the [[TheBadGuyWins Raging Bomber still wins]], by killing even more people then she wanted. Although it makes it more satisfying once you finally catch her and she soon meets a somewhat similar fate [[HoistByHisOwnPetard by her own weapon]].
** Not only that, but the bombings examined by Naomi had the bombs explode at practically point-blank range. The third and fourth victims never had a chance to see their deaths coming.
* The ending of Naomi's second level in Trauma Team: Veronica suffers a seizure while she is locked in her room. She desperately calls for help, clawing her hands at the door until they bleed, which the game shows in gory detail. Her calls are unanswered, and she dies in horrible agony.
** The ''reason'' she was locked in her room - her condition caused her to go into violent fits that resulted in her ''permanently injuring her mother's vision''. There are no heroes or villains in this case, just desperate people with no real answers.
* Imagine being a perfectly normal, friendly and law-abiding person until one day you unknowingly become infected with a disease that causes damage to your brain that turns you into a violent, delusional psychopath. That's the root cause behind all but one of Naomi's cases -- completely normal people going insane as a result of an infection. And it can happen in real life too, particularly if one develops a brain tumor.
* The villain of ''New Blood'' reveals after you defeat the final operation that he's suffering from diencephalic sclerosis, which he was using Stigma to counteract. Translated from medical jargon, that means that ''his brain is petrifying''. That's a horrible thing to imagine, though it does explain why he dies so quickly after Stigma is removed.
* At the end of the FinalBoss of ''New Blood'', if all 20 of the Final Desperation tumors explode, it takes 750 off the vitals. It literally kills the patient '''[[TheresNoKillLikeOverkill seven and a half times.]]'''
* The [[BrutalBonusLevel X missions]] in Under the Knife 1, 2, and Second Opinion not only took all the [[NintendoHard already complicated and stressful]] [[BossBattle GUILT/Neo-GUILT surgeries]] [[UpToEleven up to an entirely new level in terms of difficulty]]. You will be performing them without the by now familiar and perhaps comforting assistance of Angie or any other ally by your side, with only the BigBad taunting you the entire time in the background on futility of your struggle against them. The feeling of isolation can be quite chilling to some.

to:

