History Main / EekAMouse

[[caption-width-right:232:[[FurryConfusion Hey, you might freak out too if you saw a tiny human running across your floor.]]]]

* The eponymous ''Manga/{{Doraemon}}''; rightfully so, as a mouse chewed off his ears.

* In ''ComicStrip/{{Dilbert}}'', Dawn the Dinosaur has this reaction to meeting Ratbert, jumping on her husband Bob's head. [[ComicallyMissingThePoint She chills out upon being told that he's a rat]].

* Mouse-Man, a Silver Age foe of Comics/WonderWoman, naturally did this one time for one of his schemes, using his mouse motif to scare women into dropping their jewelry. [[SarcasmMode Perhaps not the greatest triumph for feminism]] to occur in ''Wonder Woman''.

* In ''VideoGame/Deltarune'' Chapter 2, Noelle freaks out at seeing mice in Cyber City, especially in the puzzles where Kris has to move rotating tiles to lead them from one hole to another. She'll even tease Kris for "deliberately" scaring her with the mice if they fail to solve the puzzle several times.

* ''Film/EightHeadsInADuffelBag'': The two female leads take this kind of behavior UpToEleven when they find a disembodied head in their luggage during a family vacation. ("Eek, a Head!"?) One shuts herself up in a closet and refuses to come out (until the protagonist jokingly suggests that the dead guy's body might be in there), while the other ''attacks the protagonist with a fork''. The latter is especially hilarious because what causes her to snap is the protagonist innocently asking, "Would you like an enchilada?"

* ''Series/TheNoddyShop'' turns this into a running gag for Aunt Agatha, with her thinking the goblins are rodents. One episode, "The Fish Story", has her take it UpToEleven by dressing up as a cat to scare away mice that she believes stole a ring belonging to Kate's mother.

* The protagonist of ''ComicBook/JenniferBlood'' takes advantage of this stereotype in issue 3, when a neighbor who's convinced she's attracted to him has cornered her in a bathroom and exposed himself to her. She doesn't want to ruin her "perfectly ordinary suburban housewife" facade by maiming or killing him, but as someone who moonlights as a brutal {{Vigilante}}, that's all she's trained to do. So she starts shrieking about a pretend mouse.

* In ''Fanfic/TheGreatAlicornHunt'', Rarity has this reaction to [[FriendToAllLivingThings Mudpuppy's]] managerie in chapter 26.

* ''WesternAnimation/ThomasAndFriends'' "[[Recap/ThomasTheTankEngineS6E21ThomasPercyAndTheSqueak Thomas, Percy and the Squeak]]": Opera singer Alicia Botti shrieks upon seeing a mouse in one of Thomas' coaches. She shrieks so loudly, in fact, that she ''[[GlassShatteringSound shatters windows all over the town]]''.

* ''WesternAnimation/ThomasTheTankEngine'' "[[Recap/ThomasTheTankEngineS6E21ThomasPercyAndTheSqueak Thomas, Percy and the Squeak]]": Opera singer Alicia Botti shrieks upon seeing a mouse in one of Thomas' coaches. She shrieks so loudly, in fact, that she ''[[GlassShatteringSound shatters windows all over the town]]''.

See also CowerPower and WhyDidItHaveToBeSnakes. May overlap with ScreamsLikeALittleGirl. See also YouDirtyRat. Contrast NiceMice. In Japanese media, frogs are often used instead. Supertrope to ElephantsAreScaredOfMice.

** In ''VideoGame/FireEmblemAwakening'', the mere sight of a -apparently huge- bug flitting around sends Lucina and Cynthia -two experienced warriors who have survived a zombie apocalypse- into a panic.
--->'''Lucina:''' Breathe, Cynthia. Calm down and tell me what happened. You have nothing to fear now that I'm here.\\
'''Cynthia:''' B-b-bug! A bug!\\

'''Cynthia:''' As in a huge, freakish nightmare, with gross, hairy legs... It's HORRIBLE!\\

'''Cynthia:''' AAAAAH! It's back! And it can fly?! S-stay away! Don't come near meee!\\

'''Cynthia:''' See? SEE?! It's the stuff of nightmares! Now hurry up and kill it! Kill it with fire magic or something!\\

* ''Film/OceanWaif'': Millie jumps under the covers of a bed in terror after seeing mice leaving a mouse hole in the mansion.

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* ''Series/MyWifeAndKids'': In "Of Mice and Men", Jay finds mouse droppings in the house and demands that Michael hire an exterminator to get rid of them, but, as usual, Michael is determined to handle it himself. HilartityEnsues.

