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* After ''Series/OneLifeToLive'''s Jessica is badly injured in a car accident, her surgeon informs her family that they had to remove her spleen, as it was ruptured. There's no mention of the fact that she'll be vulnerable to infection from now on.
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** In ''Literature/SpiderManTheVenomFactor'', ComicBook/{{Venom}} states that when he finds whoever is responsible for the murders (that Venom is being wrongly accused of) he will eat his spleen. Spider-Man comments that this is an odd choice of organ to target and that Venom likely doesn't even know where someone's spleen is.
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** In ''Literature/SpiderManTheVenomFactor'', ''Literature/SpiderManTheVenomTrilogy'', ComicBook/{{Venom}} states that when he finds whoever is responsible for the murders (that Venom is being wrongly accused of) he will eat his spleen. Spider-Man comments that this is an odd choice of organ to target and that Venom likely doesn't even know where someone's spleen is.
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** In the ''Literature/SinisterSixTrilogy'', Spider-Man casually jokes about Venom wanting to eat his spleen. He speculates that it's not specifically the spleen he's after, they both just think it's [[InherentlyFunnyWord a funny word]].
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** In the ''Literature/SinisterSixTrilogy'', ''Literature/SpiderManSinisterSixTrilogy'', Spider-Man casually jokes about Venom wanting to eat his spleen. He speculates that it's not specifically the spleen he's after, they both just think it's [[InherentlyFunnyWord a funny word]].
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** In the novel ''[[Literature/SpiderManTheVenomFactor The Venom Factor]]'', ComicBook/{{Venom}} states that when he finds whoever is responsible for the murders (that Venom is being wrongly accused of) he will eat his spleen. Spider-Man comments that this is an odd choice of organ to target and that Venom likely doesn't even know where someone's spleen is.
** Comes back in the ''Literature/SinisterSixTrilogy'' where Spider-Man casually jokes about Venom wanting to eat his spleen. He speculates that it's not specifically the spleen he's after, they both just think it's [[InherentlyFunnyWord a funny word]].
** Comes back in the ''Literature/SinisterSixTrilogy'' where Spider-Man casually jokes about Venom wanting to eat his spleen. He speculates that it's not specifically the spleen he's after, they both just think it's [[InherentlyFunnyWord a funny word]].
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** In the novel ''[[Literature/SpiderManTheVenomFactor The Venom Factor]]'', ''Literature/SpiderManTheVenomFactor'', ComicBook/{{Venom}} states that when he finds whoever is responsible for the murders (that Venom is being wrongly accused of) he will eat his spleen. Spider-Man comments that this is an odd choice of organ to target and that Venom likely doesn't even know where someone's spleen is.
**Comes back in In the ''Literature/SinisterSixTrilogy'' where ''Literature/SinisterSixTrilogy'', Spider-Man casually jokes about Venom wanting to eat his spleen. He speculates that it's not specifically the spleen he's after, they both just think it's [[InherentlyFunnyWord a funny word]].
**
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* ''Series/{{CSI}}'':
** A few [[BodyOfTheWeek Bodies of the Week]] from the franchise have succumbed to bleeding out after a bludgeoning attack or collision ruptured their spleen. An aversion of sorts, as it reminds viewers that, whether or not a working spleen is essential to survival, an ''injured'' spleen is liable to kill you in the absence of emergency surgery.
** The first subject of serial killer "Dr. Jekyll"'s surgical experiments was an already-deceased man whose small intestine had been tied in a bow around his spleen.
** A few [[BodyOfTheWeek Bodies of the Week]] from the franchise have succumbed to bleeding out after a bludgeoning attack or collision ruptured their spleen. An aversion of sorts, as it reminds viewers that, whether or not a working spleen is essential to survival, an ''injured'' spleen is liable to kill you in the absence of emergency surgery.
** The first subject of serial killer "Dr. Jekyll"'s surgical experiments was an already-deceased man whose small intestine had been tied in a bow around his spleen.
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** ''Series/{{CSI}}'': The first subject of serial killer "Dr. Jekyll"'s surgical experiments was an already-deceased man whose small intestine had been tied in a bow around his
** ''Series/{{CSINY}}'': Zig-zagged in "[[Recap/CSINYS05E05 The Cost of Living]]." While a deceased victim's medical records show that his spleen had been removed, M.E. Sid Hammerback finds a perfectly healthy one in his body. The discovery of the organ leads the team to the man's true identity... and eventually to his killer.
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* Getting hurt in the spleen is a sort of long-term RunningGag in ''WebComic/SluggyFreelance''. It's more than just mentioned in a parody of ''Film/KillBill'', in which [[HairRaisingHare Bun-bun]] is [[AcceptableTargets killing telemarketers]], and he's shown holding a spleen that he says one of them "dropped".
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* Getting hurt in the spleen is a sort of long-term RunningGag in ''WebComic/SluggyFreelance''. It's more than just mentioned in a parody of ''Film/KillBill'', in which [[HairRaisingHare Bun-bun]] is [[AcceptableTargets killing telemarketers]], telemarketers, and he's shown holding a spleen that he says one of them "dropped".