** In ''Under the Knife 2'' while Angie and Derek were kidnapped by Delphi, Heinrich openly boast about his plans to use Angie to cultivate a new strain of GUILT, and use Derek as it's first test subject as a punishment for Blackwell's 'betrayal', and the duo for foiling the organisation's plans time and again. Now you know the consequences of what will happen to the two protagonists should you fail the 'surgery' to disable the lock to cell they were held in...
* In Trauma Team, Tomoe's mission ''Resolution'' is rather creepy: you guide her endoscope through a shifting maze of collapsed rubble with only the desperate cries for help from those trapped within to guide you. The appearance of some of the victims you can find are pretty jarring and are somewhat of a JumpScare since they're in 3D, in which you can see their full face and hands. Pretty frickin' unsettling.
* Another one in Trauma Team, at the end of one of Naomi's missions a bomb (inside a teddy bear) that is supposed to kill Naomi is taken by Alyssa and EXPLODES WHILE SHE'S HOLDING IT. Even though it was supposed to kill Naomi, it killed Alyssa's parents and almost killed Alyssa herself, leaving her orphaned. So in a really bad way, the [[TheBadGuyWins Raging Bomber still wins]], by killing even more people then she wanted. Although it makes it more satisfying once you finally catch her and she soon meets a somewhat similar fate [[HoistByHisOwnPetard by her own weapon]].
** Not only that, but the bombings examined by Naomi had the bombs explode at practically point-blank range. The third and fourth victims never had a chance to see their deaths coming.
* The ending of Naomi's second level in Trauma Team: Veronica suffers a seizure while she is locked in her room. She desperately calls for help, clawing her hands at the door until they bleed, which the game shows in gory detail. Her calls are unanswered, and she dies in horrible agony.
** The ''reason'' she was locked in her room - her condition caused her to go into violent fits that resulted in her ''permanently injuring her mother's vision''. There are no heroes or villains in this case, just desperate people with no real answers.
* Imagine being a perfectly normal, friendly and law-abiding person until one day you unknowingly become infected with a disease that causes damage to your brain that turns you into a violent, delusional psychopath. That's the root cause behind all but one of Naomi's cases -- completely normal people going insane as a result of an infection. And it can happen in real life too, particularly if one develops a brain tumor.
! New Blood
* The villain of ''New Blood'' reveals after you defeat the final operation that he's suffering from diencephalic sclerosis, which he was using Stigma to counteract. Translated from medical jargon, that means that ''his brain is petrifying''. That's a horrible thing to imagine, though it does explain why he dies so quickly after Stigma is removed.
* At the end of the FinalBoss of ''New Blood'', FinalBoss, if all 20 of the Final Desperation tumors explode, it takes 750 off the vitals. It literally kills the patient '''[[TheresNoKillLikeOverkill seven and a half times.]]'''
* The [[BrutalBonusLevel X missions]] in ! Under the Knife 1, 2
* In Under the Knife
2, Neo-GUILT (particularly Sige) causes its victims to become AxCrazy.
** Call it {{Narm}} if you must, but Sige-infected Adel demonstrates a rather cruel use for the Healing Touch: Using its BulletTime properties to kill people.
---> "Dr. Stiiiiiiiiiiiiiiles...do you know what else the "Healing" Touch is good for? It's also good for...[[http://i.imgur.com/O45mKVX.png KILLING]]!"
* In the final operation, part of the BigBadDuumvirate has rigged the room to [[TakingYouWithMe infect everyone inside with Neo-GUILT if she dies]]. Oh,
and Second Opinion not only took all she has to be operated on, because she is infected with [[FinalExamBoss Aletheia]] which the [[NintendoHard already complicated and stressful]] [[BossBattle GUILT/Neo-GUILT surgeries]] [[UpToEleven up to an entirely new level in terms of difficulty]]. You will be performing them without the by now familiar and perhaps comforting assistance of Angie or any other ally by your side, with only half of said duumvirate has unwittingly activated. ''And'' the BigBad taunting operation has several ways of knocking out a large fraction of her vitals or outright killing her if you make certain mistakes. Good luck.
** Aletheia itself is rather creepy, manifesting as a [[VideoGame/{{Kirby}} Dark Matter]]-esque [[EyesDoNotBelongThere eye]] on
the entire time patient's heart, which has turned lavender from Aletheia's mess enveloping it.
* Remember
in the background on futility previous ''Under the Knife'', the virus was cultivated within children? We find out that such biological atrocities run in the family: Heinrich does the same with his own children.
** While Angie and Derek were kidnapped by Delphi, Heinrich openly boast about his plans to use Angie to cultivate a new strain
of your struggle against them. The feeling GUILT, and use Derek as it's first test subject as a punishment for Blackwell's 'betrayal', and the duo for foiling the organisation's plans time and again. Now you know the consequences of isolation can be quite chilling what will happen to some. the two protagonists should you fail the 'surgery' to disable the lock to cell they were held in...


Added DiffLines:

! Trauma Team
* This game has a pretty scary one in terms of the main threat, which almost puts GUILT and Stigma to shame. The Rosalia Virus causes WAY too many people to die. And when Rosalia is in its active state, they bleed to DEATH through anything with a hole, including their EYES. Sandra Lieberman (The Raging Bomber) demonstrates this as the game gives the player a good close-up of her face as she succumbs to the disease before dying in an explosion.
** Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period. While giving you a touch of AxCrazy provided it spreads to the brain. It also just happens to leave its trademark black bruises in the shape of a freaking CLAW on the organs of most victims, most evidently on the liver, as the virus spreads across the body.
** It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant caterpillar in her ''heart''. The implications that it's the result of Rosalia and the remnants of GUILT mixing together only make it more disturbing.
** The most startling thing about Rosalia? It's not some artificial parasite or bioweapon designed for mass-murder. It's just a regular virus whose existence was not by the hands of madmen but by the random evolutions of nature. It manages to be ''even more dangerous'' and complicated to treat than GUILT and Stigma.
* Tomoe's mission ''Resolution'' is rather creepy: you guide her endoscope through a shifting maze of collapsed rubble with only the desperate cries for help from those trapped within to guide you. The appearance of some of the victims you can find are pretty jarring and are somewhat of a JumpScare since they're in 3D, in which you can see their full face and hands. Pretty frickin' unsettling.
* Imagine being a perfectly normal, friendly and law-abiding person until one day you unknowingly become infected with a disease that causes damage to your brain that turns you into a violent, delusional psychopath. That's the root cause behind all but one of Naomi's cases -- completely normal people going insane as a result of an infection. And it can happen in real life too, particularly if one develops a brain tumor.
* The ending of Naomi's second level: Veronica suffers a seizure while she is locked in her room. She desperately calls for help, clawing her hands at the door until they bleed, which the game shows in gory detail. Her calls are unanswered, and she dies in horrible agony.
** The ''reason'' she was locked in her room - her condition caused her to go into violent fits that resulted in her ''permanently injuring her mother's vision''. There are no heroes or villains in this case, just desperate people with no real answers.
* At the end of one of Naomi's missions a bomb (inside a teddy bear) that is supposed to kill Naomi is taken by Alyssa and EXPLODES WHILE SHE'S HOLDING IT. Even though it was supposed to kill Naomi, it killed Alyssa's parents and almost killed Alyssa herself, leaving her orphaned. So in a really bad way, the [[TheBadGuyWins Raging Bomber still wins]], by killing even more people then she wanted. Although it makes it more satisfying once you finally catch her and she soon meets a somewhat similar fate [[HoistByHisOwnPetard by her own weapon]].
** Not only that, but the bombings examined by Naomi had the bombs explode at practically point-blank range. The third and fourth victims never had a chance to see their deaths coming.
Is there an issue? Send a MessageReason:
None