[[folder:Puppet Shows]]
* In ''Series/{{Thunderbirds}}'', The Hood sneaks a camera disguised as a mouse aboard ''Thunderbird 2''. The plot fails because it was attracted to, and only photographed, the screaming Lady Penelope. And The Hood never gets to try again since he destroys the mechanical mouse in a fit of rage.
[[/folder]]

* ''A Challenge of Arms'' had a ''mastodon'' that is afraid of mice.

* ''VideoGame/TheLegendOfZeldaSpiritTracks'': Princess Zelda reacts to mice in this manner. Seeing her cower like this is a bit silly when she's [[BodySurf animating a steel-clad Phantom]]. This is why stage 2 of the final battle has Link having to take down the ghost mice used to attack Zelda by Chancellor Cole.
* ''VideoGame/GalaxyAngel'': Played with as, in an AmazonBrigade full of girly-girls, the one with the paralyzing phobia of mice is the [[MightyGlacier powerful]] and [[BoobsOfSteel intimidating]], [[RareGuns Rare Gun]]-collecting, ultra-violent {{Bifauxnen}} Forte.
* ''VideoGame/WildArms1'': [=HanPan=] uses this to his advantage in several places in the game to spook certain [=NPCs=] and make them move.

* Mongoria from ''VideoGame/ComixZone'', an otherwise extremely formidable enemy, had this as her weakness. Drop Roadkill, Sketch's pet rat, in front of her and she'll actually say the trope name before jumping off the page.
* Elh from ''VideoGame/{{Solatorobo}}'' absolutely ''hates'' bugs and insists that Red kill them as quickly as possible when you come upon them (which is a good idea, since the bugs attack you [[EverythingTryingToKillYou like most everything else in video games]]). There are also ''two'' {{Protection Mission}}s in which the goal is just "don't let the bugs get near Elh" (this includes if you accidentally throw a bug across the line because apparently even a dead bug is creepy).
* Played with for a laugh in ''VideoGame/FinalFantasyIX''. [[KingIncognito Incognito princess]] Garnet picks up an oglop (a beetle-like insect), having no problem with the little critter whatsoever. However, since she's supposed to be undercover as a normal country girl when an old woman comments that most girls hate them, she squeals theatrically and flings it into the air. Meanwhile, the Knights of Pluto -- doughty bodyguard Steiner included -- positively flip out when confronted with the bugs.

* ''VideoGame/TheBardsTale'': This can be invoked for rewards in the [=PS2=] release by summoning and dismissing the rat in bars. In fact, this is how the eponymous Bard starts the game.
* ''VideoGame/TalesOfGraces'': In a skit in the UpdatedRerelease, ''Tales of Graces f'', Cheria is freaked when Sophie discovers a mouse in Pascal's invention, Mecha-Asbel.
* ''VideoGame/ChronoTrigger'': Frog manages to frighten Lucca when they first meet. Later, if Marle is in the party when Crono and Lucca see him off from Guardia Castle, he'll approach Marle to comment on her resemblance to Leene, prompting her to shriek.
* In ''VideoGame/BrainLord'', Ferris screams her head off when she encounters a room full of mice in the Tower of Light.
* ''VisualNovel/Danganronpa2GoodbyeDespair'': Monomi and Monokuma are revealed to be terrified of mice in chapter 4.
* ''VideoGame/TheWitcher3WildHunt'': An amusing fantasy equivalent happens when, while exploring a ruin with Keira Metz as part of a sidequest, Geralt ends up separated from her and hears her screaming for help. He finds her encased in a magical shield, between two rat nests with the critters scurrying around her feet. As Geralt points out, she is a master sorceress who could've wiped them out with a mere twirl of her wrist.
* ''VideoGame/ConkersBadFurDay'': In the "Barn Boys" chapter, the larger female block standing on top of Jack is afraid of mice, and in order to get her off him, Conker has to get rid of Marvin the Mouse. To do so, Conker has to feed Marvin [[RuleOfThree three]] pieces of cheese. After the third piece, Marvin becomes so gassy that [[PopGoesTheHuman he inflates and explodes]].[[note]][[UnexplainedRecovery Marvin returns fully healed]], though badly scarred and stitched together at the end of the game.[[/note]]
* In ''VideoGame/TouhouSeirensenUndefinedFantasticObject'', upon encountering Nazrin, Sanae has this reaction, nearly word-for-word.

* ''VideoGame/AmazonGuardiansOfEden'': Darlene is afraid of rats which is why she hates Jason's work. When a rat is placed next to her by him, she shrieks, lifts her hands, and runs away.
* In ''VideoGame/TheAdventuresOfWillyBeamish'', Ms. Glass leaps onto her desk and shrieks for the school principal if Willy reveals Horny's presence in his backpack.

