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* ''Film/{{Pandorum}}'': The man-eating Hunters are presumed to have evolved from people who caught [[SpaceMadness space madness]] and turned into cannibals. Their evolution into feral predators was "accelerated" by artificial means.

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* ''Film/{{Pandorum}}'': The man-eating Hunters are presumed to have evolved from people who caught [[SpaceMadness space madness]] and turned into cannibals. Their evolution into feral predators was "accelerated" by artificial means.means, as the crew were meant to settle on another planet and given an enzyme that would help them adapt to it. In this case, they adapted to the conditions existing on the spaceship they were trapped on.
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* ''Film/ItTheTerrorFromBeyondSpace'' (1958). The crew theorizes that the monster could be part of the remnant of a Martian civilization that somehow destroyed itself and returned to prehistoric barbarism.

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* In ''Literature/AllTomorrows'', [[SufficientlyAdvancedAliens the Qu]] genetically engineer humans into a variety of non-sapient, animalistic forms and scatter them across the galaxy. Over time, many of them manage to re-evolve sapience.

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* In ''Literature/AllTomorrows'', ''Literature/AllTomorrows'': [[SufficientlyAdvancedAliens the Qu]] genetically engineer humans into a variety of non-sapient, animalistic forms and scatter them across the galaxy. Over time, many of them manage to re-evolve sapience.


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* ''Literature/OrphansOfTheSky'': By the time the novel takes place, the Crew has become so backward that they think the ship is the whole Universe, and live in what is essentially a feudal society consisting primarily of subsistence farmers ruled by a priestly caste of "Scientists", a nobility descended from the officers, and a king-like Captain. Even the concept of discrete time units has been lost, without days or seasons with which to divide timekeeping. The only reason that the ship still works is that its reactor[[note]]the secondary reactor, actually, the main one having gone kaput during the mutiny[[/note]] can convert any matter into energy at pretty much 100% efficiency. Everything that is no longer useful, including the dead, is used as fuel for the reactor. The Muties of the upper decks have regressed even farther, and now live as a loose scattering of raiders, squatters, and scavengers.

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* ''Film/FightClub'': {{Discussed}} in Tyler's vision for things to come:
--> In the world I see - you are stalking elk through the damp canyon forests around the ruins of Rockefeller Center. You'll wear leather clothes that will last you the rest of your life. You'll climb the wrist-thick kudzu vines that wrap the Sears Tower. And when you look down, you'll see tiny figures pounding corn, laying strips of venison on the empty car pool lane of some abandoned superhighway.

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* ''Film/FightClub'': {{Discussed}} {{Discussed|Trope}} in Tyler's vision for things to come:
--> -->'''Tyler:''' In the world I see - you are stalking elk through the damp canyon forests around the ruins of Rockefeller Center. You'll wear leather clothes that will last you the rest of your life. You'll climb the wrist-thick kudzu vines that wrap the Sears Tower. And when you look down, you'll see tiny figures pounding corn, laying strips of venison on the empty car pool lane of some abandoned superhighway.



** In the original book version of ''The Planet of the Apes'' Ulysse (the equivalent character of Taylor) teaches Nova how to talk and their son can talk from the get-go. Also TheReveal that [[spoiler:many many years ago apes were servants to humans]] is discovered through GeneticMemory in humans; when a certain portion of the brain is stimulated via electricity they can talk, recounting the stories of their ancestors which lead up to the [[spoiler:ape takeover]]. Also in the original book the humans run around nude rather than clad in skins (which no doubt was done to get the film past the censors).

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** In the original book version of ''The Planet of the Apes'' Apes'', Ulysse (the equivalent character of Taylor) teaches Nova how to talk and their son can talk from the get-go. Also TheReveal that [[spoiler:many many years ago apes were servants to humans]] is discovered through GeneticMemory in humans; when a certain portion of the brain is stimulated via electricity they can talk, recounting the stories of their ancestors which lead up to the [[spoiler:ape takeover]]. Also in the original book the humans run around nude rather than clad in skins (which no doubt was done to get the film past the censors).