* Linda Reid, a patient with suicidal tendencies, can hit a little too close to home for those who have attempted suicide or have a close friend who has. Luckily, Stiles patches up her wounds, and gives her a talk that manages to give her new perspective on life, and she gives up on her suicidal tendencies. [[WhamEpisode Then her wounds re-open on their own, and we get our first encounter with GUILT and its effects]]. Also, just consider: [[FridgeHorror how long were those strains of Kyriaki inside her, cutting her up from the inside]]?

to:

* Linda Reid, a patient with suicidal tendencies, can hit a little too close to home for those who have attempted suicide or have a close friend who has. Luckily, Stiles patches up her wounds, and gives her a talk that manages to give her new perspective on life, and she gives up on her suicidal tendencies. [[WhamEpisode Then her wounds re-open on their own, own before your very eyes, and we get our first encounter with GUILT and its effects]]. Also, just consider: [[FridgeHorror how long were those strains of Kyriaki inside her, cutting her up from the inside]]?
Is there an issue? Send a MessageReason:
None

Added DiffLines:

* Imagine being a perfectly normal, friendly and law-abiding person until one day you unknowingly become infected with a disease that causes damage to your brain that turns you into a violent, delusional psychopath. That's the root cause behind all but one of Naomi's cases -- completely normal people going insane as a result of an infection. And it can happen in real life too, particularly if one develops a brain tumor.

Added: 465

Changed: 743

Is there an issue? Send a MessageReason:
None


* In ''Under The Knife'' and ''Second Opinion'', there is one operation where your "patient" is a ''time bomb''. Fail to defuse it in time, or [[ParanoiaFuel mess up on certain tasks]], and to nobody's surprise, Derek gets a front-row seat of the bomb's explosion.

to:

* In ''Under The Knife'' and ''Second Opinion'', there is one operation where your "patient" is a ''time bomb''. Fail to defuse it in time, or [[ParanoiaFuel mess fail to keep up on certain tasks]], with its triggering mechanisms/make too many mistakes]], and to nobody's surprise, Derek gets a front-row seat of the bomb's explosion.



** Savato is essentially an ''acidic spider'' that neutralizes its victim's heartbeat and drains the energy spent by the heart to sustain itself. And when it's close to defeat, it goes ''absolutely berserk'' and needs [[TimeStandsStill the double Healing Touch]] to stop it from tearing the heart to shreds.



