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* In ''VideoGame/DigitalDevilSaga'', everyone infected by the demon virus has access to demon form, which is stronger than human form. Said demon form ranges from looking vaguely humanoid (most of the main characters), to slimes, to animalistic, to the [[EldritchAbomination worst looking of]] ''Franchise/ShinMegamiTensei'' [[EldritchAbomination demons]].
** In the main ''Franchise/ShinMegamiTensei'' series, human-demon fusion is quite likely to leave you like this, in ''IV'', some of the poor bastards who chose to become Demonoids were hit with ''Fusion Errors''. If you're not careful with Reds, in the same game, you will end up as a shambling undead. Or worse.
** In the main ''Franchise/ShinMegamiTensei'' series, human-demon fusion is quite likely to leave you like this, in ''IV'', some of the poor bastards who chose to become Demonoids were hit with ''Fusion Errors''. If you're not careful with Reds, in the same game, you will end up as a shambling undead. Or worse.
to:
* In ''VideoGame/DigitalDevilSaga'', everyone infected by the demon virus has access to demon form, which is stronger than human form. Said demon form ranges from looking vaguely humanoid (most of the main characters), to slimes, to animalistic, to the [[EldritchAbomination worst looking of]] ''Franchise/ShinMegamiTensei'' [[EldritchAbomination demons]].
demons]].
** In the main ''Franchise/ShinMegamiTensei'' series, human-demon fusion is quite likely to leave you like this, in ''IV'', some of the poor bastards who chose to become Demonoids were hit with ''Fusion Errors''. If you're not careful with Reds, in the same game, you will end up as a shambling undead. Or worse. Technically speaking, [[ShinMegamiTenseiIIINocturne the Demi-Fiend]] is also an example, as the parasite warped his body into that of a demon, even if he still closely resembles his human form, the horn he got was noted by WordOfGod to be a primitive sensory organ that grants him much of his demonic power, and the {{Power Tattoo}}s are actually lines of demonic lymph coursing through his body.
** In the main ''Franchise/ShinMegamiTensei'' series, human-demon fusion is quite likely to leave you like this, in ''IV'', some of the poor bastards who chose to become Demonoids were hit with ''Fusion Errors''. If you're not careful with Reds, in the same game, you will end up as a shambling undead. Or worse. Technically speaking, [[ShinMegamiTenseiIIINocturne the Demi-Fiend]] is also an example, as the parasite warped his body into that of a demon, even if he still closely resembles his human form, the horn he got was noted by WordOfGod to be a primitive sensory organ that grants him much of his demonic power, and the {{Power Tattoo}}s are actually lines of demonic lymph coursing through his body.
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* In ''VideoGame/DigitalDevilSaga'', everyone infected by the demon virus has access to demon form, which is stronger than human form. Said demon form ranges from looking vaguely humanoid (most of the main characters) to slimes to the [[EldritchAbomination worst looking of]] Franchise/ShinMegamiTensei [[EldritchAbomination demons]].
to:
* In ''VideoGame/DigitalDevilSaga'', everyone infected by the demon virus has access to demon form, which is stronger than human form. Said demon form ranges from looking vaguely humanoid (most of the main characters) characters), to slimes slimes, to animalistic, to the [[EldritchAbomination worst looking of]] Franchise/ShinMegamiTensei ''Franchise/ShinMegamiTensei'' [[EldritchAbomination demons]].demons]].
** In the main ''Franchise/ShinMegamiTensei'' series, human-demon fusion is quite likely to leave you like this, in ''IV'', some of the poor bastards who chose to become Demonoids were hit with ''Fusion Errors''. If you're not careful with Reds, in the same game, you will end up as a shambling undead. Or worse.
** In the main ''Franchise/ShinMegamiTensei'' series, human-demon fusion is quite likely to leave you like this, in ''IV'', some of the poor bastards who chose to become Demonoids were hit with ''Fusion Errors''. If you're not careful with Reds, in the same game, you will end up as a shambling undead. Or worse.
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* In ''Literature/{{A Macabre Myth of a Moth-Man}}, both the titular Moth-man and Ozzy were horrifically mutated (they both used to be normal guys), but also became much more powerful as a result.
to:
* In ''Literature/{{A Macabre Myth of a Moth-Man}}, Moth-Man}}'', both the titular Moth-man and Ozzy were horrifically mutated (they both used to be normal guys), but also became much more powerful as a result.
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* In the live action ''Film/StreetFighter'' movie, the project behind creating Blanca is basically an attempt at creating mutant {{Super Soldier}}s and brainwashing them.
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* In the live action ''Film/StreetFighter'' movie, the project behind creating Blanca is basically an attempt at creating mutant {{Super Soldier}}s and brainwashing them.
them.
[[AC: {{Literature}}]]
* In ''Literature/{{A Macabre Myth of a Moth-Man}}, both the titular Moth-man and Ozzy were horrifically mutated (they both used to be normal guys), but also became much more powerful as a result.