* Referenced in ''WesternAnimation/SouthPark'' episode "Eek, A Penis!" where a mouse with a genetically engineered human penis growing on its back frightened women. Actually they were frightened by the penis (and who wouldn't be--even if a mouse or a human penis wouldn't freak you out, seriously, a ''mouse with a human penis growing out of its back''?). But the trope still stands.

* ''WesternAnimation/TomAndJerry'': Done many times.
** In one short, the "eeker" is Tom's cowardly identical cousin.
** Averted in one episode when the lady who owns Tom ''buys'' a pet white mouse (actually Jerry painted white that Tom had sold to the pet store earlier in the cartoon).

* In ''WesternAnimation/TheChickenFromOuterSpace'', the pilot to ''WesternAnimation/CourageTheCowardlyDog'', Courage was afraid of a mouse in the beginning. Muriel plucks the little rodent and sets it loose outdoors. But after the battle with the titular chicken from outer space, we see Courage looking at it again as it fed on the ashes of the fallen fowl. [[RedEyesTakeWarning The mouse's eyes turn bright red]] as a result. It was a JustifiedTrope as Courage screams in terror.
-->'''Courage:''' This shouldn't happen to a dog!
* ''WesternAnimation/FiremanSam'': Bella often freaks on seeing mice, regardless as to whether they're real or clockwork ones.
* ''WesternAnimation/ThePowerpuffGirls': Taken to ridiculous lengths in an episode where a rivaling villain reanimates a mammoth (which appears as comically large as any city-destroying monster) to cause destruction in Townsville. To stop it, Mojo Jojo instructs the girls to leave a large hunk of cheese to attract the town's mice and scare the mammoth off. And you know what? It works!
* Creator/TexAvery, naturally, built an entire cartoon out of this trope. "Slap Happy Lion" has a mouse scaring a much-feared lion simply by saying "Boo!" at him. The cartoon ends with the mouse being scared by a much smaller mouse. The narrator of that cartoon -- a mouse -- even wonders why anyone would fear a mouse.

* ''WesternAnimation/TransformersAnimated'': When Captain Fanzone winds up on Cybertron, this is basically the Transformers' response.
* ''ComicStrip/KrazyKat'': In "Krazy Kat and Ignatz Mouse at the Circus", Ignatz [[InvokedTrope knowingly employs this trope]] this to scare a woman in the circus dressing room. When Krazy tries it himself, he gets hit with a broom.
* ''WesternAnimation/WhoKilledWho'' has a ghost who scares the protagonist, laughs, then promptly gets scared of a tiny mouse, in the classic housewife way.

* ''WesternAnimation/ProducingParker'': Employed and then subverted when Parker shrieks at the sight of a mouse in Dee's office. Dee, who has been turned into a human/reptile hybrid by experimental snake venom-based drugs, promptly [[{{Squick}} claps her jaws shut on the little critter and gulps it down]].
* ''WesternAnimation/{{Arthur}}'': The opening teaser of "Pets and Pests" has the entire Read family, sans Baby Kate, demonstrate a highly over-exaggerated version of this when Dad unveils his banana bread and there's a mouse on it. It ends with them all running out of the kitchen screaming, only for Mrs. Read to run back in and grab Baby Kate.
* ''WesternAnimation/DextersLaboratory'': In "Mom & Jerry", Dexter accidentally swaps his brain with that of a lab mouse. HilarityEnsues when Dexter (in the mouse's body) ends up in the kitchen, causing his mother to freak out and start trying to chase him out of the house.
* ''WesternAnimation/{{Caillou}}'': In "Leo's Hamster", this is done with a hamster when Leo's hamster, Buddy, whom Caillou is petsitting, gets loose.
-->'''Caillou''': Mommy, why are you standing on the chair?\\
'''Mommy''': Me? (''giggles nervously'') Oh, no reason.
* ''Literature/LittlePrincess'': In "I Want a Sleepover", when the "dragon" that Algie and Little Princess discover actually turns out to be a family of mice, Maid screams as if there actually is a dragon.
* ''WesternAnimation/JackieChanAdventures'': In "Tough Luck", Finn has a TerribleIntervieweesMontage while trying to find minions. One of the applicants displays impressive swordsmanship, but when Finn is about to hire him, the man shrieks at the sight of a mouse and runs away.