* Trauma Team has a pretty scary one in terms of the main threat, which almost puts GUILT and Stigma to shame. The Rosalia Virus causes WAY too many people to die. And when a person truly dies, they bleed to DEATH through anything with a hole, including their EYES. Sandra Lieberman (The Raging Bomber) demonstrates this as the game gives the player a good close-up of her face as she succumbs to the disease before dying in an explosion.
** Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period. While giving you a touch of AxCrazy provided it spreads to the brain. It also just happens to leave its trademark black bruises in the shape of a freaking CLAW on the liver of most victims. It's likely a consequence of the bruises forming near the entry point of the liver but it still looks frightening.
** It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant worm in her ''heart''. The implications that it's the result of Rosalia and the remnants of GUILT mixing together only make it more disturbing.
* By Under the Knife 2, Neo GUILT also causes Ax Craziness.
** Call it {{Narm}} if you must, but Neo-GUILT-infected Adel demonstrates a rather cruel use for the Healing Touch: Using its BulletTime properties to kill people.

to:

* Trauma Team has a pretty scary one in terms of the main threat, which almost puts GUILT and Stigma to shame. The Rosalia Virus causes WAY too many people to die. And when a person truly dies, Rosalia is in its active state, they bleed to DEATH through anything with a hole, including their EYES. Sandra Lieberman (The Raging Bomber) demonstrates this as the game gives the player a good close-up of her face as she succumbs to the disease before dying in an explosion.
** Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period. While giving you a touch of AxCrazy provided it spreads to the brain. It also just happens to leave its trademark black bruises in the shape of a freaking CLAW on the liver organs of most victims. It's likely a consequence of victims, most evidently on the bruises forming near liver, as the entry point of virus spreads across the liver but it still looks frightening.
body.
** It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant worm caterpillar in her ''heart''. The implications that it's the result of Rosalia and the remnants of GUILT mixing together only make it more disturbing.
** The most startling thing about Rosalia? It's not some artificial parasite or bioweapon designed for mass-murder. It's just a regular virus whose existence was not by the hands of madmen but by the random evolutions of nature. It manages to be ''even more dangerous'' and complicated to treat than GUILT and Stigma.
* By In Under the Knife 2, Neo GUILT Neo-GUILT (particularly Sige) also causes Ax Craziness.
its victims to become AxCrazy.
** Call it {{Narm}} if you must, but Neo-GUILT-infected Sige-infected Adel demonstrates a rather cruel use for the Healing Touch: Using its BulletTime properties to kill people.

Added: 210

Changed: 85

Is there an issue? Send a MessageReason:
None


** In ''Under the Knife 2''[='=]s final operation, the BigBad has rigged the room to [[TakingYouWithMe infect everyone inside with Neo-GUILT if she dies]]. Oh, and she has to be operated on, because she is infected with [[FinalExamBoss Aletheia]]. ''And'' the operation has several ways of knocking out a large fraction of her vitals or outright killing her if you make certain mistakes. Good luck.

to:

** In ''Under the Knife 2''[='=]s final operation, part of the BigBad BigBadDuumvirate has rigged the room to [[TakingYouWithMe infect everyone inside with Neo-GUILT if she dies]]. Oh, and she has to be operated on, because she is infected with [[FinalExamBoss Aletheia]].Aletheia]] which the other half of said duumvirate has unwittingly activated. ''And'' the operation has several ways of knocking out a large fraction of her vitals or outright killing her if you make certain mistakes. Good luck.luck.
** Aletheia itself is rather creepy, manifesting as a [[VideoGame/{{Kirby}} Dark Matter]]-esque [[EyesDoNotBelongThere eye]] on the patient's heart, which has turned lavender from Aletheia's mess enveloping it.



* At the end of the FinalBoss of ''New Blood'', if all 20 of the Final Desperation tumors explode, it takes 750 off the vitals. It literally kills the patient '''[[TheresNoKillLikeOverkill seven and a half times.]]'''

to:

* At the end of the FinalBoss of ''New Blood'', if all 20 of the Final Desperation tumors explode, it takes 750 off the vitals. It literally kills the patient '''[[TheresNoKillLikeOverkill seven and a half times.]]''']]'''
Is there an issue? Send a MessageReason:
None

Added DiffLines:

** The ''reason'' she was locked in her room - her condition caused her to go into violent fits that resulted in her ''permanently injuring her mother's vision''. There are no heroes or villains in this case, just desperate people with no real answers.
Is there an issue? Send a MessageReason:
None


* In ''Under The Knife'' and ''Second Opinion'', there is one operation where your "patient" is a ''time bomb''. Fail to defuse it in time, or [[ParanoiaFuel mess up on certain precision-demanding tasks]], and to nobody's surprise, Derek gets a front-row seat of the bomb's explosion.

to:

* In ''Under The Knife'' and ''Second Opinion'', there is one operation where your "patient" is a ''time bomb''. Fail to defuse it in time, or [[ParanoiaFuel mess up on certain precision-demanding tasks]], and to nobody's surprise, Derek gets a front-row seat of the bomb's explosion.
Is there an issue? Send a MessageReason:
None

Added DiffLines:

* In ''Under The Knife'' and ''Second Opinion'', there is one operation where your "patient" is a ''time bomb''. Fail to defuse it in time, or [[ParanoiaFuel mess up on certain precision-demanding tasks]], and to nobody's surprise, Derek gets a front-row seat of the bomb's explosion.
Is there an issue? Send a MessageReason:
None


** Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period. While giving you a touch of AxCrazy provided it spreads to the brain. It also just happens to leave it's trademark black bruises in the shape of a freaking CLAW on the liver of most victims. It's likely a consequence of the bruises forming near the entry point of the liver but it still looks frightening.

to:

** Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period. While giving you a touch of AxCrazy provided it spreads to the brain. It also just happens to leave it's its trademark black bruises in the shape of a freaking CLAW on the liver of most victims. It's likely a consequence of the bruises forming near the entry point of the liver but it still looks frightening.
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[[caption-width-right:350:This is in the ''first'' chapter, by the way. You get even worse operations later.]]

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[[caption-width-right:350:This is in the ''first'' ''[[EstablishingSeriesMoment first]]'' chapter, by the way. You get even worse operations later.]]



* At first, the operations in ''Under the Knife'' / ''[[VideoGameRemake Second Opinion]]'' are relatively low-tension operations: removing glass from a patient's arm, removing tumors from another patient's stomach, burning away polyps from someone's throat. Might make some players queasy, but nothing really life-threatening happening. However, the operation at the end of the first chapter is a WhamEpisode, giving you the first life-or-death operation in the game. Defibrillator, done. Remove glass shards from patient's chest area, done. Open up patient and oh god there are shards of glass in his heart too!

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* At first, the operations in ''Under the Knife'' / ''[[VideoGameRemake Second Opinion]]'' are relatively low-tension operations: removing glass from a patient's arm, removing tumors from another patient's stomach, burning away polyps from someone's throat. Might make some players queasy, but nothing really life-threatening happening. However, the operation at [[EstablishingSeriesMoment the end of the first chapter chapter]] is a WhamEpisode, giving you the first life-or-death operation in the game. Defibrillator, done. Remove glass shards from patient's chest area, done. Open up patient and oh god there are shards of glass in his heart too!
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** In ''Under the Knife 2''[='=]s final operation, [[spoiler:the BigBad has rigged the room to [[TakingYouWithMe infect everyone inside with Neo-GUILT if she dies]]. Oh, and she has to be operated on, because she is infected with [[FinalExamBoss Aletheia]]. ''And'' the operation has several ways of knocking out a large fraction of her vitals or outright killing her if you make certain mistakes. Good luck.]]

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** In ''Under the Knife 2''[='=]s final operation, [[spoiler:the the BigBad has rigged the room to [[TakingYouWithMe infect everyone inside with Neo-GUILT if she dies]]. Oh, and she has to be operated on, because she is infected with [[FinalExamBoss Aletheia]]. ''And'' the operation has several ways of knocking out a large fraction of her vitals or outright killing her if you make certain mistakes. Good luck.]]



** Imagine being in the shoes of a parent who discovers their child is a suitable subject for this nefarious purpose. [[spoiler:No wonder why Blackwell joined Delphi to save his daughter.]]
** Conversely, imagine being in [[spoiler:Angie]]'s shoes, having to live with the knowledge that the only reason you were spared from this atrocity is that [[spoiler:your own father helped to inflict that very same atrocity on several other children]].

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** Imagine being in the shoes of a parent who discovers their child is a suitable subject for this nefarious purpose. [[spoiler:No No wonder why Blackwell joined Delphi to save his daughter.]]
daughter.
** Conversely, imagine being in [[spoiler:Angie]]'s Angie's shoes, having to live with the knowledge that the only reason you were spared from this atrocity is that [[spoiler:your your own father helped to inflict that very same atrocity on several other children]].children.