[[AC: {{Literature}}]]
* In ''Literature/{{A Macabre Myth of a Moth-Man}}, both the titular Moth-man and Ozzy were horrifically mutated (they both used to be normal guys), but also became much more powerful as a result.
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--> -- '''Zarbon''', ''Manga/DragonBall''
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--> -- '''Zarbon''', ''Manga/DragonBall''
''Anime/DragonBallZ''
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* Zarbon in ''Manga/DragonBall Z'' has a powerful second form, but it makes him look fat and ugly (whereas his normal form is a GorgeousGeorge type), so as a matter of vanity he avoids using it.
to:
* Zarbon in ''Manga/DragonBall Z'' ''Anime/DragonBallZ'' has a powerful second form, but it makes him look fat and ugly (whereas his normal form is a GorgeousGeorge type), so as a matter of vanity he avoids using it.
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* ''WesternAnimation/{{Kaijudo}}'' has the Choten's evolution drug, which transofrms the series' normally one-form {{Mons}} into a new, stronger form.
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* ''WesternAnimation/{{Kaijudo}}'' has the Choten's [[BigBad The Choten's]] evolution drug, which transofrms transforms the series' normally one-form {{Mons}} into a new, stronger form.
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* TheBindingOfIsaac has this as the de jour - nearly half the permanent items upgrade Isaac at the cost of visually maiming him. For example, a coat hangar [[EyeScream goes straight through Issac's eye socket to increase the firing rate of his tears.]]
to:
* TheBindingOfIsaac has this as the de jour - nearly half the permanent items upgrade Isaac at the cost of visually maiming him. For example, a coat hangar [[EyeScream goes straight through Issac's Isaac's eye socket to increase the firing rate of his tears.]]
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* TheBindingOfIssac has this as the de jour - nearly half the permanent items upgrade Issac at the cost of visually maiming him. For example, a coat hangar [[EyeScream goes straight through Issac's eye socket to increase the firing rate of his tears.]]
to:
* TheBindingOfIssac TheBindingOfIsaac has this as the de jour - nearly half the permanent items upgrade Issac Isaac at the cost of visually maiming him. For example, a coat hangar [[EyeScream goes straight through Issac's eye socket to increase the firing rate of his tears.]]
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adding example
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* TheBindingOfIssac has this as the de jour - nearly half the permanent items upgrade Issac at the cost of visually maiming him. For example, a coat hangar [[EyeScream goes straight through Issac's eye socket to increase the firing rate of his tears.]]
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typo
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* In ''Manga/{{Claymore}},'' this is how the titular SuperSoldiers are made, grafting in a piece of demon flesh to give them some of it's powers, but they eventually succumb to TheCorruption, if they don't give in to their SuperpoweredEvilSide.
to:
* In ''Manga/{{Claymore}},'' this is how the titular SuperSoldiers are made, grafting in a piece of demon flesh to give them some of it's its powers, but they eventually succumb to TheCorruption, if they don't give in to their SuperpoweredEvilSide.
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* Dr. N. Brio's appearances in the ''Franchise/CrashBandicoot'' series usually involve him drinking mutagen and turning into a [[ComicBook/IncredibleHulk hulking green monster]] (though by the time of ''Crash: Mind Over Mutant'', it seems like he needs the mutagen to ''keep'' from transforming). [[spoiler:At the end of Mind Over Mutant, Dr. Cortex samples the mutagen himself, with similar results.]]
to:
* Dr. N. Brio's appearances in the ''Franchise/CrashBandicoot'' series usually involve him drinking mutagen [[PsychoSerum mutagen]] and turning into a [[ComicBook/IncredibleHulk hulking green monster]] (though by the time of ''Crash: Mind Over Mutant'', it seems like he needs the mutagen to ''keep'' from transforming). [[spoiler:At the end of Mind Over Mutant, Dr. Cortex samples the mutagen himself, with similar results.]]
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* In ''VideoGame/DigitalDevilSaga'', everyone infected by the demon virus has access to demon form, which is stronger than human form. Said demon form ranges from looking vaguely humanoid (most of the main characters) to slimes to the [[EldritchAbomination worst looking of]] Franchise/ShinMegamiTensei [[EldritchAbomination demons]].
to:
* In ''VideoGame/DigitalDevilSaga'', everyone infected by the demon virus has access to demon form, which is stronger than human form. Said demon form ranges from looking vaguely humanoid (most of the main characters) to slimes to the [[EldritchAbomination worst looking of]] Franchise/ShinMegamiTensei [[EldritchAbomination demons]].
demons]].
* Dr. N. Brio's appearances in the ''Franchise/CrashBandicoot'' series usually involve him drinking mutagen and turning into a [[ComicBook/IncredibleHulk hulking green monster]] (though by the time of ''Crash: Mind Over Mutant'', it seems like he needs the mutagen to ''keep'' from transforming). [[spoiler:At the end of Mind Over Mutant, Dr. Cortex samples the mutagen himself, with similar results.]]