* In ''WesternAnimation/TheCrumpets'' "Ghosts In The Attic", up in the attic of the house, Caprice freaks out thinking there's mice when it's in fact her young twin siblings sneaking through her. Later at the preparation of the voodoo ceremony, however, Granny holds a mouse in front of Caprice and the latter finds it cute.
* ''WesternAnimation/TheRealGhostbusters'' episode "Stay Tooned" had Janine freak out after seeing a cartoon cat and a cartoon mouse come to life and leap out of the television set. When the Ghostbusters ask her what happened, she stammers "I...I saw a mouse", causing them to initially think that Janine was scared by an ordinary mouse.
* ''WesternAnimation/{{Gasp}}'': In "Mouse Fishin'", a mouse scares Ginger out of the kitchen. This sets in motion the episode's ZanyScheme as Gasp ropes the pets into helping him capture and then evicting the mouse.
* ''WesternAnimation/ChipAndPotato'':
** Potato is a mouse but only Chip knows this, and all of the other characters think that she's her [[SecretIdentity snuggly toy]] that she totes around with her everywhere. It's [[ImpliedTrope implied]] that Chip keeps Potato a secret because the other characters would react this way if they believed her to be a real live mouse.
** Sure enough, this happens in "Chip's School Trip" after Chip is forced to leave behind Potato in a dollhouse in a museum. To the point that there's a scream and a [[ExaggeratedTrope man comes on a loudspeaker telling everyone to make their way to the exit.]] Then, when Howie opens up Chip's lunch bag, he spots Potato in her mouse form, screams, and tosses the bag and sends everyone else into a panic.
** When Chip first reveals the truth to Nico in "Hospital Trip Chip," he tells her to call the nurse, but after realizing what's going on calms down.
* ''WesternAnimation/CentralPark'': In "[[Recap/CentralParkS1E4GarbageBallet Garbage Ballet]]", Paige hates rats and the garbage crisis at the park increased her fear due to the increased rats in the park. Paige spends their sick time setting traps if any rats enter her home while Cole stays home to stop her. In the end, she was just hallucinating the rats in her house due to her flu.
* The first ''WesternAnimation/{{Madeline}}'' special introduces Madeline's fondness for mice by showing her happily playing with them in the kitchen while the other little girls all quake and "Eek!" on top of a stool (where somehow [[CartoonPhysics all eleven of them fit]]). Later, the nurse at the hospital also cries "Eek!" when Madeline asks for some mice to play with.

* ''Series/ThreesCompany'':
** "The Best Laid Plans" revolves a mouse being loose in the trio's apartment. Larry kills the mouse, but Jack doesn't want the girls to find out because Janet won't sleep in her bed as long as the mouse is around and Jack is using it as an excuse to sleep in the same room as Chrissy. Meanwhile, Mr. Roper doesn't want Helen to know the mouse is dead because he was using it as an excuse for Helen's mother to not visit.
** ''Series/TheRopers'' features a gender-flipped version of this trope: it was ''Mr.'' Brooks, not his wife, who leaped up onto the couch screaming at the sight of a white mouse--safely in a cage, no less.
* ''Series/{{Monk}}'': Adrian Monk frequently [[ScreamsLikeALittleGirl reacts this way]] to a variety of analogous situations. Justified in the episode when it was a ''venomous snake'' that was loose in the room.
* ''Series/HopeAndFaith'': Played with. When the two title characters get office jobs together, the ever-immature Faith dangles her computer mouse into Hope's cubicle and yells this trope name.
* ''Series/TheGoldenGirls'' had one, revealing why Dorothy's nickname is Pussycat. Instead of catching it as the other girls expect her to, Dorothy talks the mouse into escaping.

* ''Series/XenaWarriorPrincess'': Gabrielle (not ''quite'' an ActionGirl yet) is hiding from some bad guys when she notices a rat crawling about. She has to remain perfectly still and silent lest she blows her cover, and HilarityEnsues as she stares at it with wide eyes and covers her mouth before a whimper comes out.
* ''Series/UnhappilyEverAfter'': Double-subverted. Ryan, who believes the old legend that the Earth would spin out of its orbit if all the Chinese people in the world jumped off their chairs at the same time, panics when he spies a group of Chinese exchange students standing on their chairs in the school cafeteria. One of the students explains that they had just seen a mouse, causing Ryan to calm down. Once Ryan is gone, though, the student gets angry and mutters: "Curses! They're onto us!"