* Another one in Trauma Team, at the end of one of Naomi's missions [[spoiler:a bomb (inside a teddy bear) that is supposed to kill Naomi is taken by Alyssa and EXPLODES WHILE SHE'S HOLDING IT. Even though it was supposed to kill Naomi, it killed Alyssa's parents and almost killed Alyssa herself, leaving her orphaned. So in a really bad way, the [[TheBadGuyWins Raging Bomber still wins]], by killing even more people then she wanted. Although it makes it more satisfying once you finally catch her and she soon meets a somewhat similar fate [[HoistByHisOwnPetard by her own weapon]].]]

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* Another one in Trauma Team, at the end of one of Naomi's missions [[spoiler:a a bomb (inside a teddy bear) that is supposed to kill Naomi is taken by Alyssa and EXPLODES WHILE SHE'S HOLDING IT. Even though it was supposed to kill Naomi, it killed Alyssa's parents and almost killed Alyssa herself, leaving her orphaned. So in a really bad way, the [[TheBadGuyWins Raging Bomber still wins]], by killing even more people then she wanted. Although it makes it more satisfying once you finally catch her and she soon meets a somewhat similar fate [[HoistByHisOwnPetard by her own weapon]].]]
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* Trauma Team has a pretty scary one in terms of the main threat, which almost puts GUILT and Stigma to shame. [[spoiler:The Rosalia Virus causes WAY too many people to die. And when a person truly dies, they bleed to DEATH through anything with a hole, including their EYES. Sandra Lieberman (The Raging Bomber) demonstrates this as the game gives the player a good close-up of her face as she succumbs to the disease before dying in an explosion.]]
** [[spoiler:Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period.]] While giving you a [[spoiler: touch of AxCrazy provided it spreads to the brain. It also just happens to leave it's trademark black bruises in the shape of a freaking CLAW on the liver of most victims. It's likely a consequence of the bruises forming near the entry point of the liver but it still looks frighting.]]
** [[spoiler: It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant worm in her ''heart''. The implications that it's the result of Rosalia and the remnants of GUILT mixing together only make it more disturbing.]]

to:

* Trauma Team has a pretty scary one in terms of the main threat, which almost puts GUILT and Stigma to shame. [[spoiler:The The Rosalia Virus causes WAY too many people to die. And when a person truly dies, they bleed to DEATH through anything with a hole, including their EYES. Sandra Lieberman (The Raging Bomber) demonstrates this as the game gives the player a good close-up of her face as she succumbs to the disease before dying in an explosion.]]
explosion.
** [[spoiler:Rosalia Rosalia is filoviridae (Ebola-type virus) that is spread by butterflies, or more accurately, the wing scales they shed during their migration period.]] period. While giving you a [[spoiler: touch of AxCrazy provided it spreads to the brain. It also just happens to leave it's trademark black bruises in the shape of a freaking CLAW on the liver of most victims. It's likely a consequence of the bruises forming near the entry point of the liver but it still looks frighting.]]
frightening.
** [[spoiler: It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant worm in her ''heart''. The implications that it's the result of Rosalia and the remnants of GUILT mixing together only make it more disturbing.]]



** Call it {{Narm}} if you must, but [[spoiler:Neo-GUILT-infected Adel demonstrates a rather cruel use for the Healing Touch: Using its BulletTime properties to kill people.]]

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** Call it {{Narm}} if you must, but [[spoiler:Neo-GUILT-infected Neo-GUILT-infected Adel demonstrates a rather cruel use for the Healing Touch: Using its BulletTime properties to kill people.]]



* The final Episode of ''Under the Knife'' (not ''Second Opinion'') reveals that GUILT is cultivated inside [[spoiler:seven different children, all of which are labeled as "Sinners".]] In ''Under the Knife 2'', we find out that such biological atrocities [[spoiler:run in the family: Heinrich does the same with his own children.]]

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* The final Episode of ''Under the Knife'' (not ''Second Opinion'') reveals that GUILT is cultivated inside [[spoiler:seven seven different children, all of which are labeled as "Sinners".]] "Sinners". In ''Under the Knife 2'', we find out that such biological atrocities [[spoiler:run run in the family: Heinrich does the same with his own children.]]