* Dr. N. Brio's appearances in the ''Franchise/CrashBandicoot'' series usually involve him drinking mutagen and turning into a [[ComicBook/IncredibleHulk hulking green monster]] (though by the time of ''Crash: Mind Over Mutant'', it seems like he needs the mutagen to ''keep'' from transforming). [[spoiler:At the end of Mind Over Mutant, Dr. Cortex samples the mutagen himself, with similar results.]]
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** In 40K, most augmetics (metal replacement parts, ranging from bionic eyes to replacement arms to [[{{Spider-Man}} Doctor Octopus]]-[[SpiderLimbs style dendrites]]) are rather crude and ugly (ork versions are even worse). The Adeptus Mechanicus see the replacement of flesh with metal as the ultimate way to better themselves, so naturally they get [[UncannyValley the worst reactions]] from normal humans.
to:
** In 40K, most augmetics (metal replacement parts, ranging from bionic eyes to replacement arms to [[{{Spider-Man}} Doctor Octopus]]-[[SpiderLimbs style dendrites]]) are rather crude and ugly (ork versions are even worse). The Adeptus Mechanicus see the replacement of flesh with metal as the ultimate way to better themselves, so naturally they get [[UncannyValley the worst reactions]] from normal humans.
humans.
** Even becoming a Space Marine, the de facto "heroes" of the 40K universe, involves some pretty gruesome procedures, like the addition of extra organs, genetic modifications that lead to superhuman size and musculature, metallic/ceramic replacements for your skeleton, and an implanted "second skin" that interfaces with your PoweredArmor. Worse still, many of these upgrades are based on non-renewable implants that have to be harvested from dead Space Marines so they can be passed on to new recruits!
** Even becoming a Space Marine, the de facto "heroes" of the 40K universe, involves some pretty gruesome procedures, like the addition of extra organs, genetic modifications that lead to superhuman size and musculature, metallic/ceramic replacements for your skeleton, and an implanted "second skin" that interfaces with your PoweredArmor. Worse still, many of these upgrades are based on non-renewable implants that have to be harvested from dead Space Marines so they can be passed on to new recruits!
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* In ''Manga/{{Claymore}},'' this is how the titular SuperSoldiers are made, grafting in a peice of demon flesh to give them some of it's powers, but they eventually succumb to TheCorruption, if they don't give in to their SuperpoweredEvilSide.
to:
* In ''Manga/{{Claymore}},'' this is how the titular SuperSoldiers are made, grafting in a peice piece of demon flesh to give them some of it's powers, but they eventually succumb to TheCorruption, if they don't give in to their SuperpoweredEvilSide.
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* In the {{New 52}} reboot of ''AnimalMan'', Buddy Baker now actually physically changes shape when he uses animal powers. The transformations are NOT pretty.
to:
* In the {{New 52}} reboot of ''AnimalMan'', ''ComicBook/AnimalMan'', Buddy Baker now actually physically changes shape when he uses animal powers. The transformations are NOT pretty.
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* The basis for Splicers in both ''Franchise/BioShock'' games. The use [[MagicFromTechnology a drug-like genetic modification enabler called ADAM that allows them to use superpowers]], but withdrawl disfigures them and drives them insane.
to:
* The basis for Splicers in both the first two ''Franchise/BioShock'' games. The use [[MagicFromTechnology Specifically, they were users of a drug-like genetic modification enabler gene-modifying substance called ADAM ADAM- and along with the many cosmetic uses that allows them to use superpowers]], but withdrawl disfigures them it can be applied to, specially-prepared batches can give the user superpowers in the form of plasmids; unfortunately, abuse of the substance has resulted in addiction, disfiguration, and drives them insane. insanity. The main characters can also suffer a few of the tamer side-effects when they have plasmids equipped: [[PlayingWithFire Incinerate!]] clearly burns the wielder's hand; [[AnIcePerson Winter Blast]] causes icicles to grow through the user's flesh (complete with blood); finally, [[BeeBeeGun Insect Swarm]] results in a mixture of nasty-looking stings across the hand (in Jack's case) or a honeycomb forming out of the palm (in Delta's case).
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Compare DangerousForbiddenTechnique, EvolutionPowerup, OneWingedAngel, and TransformationOfThePossessed. See also DeadlyUpgrade. Pretty much all {{Lovecraftian Superpower}}s result in this.
to:
Compare DangerousForbiddenTechnique, EvolutionPowerup, OneWingedAngel, and TransformationOfThePossessed. See also BeautyToBeast and DeadlyUpgrade. Pretty much all {{Lovecraftian Superpower}}s result in this.
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* The basis for Splicers in both ''VideoGame/BioShock'' games. The use [[MagicFromTechnology a drug-like genetic modification enabler called ADAM that allows them to use superpowers]], but withdrawl disfigures them and drives them insane.
to:
* The basis for Splicers in both ''VideoGame/BioShock'' ''Franchise/BioShock'' games. The use [[MagicFromTechnology a drug-like genetic modification enabler called ADAM that allows them to use superpowers]], but withdrawl disfigures them and drives them insane.
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-->- '''Zarbon''', ''Manga/DragonBall''
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->''You saw the beauty side of me before! Now, with great pleasure, I introduce you to the BEAST!''