-->'''Grant:''' ''[upon realizing he lost track of the mice]'' [[OhCrap Where did you go? WHERE DID YOU GO?]]
* ''Series/ElChavoDelOcho'':
** One episode has Quico playing with a mouse while snickering -- and later Dona Florinda and La Chilindrina screaming and fainting due to the mouse.
** A late episode has Doña Florinda's restaurant plagued by mice. She and Chilindrina exhibit the expected reaction throughout, especially in a hilarious scene where Chavo unknowingly brushes the latter's leg with the broom he is using to hunt the mouse; she has an absolute panic attack, thinking it's the mouse climbing up her leg.
%%* ''Series/FraggleRock'': This is how Ma Gorg reacts to Fraggles.
* In ''Series/{{Community}}'' episode [[Recap/CommunityS1E10EnvironmentalScience Environmental Science]] Troy freaks out when a lab rat accidentally escapes.
* ''Series/{{Carrusel}}'': [[ThePrankster Pablo]] releases a mouse in the middle of class. All but one of the girls start screaming and crying. [[spoiler: The one girl who isn't scared, [[{{Tsundere}} Valeria]], "punishes" Pablo by pretending to pass out and tricking him into believing she had a heart attack.]]
* ''Series/SexAndTheCity'': In one episode, Charlotte dates a CampStraight man and they both react to a mouse in a similar way.

* ''Series/BuffyTheVampireSlayer'':
** Averted in the premiere episode. The heroine doesn't even twitch when a sewer rat runs over her foot.
** Buffy does jump at a sewer rat in "I Will Remember You", but that's a sign that she's nervous over [[UnresolvedSexualTension working closely with Angel]].
** Inverted in ''Series/{{Angel}}'' when Gunn and Wesley freak out over a rat and Cordelia is the one to get up and deal with it.
%%* ''Series/MyWifeAndKids'': "Of Mice and Men".
* ''Series/TheTonightShow'': In one episode, Johnny Carson freaks and jumps into Ed [=McMahon=]'s arms after a cheetah cub hisses at him.
* ''Series/TheMentalist'': Jane once escaped from jail by scaring a rodent-phobic guard with a live mouse he'd caught.
* In ''Series/OrangeIsTheNewBlack,'' this gets played straight in season 6 when the girls of D block dump rats into the prison's cheese business as a Halloween prank to get at their rivals in C block. Everyone freaks out like expected, and it kills one of the cushiest jobs C block had while also killing a pipeline D block had to smuggle drugs.
* ''Series/TheWorstWitch'': Exploited when Helibore and Rowan-Webb have a wizard duel (no not [[Franchise/HarryPotter like that one]]). Helibore turns Ethel into a goose girl and Rowan-Webb counters by turning himself into a mouse to scare her.

* ''Series/TheBradyBunch'':
** Happens with Alice on when a pet mouse gets loose. Although it's averted another time -- she hands it to the boys and isn't scared.
** In a different episode, Cindy runs into the kitchen asking Alice if she has seen her pet lizard that escaped its box. Through a clenched-teeth smile, Alice answers, "Yes I have. He's over there." Camera zooms out to reveal that Alice is standing on the table.
** Invoked and subverted in a third episode. Bobby and Cindy complain to Emma that there is a mouse in the house. Emma tells them to make a pet out of it. Bobby and Cindy are shown petting it and clearly not afraid of it.
* ''Series/{{Dollhouse}}''. At the start of Season 2, a pissed-off Dr Saunders puts lab rats in Topher's cupboard, in a not-too-subtle message of what she thinks of him. His female assistant Ivy has to retrieve them while Topher climbs the nearest railing to get away.
* ''Series/DangerUXB''. A sapper screams when he encounters a rat, just when Lieutenant Ash is about to defuse a bomb designed to blow up at the slightest touch. He is not amused.
* ''Series/{{Bewitched}}'': Cousin Serena both invokes and inverts the trope when, while talking about a woman she finds disgusting, she comments about how mice are likely horrified by ''her''.
-->''I'll bet when the mice see her, ''they'' climb up on chairs.''

* A ''Series/{{MASH}}'' episode has Hawkeye reacting this way to Radar's pet mouse. When they enter her in a race against group of Marine patients, Hawkeye screws up the courage to "pet her for good luck"... and one tiny stroke is enough to set him grimacing and cowering away.
* ''Series/OdiseaBurbujas'': Mimoso Raton (a baby mouse) is shown entering a room during his theme song. A woman jumps up onto a chair because she is afraid of him- and presumably of mice in general.
* ''Series/TheNoddyShop'' turns this into a running gag for Aunt Agatha, with her thinking the goblins are rodents. One episode, "The Fish Story", has her take it UpToEleven by dressing up as a cat to scare away mice that she believes stole a ring belonging to Kate's mother.
* In ''Series/VelVet'', Clara shrieks when she sees a rat. Her sister Rita does not even flinch. The supervisor, Emilio, thinks it is probably just a mouse- but he orders the crew to hunt down the rodent just in case. Eventually, Rita catches it while Luisa and Ana shriek- and it turns out to be just a cute little mouse!

