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* ''Series/MidsomerMurders'': The second VictimOfTheWeek in "Death in Disguise" is killed when the murderer deliberately withholds their heart medication as they suffer a heart attack.

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* ''Series/MidsomerMurders'': The second VictimOfTheWeek in "Death "[[Recap/MidsomerMurdersWroteS1E4 Death in Disguise" Disguise]]" is killed when the murderer deliberately withholds their heart medication as they suffer a heart attack.
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Chewing gum is a food product, not a medication, so this example would be Tampering With Food And Drink


* A ''Literature/{{Biggles}}'' story set during World War 2 involved the inexplicable crashes of multiple Allied aircraft flying a particular supply route. Japanese intelligence officers were slipping packets of chewing gum laced with a powerful narcotic into the cockpits of the planes, causing the pilots to pass out at the controls.
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* One of the Devil's [[EvilIsPetty random acts of petty evil]] on ''Film/Bedazzled2000'' is to exchange all of the medicines that are being readied to hand out to patients in a hospital with candies. One of the changes that are explicitly mentioned is that of someone's anti-psychotics being replaced with Tic-Tacs.

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* One of the Devil's [[EvilIsPetty random acts of petty evil]] on in ''Film/Bedazzled2000'' is to exchange all of the medicines that are being readied to hand out to patients in a hospital with candies. One of the changes that are explicitly mentioned is that of someone's anti-psychotics being replaced with Tic-Tacs.



* In ''Film/{{Shock}}'', Dr. Cross administers insulin shock therapy to Janet and intends to use the last dose as a cover to murdering her by insulin overdose.

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* In ''Film/{{Shock}}'', Dr. Cross administers insulin shock therapy to Janet and intends to use the last dose as a cover to murdering murder her by insulin overdose.



* In ''Literature/TheQueensThief'' book ''King of Attolia'', Eugenides' medicine is spiked with a dangerous hallucinogen that is used to induced oracular visions and can lead to death if misused--as well as screaming nightmares. [[spoiler:He put it there ''himself'' and didn't take it because he gets screaming nightmares anyway, and he needed to "expose" his chief attendant as a traitor without compromising his ability to secretly gather evidence for the way the attendant ''actually'' tried to murder him.]]

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* In ''Literature/TheQueensThief'' book ''King of Attolia'', Eugenides' medicine is spiked with a dangerous hallucinogen that is used to induced induce oracular visions and can lead to death if misused--as well as screaming nightmares. [[spoiler:He put it there ''himself'' and didn't take it because he gets screaming nightmares anyway, and he needed to "expose" his chief attendant as a traitor without compromising his ability to secretly gather evidence for the way the attendant ''actually'' tried to murder him.]]



** In "[[spoiler:Hidden Secrets]]", a doctor diagnoses his friend as suffering an incurable degenerative nerve disease, as part of a plot to [[DrivenToSuicide drive him to suicide]]. The drugs he supplies him to 'treat' the condition are actually antipsychotics that will simulate the symptoms of degenerative nerve damage.
** In "Wish You Weren't Here", the murderer kills his second victim by surreptitiously dumping a large amount of a heart medication the victim was already taking in his drink. Combined with his regular daily dose this was enough to trigger an overdose.

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** In "[[spoiler:Hidden Secrets]]", a doctor diagnoses his friend as suffering from an incurable degenerative nerve disease, as part of a plot to [[DrivenToSuicide drive him to suicide]]. The drugs he supplies him to 'treat' the condition are actually antipsychotics that will simulate the symptoms of degenerative nerve damage.
** In "Wish You Weren't Here", the murderer kills his second victim by surreptitiously dumping a large amount of a heart medication the victim was already taking in his drink. Combined with his regular daily dose this was enough to trigger an overdose.



* ''Series/ForensicFiles'': Yazeed Essa from "The Car Accident" killed his wife by slipping cyanide in her calcium supplements.
* ''Series/{{Gotham}}'': The father of Oswald Cobblepot explains to him that he has a heart condition, a hole in his heart that does not seems to resolve itself despite the medication he takes. His wife brings him the medication as he is explaining that, and after leaving the room takes the exact same white "pill" from a mints box and eats it.

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* ''Series/ForensicFiles'': Yazeed Essa from "The Car Accident" killed his wife by slipping cyanide in into her calcium supplements.
* ''Series/{{Gotham}}'': The father of Oswald Cobblepot explains to him that he has a heart condition, a hole in his heart that does not seems seem to resolve itself despite the medication he takes. His wife brings him the medication as he is explaining that, and after leaving the room takes the exact same white "pill" from a mints box and eats it.



* ''Series/{{Haven}}'': In "Ain't No sunshine", Rand and Wilson were withholding chemotherapy medication and selling it to other clinics, which led to the rapid death of Thornton's wife. This starts his Trouble, which kills them, although he does not appear to be aware that his shadow is actually ''killing'' people.

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* ''Series/{{Haven}}'': In "Ain't No sunshine", Sunshine", Rand and Wilson were withholding chemotherapy medication and selling it to other clinics, which led to the rapid death of Thornton's wife. This starts his Trouble, which kills them, although he does not appear to be aware that his shadow is actually ''killing'' people.