-->- '''Zarbon''', ''Manga/DragonBall''
-->- '''Zarbon''', ''Manga/DragonBall''
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* Zarbon in ''Manga/DragonballZ'' has a powerful second form, but it makes him look fat and ugly (whereas his normal form is a GorgeousGeorge type), so as a matter of vanity he avoids using it.
to:
* Zarbon in ''Manga/DragonballZ'' ''Manga/DragonBall Z'' has a powerful second form, but it makes him look fat and ugly (whereas his normal form is a GorgeousGeorge type), so as a matter of vanity he avoids using it.
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* The splicers in ''BatmanBeyond'' used genetic engineering to become {{Half Human Hybrid}}s, which generally while animalistic weren't ugly. When their boss fights Terry, he takes a boat load of them and goes OneWingedAngel... until Terry gives him a ''second'' round of drugs which pushes him into ClippedWingAngel.
to:
* The splicers in ''BatmanBeyond'' ''WesternAnimation/BatmanBeyond'' used genetic engineering to become {{Half Human Hybrid}}s, which generally while animalistic weren't ugly. When their boss fights Terry, he takes a boat load of them and goes OneWingedAngel... until Terry gives him a ''second'' round of drugs which pushes him into ClippedWingAngel.
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* ''Manga/{{Berserk}}'': When [[EliteMook Zondark]] [[CurbStompBattle is unable to defeat]] [[AntiHero Guts]], [[AristocratsAreEvil the Count]] makes him [[OrificeInvasion swallow a part of him]]. This not only makes Zondark physically more powerful, but gives him the ability to grow CombatTentacles to replace lost limbs. The Count himself is one of the many [[OurDemonsAreDifferent Apostles]], [[DealWithTheDevil who have all been]] [[WasOnceAMan originally human]]. The Apostles can assume a human form but when they go OneWingedAngel [[BodyHorror "deformed"]] [[HighOctaneNightmareFuel is an]] [[EldritchAbomination understatement]].
to:
* ''Manga/{{Berserk}}'': When [[EliteMook Zondark]] [[CurbStompBattle is unable to defeat]] [[AntiHero Guts]], [[AristocratsAreEvil the Count]] makes him [[OrificeInvasion swallow a part of him]]. This not only makes Zondark physically more powerful, but gives him the ability to grow CombatTentacles to replace lost limbs. The Count himself is one of the many [[OurDemonsAreDifferent Apostles]], [[DealWithTheDevil who have all been]] [[WasOnceAMan originally human]]. The Apostles can assume a human form but when they go OneWingedAngel [[BodyHorror "deformed"]] [[HighOctaneNightmareFuel is an]] [[EldritchAbomination is an understatement]].
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* ''Manga/{{Bleach}}'' gives us Ichigo's Hollowfication, as well as the Vizoreds who have similar powers. By tapping into their inner Hollow, they gain immense strength and speed, but have a bone-like demonic looking mask grafted onto their faces in the process. It is only temporary though. The mask can be broken off in battle, and it'll eventually crumble away in time. The mask's appearance varies from person to person, but all of them stop looking human.
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* {{Marvel}}'s ''Comicbook/TheIncredibleHulk'', Dr Banner transforms into a giant green rage monster and has mega strength.
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* {{Marvel}}'s Creator/{{Marvel|Comics}}'s ''Comicbook/TheIncredibleHulk'', Dr Banner transforms into a giant green rage monster and has mega strength.
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* The ''FantasticFour'''s The Thing is perhaps one of MarvelComics most iconic examples. After passing through a cloud of cosmic radiation he grew a [[SuperToughness super tough rock-like hide]] and SuperStrength to match. The downside is that unlike Reed, Sue and Johnny he ''can't'' turn his powers on and off, and is always the same huge frightening rock monster; an issue which has caused him no end of grief and in some continuities even suicide attempts.
to:
* The ''FantasticFour'''s ''ComicBook/FantasticFour'''s The Thing is perhaps one of MarvelComics Creator/MarvelComics most iconic examples. After passing through a cloud of cosmic radiation he grew a [[SuperToughness super tough rock-like hide]] and SuperStrength to match. The downside is that unlike Reed, Sue and Johnny he ''can't'' turn his powers on and off, and is always the same huge frightening rock monster; an issue which has caused him no end of grief and in some continuities even suicide attempts.