* In ''Manga/HayateTheCombatButler'', Maria is scared of cockroaches (they even have a nickname within the story so they can be talked about around her). Shiranui brings one into the house and she shrieks standing on Hayate until he apparently shoos the kitten away. Still trying to figure out how he did anything with her standing on him like that. [[HandWave But don't worry]], [[RunningGag he trains]].
* In ''Anime/SaberMarionetteJ'', in order to make the marionette robots as much like (stereotypical) women as possible, every one of them is programmed to be afraid of mice -- except the tomboyish Lime, who merely finds them cute. This actually saves the heroes in one episode, when Cherry (reluctantly) punches the cave's ceiling and makes a ''whole colony'' of mice fall on them, sending Tiger and Panther running away in fear.

* In the ''Anime/MobileSuitGundamSEED'' VisualNovel ''Tomo to Kimi to Senjou de'', Athrun decides to make a robot pet for his crush Cagalli. He ends up giving it a hamster design, but when she first sees it she has this reaction and smashes it. Kira steps in and explains, and Cagalli is both very touched by the gesture and very apologetic for destroying it.
* ''Manga/InuYasha'': Kagome can handle {{youkai}}, blood, guts, wounds, two-timing boyfriends, time-travel, saving the world while trying to pass exams, lifting the spirits of the depressed, downtrodden, and bullied and can even befriend the reclusive, the painfully shy, and aggressively hostile, but ask her to help a giant beast-faced [[HalfHumanHybrid hanyou]] in his herb garden when there's an earthworm in plain sight and she'll fall to pieces.
* In ''Manga/DragonBall'', Goku is fighting General Blue of the Red Ribbon Army. Blue has Goku paralyzed with telekinesis and is about to finish him off... when a small mouse appears. Blue flips his lid, freaks out and loses focus. Goku is grateful enough for the unwitting save that he rescues the mouse when the cave they're fighting in collapses.
* ''Manga/AiYoriAoshi'': Miyabi is capable of bodily throwing someone across the room if she even ''suspects'' someone is trying to [[MamaBear harm Aoi]], but completely flips her lid at the sight of bugs. Unfortunately for her, the Sakuraba house's pet ferret, Uzume, develops a habit of bringing her dead bugs.
* The titular ''Manga/{{Doraemon}}''; rightfully so, as a mouse chewed off his ears.
* ''Manga/DontMeddleWithMyDaughter'': Athena is the world's greatest superheroine and [[FlyingBrick a seemingly unstoppable force]] of justice... except she's still [[WeaksauceWeakness scared of mice.]] So it's good that it isn't something she often has to deal with.

* In ''Anime/ArabianNightsAdventuresOfSinbad'', Tabasa the witch is terrified of mice, which Sinbad uses against her more than once.

* ''Franchise/{{Tintin}}''. Thomson and Thompson are startled by mice used for experiments in ''Recap/TintinDestinationMoon''.

* In ''ComicBook/{{Violine}}'', this happens several times to several characters, though not with Violine's pet mouse, only with other groups of mice.

* ''ComicStrip/CalvinAndHobbes'': Calvin once tried to gross out Hobbes by telling him he had a loathsome bug hidden in his hands. When Hobbes asked if it was a centipede with poison pincers, Calvin did an OhCrap, dropped the bug, and jumped into Hobbes's arms, declaring: "It's a lucky thing you guessed so fast!"
* The Dog's reaction to rats in ''ComicStrip/FootrotFlats''. The cat, Horse, has the opposite reaction.
* ''ComicStrip/DykesToWatchOutFor'' used an example with a bat to play with stereotypes: the LipstickLesbian is shooing the bat away with a tennis racket while her {{butch|Lesbian}} partner cowers under a blanket: "Don't let it get my beer can collection!"
* One ''ComicStrip/{{Popeye}}'' strip has Olive Oyl freaking out when she saw a mouse, tearing up her living room trying to get away from it. Upon seeing this, Popeye declares, "Well, it's a dern good thing ya didn't see a hippitypotamusk! Pooey! I yam disgustipated!"