* ''VideoGame/{{Battleborn}}'': Phoebe's DLC Story Operation reveals this to be the apparent case for the Tempestian Grayhorns of which the Thralls are derived from. Apparently the Thralls are [[spoiler: actually the [[{{Precursors}} ancient Aztanti]] at least on a genetic level. Based on some findings by Beatrix and the others over the course of the operation, it's uncovered that the once great Aztanti purposely de-evolved themselves into feral beasts. In the ancient past, the Aztanti were able to open a portal connecting to the Varelsi's universe. Although they were able to shut close the portal, they decided on a drastic course of action in hopes of preventing another open portal to the Void. They figured that even if they erased all records of how they opened a portal to another universe, their people would still be around to accidentally make the same mistake again in the future. So using a bespoke retrovirus tailored to rewrite segments of their genetic code, the Aztanti de-evolved themselves into feral beasts no different than mere animals. These beasts however retained dormant Aztanti traits that had the potential for greater strength, intelligence, and lifespans. In [[UpliftedAnimal force evolving]] the Thralls into their current state, Beatrix simply reawakened these dormant traits but just enough to make them into a SlaveRace for the Jennerit.]]
* ''Videogame/{{Diablo}}'': Humans are the descendants of an ancient race known as the [[{{Nephilim}} Nephalem]], who are described as a half-breed race born from forbidden unions between angels and demons, with [[ImmuneToFate no fixed destiny]] and limitless potential that even the mightiest Demon Lords and Archangels felt threatened by. The angels and demons who sired them became so afraid of them that they modified an artefact called the Worldstone into a PowerLimiter, causing the second generation on Nephalem to be born considerably weaker and with much shorter lifespans than the first. At the end of ''Videogame/DiabloII'', the Worldstone is corrupted and shattered, and 20 years later, [[HumansAreSpecial a small number of humans were starting to regain their Nephalem-like potential.]] Unfortunately, thanks to the actions of a renegade sect of angels, the vast majority of humanity was wiped out, severely slowing the restoration of humanity's ancestral potential. As of ''Videogame/DiabloIV'', fifty years afterwards, there have been no new cases of humans awakening Nephalem powers yet seen, forcing what remains of human society into the most primitive and diminished state it had been in thousands of years.

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* ''VideoGame/{{Battleborn}}'': Phoebe's DLC Story Operation reveals this to be the apparent case for the Tempestian Grayhorns of which the Thralls are derived from. Apparently the Thralls are [[spoiler: actually [[spoiler:actually the [[{{Precursors}} ancient Aztanti]] at least on a genetic level. Based on some findings by Beatrix and the others over the course of the operation, it's uncovered that the once great Aztanti purposely de-evolved themselves into feral beasts. In the ancient past, the Aztanti were able to open a portal connecting to the Varelsi's universe. Although they were able to shut close the portal, they decided on a drastic course of action in hopes of preventing another open portal to the Void. They figured that even if they erased all records of how they opened a portal to another universe, their people would still be around to accidentally make the same mistake again in the future. So using a bespoke retrovirus tailored to rewrite segments of their genetic code, the Aztanti de-evolved themselves into feral beasts no different than mere animals. These beasts however retained dormant Aztanti traits that had the potential for greater strength, intelligence, and lifespans. In [[UpliftedAnimal force evolving]] the Thralls into their current state, Beatrix simply reawakened these dormant traits but just enough to make them into a SlaveRace for the Jennerit.]]
* ''Videogame/{{Diablo}}'': ''VideoGame/ChronoTrigger'' features a {{Downplayed|Trope}} version. AfterTheEnd, the remnants of humanity huddle in filthy shelters, hiding from the killer robots and mutants that roam the ruined cities. Very little food remains, and the survivors, dressed in tattered rags and with wildly unkempt hair, are largely reliant upon {{Autodoc}}s to keep them alive, though this does nothing about their gnawing hunger.
* ''VideoGame/{{Diablo}}'':
Humans are the descendants of an ancient race known as the [[{{Nephilim}} Nephalem]], who are described as a half-breed race born from forbidden unions between angels and demons, with [[ImmuneToFate no fixed destiny]] and limitless potential that even the mightiest Demon Lords and Archangels felt threatened by. The angels and demons who sired them became so afraid of them that they modified an artefact called the Worldstone into a PowerLimiter, causing the second generation on Nephalem to be born considerably weaker and with much shorter lifespans than the first. At the end of ''Videogame/DiabloII'', the Worldstone is corrupted and shattered, and 20 years later, [[HumansAreSpecial a small number of humans were starting to regain their Nephalem-like potential.]] Unfortunately, thanks to the actions of a renegade sect of angels, the vast majority of humanity was wiped out, severely slowing the restoration of humanity's ancestral potential. As of ''Videogame/DiabloIV'', fifty years afterwards, there have been no new cases of humans awakening Nephalem powers yet seen, forcing what remains of human society into the most primitive and diminished state it had been in thousands of years.

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