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A Power Upgrading Deformation will make a character or creature much stronger but also make them look at the [[UncannyValley least]] [[WhatMeasureIsANonHuman inhuman]] and at the [[BodyHorror worst]] [[EldritchAbomination horrendous]]. Unlike the PsychoSerum where an ugly appearance is a side effect, for the Power Upgrading Deformation the newly ugly appearance is the ''source'' of the enhancement: like sprouting CombatTentacles, pincers, [[GrowingMusclesSequence supermassive muscles]], MyBrainIsBig, [[TheGrotesque grotesque]] {{Cyb|org}}ernetics, etc. Because of this it would technically still be considered a MagicEnhancement or SuperSerum and not PsychoSerum.
to:
A Power Upgrading Deformation will make a character or creature much stronger but also make them look at the [[UncannyValley least]] [[WhatMeasureIsANonHuman inhuman]] and at the [[BodyHorror worst]] [[EldritchAbomination horrendous]]. Unlike the PsychoSerum where an ugly appearance is can be a side effect, for the Power Upgrading Deformation the newly ugly appearance is the ''source'' of the enhancement: like sprouting CombatTentacles, pincers, [[GrowingMusclesSequence supermassive muscles]], MyBrainIsBig, [[TheGrotesque grotesque]] {{Cyb|org}}ernetics, etc. Because of this it would technically still be considered a MagicEnhancement or SuperSerum and not PsychoSerum.
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Compare DangerousForbiddenTechnique, EvolutionPowerup, OneWingedAngel, and TransformationOfThePossessed
. See also DeadlyUpgrade. Pretty much all {{Lovecraftian Superpower}}s result in this.
. See also DeadlyUpgrade. Pretty much all {{Lovecraftian Superpower}}s result in this.
to:
Compare DangerousForbiddenTechnique, EvolutionPowerup, OneWingedAngel, and TransformationOfThePossessed
.TransformationOfThePossessed. See also DeadlyUpgrade. Pretty much all {{Lovecraftian Superpower}}s result in this.
.
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* The ''FantasticFour'''s The Thing is perhaps one of MarvelComics most iconic examples. After passing through a cloud of cosmic radiation he grew a [[SuperToughness super tough rock-like hide]] and SuperStrength to match. The downside is that unlike Reed, Sue and Johnny he ''can't'' turn his powers on and off, and is always the same huge frightening rock monster; an issue which has caused him no end of grief and in some continuities even suicide attempts.
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Cross linking
Changed line(s) 10,11 (click to see context) from:
Compare DangerousForbiddenTechnique, EvolutionPowerup and OneWingedAngel. See also DeadlyUpgrade. Pretty much all {{Lovecraftian Superpower}}s result in this.
to:
Compare DangerousForbiddenTechnique, EvolutionPowerup EvolutionPowerup, OneWingedAngel, and OneWingedAngel.TransformationOfThePossessed
. See also DeadlyUpgrade. Pretty much all {{Lovecraftian Superpower}}s result in this.
. See also DeadlyUpgrade. Pretty much all {{Lovecraftian Superpower}}s result in this.
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Compare DangerousForbiddenTechnique, EvolutionPowerup and OneWingedAngel. See also DeadlyUpgrade.
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Compare DangerousForbiddenTechnique, EvolutionPowerup and OneWingedAngel. See also DeadlyUpgrade. \n Pretty much all {{Lovecraftian Superpower}}s result in this.
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[[quoteright:350:[TabletopGame/MagicTheGathering http://static.tvtropes.org/pmwiki/pub/images/Transmutation2_3337.jpg]]]]
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[[quoteright:269:[[TabletopGame/MagicTheGathering http://static.tvtropes.org/pmwiki/pub/images/Transmutation2_3337.jpg]]]]
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Added DiffLines:
----
!!Examples:
!!Examples:
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[[quoteright:269:[[TabletopGame/MagicTheGathering http://static.tvtropes.org/pmwiki/pub/images/Transmutation2_3337.jpg]]]]
[[caption-width-right:350:[[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=2819 This]] [[HurricaneOfPuns fairy's tale just got very point-nant.]]]]
A Power Upgrading Deformation will make a character or creature much stronger but also make them look at the [[UncannyValley least]] [[WhatMeasureIsANonHuman inhuman]] and at the [[BodyHorror worst]] [[EldritchAbomination horrendous]]. Unlike the PsychoSerum where an ugly appearance is a side effect, for the Power Upgrading Deformation the newly ugly appearance is the ''source'' of the enhancement: like sprouting CombatTentacles, pincers, [[GrowingMusclesSequence supermassive muscles]], MyBrainIsBig, [[TheGrotesque grotesque]] {{Cyb|org}}ernetics, etc. Because of this it would technically still be considered a MagicEnhancement or SuperSerum and not PsychoSerum.
If the setting has a BishonenLine, this drug, technology or spell will take the character to ''just'' before the return to prettiness (or if already there, start the cycle over). It's also worth noting that protagonists and main villains may get off easy with [[ButYourWingsAreBeautiful cool looking alterations]] that are [[OneWingedAngel way more]] [[SuperMode powerful]] while {{Mooks}} and secondary characters aren't so lucky.
The deformation may be a mix of: permanent (requiring a cure to remove) or temporary (granting a SuperMode), and perfectly stable (no more {{muta|nt}}tions) or continuously changing (risking falling to TheCorruption or PowerDegeneration). Because its effects are so nasty taking it tends to be treated as a GodzillaThreshold, with [[EmergencyTransformation only the direst of situations meriting it]]. Villains like the MadScientist and EvilutionaryBiologist will delight in kidnapping victims to use this on... usually paired with a MindControlDevice of course! [[note]](Can't have a PhlebotinumRebel, now can we?)[[/note]] On the other hand, some villains may [[ProfessorGuineaPig take it themselves]], become a OneWingedAngel and proclaim AGodAmI! Truly, EvilMakesYouMonstrous. Mind the ClippedWingAngel from overdosing.