* ''[[Fanfic/TheRockFarmersDaughters The Rock Farmer's Daughters]]'': Taken to an unusual extreme in the chapter titled "Unusual Incentive": [[spoiler:Marble opens a cupboard, and a waterfall of mice ends up falling onto her head, while everypony else finds mice seeping out of every nook and cranny. Cut to Igneous and Maud outside, hearing Marble shriek. She spends most of the chapter curled up on the table while the others drive the mice out of the house]].
* In ''Fanfic/TheMoreThingsChangeSeries'', Maria Novak, the first person La Fay [[DemonicPossession possesses]] has a deep fear of all rodents. Unfortunately, Le Fay can't override such weaknesses and as such, becomes crippled with fear at the sight of Rufus, something Kim and Ron take advantage of while fighting her.
* In ''Fanfic/TheGreatAlicornHunt'', Rarity has this reaction to [[FriendToAllLivingThings Mudpuppy's]] managerie in chapter 26.

* ''WesternAnimation/TitanicTheLegendGoesOn'' had a scene where Angelica's stepsisters were scared by mouse.
* ''WesternAnimation/{{Ratatouille}}'' plays this trope straight too.

* In ''WesternAnimation/CinderellaIIIATwistInTime,'' Jaq and Gus help Cinderella get into the palace by scaring the kitchen servants while Cinderella poses as the "royal mousecatcher".

* ''Literature/TheMouseThatRoared'': The film opens with the Columbia Studios girl-with-torch logo suddenly hiking up her gown and fleeing from a mouse at her feet. (The title is a metaphor for a tiny, innocuous nation that ends up holding the fate of the world in its hands.)

* In ''Film/ShesTheMan'', Duke and Viola scream and leap on the bed, hugging each other, when a big spider enters their dorm room.
* ''Film/EightHeadsInADuffelBag'': The two female leads take this kind of behavior UpToEleven when they find a disembodied head in their luggage during a family vacation. ("Eek, a Head!"?) One shuts herself up in a closet and refuses to come out (until the protagonist jokingly suggests that the dead guy's body might be in there), while the other ''attacks the protagonist with a fork''. The latter is especially hilarious because what causes her to snap is the protagonist innocently asking, "Would you like an enchilada?"
* ''Film/FridayThe13thPart2'': PlayedForDrama. While hiding under a bed from Jason, a rat crawls up to Ginny's face. This causes Ginny to wet herself, informing Jason of her presence under the bed by a trickle of urine coming down from the bed. However, according to the director, it was the rat that did it.

* In one scene in ''Film/{{Willow}}'', a woman shrieks at the sight of mouse-sized humanoid creatures called brownies.
* Happens a few times in some ''Film/TheThreeStooges'' shorts. Justified for the time period.
** Perhaps the most famous is in "Horses’ Collars", where, any time Curly sees a mouse, he flies into a violent rage while screaming, "Moe, Larry, the cheese!" The other two Stooges have to feed him cheese to calm him down.
* Invoked by Becky in the Alfonso Cuaron version of ''Film/ALittlePrincess''. As the students are stealing Sarah's locket from Miss Minchin's office, Becky screams to distract Minchin and eventually stammers that she thought she saw a mouse.
* Lt. Alexis in ''Film/TheWildcat'' is TheCasanova to an absurd extreme. When it's time for him to leave for his next duty station on the frontier, literally hundreds of women throng the streets, obstructing his car. The other soldiers finally get the crowd of ladies to disperse by dumping a barrel of mice.
* ''Film/TheNameOfTheRose''. The monks hear a shriek, then laugh at a CampGay monk on top of a stool with a mouse below. They quickly shut up when an elder friar starts shouting at them. [[spoiler:This turns out to be a ChekhovsGun re the motive of the killer, who hates laughter.]]
* Subverted in ''Film/PhaseIV''. A woman screams when she sees a mouse wandering around in the desert via a closed-circuit video screen. Then she and the other characters gape in horror as they watch the ants quickly devour the entire mouse in a matter of seconds.

* In ''Film/HussarBallad'', SweetPollyOliver Shura fearlessly fights French soldiers throughout the entire film, being vastly outnumbered most of the times, but shrieks and faints at the sight of a mouse.
* ''Film/MyScienceProject'': While Michael is exploring the abandoned fallout shelter in the aircraft boneyard, Ellie sees a rat and screams, attracting the attention of a security guard. He has to coax her off the piece of machinery she's climbed onto before they can flee.
* In ''Film/TheHazing'', Delia acts like this when she tries to collect the TerrifyingPetStoreRat for the ScavengerHunt; especially after it somehow gets tangled in her hair. While this might have been part of her ObfuscatingStupidity, she squeals again when the rat comes through the portal after she has dropped her DumbBlonde act, so it's possible that she actually is scared of rodents.