** Not only that, but the [[spoiler:bombings examined by Naomi had the bombs explode at practically point-blank range. The third and fourth victims never had a chance to see their deaths coming]].
* The ending of Naomi's second level in Trauma Team: [[spoiler: Veronica suffers a seizure while she is locked in her room. She desperately calls for help, clawing her hands at the door until they bleed, which the game shows in gory detail. Her calls are unanswered, and she dies in horrible agony]].
* The villain of ''New Blood'' reveals after you defeat the final operation that [[spoiler:he's suffering from diencephalic sclerosis, which he was using Stigma to counteract]]. Translated from medical jargon, that means that [[spoiler:''his brain is petrifying'']]. That's a horrible thing to imagine, though it does explain [[spoiler:why he dies so quickly after Stigma is removed]].

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** Not only that, but the [[spoiler:bombings bombings examined by Naomi had the bombs explode at practically point-blank range. The third and fourth victims never had a chance to see their deaths coming]].
coming.
* The ending of Naomi's second level in Trauma Team: [[spoiler: Veronica suffers a seizure while she is locked in her room. She desperately calls for help, clawing her hands at the door until they bleed, which the game shows in gory detail. Her calls are unanswered, and she dies in horrible agony]].
agony.
* The villain of ''New Blood'' reveals after you defeat the final operation that [[spoiler:he's he's suffering from diencephalic sclerosis, which he was using Stigma to counteract]]. counteract. Translated from medical jargon, that means that [[spoiler:''his ''his brain is petrifying'']]. petrifying''. That's a horrible thing to imagine, though it does explain [[spoiler:why why he dies so quickly after Stigma is removed]].removed.
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---> ''''Chapter 6-4, 6-6'''': Six months passed after the abduction of Derek Stiles and Angie Thompson. All leads were exhausted; no one even knew if they were alive or dead. The battle against Delphi's bioterrorism worsened day by day... And before long, Derek and Angie faded from memory.
---> ''''Chapter 7-5, 7-6, 7-7'''': The mission to contain the threat posed by Neo-GUILT ended in failure; modern medicine was powerless against what was beyond human understanding. Derek Stiles was never found, and his illustrious reputation faded into obscurity. To this day, it is uncertain whether or not humanity was freed from the cursed legacy of GUILT.

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---> ''''Chapter -->'''Chapter 6-4, 6-6'''': 6-6''': Six months passed after the abduction of Derek Stiles and Angie Thompson. All leads were exhausted; no one even knew if they were alive or dead. The battle against Delphi's bioterrorism worsened day by day... And before long, Derek and Angie faded from memory.
---> ''''Chapter -->'''Chapter 7-5, 7-6, 7-7'''': 7-7''': The mission to contain the threat posed by Neo-GUILT ended in failure; modern medicine was powerless against what was beyond human understanding. Derek Stiles was never found, and his illustrious reputation faded into obscurity. To this day, it is uncertain whether or not humanity was freed from the cursed legacy of GUILT.
GUILT.
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* When they are not Tearjerker describing Derek abandoning medicine forever, the GameOver screen for ''Under the Knife 2'' can be quite the NightmareFuel implying the death of Derek and Angie at best, or a FateWorseThanDeath at worst.
---> ''''Chapter 6-4, 6-6'''': Six months passed after the abduction of Derek Stiles and Angie Thompson. All leads were exhausted; no one even knew if they were alive or dead. The battle against Delphi's bioterrorism worsened day by day... And before long, Derek and Angie faded from memory.
---> ''''Chapter 7-5, 7-6, 7-7'''': The mission to contain the threat posed by Neo-GUILT ended in failure; modern medicine was powerless against what was beyond human understanding. Derek Stiles was never found, and his illustrious reputation faded into obscurity. To this day, it is uncertain whether or not humanity was freed from the cursed legacy of GUILT.
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* The [[BrutalBonusLevel X missions]] in Under the Knife 1, 2, and Second Opinion not only took all the [[NintendoHard already complicated and stressful]] [[BossBattle GUILT/Neo-GUILT surgeries]][[UpToEleven up to an entirely new level in terms of difficulty]]. You will be performing them without the by now familiar and perhaps comforting assistance of Angie or any other ally by your side, with only the BigBad taunting you the entire time in the background on futility of your struggle against them. The feeling of isolation can be quite chilling to some.