Compare DangerousForbiddenTechnique, EvolutionPowerup and OneWingedAngel. See also DeadlyUpgrade.
[[AC: Anime and Manga]]
* ''Manga/{{Berserk}}'': When [[EliteMook Zondark]] [[CurbStompBattle is unable to defeat]] [[AntiHero Guts]], [[AristocratsAreEvil the Count]] makes him [[OrificeInvasion swallow a part of him]]. This not only makes Zondark physically more powerful, but gives him the ability to grow CombatTentacles to replace lost limbs. The Count himself is one of the many [[OurDemonsAreDifferent Apostles]], [[DealWithTheDevil who have all been]] [[WasOnceAMan originally human]]. The Apostles can assume a human form but when they go OneWingedAngel [[BodyHorror "deformed"]] [[HighOctaneNightmareFuel is an]] [[EldritchAbomination understatement]].
* In ''Manga/{{Claymore}},'' this is how the titular SuperSoldiers are made, grafting in a peice of demon flesh to give them some of it's powers, but they eventually succumb to TheCorruption, if they don't give in to their SuperpoweredEvilSide.
* The Tavoo/Taboo race in ''Manga/{{Psyren}}'' all have a core known as an Illuminus, which heightens their psionic abilities, but often disfigures them to the point of not even looking human anymore, usually taking on an [[EverythingsWorseWithBees insectoid]] appearance instead. The few exceptions are the high-ranking W.I.S.E. members, [[DoubleStandard and several others such as Tatsuo and Alfred.]]
* Similar to ''Claymore'' example, if the [[spoiler:Magical Girls]] of ''Anime/PuellaMagiMadokaMagica'' falls into DespairEventHorizon, they will turn into [[spoiler: [[EldritchAbomination Witches]]]]. This is actually a [[SubvertedTrope subversion]], since [[spoiler:Witches]] lose their sanity and acts purely on instinct, making them less effective in actual combat.
* The Zoanoids in ''{{Guyver}}'' are basically mutated humans whose new (revolting) forms are always tailored to give them a specific strength or super attack. [[MonsterLord Zoalords]] are however higher on the BishonenLine and look far less ugly than their underlings.
* Zarbon in ''Manga/DragonballZ'' has a powerful second form, but it makes him look fat and ugly (whereas his normal form is a GorgeousGeorge type), so as a matter of vanity he avoids using it.
[[AC:ComicBooks]]
* In TheNewUniverse in general and ''Comicbook/{{DP7}}'' in particular, [[MassEmpoweringEvent the White Event]] makes people suddenly have power-related mutations, many of which are like this. Moreso minor characters than the main ones, which [[CursedWithAwesome for all their complaints are really not that bad]].
* {{Marvel}}'s ''Comicbook/TheIncredibleHulk'', Dr Banner transforms into a giant green rage monster and has mega strength.
* In the {{New 52}} reboot of ''AnimalMan'', Buddy Baker now actually physically changes shape when he uses animal powers. The transformations are NOT pretty.
[[AC:{{Film}}]]
* In ''Franchise/PiratesOfTheCaribbean'', Davy Jones and his crew are immortal, but have spent so long neglecting their job of {{Psychopomp}} for the dead at sea that they've become [[HalfHumanHybrid half-morphed into sea creatures.]]
* In the live action ''Film/StreetFighter'' movie, the project behind creating Blanca is basically an attempt at creating mutant {{Super Soldier}}s and brainwashing them.
[[AC:TabletopRPG]]
* Just about every Chaos mutation in ''[[TabletopGame/{{Warhammer}} Warhammer Fantasy]]'' and ''TabletopGame/Warhammer40K'', since these mutations include things like CombatTentacles, pincers, extra mouths, cancerous growths...
** In 40K, most augmetics (metal replacement parts, ranging from bionic eyes to replacement arms to [[{{Spider-Man}} Doctor Octopus]]-[[SpiderLimbs style dendrites]]) are rather crude and ugly (ork versions are even worse). The Adeptus Mechanicus see the replacement of flesh with metal as the ultimate way to better themselves, so naturally they get [[UncannyValley the worst reactions]] from normal humans.
[[AC:{{Toys}}]]
* In the fifth story line of ''Franchise/{{Bionicle}}'', the Toa Metru are captured and injected with [[TheCorruption Hordika venom]], which turns them into [[BeastMan half-animals]]. [[DownplayedTrope Downplayed]] in that while greatly increasing their physical strength, it also degrades their elemental abilities to some extent.
[[AC:VideoGames]]
* The basis for Splicers in both ''VideoGame/BioShock'' games. The use [[MagicFromTechnology a drug-like genetic modification enabler called ADAM that allows them to use superpowers]], but withdrawl disfigures them and drives them insane.