* In ''[[Literature/LandOfOz The Marvelous Land of Oz]]'', Scarecrow and his friends enter his palace (taken by rebels), and are captured immediately, to be brought before their leader. However: 1) the rebels are all women and 2) Scarecrow has recently met the Queen of the Field Mice and asked for permission to take a few of her subjects along.
* In ''Literature/TheWitches'' Bruno's mother flips into hysterics when the [[spoiler: witches start turning into mice thanks to drinking their own potion]]. She literally climbs over her husband screaming about them climbing up her skirt. Although in this case, it's completely understandable since there are over a '''hundred''' of them running around.
** The reason that the potion transforms children into mice in the first place is because the Grand High Witch hopes to exploit this trope, thinking the mouse-children will be so revolting that their teachers will kill them.

* The non-fiction book that inspired ''Series/HomicideLifeOnTheStreet'' mentions that one of the detectives had been called home by his wife to deal with a rampaging mouse. "I disposed of the body, but considered leaving it as an example to others."

* In ''Literature/TheChroniclesOfNarnia'', BadassAdorable Talking Mouse Reepicheep wants to be a herald, but he's too small to be seen until he's up close (and therefore not very impressive). Of course, since he's [[BerserkButton very touchy]] [[HonorBeforeReason when it comes to his honor]], nobody wants to tell him this, so they tell him that it wouldn't be quite fair to their enemies since some humans are afraid of mice.
* In ''Literature/{{Mousenet}}'', this is part of the "EEEK Test," a test used by mice to gauge a humans' feelings towards mice. Jumping on a chair results in a "Loud EEEK" and a grade of C, with fainting being the worst possible response and earning an F. Talking to or touching the mouse is "No EEEK" and an A+.

* ''The Bronze Horseman'' by Paullina Simons. Alexander is rather bemused when his young wife Tatiana has this reaction, as he's seen her brave 500-kg bombs, cannibals, and starvation in the Siege of Leningrad. He points out that mice can climb, so standing on the furniture does no good.
* ''Franchise/DocSavage'': There is an odd OutOfCharacterMoment in ''Land of Long Juju'' (not one of the better books in the series) where ActionGirl Pat Savage has to restrain herself from flinching when several field rats scamper out of the jungle.
* ''{{Literature/Animorphs}}'':
** Naturally averted with Cassie, who works with animals every day. One story has Marco wonder how you can tell a female Hork-Bajir from a male, such as being weird around bugs and snakes. Cassie raises an eyebrow and throws a (harmless) snake at him. Marco ScreamsLikeALittleGirl.
** Genderflipped when Cassie morphs a rat to figure out why it won't complete a maze when two dumbasses enter the lab and try to kill the rat. [[SquirrelsInMyPants She runs up their pants legs to get them to leave.]]
** Played straight when Marco gets Ax to morph a mouse with him so he can eavesdrop on a girl who didn't invite him to a party. On finding out why she didn't invite him ([[ToiletHumor it involved a prank with a chocolate bar and a pool]]) he runs across her toes, prompting mass panic in the girls, macho bravado from the boys, and annoyance from Jake and Cassie, who very quickly catch on when the mice seem to understand English.
* ''Literature/InTheRealmsOfTheUnreal'' by Creator/HenryDarger has a hysterical escapade where the little princesses of Abbiennia sneak into a meeting of evil Glandelinian higher-ups and release a bunch of mice. The men shriek and cower and get up on chairs and tables.
* In the [[https://schlock-value.com/2013/10/20/the-feminists/ schlock novel]] ''The Feminists'' by Parley J. Cooper, both the [[StrawFeminist Straw Feminazi]] authorities and LaResistance have such an irrational fear of rats they won't even mention the word. This causes problems when LaResistance have to hide in the sewers.

* ''Literature/AspergerAdventures'': In ''Lisa and the Lacemaker'', Lisa shows Granny May her mouse Paddy, thinking she'll be interested. Instead, Granny May screams and drops her teacup.

** [[https://garfield.com/comic/1979/01/18 This]] strip, where Garfield screams and scurries up onto Jon's head upon seeing a mouse -- and Jon is disgusted because Garfield is a ''cat''.
** Referenced in [[https://garfield.com/comic/1984/11/01 this Garfield comic]], when a mouse claims people call him "Eek".
** Referenced in [[https://garfield.com/comic/1996/03/09 this comic]].
** [[https://garfield.com/comic/2004/09/09 Garfield did it in consideration for the mouse's birthday.]]
** [[https://garfield.com/comic/2009/08/24 Jon yelled "Eeeeeeek!"]] then he said "Um... I mean, get the mouse." Garfield said it'd go into his blog.
* ''ComicStrip/USAcres'': [[http://garfield.com/us-acres/1988-07-16 A worm had this reaction after entering a mouse hole to hide from Booker.]]