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* ''Series/MarriedWithChildren'': In a two-part episode, Bud borrowed money from a loan shark named [[NamesToRunAwayFromReallyFast Vito Capone]]. ("[[Film/TheGodfather No]] [[UsefulNotes/AlCapone relation]]", he says) When it seemed he'd not be able to repay, Vito said something about extracting Bud's spleen. When Bud asked he'd be able to live without a spleen, Vito said he could. (Not that it matter, since it'd not be the only organ he'd lose)
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* ''Series/MarriedWithChildren'': In a two-part episode, Bud borrowed money from a loan shark named [[NamesToRunAwayFromReallyFast Vito Capone]]. ("[[Film/TheGodfather No]] [[UsefulNotes/AlCapone relation]]", he says) When it seemed he'd not be able to repay, Vito said something about extracting Bud's spleen. When Bud asked he'd be able to live without a spleen, Vito said he could. (Not that it matter, since it'd not be the only organ he'd lose)lose.)
* ''Series/{{Newhart}}'': Michael has a fantasy/dream in which an older version of himself has a conversation with his infant daughter as an adult. He's sold his spleen (and one of his kidneys) in order to buy her the very last cashmere sweater to complete her collection, but now she wants shoes. He'd sell his blood to pay for them, but he's not sure he can even make new blood without a spleen.
* ''Series/{{Newhart}}'': Michael has a fantasy/dream in which an older version of himself has a conversation with his infant daughter as an adult. He's sold his spleen (and one of his kidneys) in order to buy her the very last cashmere sweater to complete her collection, but now she wants shoes. He'd sell his blood to pay for them, but he's not sure he can even make new blood without a spleen.
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* The WebAnimation/{{Animutation}} ''[[WebAnimation/ColinMochrieVsJesusHChrist French Erotic Film]]'' has a group of character parodying WesternAnimation/{{Captain Planet|AndThePlaneteers}} in order to stop [[Series/WhoseLineIsItAnyway Colin Mochrie]] who has turned into a crazy scotsman. But instead of summoning with the power of Heart, they use the power of Spleen, with a FreezeFrameBonus asking WhatKindOfLamePowerIsHeartAnyway.
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* The WebAnimation/{{Animutation}} {{Animutation}} ''[[WebAnimation/ColinMochrieVsJesusHChrist French Erotic Film]]'' has a group of character parodying WesternAnimation/{{Captain Planet|AndThePlaneteers}} in order to stop [[Series/WhoseLineIsItAnyway Colin Mochrie]] who has turned into a crazy scotsman. But instead of summoning with the power of Heart, they use the power of Spleen, with a FreezeFrameBonus asking WhatKindOfLamePowerIsHeartAnyway.
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* One of the [[VideoGame/Postal2 Postal Dude's]] injury reaction lines is: "Ow, my spleen's poking out!"
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** ''The Deadlock Protocol'' sees captured Solaris workers being held aboard Corpus ships to be sent into the Granum Void. One voiceline from a captured worker threatens to make the Corpus workers know the taste of their own spleen.
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* A throwaway gag of ''Machinima/RedVsBlue'' has Grif grievously injured and in immediate need of surgery. Simmons [[GotVolunteered "volunteers"]] to donate his organs to Grif, becoming a {{Cyborg}} in the process. Almost every organ is transplanted, except for the spleen, [[{{Squick}} which is inflated and used for general recreation, and espirits de corps.]]
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* A throwaway gag of ''Machinima/RedVsBlue'' ''WebAnimation/RedVsBlue'' has Grif grievously injured and in immediate need of surgery. Simmons [[GotVolunteered "volunteers"]] to donate his organs to Grif, becoming a {{Cyborg}} in the process. Almost every organ is transplanted, except for the spleen, [[{{Squick}} which is inflated and used for general recreation, and espirits de corps.]]
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* Invoked by ''LetsPlay/GrayStillPlays''. "Spleens" is what he named his derpy-looking, {{Cloudcuckoolander}} virtual cat that serves as a RecurringCharacter (and even kind of a {{mascot}} for Gray) in his ''VideoGame/TheSims4'' videos.
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* Invoked by ''LetsPlay/GrayStillPlays''.''WebVideo/GrayStillPlays''. "Spleens" is what he named his derpy-looking, {{Cloudcuckoolander}} virtual cat that serves as a RecurringCharacter (and even kind of a {{mascot}} for Gray) in his ''VideoGame/TheSims4'' videos.
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* ''ComicBook/RobinSeries'': Tim Drake loses his spleen to a sword-strike in ''Red Robin #4''.
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* ''ComicBook/RobinSeries'': ''ComicBook/RedRobin'': Tim Drake loses his spleen to a sword-strike in ''Red Robin #4''.the fourth issue.
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* ''VideoGame/{{Warframe}}'': A Kuva Lich with the "Jovial" personality has two lines involving his spleen:
-->'''Lich''' : (upon being hit with a correct Requiem Mod combination) Ugh, I can ''taste'' my spleen... that's not good.
-->'''Lich''': (when downed as an ally) Ouch! Got me right in the roto-spleen.
-->'''Lich''' : (upon being hit with a correct Requiem Mod combination) Ugh, I can ''taste'' my spleen... that's not good.
-->'''Lich''': (when downed as an ally) Ouch! Got me right in the roto-spleen.
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* Rikku in ''VideoGame/FinalFantasyX2'' has the in-battle quote: "Imma kick you in the spleen!", to which Paine replies "...Spleen?"
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* Rikku [[GenkiGirl Rikku]] in ''VideoGame/FinalFantasyX2'' has the in-battle quote: "Imma kick you in the spleen!", to which Paine [[TheComicallySerious Paine]] replies "...Spleen?"