* This comes up in ''VideoGame/DeusEx''; some cyborgs dislike the protagonist because they had to sacrifice their ability to look normal (thanks to the fairly obvious nature of their implants) while the protagonist's nanomachine based augments have barely any cosmetic effects (not to mention rendered them obsolete).
* [[EldritchAbomination Bydo]]-derived OrganicTechnology from ''VideoGame/{{R-Type}}'', under certain circumstances. For example, if the Claw Force is detached from the fighter too long, it temporarily mutates and goes on a rampage.
* In ''VideoGame/DigitalDevilSaga'', everyone infected by the demon virus has access to demon form, which is stronger than human form. Said demon form ranges from looking vaguely humanoid (most of the main characters) to slimes to the [[EldritchAbomination worst looking of]] Franchise/ShinMegamiTensei [[EldritchAbomination demons]].
[[AC:WesternAnimation]]
* ''WesternAnimation/{{Kaijudo}}'' has the Choten's evolution drug, which transofrms the series' normally one-form {{Mons}} into a new, stronger form.
* ''WesternAnimation/StreetSharks'' has the gene splicing treatment that turns humans into sharks (and sea animals into monsters).
* Every ''Franchise/TeenageMutantNinjaTurtles'' cartoon had the mutagenic ooze which made them more human-like, while also mutating humans into uglier mutants.
* The splicers in ''BatmanBeyond'' used genetic engineering to become {{Half Human Hybrid}}s, which generally while animalistic weren't ugly. When their boss fights Terry, he takes a boat load of them and goes OneWingedAngel... until Terry gives him a ''second'' round of drugs which pushes him into ClippedWingAngel.
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[[caption-width-right:350:[[http://gatherer.wizards.com/Pages/Card/Details.aspx?multiverseid=2819 This]] [[HurricaneOfPuns fairy's tale just got very point-nant.]]]]
A Power Upgrading Deformation will make a character or creature much stronger but also make them look at the [[UncannyValley least]] [[WhatMeasureIsANonHuman inhuman]] and at the [[BodyHorror worst]] [[EldritchAbomination horrendous]]. Unlike the PsychoSerum where an ugly appearance is a side effect, for the Power Upgrading Deformation the newly ugly appearance is the ''source'' of the enhancement: like sprouting CombatTentacles, pincers, [[GrowingMusclesSequence supermassive muscles]], MyBrainIsBig, [[TheGrotesque grotesque]] {{Cyb|org}}ernetics, etc. Because of this it would technically still be considered a MagicEnhancement or SuperSerum and not PsychoSerum.
If the setting has a BishonenLine, this drug, technology or spell will take the character to ''just'' before the return to prettiness (or if already there, start the cycle over). It's also worth noting that protagonists and main villains may get off easy with [[ButYourWingsAreBeautiful cool looking alterations]] that are [[OneWingedAngel way more]] [[SuperMode powerful]] while {{Mooks}} and secondary characters aren't so lucky.
The deformation may be a mix of: permanent (requiring a cure to remove) or temporary (granting a SuperMode), and perfectly stable (no more {{muta|nt}}tions) or continuously changing (risking falling to TheCorruption or PowerDegeneration). Because its effects are so nasty taking it tends to be treated as a GodzillaThreshold, with [[EmergencyTransformation only the direst of situations meriting it]]. Villains like the MadScientist and EvilutionaryBiologist will delight in kidnapping victims to use this on... usually paired with a MindControlDevice of course! [[note]](Can't have a PhlebotinumRebel, now can we?)[[/note]] On the other hand, some villains may [[ProfessorGuineaPig take it themselves]], become a OneWingedAngel and proclaim AGodAmI! Truly, EvilMakesYouMonstrous. Mind the ClippedWingAngel from overdosing.
Compare DangerousForbiddenTechnique, EvolutionPowerup and OneWingedAngel. See also DeadlyUpgrade.
[[AC: Anime and Manga]]
* ''Manga/{{Berserk}}'': When [[EliteMook Zondark]] [[CurbStompBattle is unable to defeat]] [[AntiHero Guts]], [[AristocratsAreEvil the Count]] makes him [[OrificeInvasion swallow a part of him]]. This not only makes Zondark physically more powerful, but gives him the ability to grow CombatTentacles to replace lost limbs. The Count himself is one of the many [[OurDemonsAreDifferent Apostles]], [[DealWithTheDevil who have all been]] [[WasOnceAMan originally human]]. The Apostles can assume a human form but when they go OneWingedAngel [[BodyHorror "deformed"]] [[HighOctaneNightmareFuel is an]] [[EldritchAbomination understatement]].
* In ''Manga/{{Claymore}},'' this is how the titular SuperSoldiers are made, grafting in a peice of demon flesh to give them some of it's powers, but they eventually succumb to TheCorruption, if they don't give in to their SuperpoweredEvilSide.
* The Tavoo/Taboo race in ''Manga/{{Psyren}}'' all have a core known as an Illuminus, which heightens their psionic abilities, but often disfigures them to the point of not even looking human anymore, usually taking on an [[EverythingsWorseWithBees insectoid]] appearance instead. The few exceptions are the high-ranking W.I.S.E. members, [[DoubleStandard and several others such as Tatsuo and Alfred.]]