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* The [[BrutalBonusLevel X missions]] in Under the Knife 1, 2, and Second Opinion not only took all the [[NintendoHard already complicated and stressful]] [[BossBattle GUILT/Neo-GUILT surgeries]][[UpToEleven surgeries]] [[UpToEleven up to an entirely new level in terms of difficulty]]. You will be performing them without the by now familiar and perhaps comforting assistance of Angie or any other ally by your side, with only the BigBad taunting you the entire time in the background on futility of your struggle against them. The feeling of isolation can be quite chilling to some.
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* The [[BrutalBonusLevel X missions]] in Under the Knife 1, 2, and Second Opinion not only took all the [[NintendoHard already complicated and stressful]] [[BossBattle GUILT/Neo-GUILT surgeries]][[UpToEleven up to an entirely new level in terms of difficulty]]. You will be performing them without the by now familiar and perhaps comforting assistance of Angie or any other ally by your side, with only the BigBad taunting you the entire time in the background on futility of your struggle against them. The feeling of isolation can be quite chilling to some.
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** In ''Under the Knife 2'' while Angie and Derek were kidnapped by Delphi, Heinrich openly boast about his plans to use Angie to cultivate a new strain of GUILT, and use Derek as it's first test subject as a punishment for Blackwell's 'betrayal', and the duo for foiling the organisation's plans time and again. Now you know the consequences of what will happen to the two protagonists should you fail the 'surgery' to disable the lock to cell they were held in...
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Dr. Stiiiiiiiiiiiles...do you know what else ''VideoGame/TraumaCenter'' is good for? It's also good for...'''[[NightmareFuel SCARING!]]'''

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Dr. Stiiiiiiiiiiiles... do you know what else ''VideoGame/TraumaCenter'' is good for? It's also good for...for... '''[[NightmareFuel SCARING!]]'''
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* At the end of the FinalBoss of ''New Blood'', if all 20 of the Final Desperation tumors explode, it takes 750 off the vitals. It literally kills the patient '''[[TheresNoKillLikeOverkill seven and a half times.]]'''
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** [[spoiler: It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant worm in her ''heart''.]]

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** [[spoiler: It gets worse when Naomi contracts it. Twisted Rosalia is essentially a giant worm in her ''heart''. The implications that it's the result of Rosalia and the remnants of GUILT mixing together only make it more disturbing.]]
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** Paraskevi in particular doesn't just try to damage the patient, it tries to burrow its way deeper and deeper, until it's at the victim's heart. If it goes inside ''that'', [[OneHitKill it's an immediate game over]].
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[[quoteright:350:http://static.tvtropes.org/pmwiki/pub/images/chrome_2018_01_07_00_17_57.png]]
[[caption-width-right:350:This is in the ''first'' chapter, by the way. You get even worse operations later.]]
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* The ending of Naomi's second level in Trauma Team: [[spoiler: Veronica suffers a seizure while she is locked in her room. She desperately calls for help, clawing her hands at the door until they bleed, which the game shows in gory detail. Her calls are unanswered, and she dies in horrible agony]].
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** Conversely, imagine being in [[spoiler:Angie]]'s shoes, having to live with the knowledge that the only reason you were spared from this atrocity is that [[spoiler:your own father helped to inflict that very same atrocity on several other children]].
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** At least GUILT and all its horror-inducing injuries are fictional, right? Turns out the various strains are inspired by other real-life deadly pathogens or diseases. They may not be as lethal as GUILT, but being subject to those diseases is not pleasant.


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** Imagine being in the shoes of a parent who discovers their child is a suitable subject for this nefarious purpose. [[spoiler:No wonder why Blackwell joined Delphi to save his daughter.]]
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** Most pathogens want to keep their host alive. Plagues usually are only so deadly because they've jumped species and do things that would be nothing too dangerous in their usual host, but very bad for their actual one. GUILT and Stigma don't observe this rule. As genetically engineered diseases, they do everything in their power to make sure their victim is dead as fast as possible. ''They don't care about their own survival.'' What's worse, when they sense that they're being threatened, they resolve to do ''as much damage as they possibly can,'' with the singular goal of killing the person they're in before they can be removed.

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** Most pathogens want to keep their host alive. Plagues [[ThePlague Plagues]] usually are only so deadly because they've jumped species and do things that would be nothing too dangerous in their usual host, but very bad for their actual one. GUILT and Stigma don't observe this rule. As [[SyntheticPlague genetically engineered diseases, diseases]], they do everything in their power to make sure their victim is dead as fast as possible. ''They don't care about their own survival.'' What's worse, when they sense that they're being threatened, they resolve to do ''as much damage as they possibly can,'' with the singular goal of killing the person they're in before they can be removed.

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