* ''Series/LawAndOrderCriminalIntent'': In "In Treatment", a psychiatrist gives one of his patients an antidepressant that he knows is contraindicated with the antidepressant he is currently taking. The combination causes a variety of side-effects, including delirium, which causes the patient to commit suicide.

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* ''Series/LawAndOrderCriminalIntent'': In "In Treatment", a psychiatrist gives one of his patients an antidepressant that he knows is contraindicated with the antidepressant he is currently taking. The combination causes a variety of side-effects, side effects, including delirium, which causes the patient to commit suicide.



* One episode of ''Series/{{Monk}}'' features a pharmacist who had murdered his partner years earlier and buried him on church grounds. When he learns the church is going to expand and dig up his partner, he concocts an elaborate hoax to convince the church that their fountain's waters are divine and heal people. He manages this by switching out the prescriptions he's supposed to be filling with sugar pills, so that the patients' conditions worsen. He then anonymously directs them to drink from the fountain's waters. Once he learns that they've taken the bait, he begins providing them with proper medication again. As far as they know, they've been getting the medicine the entire time, so they believe the fountain is responsible.

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* One episode of ''Series/{{Monk}}'' features a pharmacist who had murdered his partner years earlier and buried him on church grounds. When he learns the church is going to expand and dig up his partner, he concocts an elaborate hoax to convince the church that their fountain's waters are divine and heal people. He manages this by switching out the prescriptions he's supposed to be filling with sugar pills, pills so that the patients' conditions worsen. He then anonymously directs them to drink from the fountain's waters. Once he learns that they've taken the bait, he begins providing them with proper medication again. As far as they know, they've been getting the medicine the entire time, so they believe the fountain is responsible.



* ''Series/MyLifeIsMurder'': In "Mirror Mirror", the murderer laces the lidocaine cream being used on the VictimOfTheWeek's chest for a minor cosmetic procedure with barbiturates. This knocks the victim out several hours later and the killer force feeds her more barbiturates and then injects her with a fatal dose of botulinum toxin to make it look like a case of self-medication gone wrong.

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* ''Series/MyLifeIsMurder'': In "Mirror Mirror", the murderer laces the lidocaine cream being used on the VictimOfTheWeek's chest for a minor cosmetic procedure with barbiturates. This knocks the victim out several hours later and the killer force feeds force-feeds her more barbiturates and then injects her with a fatal dose of botulinum toxin to make it look like a case of self-medication gone wrong.



** The killer of "Sister morfine" by-passed the victim's automatic morphine pump by draining it with a syringe and subsequently injecting a month's dose of morphine into the victim.
* ''Series/TheWire'' mixing poison into heroin is used twice. First, when Avon Barksdale needs to get rid of a troublesome guard at the prison, so he has the package he is smuggling in to the prison poisoned leading to a rash of deaths overnight. Later, Bubbles tries to use potassium cyanide to get rid of a agressive junkie that robs him daily, but unfortunately his young protoge Sherrod snorts the vial when Bubbles is sleeping, and dies.

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** The killer of "Sister morfine" by-passed bypassed the victim's automatic morphine pump by draining it with a syringe and subsequently injecting a month's dose of morphine into the victim.
* ''Series/TheWire'' mixing poison into heroin is used twice. First, when Avon Barksdale needs to get rid of a troublesome guard at the prison, so he has the package he is smuggling in to into the prison poisoned leading to a rash of deaths overnight. Later, Bubbles tries to use potassium cyanide to get rid of a agressive an aggressive junkie that robs him daily, but unfortunately his young protoge protege Sherrod snorts the vial when Bubbles is sleeping, sleeping and dies.



* In ''WesternAnimation/KingOfTheHill'', Bobby tries to get even with Luanne when her then-boyfriend throws a party at Boomhauer's house which he was house-sitting. He set up pranks against Luanne and she retaliates back. Finally, he goes far enough to change Luanne's birth control pills with candy. Hank and Peggy decide to make Bobby "marry" Luanne to teach him a lesson.

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* In ''WesternAnimation/KingOfTheHill'', Bobby tries to get even with Luanne when her then-boyfriend throws a party at Boomhauer's house which where he was house-sitting. He set sets up pranks against Luanne and she retaliates back. Finally, he goes far enough to change Luanne's birth control pills with candy. Hank and Peggy decide to make Bobby "marry" Luanne to teach him a lesson.



* Sadly TruthInTelevision, where certain pain and anxiety medications that also get abused recreationally have become such high value that some dealers use pill presses to make bootleg pills, sometimes using Fentanyl, a strong synthetic opioid. Such bootleg pills have lead to the deaths of both Music/{{Prince}} and Music/MacMiller.

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* Sadly TruthInTelevision, where certain pain and anxiety medications that also get abused recreationally have become such high value that some dealers use pill presses to make bootleg pills, sometimes using Fentanyl, a strong synthetic opioid. Such bootleg pills have lead led to the deaths of both Music/{{Prince}} and Music/MacMiller.

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