* Similar to ''Claymore'' example, if the [[spoiler:Magical Girls]] of ''Anime/PuellaMagiMadokaMagica'' falls into DespairEventHorizon, they will turn into [[spoiler: [[EldritchAbomination Witches]]]]. This is actually a [[SubvertedTrope subversion]], since [[spoiler:Witches]] lose their sanity and acts purely on instinct, making them less effective in actual combat.
* The Zoanoids in ''{{Guyver}}'' are basically mutated humans whose new (revolting) forms are always tailored to give them a specific strength or super attack. [[MonsterLord Zoalords]] are however higher on the BishonenLine and look far less ugly than their underlings.
* Zarbon in ''Manga/DragonballZ'' has a powerful second form, but it makes him look fat and ugly (whereas his normal form is a GorgeousGeorge type), so as a matter of vanity he avoids using it.
[[AC:ComicBooks]]
* In TheNewUniverse in general and ''Comicbook/{{DP7}}'' in particular, [[MassEmpoweringEvent the White Event]] makes people suddenly have power-related mutations, many of which are like this. Moreso minor characters than the main ones, which [[CursedWithAwesome for all their complaints are really not that bad]].
* {{Marvel}}'s ''Comicbook/TheIncredibleHulk'', Dr Banner transforms into a giant green rage monster and has mega strength.
* In the {{New 52}} reboot of ''AnimalMan'', Buddy Baker now actually physically changes shape when he uses animal powers. The transformations are NOT pretty.
[[AC:{{Film}}]]
* In ''Franchise/PiratesOfTheCaribbean'', Davy Jones and his crew are immortal, but have spent so long neglecting their job of {{Psychopomp}} for the dead at sea that they've become [[HalfHumanHybrid half-morphed into sea creatures.]]
* In the live action ''Film/StreetFighter'' movie, the project behind creating Blanca is basically an attempt at creating mutant {{Super Soldier}}s and brainwashing them.
[[AC:TabletopRPG]]
* Just about every Chaos mutation in ''[[TabletopGame/{{Warhammer}} Warhammer Fantasy]]'' and ''TabletopGame/Warhammer40K'', since these mutations include things like CombatTentacles, pincers, extra mouths, cancerous growths...
** In 40K, most augmetics (metal replacement parts, ranging from bionic eyes to replacement arms to [[{{Spider-Man}} Doctor Octopus]]-[[SpiderLimbs style dendrites]]) are rather crude and ugly (ork versions are even worse). The Adeptus Mechanicus see the replacement of flesh with metal as the ultimate way to better themselves, so naturally they get [[UncannyValley the worst reactions]] from normal humans.
[[AC:{{Toys}}]]
* In the fifth story line of ''Franchise/{{Bionicle}}'', the Toa Metru are captured and injected with [[TheCorruption Hordika venom]], which turns them into [[BeastMan half-animals]]. [[DownplayedTrope Downplayed]] in that while greatly increasing their physical strength, it also degrades their elemental abilities to some extent.
[[AC:VideoGames]]
* The basis for Splicers in both ''VideoGame/BioShock'' games. The use [[MagicFromTechnology a drug-like genetic modification enabler called ADAM that allows them to use superpowers]], but withdrawl disfigures them and drives them insane.
* This comes up in ''VideoGame/DeusEx''; some cyborgs dislike the protagonist because they had to sacrifice their ability to look normal (thanks to the fairly obvious nature of their implants) while the protagonist's nanomachine based augments have barely any cosmetic effects (not to mention rendered them obsolete).
* [[EldritchAbomination Bydo]]-derived OrganicTechnology from ''VideoGame/{{R-Type}}'', under certain circumstances. For example, if the Claw Force is detached from the fighter too long, it temporarily mutates and goes on a rampage.
* In ''VideoGame/DigitalDevilSaga'', everyone infected by the demon virus has access to demon form, which is stronger than human form. Said demon form ranges from looking vaguely humanoid (most of the main characters) to slimes to the [[EldritchAbomination worst looking of]] Franchise/ShinMegamiTensei [[EldritchAbomination demons]].
[[AC:WesternAnimation]]
* ''WesternAnimation/{{Kaijudo}}'' has the Choten's evolution drug, which transofrms the series' normally one-form {{Mons}} into a new, stronger form.
* ''WesternAnimation/StreetSharks'' has the gene splicing treatment that turns humans into sharks (and sea animals into monsters).
* Every ''Franchise/TeenageMutantNinjaTurtles'' cartoon had the mutagenic ooze which made them more human-like, while also mutating humans into uglier mutants.
* The splicers in ''BatmanBeyond'' used genetic engineering to become {{Half Human Hybrid}}s, which generally while animalistic weren't ugly. When their boss fights Terry, he takes a boat load of them and goes OneWingedAngel... until Terry gives him a ''second'' round of drugs which pushes him into ClippedWingAngel.
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